Result of FASTA (omim) for
pFN21AB6685
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6685, 427 aa
1>>>pF1KB6685 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2420+/-0.000452; mu= 17.1850+/- 0.028
mean_var=64.7053+/-13.387, 0's: 0 Z-trim(108.1): 134 B-trim: 131 in 1/53
Lambda= 0.159443
statistics sampled from 16093 (16227) to 16093 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.549), E-opt: 0.2 (0.19), width: 16
Scan time: 7.780
The best scores are: opt bits E(85289)
NP_001275962 (OMIM: 147935) kallistatin isoform 2 ( 427) 2798 653.1 4e-187
NP_006206 (OMIM: 147935) kallistatin isoform 2 pre ( 427) 2798 653.1 4e-187
NP_001275961 (OMIM: 147935) kallistatin isoform 1 ( 464) 2798 653.1 4.3e-187
XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 1151 274.2 4.3e-73
XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 1151 274.2 4.3e-73
NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo ( 435) 1151 274.2 4.5e-73
NP_000615 (OMIM: 601841) plasma serine protease in ( 406) 1139 271.4 2.9e-72
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin ( 423) 1107 264.1 4.9e-70
NP_001271204 (OMIM: 615677) serpin A9 isoform C [H ( 399) 1092 260.6 5.1e-69
NP_000345 (OMIM: 300932,314200) thyroxine-binding ( 415) 1092 260.6 5.3e-69
NP_001747 (OMIM: 122500,611489) corticosteroid-bin ( 405) 1077 257.2 5.6e-68
NP_001002235 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121177 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121173 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121178 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121176 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_000286 (OMIM: 107400,606963,613490) alpha-1-ant ( 418) 1064 254.2 4.6e-67
XP_016876859 (OMIM: 107400,606963,613490) PREDICTE ( 418) 1064 254.2 4.6e-67
NP_001121175 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121179 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001002236 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121172 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
NP_001121174 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1064 254.2 4.6e-67
XP_006724746 (OMIM: 300932,314200) PREDICTED: thyr ( 425) 1064 254.2 4.7e-67
XP_011535018 (OMIM: 615677) PREDICTED: serpin A9 i ( 337) 1006 240.8 4e-63
XP_011535019 (OMIM: 615677) PREDICTED: serpin A9 i ( 337) 1006 240.8 4e-63
XP_005262237 (OMIM: 300932,314200) PREDICTED: thyr ( 371) 945 226.8 7.3e-59
NP_006211 (OMIM: 107410) putative alpha-1-antitryp ( 421) 912 219.2 1.6e-56
NP_001271205 (OMIM: 615677) serpin A9 isoform D [H ( 286) 807 195.0 2.1e-49
NP_001035983 (OMIM: 615677) serpin A9 isoform B [H ( 335) 722 175.5 1.8e-43
XP_005245255 (OMIM: 107300,613118) PREDICTED: anti ( 416) 632 154.8 3.8e-37
NP_000479 (OMIM: 107300,613118) antithrombin-III p ( 464) 632 154.8 4.1e-37
XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 627 153.6 7.7e-37
XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 627 153.6 7.7e-37
NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 627 153.6 7.7e-37
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 597 146.7 9.2e-35
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 597 146.7 9.2e-35
NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 597 146.7 9.2e-35
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 597 146.7 9.2e-35
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 597 146.7 9.2e-35
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 597 146.7 9.2e-35
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 597 146.7 9.2e-35
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 597 146.7 9.3e-35
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 597 146.7 9.3e-35
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 597 146.8 9.5e-35
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 597 146.8 9.6e-35
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 597 146.8 1.1e-34
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 596 146.5 1.1e-34
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 596 146.5 1.1e-34
NP_001094077 (OMIM: 605271) protein Z-dependent pr ( 444) 592 145.6 2.3e-34
>>NP_001275962 (OMIM: 147935) kallistatin isoform 2 prec (427 aa)
initn: 2798 init1: 2798 opt: 2798 Z-score: 3480.5 bits: 653.1 E(85289): 4e-187
Smith-Waterman score: 2798; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB6 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK
370 380 390 400 410 420
pF1KB6 VVDPTKP
:::::::
NP_001 VVDPTKP
>>NP_006206 (OMIM: 147935) kallistatin isoform 2 precurs (427 aa)
initn: 2798 init1: 2798 opt: 2798 Z-score: 3480.5 bits: 653.1 E(85289): 4e-187
Smith-Waterman score: 2798; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB6 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK
370 380 390 400 410 420
pF1KB6 VVDPTKP
:::::::
NP_006 VVDPTKP
>>NP_001275961 (OMIM: 147935) kallistatin isoform 1 [Hom (464 aa)
