Result of FASTA (omim) for
pFN21AE1322
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1322, 218 aa
1>>>pF1KE1322 218 - 218 aa - 218 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2922+/-0.000373; mu= 13.8908+/- 0.023
mean_var=68.5553+/-13.587, 0's: 0 Z-trim(113.6): 41 B-trim: 39 in 1/51
Lambda= 0.154901
statistics sampled from 23024 (23064) to 23024 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.27), width: 16
Scan time: 4.860
The best scores are: opt bits E(85289)
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 1493 342.4 3.4e-94
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 1332 306.5 2.3e-83
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 1300 299.3 2.9e-81
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 1301 299.6 3.1e-81
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 1281 295.1 6.1e-80
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 1234 284.6 8.9e-77
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 1234 284.6 8.9e-77
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 1122 259.5 2.7e-69
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 1112 257.3 1.5e-68
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 1107 256.1 2.8e-68
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 1091 252.5 3.1e-67
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 918 213.9 1.4e-55
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 899 209.7 3e-54
XP_016856577 (OMIM: 138333) PREDICTED: glutathione ( 150) 598 142.3 4e-34
XP_005270842 (OMIM: 138385) PREDICTED: glutathione ( 114) 572 136.4 1.8e-32
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 345 85.9 5.5e-17
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 266 68.2 1.1e-11
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 212 56.2 5.1e-08
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 212 56.2 5.1e-08
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 201 53.7 2.8e-07
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 197 52.8 5.2e-07
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 195 52.4 7.1e-07
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 183 49.7 4.6e-06
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 183 49.7 4.6e-06
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 180 49.0 6.3e-06
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 180 49.0 6.3e-06
XP_005262989 (OMIM: 602598) PREDICTED: hematopoiet ( 168) 175 47.8 1.3e-05
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 176 48.1 1.4e-05
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 157 43.8 0.00021
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 157 43.8 0.00021
>>NP_000841 (OMIM: 138333) glutathione S-transferase Mu (218 aa)
initn: 1493 init1: 1493 opt: 1493 Z-score: 1812.2 bits: 342.4 E(85289): 3.4e-94
Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
::::::::::::::::::::::::::::::::::::::
NP_000 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
190 200 210
>>NP_000552 (OMIM: 138350) glutathione S-transferase Mu (218 aa)
initn: 1332 init1: 1332 opt: 1332 Z-score: 1617.7 bits: 306.5 E(85289): 2.3e-83
Smith-Waterman score: 1332; 86.7% identity (95.9% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
:::::::::::::::::::::::::::::::::::::::::::.:: ::. .::.:.:
NP_000 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
:::::.:::::: .. .:.::::::::.:.::::::::.::::::::::::.:::::::
NP_000 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::::::::::::::::::.:.....::::::
NP_000 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
190 200 210
>>NP_671489 (OMIM: 138333) glutathione S-transferase Mu (195 aa)
initn: 1300 init1: 1300 opt: 1300 Z-score: 1579.8 bits: 299.3 E(85289): 2.9e-81
Smith-Waterman score: 1300; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::
NP_671 LKDFISRFEVSCGIM
190
>>XP_016856574 (OMIM: 138333) PREDICTED: glutathione S-t (254 aa)
initn: 1300 init1: 1300 opt: 1301 Z-score: 1579.3 bits: 299.6 E(85289): 3.1e-81
Smith-Waterman score: 1301; 94.1% identity (96.1% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
::::::::: . :.:. .:
XP_016 LKDFISRFECSKCSPCEMSSTLILLLFTDLLLCMRQGVRHSGSCIDDCPILEMSAVRGLQ
190 200 210 220 230 240
>>NP_000839 (OMIM: 138380) glutathione S-transferase Mu (218 aa)
initn: 1281 init1: 1281 opt: 1281 Z-score: 1556.1 bits: 295.1 E(85289): 6.1e-80
Smith-Waterman score: 1281; 83.0% identity (95.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: ::::::.::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::.:::::::::: :::::::::::.:.:.:: :::::: :: :::..::.:::
