Result of FASTA (omim) for
pFN21AE1369
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1369, 538 aa
1>>>pF1KE1369 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0685+/-0.000404; mu= -5.4510+/- 0.025
mean_var=411.7865+/-84.727, 0's: 0 Z-trim(124.3): 299 B-trim: 0 in 0/55
Lambda= 0.063203
statistics sampled from 45368 (45729) to 45368 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.536), width: 16
Scan time: 9.740
The best scores are: opt bits E(85289)
NP_116265 (OMIM: 609066) LIM domain-containing pro ( 538) 3872 367.1 7.7e-101
NP_001276026 (OMIM: 609066) LIM domain-containing ( 369) 2336 226.9 8.6e-59
NP_001073905 (OMIM: 614790) Wilms tumor protein 1- ( 430) 1149 118.7 3.7e-26
NP_055055 (OMIM: 604543) LIM domain-containing pro ( 676) 1123 116.5 2.6e-25
XP_011524754 (OMIM: 614790) PREDICTED: Wilms tumor ( 472) 999 105.1 5.1e-22
XP_006723077 (OMIM: 614790) PREDICTED: Wilms tumor ( 384) 991 104.2 7.3e-22
NP_932352 (OMIM: 609066) LIM domain-containing pro ( 121) 945 99.5 6e-21
XP_016861871 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 851 91.5 5.7e-18
XP_011511138 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 851 91.5 5.7e-18
XP_016861867 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_011511130 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_005247510 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_016861866 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_011511129 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_011511133 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_011511135 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_005247507 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_005247503 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_011511122 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_016861868 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_016861869 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_005247508 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
XP_011511136 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 851 91.7 7.1e-18
NP_001161143 (OMIM: 600700) lipoma-preferred partn ( 612) 851 91.7 7.1e-18
NP_005569 (OMIM: 600700) lipoma-preferred partner ( 612) 851 91.7 7.1e-18
XP_011511125 (OMIM: 600700) PREDICTED: lipoma-pref ( 637) 851 91.7 7.3e-18
XP_011524755 (OMIM: 614790) PREDICTED: Wilms tumor ( 231) 818 88.2 2.9e-17
NP_003293 (OMIM: 602933) thyroid receptor-interact ( 476) 812 88.0 7e-17
NP_001161144 (OMIM: 600700) lipoma-preferred partn ( 465) 797 86.6 1.8e-16
XP_011514871 (OMIM: 602002) PREDICTED: zyxin isofo ( 541) 744 81.9 5.6e-15
NP_001010972 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 686 76.6 2.3e-13
NP_003452 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 686 76.6 2.3e-13
XP_016868076 (OMIM: 602002) PREDICTED: zyxin isofo ( 631) 686 76.6 2.4e-13
NP_001019387 (OMIM: 607747) filamin-binding LIM pr ( 276) 620 70.3 8.9e-12
XP_011539919 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 616 70.0 1.4e-11
XP_005245966 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 616 70.0 1.4e-11
NP_060026 (OMIM: 607747) filamin-binding LIM prote ( 373) 616 70.0 1.4e-11
XP_016857014 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 616 70.0 1.4e-11
XP_011539920 (OMIM: 607747) PREDICTED: filamin-bin ( 314) 373 47.8 5.9e-05
XP_016857015 (OMIM: 607747) PREDICTED: filamin-bin ( 309) 372 47.7 6.2e-05
XP_006710767 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_016857008 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_005245958 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_016857013 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_005245960 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_016857012 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_016857009 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_006710768 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_016857010 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
XP_016857011 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 369 47.5 8.5e-05
>>NP_116265 (OMIM: 609066) LIM domain-containing protein (538 aa)
initn: 3872 init1: 3872 opt: 3872 Z-score: 1931.3 bits: 367.1 E(85289): 7.7e-101
Smith-Waterman score: 3872; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KE1 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIV
430 440 450 460 470 480
490 500 510 520 530
pF1KE1 RVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
490 500 510 520 530
>>NP_001276026 (OMIM: 609066) LIM domain-containing prot (369 aa)
initn: 2335 init1: 2335 opt: 2336 Z-score: 1176.5 bits: 226.9 E(85289): 8.6e-59
Smith-Waterman score: 2336; 96.0% identity (97.2% similar) in 354 aa overlap (1-354:1-351)
10 20 30 40 50 60
pF1KE1 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYH
:::::::::::::::::::::::::::::::::::: . . ..: :::
NP_001 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGIMLTWSP-LHGA--LCQARSFSPS
310 320 330 340 350
370 380 390 400 410 420
pF1KE1 TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK
NP_001 LEVCSGEKSFYN
360
>>NP_001073905 (OMIM: 614790) Wilms tumor protein 1-inte (430 aa)
initn: 1252 init1: 1095 opt: 1149 Z-score: 590.7 bits: 118.7 E(85289): 3.7e-26
Smith-Waterman score: 1199; 44.2% identity (58.4% similar) in 498 aa overlap (40-535:26-422)
10 20 30 40 50 60
pF1KE1 RLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDE--PLEPAREQ
: :.: . : :: ::::: : : .
