Result of FASTA (omim) for
pFN21AE4442
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4442, 459 aa
1>>>pF1KE4442 459 - 459 aa - 459 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8893+/-0.000333; mu= 1.7114+/- 0.021
mean_var=220.7442+/-43.877, 0's: 0 Z-trim(122.3): 73 B-trim: 7 in 2/55
Lambda= 0.086324
statistics sampled from 40116 (40196) to 40116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.471), width: 16
Scan time: 11.860
The best scores are: opt bits E(85289)
NP_001207 (OMIM: 603179) carbonic anhydrase 9 prec ( 459) 3145 404.3 3.6e-112
XP_005245116 (OMIM: 604832) PREDICTED: carbonic an ( 336) 729 103.3 1.1e-21
NP_036245 (OMIM: 604832) carbonic anhydrase 14 pre ( 337) 725 102.8 1.5e-21
XP_006711322 (OMIM: 604832) PREDICTED: carbonic an ( 318) 711 101.0 4.8e-21
XP_005245117 (OMIM: 604832) PREDICTED: carbonic an ( 319) 707 100.5 6.8e-21
NP_001209 (OMIM: 143860,603263) carbonic anhydrase ( 354) 692 98.7 2.7e-20
XP_011540385 (OMIM: 114780) PREDICTED: carbonic an ( 294) 668 95.6 1.9e-19
NP_001206 (OMIM: 114780) carbonic anhydrase 6 isof ( 308) 666 95.4 2.3e-19
NP_001257429 (OMIM: 114780) carbonic anhydrase 6 i ( 313) 666 95.4 2.3e-19
XP_011540386 (OMIM: 114780) PREDICTED: carbonic an ( 324) 666 95.4 2.4e-19
NP_996808 (OMIM: 143860,603263) carbonic anhydrase ( 343) 650 93.5 9.9e-19
XP_011507681 (OMIM: 604832) PREDICTED: carbonic an ( 323) 622 89.9 1.1e-17
XP_006711324 (OMIM: 604832) PREDICTED: carbonic an ( 281) 616 89.2 1.6e-17
XP_016856382 (OMIM: 604832) PREDICTED: carbonic an ( 263) 598 86.9 7.2e-17
NP_005173 (OMIM: 114770) carbonic anhydrase 7 isof ( 264) 547 80.5 5.9e-15
NP_001257430 (OMIM: 114780) carbonic anhydrase 6 i ( 248) 530 78.4 2.4e-14
NP_000058 (OMIM: 259730,611492) carbonic anhydrase ( 260) 500 74.7 3.4e-13
NP_940986 (OMIM: 611436) carbonic anhydrase 13 [Ho ( 262) 494 73.9 5.7e-13
NP_001308767 (OMIM: 114815,613227) carbonic anhydr ( 263) 486 72.9 1.1e-12
NP_001158302 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 483 72.6 1.5e-12
NP_001122303 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 483 72.6 1.5e-12
NP_001122302 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 483 72.6 1.5e-12
NP_001729 (OMIM: 114800) carbonic anhydrase 1 isof ( 261) 483 72.6 1.5e-12
NP_001122301 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 483 72.6 1.5e-12
NP_001280571 (OMIM: 143860,603263) carbonic anhydr ( 283) 482 72.5 1.7e-12
NP_001308766 (OMIM: 114815,613227) carbonic anhydr ( 290) 475 71.6 3.2e-12
NP_004047 (OMIM: 114815,613227) carbonic anhydrase ( 290) 475 71.6 3.2e-12
XP_016884736 (OMIM: 300230) PREDICTED: carbonic an ( 278) 460 69.7 1.1e-11
XP_011521613 (OMIM: 114770) PREDICTED: carbonic an ( 242) 456 69.2 1.4e-11
NP_005172 (OMIM: 114750) carbonic anhydrase 3 [Hom ( 260) 456 69.2 1.5e-11
XP_005274499 (OMIM: 300230) PREDICTED: carbonic an ( 317) 457 69.4 1.6e-11
NP_009151 (OMIM: 300230) carbonic anhydrase 5B, mi ( 317) 457 69.4 1.6e-11
XP_005256193 (OMIM: 114770) PREDICTED: carbonic an ( 208) 453 68.8 1.6e-11
NP_001014435 (OMIM: 114770) carbonic anhydrase 7 i ( 208) 453 68.8 1.6e-11
XP_011521614 (OMIM: 114770) PREDICTED: carbonic an ( 208) 453 68.8 1.6e-11
NP_001730 (OMIM: 114761,615751) carbonic anhydrase ( 305) 441 67.4 6.2e-11
XP_005265410 (OMIM: 176886) PREDICTED: receptor-ty (1416) 451 69.1 8.5e-11
NP_002832 (OMIM: 176886) receptor-type tyrosine-pr (1445) 451 69.2 8.6e-11
NP_001278896 (OMIM: 114800) carbonic anhydrase 1 i ( 195) 406 62.9 9e-10
NP_001193768 (OMIM: 176891,600263) receptor-type t (1448) 419 65.2 1.4e-09
NP_001193767 (OMIM: 176891,600263) receptor-type t (1455) 419 65.2 1.4e-09
XP_016867966 (OMIM: 176891,600263) PREDICTED: rece (2301) 419 65.3 1.9e-09
XP_005250576 (OMIM: 176891,600263) PREDICTED: rece (2308) 419 65.3 2e-09
