FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9664, 464 aa
  1>>>pF1KE9664 464 - 464 aa - 464 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.3652+/-0.000622; mu= -16.9482+/- 0.038
 mean_var=421.3776+/-81.940, 0's: 0 Z-trim(113.8): 35  B-trim: 45 in 1/54
 Lambda= 0.062480
 statistics sampled from 23244 (23255) to 23244 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.273), width:  16
 Scan time:  8.260

The best scores are:                                      opt bits E(85289)
NP_663735 (OMIM: 611772) kinetochore protein Nuf2  ( 464) 2966 282.5 1.7e-75
NP_113611 (OMIM: 611772) kinetochore protein Nuf2  ( 464) 2966 282.5 1.7e-75
XP_011508338 (OMIM: 611772) PREDICTED: kinetochore ( 418) 2662 255.0 2.8e-67


>>NP_663735 (OMIM: 611772) kinetochore protein Nuf2 [Hom  (464 aa)
 initn: 2966 init1: 2966 opt: 2966  Z-score: 1476.3  bits: 282.5 E(85289): 1.7e-75
Smith-Waterman score: 2966; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)

               10        20        30        40        50        60
pF1KE9 METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 LEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 LSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 KQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 KTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 QDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 QDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 KKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQ
              370       380       390       400       410       420

              430       440       450       460    
pF1KE9 EIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST
       ::::::::::::::::::::::::::::::::::::::::::::
NP_663 EIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST
              430       440       450       460    

>>NP_113611 (OMIM: 611772) kinetochore protein Nuf2 [Hom  (464 aa)
 initn: 2966 init1: 2966 opt: 2966  Z-score: 1476.3  bits: 282.5 E(85289): 1.7e-75
Smith-Waterman score: 2966; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)

               10        20        30        40        50        60
pF1KE9 METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 LEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 LSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 KQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 KQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 KTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 KTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 QDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 QDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 KKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 KKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQ
              370       380       390       400       410       420

              430       440       450       460    
pF1KE9 EIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST
       ::::::::::::::::::::::::::::::::::::::::::::
NP_113 EIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST
              430       440       450       460    

>>XP_011508338 (OMIM: 611772) PREDICTED: kinetochore pro  (418 aa)
 initn: 2662 init1: 2662 opt: 2662  Z-score: 1328.8  bits: 255.0 E(85289): 2.8e-67
Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 418 aa overlap (47-464:1-418)

         20        30        40        50        60        70      
pF1KE9 HIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIRLEHFYMMPVNSEVMYP
                                     ::::::::::::::::::::::::::::::
XP_011                               MIYMRALQIVYGIRLEHFYMMPVNSEVMYP
                                             10        20        30

         80        90       100       110       120       130      
pF1KE9 HLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRE
               40        50        60        70        80        90

        140       150       160       170       180       190      
pF1KE9 TYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQ
              100       110       120       130       140       150

        200       210       220       230       240       250      
pF1KE9 DFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKE
              160       170       180       190       200       210

        260       270       280       290       300       310      
pF1KE9 KMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKE
              220       230       240       250       260       270

        320       330       340       350       360       370      
pF1KE9 SLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIED
              280       290       300       310       320       330

        380       390       400       410       420       430      
pF1KE9 CNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDG
              340       350       360       370       380       390

        440       450       460    
pF1KE9 IEKAAEDSYAKIDEKTAELKRKMFKMST
       ::::::::::::::::::::::::::::
XP_011 IEKAAEDSYAKIDEKTAELKRKMFKMST
              400       410        




464 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 23:11:03 2016 done: Sun Nov  6 23:11:04 2016
 Total Scan time:  8.260 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]