initn: 2798 init1: 2798 opt: 2798 Z-score: 3479.9 bits: 653.1 E(85289): 4.3e-187
Smith-Waterman score: 2798; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:38-464)
10 20 30
pF1KB6 MHLIDYLLLLLVGLLALSHGQLHVEHDGES
::::::::::::::::::::::::::::::
NP_001 PPPGTHSWYRAALTEGQGLLAANPGLRVQRMHLIDYLLLLLVGLLALSHGQLHVEHDGES
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 CSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 LGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 FLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 NYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 KGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 QILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSA
370 380 390 400 410 420
400 410 420
pF1KB6 QTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
:::::::::::::::::::::::::::::::::::::
NP_001 QTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
430 440 450 460
>>XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 isofo (417 aa)
initn: 1081 init1: 777 opt: 1151 Z-score: 1433.1 bits: 274.2 E(85289): 4.3e-73
Smith-Waterman score: 1151; 47.8% identity (78.2% similar) in 385 aa overlap (44-426:37-416)
20 30 40 50 60 70
pF1KB6 LLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGK
...:. .. :.:::::.: .. :::..
XP_011 GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB6 NIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGH
::::::.:.:.. ::::::: : ...:::.:::::::. :: .:.:::::.:.:..:..
XP_011 NIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSK
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB6 GLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGK
: ..:::::....:.. :.::... .:::..: :.: . . ::.::::.:.::
XP_011 DLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB6 IVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPK-DFYVDENTTVRVPMMLQDQEH
.::... : . :::::.:.::: ::::: : . : : :..::.:::: : .:.
XP_011 VVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQ-KEQ
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB6 HWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYK
. : : : ::.:::::::..::.::..::::..:..:. . : .:.. :.::
XP_011 FAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKR----
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB6 KLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDE
.:. .:.::::.:: :. :::..:. ..:.: ::.:::.:...:..::. :::.:::.:
XP_011 WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSE
310 320 330 340 350 360
380 390 400 410 420
pF1KB6 AGTEAAAATSFAIKFFSAQTNRHI-LRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
::::.:::. . : . .. . ::: ::..: . .:...:::::: .:::
XP_011 EGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS
370 380 390 400 410
>>XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 isofo (417 aa)
initn: 1081 init1: 777 opt: 1151 Z-score: 1433.1 bits: 274.2 E(85289): 4.3e-73
Smith-Waterman score: 1151; 47.8% identity (78.2% similar) in 385 aa overlap (44-426:37-416)
20 30 40 50 60 70
pF1KB6 LLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGK
...:. .. :.:::::.: .. :::..
XP_011 GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB6 NIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGH
::::::.:.:.. ::::::: : ...:::.:::::::. :: .:.:::::.:.:..:..
XP_011 NIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSK
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB6 GLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGK
: ..:::::....:.. :.::... .:::..: :.: . . ::.::::.:.::
XP_011 DLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB6 IVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPK-DFYVDENTTVRVPMMLQDQEH
.::... : . :::::.:.::: ::::: : . : : :..::.:::: : .:.
XP_011 VVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQ-KEQ
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB6 HWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYK
. : : : ::.:::::::..::.::..::::..:..:. . : .:.. :.::
XP_011 FAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKR----
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB6 KLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDE
.:. .:.::::.:: :. :::..:. ..:.: ::.:::.:...:..::. :::.:::.:
XP_011 WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSE
310 320 330 340 350 360
380 390 400 410 420
pF1KB6 AGTEAAAATSFAIKFFSAQTNRHI-LRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
::::.:::. . : . .. . ::: ::..: . .:...:::::: .:::
XP_011 EGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS
370 380 390 400 410
>>NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo sap (435 aa)
initn: 1081 init1: 777 opt: 1151 Z-score: 1432.9 bits: 274.2 E(85289): 4.5e-73
Smith-Waterman score: 1151; 47.8% identity (78.2% similar) in 385 aa overlap (44-426:55-434)
20 30 40 50 60 70
pF1KB6 LLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGK
...:. .. :.:::::.: .. :::..