NP_000 PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
::::::::. :: :.. .::::::.:::.:::::::::.:::::. ...:::.:::::::
NP_000 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::::::::::::::::::.:..:..::::::
NP_000 LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
190 200 210
>>NP_000842 (OMIM: 138385) glutathione S-transferase Mu (218 aa)
initn: 1208 init1: 1208 opt: 1234 Z-score: 1499.4 bits: 284.6 E(85289): 8.9e-77
Smith-Waterman score: 1234; 83.0% identity (93.1% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: :::::::::::::::::::::::::: :::::.:::::::::::::::::::::::::
NP_000 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::::::::::::: :::::::::::::::::::::::::.:: .:.:.::.:::
NP_000 PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
:::::.:::::: .. .:.::::::::.::::::::::::::::..:::::.::::: :
NP_000 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::::.:::::::::.:: :. . :.:..:
NP_000 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
190 200 210
>>XP_005270841 (OMIM: 138385) PREDICTED: glutathione S-t (218 aa)
initn: 1208 init1: 1208 opt: 1234 Z-score: 1499.4 bits: 284.6 E(85289): 8.9e-77
Smith-Waterman score: 1234; 83.0% identity (93.1% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: :::::::::::::::::::::::::: :::::.:::::::::::::::::::::::::
XP_005 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::::::::::::: :::::::::::::::::::::::::.:: .:.:.::.:::
XP_005 PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
:::::.:::::: .. .:.::::::::.::::::::::::::::..:::::.::::: :
XP_005 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::::.:::::::::.:: :. . :.:..:
XP_005 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
190 200 210
>>XP_005270839 (OMIM: 138350) PREDICTED: glutathione S-t (184 aa)
initn: 1122 init1: 1122 opt: 1122 Z-score: 1365.2 bits: 259.5 E(85289): 2.7e-69
Smith-Waterman score: 1122; 85.3% identity (96.2% similar) in 184 aa overlap (35-218:1-184)
10 20 30 40 50 60
pF1KE1 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI
::::::::::::::::::::::::::::::
XP_005 MGDAPDYDRSQWLNEKFKLGLDFPNLPYLI
10 20 30
70 80 90 100 110 120
pF1KE1 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLK
:::::::::::::::::::::::::::::::::::::::.:: ::. .::.:.:::::
XP_005 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 PEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNLKDF
:.:::::: .. .:.::::::::.:.::::::::.::::::::::::.:::::::::::
XP_005 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDF
100 110 120 130 140 150
190 200 210
pF1KE1 ISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::::::::::::::.:.....::::::
XP_005 ISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
160 170 180
>>NP_000840 (OMIM: 138390) glutathione S-transferase Mu (225 aa)
initn: 1112 init1: 1112 opt: 1112 Z-score: 1351.8 bits: 257.3 E(85289): 1.5e-68
Smith-Waterman score: 1112; 72.4% identity (89.9% similar) in 217 aa overlap (2-218:6-222)
10 20 30 40 50
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
::.::::::::::::::::::.::.:::::.:: :.::::::::::. :::: ::
NP_000 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCY
:::::::.:: .::::::::: :::::::.:::::::::::::.:::.:: .:: :.::
NP_000 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 SPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
: : :::::.:::::: ....::.:::: ::.:.:.::::::.::.:: .:::.:.:::
NP_000 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
130 140 150 160 170 180
180 190 200 210
pF1KE1 AFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
::::: :. :::.::::.::..:..: :. ...: ::::
NP_000 EFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
190 200 210 220
>>NP_001135840 (OMIM: 138380) glutathione S-transferase (191 aa)
initn: 1107 init1: 1107 opt: 1107 Z-score: 1346.8 bits: 256.1 E(85289): 2.8e-68
Smith-Waterman score: 1107; 83.1% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: ::::::.::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
::::::.:::::::::: :::::::::::.:.:.:: :::::: :: :::..::.:::
NP_001 PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
::::::::. :: :.. .::::::.:::.:::::::::.:::::. ...:::.:::::::
NP_001 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
:::::::::
NP_001 LKDFISRFEHS
190
218 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:53:43 2016 done: Sun Nov 6 22:53:44 2016
Total Scan time: 4.860 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]