NP_001 MQRSRAGADEAALLLAGLALRELEPGCGSPGR-GRRGPRPGPGDEAAPALGRRGK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 GSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSPRSSFASS
:: : . : .. : :: : .:. . :: :::.:.:.:
NP_001 GSGGPEAGADGLSRGER-------GP---RRAAVPEL--------SAQPAGSPRASLAGS
60 70 80 90
130 140 150 160 170 180
pF1KE1 SASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGPP
::.:.:: : :.::::.::::::::: .: . :
NP_001 -----------------DGGGGGG-------SARSSGISLGYDQRHGSPR-SGR---SDP
100 110 120
190 200 210 220 230 240
pF1KE1 LAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALAGAGVG
: :: : . : .: : . :: :: :
NP_001 RPG------PG--------------------PPSVGSARSSVSSLGSRGSAGAYADFLPP
130 140 150 160
250 260 270 280 290 300
pF1KE1 AAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPS
.: : :. .:. : . . : : : :::.: ::
NP_001 GACPAPARSPEPA-----GPAPFPLPA---------LPLP---PGREGG---------PS
170 180 190
310 320 330 340 350 360
pF1KE1 GLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCC
. :. .. : :: : .. .:::: ::::. :::: ..::::. :::::.::.:
NP_001 AAERRLEALTRELERA--LEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCD
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE1 SCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCF
:::: :: ::::.:. .:::.::.:.::::..:.:: ::::::.: ::::.:::::::::
NP_001 SCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCF
260 270 280 290 300 310
430 440 450 460 470 480
pF1KE1 RCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDR
:: :::.::::.::::: :..::: ::: .:::::.:..::::..::: .::.::::
NP_001 RCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDR
320 330 340 350 360 370
490 500 510 520 530
pF1KE1 DYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
::: ::::::: .::: ::: :.:: :::::. ::..::. :.
NP_001 DYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQPGPLPSPTVHVTEL
380 390 400 410 420 430
>>NP_055055 (OMIM: 604543) LIM domain-containing protein (676 aa)
initn: 1211 init1: 1094 opt: 1123 Z-score: 575.4 bits: 116.5 E(85289): 2.6e-25
Smith-Waterman score: 1189; 39.8% identity (64.9% similar) in 490 aa overlap (79-531:184-665)
50 60 70 80 90 100
pF1KE1 PRGATGGPGDEPLEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPD
:. .:.. :. : : :. .: . .. : .
NP_055 LATSEMSAFHQPGPCEDPSCLTHGDYYDNLSLASPKW-GDKP-GVSPSIGLSVGSGWPSS
160 170 180 190 200 210
110 120 130 140 150 160
pF1KE1 FRLEPTAPALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPC----SNRTSG
.: : . . : .:. :: .::: ...: :: .. .: . ..
NP_055 PGSDPPLPKPCGDHPLNHRQLSLSSSRSS-EGSLGGQNSGIGGRSSEKPTGLWSTASSQR
220 230 240 250 260 270
170 180 190 200 210
pF1KE1 ISMGY---DQRHGSPLPAGPCLFGPPLAGAPAGYS-P--GGVPSAYPELHAALDRLYAQR
.: : . ..:.: .:: : ..:: . : : ::.: . : . .. ... .
NP_055 VSPGLPSPNLENGAP-AVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMS-K
280 290 300 310 320
220 230 240 250 260 270
pF1KE1 PAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQD
: . : .. : . : .: ... .: : ..:: :: : : ..: . .
NP_055 P-NVDPQPWFQDGPKSYLSSSAPSSSPAGLDG--SQQGAVPGLGPKPGCTDLGTGPKLSP
330 340 350 360 370 380
280 290 300 310 320
pF1KE1 E------LTALLRLTVGTGGREAGARGEPSGI---EPSG--LEEP-----PGPFV-PEAA
...: .:. : .. : ... ::. .. : ::: . : ::
NP_055 TSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAA
390 400 410 420 430 440
330 340 350 360 370
pF1KE1 RARM--------REPEA--REDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR
. .. :: .: . ::::.:.::.::..: ..::::. .::: ::.: .:.:
NP_055 ELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSR
450 460 470 480 490 500
380 390 400 410 420 430
pF1KE1 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV
:: :::: :::.:.::::.:.::::..:..: .:::::.. ::::.:::::::::::..