NP_783 GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ
30 40 50 60 70 80
80 90 100 110 120 130
pF1KB6 NIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGH
::::::.:.:.. ::::::: : ...:::.:::::::. :: .:.:::::.:.:..:..
NP_783 NIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSK
90 100 110 120 130 140
140 150 160 170 180 190
pF1KB6 GLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGK
: ..:::::....:.. :.::... .:::..: :.: . . ::.::::.:.::
NP_783 DLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGK
150 160 170 180 190 200
200 210 220 230 240 250
pF1KB6 IVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPK-DFYVDENTTVRVPMMLQDQEH
.::... : . :::::.:.::: ::::: : . : : :..::.:::: : .:.
NP_783 VVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQ-KEQ
210 220 230 240 250 260
260 270 280 290 300 310
pF1KB6 HWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYK
. : : : ::.:::::::..::.::..::::..:..:. . : .:.. :.::
NP_783 FAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKR----
270 280 290 300 310
320 330 340 350 360 370
pF1KB6 KLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDE
.:. .:.::::.:: :. :::..:. ..:.: ::.:::.:...:..::. :::.:::.:
NP_783 WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSE
320 330 340 350 360 370
380 390 400 410 420
pF1KB6 AGTEAAAATSFAIKFFSAQTNRHI-LRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
::::.:::. . : . .. . ::: ::..: . .:...:::::: .:::
NP_783 EGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS
380 390 400 410 420 430
>>NP_000615 (OMIM: 601841) plasma serine protease inhibi (406 aa)
initn: 984 init1: 625 opt: 1139 Z-score: 1418.4 bits: 271.4 E(85289): 2.9e-72
Smith-Waterman score: 1139; 45.0% identity (74.8% similar) in 420 aa overlap (6-424:4-406)
10 20 30 40 50
pF1KB6 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANA-DFA
.::: :: ::. . ..:: .: : .... . :. .::.. ::.
NP_000 MQLFLLLCLV-LLSPQGASLHRHHPREM-----KKRVEDLHVGAT---VAPSSRRDFT
10 20 30 40
60 70 80 90 100 110
pF1KB6 FRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHR
: .: .:: .:...:::::.::: . ::::::: : .. :::::::.:: . ::...::
NP_000 FDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTI
:::.::. :: : :.. .:.::: . . . :.. ..: : : ::: :..:..
NP_000 GFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAM
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 QLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENT
. :::.: :.:.::::::...: .......::::.::: :: : . : .:::: .:
NP_000 KQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSET
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 TVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLM
.:::::: .....: :: :: : : :. . :.:.::..::::..:::...:. :. . :
NP_000 VVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLR
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 RWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEA
.: ....:: .:::.:::::: ::: :...:: ::....:.. ::::::........
NP_000 KWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB6 SKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLG
:. :::...:::.::.:::::. . : ::. : . : ::::::. : .. ..::::
NP_000 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN---NILFLG
350 360 370 380 390 400
420
pF1KB6 KVVDPTKP
:: :
NP_000 KVNRP
>>NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin prec (423 aa)
initn: 890 init1: 775 opt: 1107 Z-score: 1378.4 bits: 264.1 E(85289): 4.9e-70
Smith-Waterman score: 1107; 44.8% identity (73.6% similar) in 424 aa overlap (7-426:5-422)
10 20 30 40 50 60
pF1KB6 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
: :: .:::: . . : . .. . : . .: .: ::.::::
NP_001 MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAF
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
.: .. ..: ::..:::::::.: :.::::: . . ..::.:: ::::: ::...:..
NP_001 SLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
:::::.::: . :. .:.:.:....:..: .: .:. .: .. : :.: :.... .
NP_001 FQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT
::::.::. :::::.::...: ....:::::::.::: :: :: . : . ::....
NP_001 LINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKW
180 190 200 210 220 230
250 260 270 280 290
pF1KB6 VRVPMMLQDQEHHW---YLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEM
: :::: . :: :..:. : :.:... : :.:...::::.: ::.:.: .: ::
NP_001 VMVPMM---SLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPET
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 LMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKL
: :: . :. : . ::.::::::: .: :..:: .::. . :.. ::::::: ..:
NP_001 LKRWRDSLE---FREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB6 EASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTN-RHILRFNRPFLVVIFSTSTQSVL
.:. :::.::: : ::::.:::. : ..:: .. : :.:::::::..: :.::...