NP_002842 (OMIM: 176891,600263) receptor-type tyro (2315) 419 65.3 2e-09
NP_001257431 (OMIM: 114780) carbonic anhydrase 6 i ( 180) 390 60.9 3.4e-09
XP_016856384 (OMIM: 604832) PREDICTED: carbonic an ( 244) 392 61.2 3.6e-09
NP_000708 (OMIM: 114760,600852) carbonic anhydrase ( 312) 394 61.5 3.6e-09
XP_016856383 (OMIM: 604832) PREDICTED: carbonic an ( 262) 392 61.2 3.8e-09
XP_016879135 (OMIM: 114761,615751) PREDICTED: carb ( 314) 393 61.4 4e-09
XP_016884737 (OMIM: 300230) PREDICTED: carbonic an ( 248) 371 58.6 2.2e-08
>>NP_001207 (OMIM: 603179) carbonic anhydrase 9 precurso (459 aa)
initn: 3145 init1: 3145 opt: 3145 Z-score: 2134.8 bits: 404.3 E(85289): 3.6e-112
Smith-Waterman score: 3145; 99.8% identity (100.0% similar) in 459 aa overlap (1-459:1-459)
10 20 30 40 50 60
pF1KE4 MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLMPVHPQRLPRMQEDSPLGGGSSGEDDPL
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLVPVHPQRLPRMQEDSPLGGGSSGEDDPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GEEDLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEEDLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVF
370 380 390 400 410 420
430 440 450
pF1KE4 GLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA
:::::::::::::::::::::::::::::::::::::::
NP_001 GLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA
430 440 450
>>XP_005245116 (OMIM: 604832) PREDICTED: carbonic anhydr (336 aa)
initn: 689 init1: 314 opt: 729 Z-score: 510.6 bits: 103.3 E(85289): 1.1e-21
Smith-Waterman score: 729; 42.0% identity (68.2% similar) in 314 aa overlap (136-441:17-322)
110 120 130 140 150 160
pF1KE4 GSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRY-G--GDPPWPRVSPACAGRFQS
: .:: : : :. :: : :.. ::
XP_005 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQS
10 20 30 40
170 180 190 200 210 220
pF1KE4 PVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRA
:.::. . ..: : : :. :.. : : :.::::.:::.:: : .. : :.: :
XP_005 PIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLG-GLPRKYVA
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE4 LQLHLHWGAAGRPG-SEHTVEGHRFPAEIHVVHL-STAFARVDEALGRPGGLAVLAAFLE
::::::: : :: ::: .... ::.:.:: : .. ..:: :: :::::. ..:
XP_005 AQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIE
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE4 EGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGV
: .: :::..::.:.:. .. ..:.:: ... :::.....::.:.:::::::: :.:
XP_005 VGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSV
170 180 190 200 210 220
350 360 370 380 390
pF1KE4 IWTVFNQTVMLSAKQLHTLSDTLWGPGD--SRLQL-NFRATQPLNGRVIEASFPAGVDSS
.:::: . ..: .::. :. ::.. . :.: . :.:: :::: :.. ::: : ::
XP_005 LWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQG--SS
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE4 PRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAET
..: ..:. .: ::. . ::.:: .: .. .: . :
XP_005 YTTGEMLSLG----VG-ILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
290 300 310 320 330
pF1KE4 GA
>>NP_036245 (OMIM: 604832) carbonic anhydrase 14 precurs (337 aa)
initn: 696 init1: 314 opt: 725 Z-score: 507.9 bits: 102.8 E(85289): 1.5e-21
Smith-Waterman score: 729; 39.4% identity (66.4% similar) in 330 aa overlap (136-453:17-332)
110 120 130 140 150 160
pF1KE4 GSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRY-G--GDPPWPRVSPACAGRFQS
: .:: : : :. :: : :.. ::
NP_036 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQS
10 20 30 40
170 180 190 200 210 220
pF1KE4 PVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRA
:.::. . ..: : : :. :.. : : :.::::.:::.:: : .. : :.: :
NP_036 PIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLG-GLPRKYVA
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE4 LQLHLHWGAAGRPG-SEHTVEGHRFPAEIHVVHL-STAFARVDEALGRPGGLAVLAAFLE