NP_001 AVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIF
360 370 380 390 400 410
420
pF1KB6 FLGKVVDPTKP
:..::..: .
NP_001 FMSKVTNPKQA
420
>>NP_001271204 (OMIM: 615677) serpin A9 isoform C [Homo (399 aa)
initn: 1034 init1: 730 opt: 1092 Z-score: 1360.1 bits: 260.6 E(85289): 5.1e-69
Smith-Waterman score: 1092; 48.8% identity (78.7% similar) in 361 aa overlap (69-426:44-398)
40 50 60 70 80 90
pF1KB6 ILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSR
:::..::::::.:.:.. ::::::: : ..
NP_001 RELQPSKQVSGLTNHARTGQEKRNLQRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTK
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB6 SQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLND
.:::.:::::::. :: .:.:::::.:.:..:.. : ..:::::....:.. :.::..
NP_001 TQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGN
80 90 100 110 120 130
160 170 180 190 200 210
pF1KB6 TMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKAL
. .:::..: :.: . . ::.::::.:.::.::... : . :::::.:.:::
NP_001 VKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAK
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB6 WEKPFISSRTTPK-DFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVF
::::: : . : : :..::.:::: : .:. . : : : ::.:::::::..:
NP_001 WEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQ-KEQFAFGVDTELNCFVLQMDYKGDAVAF
200 210 220 230 240 250
280 290 300 310 320 330
pF1KB6 FILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLG
:.::..::::..:..:. . : .:.. :.:: .:. .:.::::.:: :. :::..:
NP_001 FVLPSKGKMRQLEQALSARTLRKWSHSLQKR----WIEVFIPRFSISASYNLETILPKMG
260 270 280 290 300
340 350 360 370 380 390
pF1KB6 FTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATS--FAIKFFSAQTNRH
. ..:.: ::.:::.:...:..::. :::.:::.: ::::.:::. : .. .. .
NP_001 IQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPS-YF
310 320 330 340 350 360
400 410 420
pF1KB6 ILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
. ::: ::..: . .:...:::::: .:::
NP_001 TVSFNRTFLMMITNKATDGILFLGKVENPTKS
370 380 390
>>NP_000345 (OMIM: 300932,314200) thyroxine-binding glob (415 aa)
initn: 1064 init1: 800 opt: 1092 Z-score: 1359.8 bits: 260.6 E(85289): 5.3e-69
Smith-Waterman score: 1106; 43.7% identity (73.3% similar) in 423 aa overlap (6-426:6-414)
10 20 30 40 50 60
pF1KB6 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
::.::..:: : : : .: .:. . : :.. ::::::
NP_000 MSPFLYLVLLVLGLHATIHCA-SPEGKVTACHSSQPNATL--------YKMSSINADFAF
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
.: .. ::: :::::::.::::: .:::.::: ....:.: ::::::. ....:
NP_000 NLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
::::. .::.: . :: ..:.:::....:: :::::::. ..::...: :.: . .. :
NP_000 FQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQ
120 130 140 150 160 170
190 200 210 220 230
pF1KB6 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKD-FYVDENT
::.::. .:.::.: :...:: ...:::::::.::: : .:: :.: .. : .:..:
NP_000 EINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 TVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLM
::.:::: : .:....: : : :.::.:::. .: ..:.::..:.:. .: ... . :
NP_000 TVQVPMMHQ-MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 RWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEA
.:: ::.: ..: .::::::..: : : ..:. .:. ::.::.:... :.
NP_000 KWNRLLQK----GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKL
300 310 320 330 340
360 370 380 390 400 410
pF1KB6 SKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRH-ILRFNRPFLVVIFSTSTQSVLFL
:.. :::.: . : ::::::. .. .: : :....: :...:. ::.:.:::
NP_000 SNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFL
350 360 370 380 390 400
420
pF1KB6 GKVVDPTKP
::::.::.
NP_000 GKVVNPTEA
410
427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:23:17 2016 done: Sat Nov 5 11:23:18 2016
Total Scan time: 7.780 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]