::::::: : :: ::: .... ::.:.:: : .. ..:: :: :::::. ..:
NP_036 AQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIE
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE4 EGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGV
: .: :::..::.:.:. .. ..:.:: ... :::.....::.:.:::::::: :.:
NP_036 VGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSV
170 180 190 200 210 220
350 360 370 380 390
pF1KE4 IWTVFNQTVMLSAKQLHTLSDTLWGPGD--SRLQL-NFRATQPLNGRVIEASFPAGVDSS
.:::: . ..: .::. :. ::.. . :.: . :.:: :::: :.. :::
NP_036 LWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASF-------
230 240 250 260 270
400 410 420 430 440 450
pF1KE4 PRAAEPVQLNSCLAAGDILALVFGLLFA----VTSVAFLVQMRRQHRRGTKGGVSYRPAE
.: .: ..:..:.: :.: . . .: :... :..: .. .: . :.
NP_036 ------IQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQ
280 290 300 310 320 330
pF1KE4 VAETGA
NP_036 ATTEA
>>XP_006711322 (OMIM: 604832) PREDICTED: carbonic anhydr (318 aa)
initn: 689 init1: 314 opt: 711 Z-score: 498.8 bits: 101.0 E(85289): 4.8e-21
Smith-Waterman score: 711; 44.4% identity (69.9% similar) in 266 aa overlap (136-393:17-281)
110 120 130 140 150 160
pF1KE4 GSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRY-G--GDPPWPRVSPACAGRFQS
: .:: : : :. :: : :.. ::
XP_006 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQS
10 20 30 40
170 180 190 200 210 220
pF1KE4 PVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRA
:.::. . ..: : : :. :.. : : :.::::.:::.:: : .. : :.: :
XP_006 PIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLG-GLPRKYVA
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE4 LQLHLHWGAAGRPG-SEHTVEGHRFPAEIHVVHL-STAFARVDEALGRPGGLAVLAAFLE
::::::: : :: ::: .... ::.:.:: : .. ..:: :: :::::. ..:
XP_006 AQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIE
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE4 EGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGV
: .: :::..::.:.:. .. ..:.:: ... :::.....::.:.:::::::: :.:
XP_006 VGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSV
170 180 190 200 210 220
350 360 370 380 390
pF1KE4 IWTVFNQTVMLSAKQLHTLSDTLWGPGD--SRLQL-NFRATQPLNGRVIEASFPAGVDSS
.:::: . ..: .::. :. ::.. . :.: . :.:: :::: :.. ::: :
XP_006 LWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQGSSYT
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE4 PRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAET
XP_006 TGRRGWKTERVWSSPQHKPRLRHKFLLRYHGCG
290 300 310
>>XP_005245117 (OMIM: 604832) PREDICTED: carbonic anhydr (319 aa)
initn: 696 init1: 314 opt: 707 Z-score: 496.1 bits: 100.5 E(85289): 6.8e-21
Smith-Waterman score: 707; 44.5% identity (70.3% similar) in 263 aa overlap (136-390:17-278)
110 120 130 140 150 160
pF1KE4 GSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRY-G--GDPPWPRVSPACAGRFQS
: .:: : : :. :: : :.. ::
XP_005 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQS
10 20 30 40
170 180 190 200 210 220
pF1KE4 PVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRA
:.::. . ..: : : :. :.. : : :.::::.:::.:: : .. : :.: :
XP_005 PIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLG-GLPRKYVA
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE4 LQLHLHWGAAGRPG-SEHTVEGHRFPAEIHVVHL-STAFARVDEALGRPGGLAVLAAFLE
::::::: : :: ::: .... ::.:.:: : .. ..:: :: :::::. ..:
XP_005 AQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIE
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE4 EGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGV
: .: :::..::.:.:. .. ..:.:: ... :::.....::.:.:::::::: :.:
XP_005 VGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSV
170 180 190 200 210 220
350 360 370 380 390
pF1KE4 IWTVFNQTVMLSAKQLHTLSDTLWGPGD--SRLQL-NFRATQPLNGRVIEASFPAGVDSS
.:::: . ..: .::. :. ::.. . :.: . :.:: :::: :.. :::
XP_005 LWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSY
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE4 PRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAET
XP_005 TTGRRGWKTERVWSSPQHKPRLRHKFLLRYHGCG
290 300 310
>>NP_001209 (OMIM: 143860,603263) carbonic anhydrase 12 (354 aa)
initn: 510 init1: 444 opt: 692 Z-score: 485.4 bits: 98.7 E(85289): 2.7e-20
Smith-Waterman score: 692; 36.7% identity (63.6% similar) in 338 aa overlap (139-459:30-352)
110 120 130 140 150 160
pF1KE4 KLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRY---GGDPPWPRVSPACAGRFQSPVD
:.: : :. : . :.:.: .:::.:
NP_001 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPID
10 20 30 40 50
170 180 190 200 210 220
pF1KE4 IRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQL
.. .. . .: :::. :..: .. : ::::::.:.:: ... : .: : ::
NP_001 LHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQ-GLQSRYSATQL
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE4 HLHWGAAGRP-GSEHTVEGHRFPAEIHVVHL-STAFARVDEALGRPGGLAVLAAFLEEGP
::::: . : :::::: :..: ::.:.:: : . .. : .. ::::::...: :
NP_001 HLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGS
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE4 EENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWT
: .:....:.:... .:.:. :::..: ::: ..:..:.:::::::: :.::
NP_001 F-NPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWT
180 190 200 210 220 230
350 360 370 380 390
pF1KE4 VFNQTVMLSAKQLHTLSDTLW-----GPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSP
:: . :..: .:: .: .:. :. .. ::: .: .. :.. .::
NP_001 VFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS-------
240 250 260 270 280 290
400 410 420 430 440 450
pF1KE4 RAAEPVQLNSCLAAGDILALVFGLLFA-------VTSVAFLVQMRRQHRRGTKGGVSYRP
:.. : ::: :.....: .: :. :.. . :.. ..: . :: :.:
NP_001 ------QVQVCTAAGLSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKP
300 310 320 330 340
pF1KE4 AEVAETGA
: :: :
NP_001 ATKMETEAHA
350
>>XP_011540385 (OMIM: 114780) PREDICTED: carbonic anhydr (294 aa)
initn: 684 init1: 291 opt: 668 Z-score: 470.3 bits: 95.6 E(85289): 1.9e-19
Smith-Waterman score: 668; 39.0% identity (67.0% similar) in 267 aa overlap (139-398:25-290)
110 120 130 140 150 160
pF1KE4 KLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYG----GDPPWPRVSPACAGRFQSPV
: : :. . ::. :::.:. :::.
XP_011 MCSTMRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPI
10 20 30 40 50
170 180 190 200 210 220
pF1KE4 DIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQ
... . . :.:. :.. :.. :. . ::::.::..:: ..:... : : : :
XP_011 NLQRTKVRYNPSLKGLNMTGYETQA-GEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQ
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE4 LHLHWGAAGRP--GSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLE-E
.:.:::.:. ::::::.: : :::.:: .. . : : : ::::::::.: .
XP_011 MHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE4 GPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVI
. ::. : ...:.: .: :..: . :::.. .:: ....:. :.::::::::...:
XP_011 NYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVH
180 190 200 210 220 230
350 360 370 380 390 400
pF1KE4 WTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAA
: :. . : :: :. : ..: .. .. ..: ::::: ::.:..:: . :
XP_011 WFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQENCIPAGL
240 250 260 270 280 290
410 420 430 440 450
pF1KE4 EPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA
XP_011 I
>>NP_001206 (OMIM: 114780) carbonic anhydrase 6 isoform (308 aa)
initn: 684 init1: 291 opt: 666 Z-score: 468.7 bits: 95.4 E(85289): 2.3e-19
Smith-Waterman score: 666; 39.6% identity (68.1% similar) in 260 aa overlap (139-391:21-279)
110 120 130 140 150 160
pF1KE4 KLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYG----GDPPWPRVSPACAGRFQSPV
: : :. . ::. :::.:. :::.
NP_001 MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPI
10 20 30 40 50
170 180 190 200 210 220
pF1KE4 DIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQ
... . . :.:. :.. :.. :. . ::::.::..:: ..:... : : : :
NP_001 NLQRTKVRYNPSLKGLNMTGYETQA-GEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQ
60 70 80 90 100
230 240 250 260 270 280
pF1KE4 LHLHWGAAGRP--GSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLE-E
.:.:::.:. ::::::.: : :::.:: .. . : : : ::::::::.: .
NP_001 MHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE4 GPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVI
. ::. : ...:.: .: :..: . :::.. .:: ....:. :.::::::::...:
NP_001 NYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVH
170 180 190 200 210 220
350 360 370 380 390 400
pF1KE4 WTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAA
: :. . : :: :. : ..: .. .. ..: ::::: ::.:..::
NP_001 WFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEF
230 240 250 260 270 280
410 420 430 440 450
pF1KE4 EPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA
NP_001 QFYLHKIEEILDYLRRALN
290 300
>>NP_001257429 (OMIM: 114780) carbonic anhydrase 6 isofo (313 aa)
initn: 684 init1: 291 opt: 666 Z-score: 468.6 bits: 95.4 E(85289): 2.3e-19
Smith-Waterman score: 673; 37.6% identity (65.8% similar) in 295 aa overlap (139-417:21-313)
110 120 130 140 150 160
pF1KE4 KLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYG----GDPPWPRVSPACAGRFQSPV
: : :. . ::. :::.:. :::.
NP_001 MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPI
10 20 30 40 50
170 180 190 200 210 220
pF1KE4 DIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQ
... . . :.:. :.. :.. :. . ::::.::..:: ..:... : : : :
NP_001 NLQRTKVRYNPSLKGLNMTGYETQA-GEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQ
60 70 80 90 100
230 240 250 260 270 280
pF1KE4 LHLHWGAAGRP--GSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLE-E
.:.:::.:. ::::::.: : :::.:: .. . : : : ::::::::.: .
NP_001 MHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE4 GPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVI
. ::. : ...:.: .: :..: . :::.. .:: ....:. :.::::::::...:
NP_001 NYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVH
170 180 190 200 210 220
350 360 370 380 390
pF1KE4 WTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPA---------
: :. . : :: :. : ..: .. .. ..: ::::: ::.:..::
NP_001 WFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQGKGHGGHR
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE4 GVDSSPRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPA
: ...::. .:.. :: :.. :
NP_001 GRSQNPRV-QPTSTRHPLALGSLEA
290 300 310
>>XP_011540386 (OMIM: 114780) PREDICTED: carbonic anhydr (324 aa)
initn: 684 init1: 291 opt: 666 Z-score: 468.4 bits: 95.4 E(85289): 2.4e-19
Smith-Waterman score: 666; 39.6% identity (68.1% similar) in 260 aa overlap (139-391:25-283)
110 120 130 140 150 160
pF1KE4 KLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYG----GDPPWPRVSPACAGRFQSPV
: : :. . ::. :::.:. :::.
XP_011 MCSTMRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPI
10 20 30 40 50
170 180 190 200 210 220
pF1KE4 DIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQ
... . . :.:. :.. :.. :. . ::::.::..:: ..:... : : : :
XP_011 NLQRTKVRYNPSLKGLNMTGYETQA-GEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQ
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE4 LHLHWGAAGRP--GSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLE-E
.:.:::.:. ::::::.: : :::.:: .. . : : : ::::::::.: .
XP_011 MHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE4 GPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVI
. ::. : ...:.: .: :..: . :::.. .:: ....:. :.::::::::...:
XP_011 NYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVH
180 190 200 210 220 230
350 360 370 380 390 400
pF1KE4 WTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAA
: :. . : :: :. : ..: .. .. ..: ::::: ::.:..::
XP_011 WFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQENAYIPSG
240 250 260 270 280 290
410 420 430 440 450
pF1KE4 EPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA
XP_011 KGHGGHRGRSQNPRVQPTSTRHPLALGSLEA
300 310 320
459 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:36:43 2016 done: Sun Nov 6 00:36:45 2016
Total Scan time: 11.860 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]