NP_055 KLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVI
510 520 530 540 550 560
440 450 460 470 480 490
pF1KE1 CNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHF
::.::::.::::: :..::: :::: :::::::: :::: :: .. .::.:::::::
NP_055 CNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHV
570 580 590 600 610 620
500 510 520 530
pF1KE1 ECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
:::::::: ..:.::.: :.::. ::.::.::..::. :
NP_055 ECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKRPSSTALHQHHF
630 640 650 660 670
>>XP_011524754 (OMIM: 614790) PREDICTED: Wilms tumor pro (472 aa)
initn: 1104 init1: 947 opt: 999 Z-score: 516.3 bits: 105.1 E(85289): 5.1e-22
Smith-Waterman score: 1049; 43.4% identity (57.3% similar) in 461 aa overlap (40-498:26-385)
10 20 30 40 50 60
pF1KE1 RLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDE--PLEPAREQ
: :.: . : :: ::::: : : .
XP_011 MQRSRAGADEAALLLAGLALRELEPGCGSPGR-GRRGPRPGPGDEAAPALGRRGK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 GSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSPRSSFASS
:: : . : .. : :: : .:. . :: :::.:.:.:
XP_011 GSGGPEAGADGLSRGER-------GP---RRAAVPEL--------SAQPAGSPRASLAGS
60 70 80 90
130 140 150 160 170 180
pF1KE1 SASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGPP
::.:.:: : :.::::.::::::::: .: . :
XP_011 -----------------DGGGGGG-------SARSSGISLGYDQRHGSPR-SGR---SDP
100 110 120
190 200 210 220 230 240
pF1KE1 LAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALAGAGVG
: :: : . : .: : . :: :: :
XP_011 RPG------PG--------------------PPSVGSARSSVSSLGSRGSAGAYADFLPP
130 140 150 160
250 260 270 280 290 300
pF1KE1 AAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPS
.: : :. .:. : . . : : : :::.: ::
XP_011 GACPAPARSPEPA-----GPAPFPLPA---------LPL---PPGREGG---------PS
170 180 190
310 320 330 340 350 360
pF1KE1 GLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCC
. :. .. : :: : .. .:::: ::::. :::: ..::::. :::::.::.:
XP_011 AAERRLEALTRELERA--LEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCD
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE1 SCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCF
:::: :: ::::.:. .:::.::.:.::::..:.:: ::::::.: ::::.:::::::::
XP_011 SCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCF
260 270 280 290 300 310
430 440 450 460 470 480
pF1KE1 RCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDR
:: :::.::::.::::: :..::: ::: .:::::.:..::::..::: .::.::::
XP_011 RCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDR
320 330 340 350 360 370
490 500 510 520 530
pF1KE1 DYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
::: ::::::
XP_011 DYHVACYHCEDPGDEARMADSNPLAASLPCMEQLSLGCRSSCVPPLPPGLSPCLLGLEVP
380 390 400 410 420 430
>>XP_006723077 (OMIM: 614790) PREDICTED: Wilms tumor pro (384 aa)
initn: 1096 init1: 939 opt: 991 Z-score: 513.4 bits: 104.2 E(85289): 7.3e-22
Smith-Waterman score: 1041; 43.3% identity (57.2% similar) in 460 aa overlap (40-497:26-384)
10 20 30 40 50 60
pF1KE1 RLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDE--PLEPAREQ
: :.: . : :: ::::: : : .
XP_006 MQRSRAGADEAALLLAGLALRELEPGCGSPGR-GRRGPRPGPGDEAAPALGRRGK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 GSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSPRSSFASS
:: : . : .. : :: : .:. . :: :::.:.:.:
XP_006 GSGGPEAGADGLSRGER-------GP---RRAAVPEL--------SAQPAGSPRASLAGS
60 70 80 90
130 140 150 160 170 180
pF1KE1 SASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGPP
::.:.:: : :.::::.::::::::: .: . :
XP_006 -----------------DGGGGGG-------SARSSGISLGYDQRHGSPR-SGR---SDP
100 110 120
190 200 210 220 230 240
pF1KE1 LAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALAGAGVG
: :: : . : .: : . :: :: :
XP_006 RPG------PG--------------------PPSVGSARSSVSSLGSRGSAGAYADFLPP
130 140 150 160
250 260 270 280 290 300
pF1KE1 AAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPS
.: : :. .:. : . . : : : :::.: ::
XP_006 GACPAPARSPEPA-----GPAPFPLPA---------LPL---PPGREGG---------PS
170 180 190
310 320 330 340 350 360
pF1KE1 GLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCC
. :. .. : :: : .. .:::: ::::. :::: ..::::. :::::.::.:
XP_006 AAERRLEALTRELERA--LEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCD
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE1 SCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCF
:::: :: ::::.:. .:::.::.:.::::..:.:: ::::::.: ::::.:::::::::
XP_006 SCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCF
260 270 280 290 300 310
430 440 450 460 470 480
pF1KE1 RCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDR
:: :::.::::.::::: :..::: ::: .:::::.:..::::..::: .::.::::
XP_006 RCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDR
320 330 340 350 360 370
490 500 510 520 530
pF1KE1 DYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
::: :::::
XP_006 DYHVACYHCE
380
>>NP_932352 (OMIM: 609066) LIM domain-containing protein (121 aa)
initn: 945 init1: 945 opt: 945 Z-score: 497.1 bits: 99.5 E(85289): 6e-21
Smith-Waterman score: 945; 100.0% identity (100.0% similar) in 121 aa overlap (418-538:1-121)
390 400 410 420 430 440
pF1KE1 EEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSN
::::::::::::::::::::::::::::::
NP_932 MGKSYHPGCFRCIVCNKCLDGIPFTVDFSN
10 20 30
450 460 470 480 490 500
pF1KE1 QVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 QVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEE
40 50 60 70 80 90
510 520 530
pF1KE1 GCCCFPLDGHLLCHGCHMQRLNARQPPANYI
:::::::::::::::::::::::::::::::
NP_932 GCCCFPLDGHLLCHGCHMQRLNARQPPANYI
100 110 120
>>XP_016861871 (OMIM: 600700) PREDICTED: lipoma-preferre (449 aa)
initn: 778 init1: 551 opt: 851 Z-score: 443.6 bits: 91.5 E(85289): 5.7e-18
Smith-Waterman score: 881; 33.0% identity (58.7% similar) in 460 aa overlap (90-528:4-438)
60 70 80 90 100 110
pF1KE1 PLEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPT-------RALPLPQSLPPDFRLE
: :: : . : ::. :
XP_016 MVIPNQPPLTATKKSTLKPQPAPQAGPI-----
10 20
120 130 140 150 160
pF1KE1 PTAP--ALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGIS-MGY
:.:: .:.:. . . .: . :: : : .. . .: . . : :.. : . .::
XP_016 PVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGY
30 40 50 60 70 80
170 180 190 200 210 220
pF1KE1 DQRHGSPLP-AGPCLFGPPLAGAPAGYS----PGGVPS-AY---PELHAALDRLYAQRPA
. . :.: .: : :: . . :. :: : .: :. . :: :
XP_016 NTQ---PVPVSGQC--PPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGP-
90 100 110 120 130 140
230 240 250 260 270
pF1KE1 GFGCQESRHSYPPALGSPG--ALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQD
:.: .:.. :. :. : : . : :: . ::: . :
XP_016 GYG---GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYI----TD
150 160 170 180 190
280 290 300 310 320 330
pF1KE1 ELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTC
..: . : ..: : ::.. :: : . . :..: : ..::: :
XP_016 PVSAPCAPPLQPKGGHSGQLG-PSSVAPSFRPEDELEHLTKKMLYDMENPPA-DEYFGRC
200 210 220 230 240 250
340 350 360 370 380 390
pF1KE1 IKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQE
.:.... :....: :.:...:..::.: :. :: . ::.:. ..::: :. .
XP_016 ARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYI-----N
260 270 280 290 300
400 410 420 430 440 450
pF1KE1 AAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKN
. :.: ::.. :.:.::.: ::.::: :: :..:.. ::::::::: .. ..:. :.::.
XP_016 TLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKK
310 320 330 340 350 360
460 470 480 490 500 510
pF1KE1 YAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHL
.::.:..: .::.:. : :. ::....:::.: .::.:::: ::. .. :.:::::.
XP_016 FAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHI
370 380 390 400 410 420
520 530
pF1KE1 LCHGCHMQRLNARQPPANYI
::. :. :.
XP_016 LCKTCNSARIRVLTAKASTDL
430 440
>>XP_011511138 (OMIM: 600700) PREDICTED: lipoma-preferre (449 aa)
initn: 778 init1: 551 opt: 851 Z-score: 443.6 bits: 91.5 E(85289): 5.7e-18
Smith-Waterman score: 881; 33.0% identity (58.7% similar) in 460 aa overlap (90-528:4-438)
60 70 80 90 100 110
pF1KE1 PLEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPT-------RALPLPQSLPPDFRLE
: :: : . : ::. :
XP_011 MVIPNQPPLTATKKSTLKPQPAPQAGPI-----
10 20
120 130 140 150 160
pF1KE1 PTAP--ALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGIS-MGY
:.:: .:.:. . . .: . :: : : .. . .: . . : :.. : . .::
XP_011 PVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGY
30 40 50 60 70 80
170 180 190 200 210 220
pF1KE1 DQRHGSPLP-AGPCLFGPPLAGAPAGYS----PGGVPS-AY---PELHAALDRLYAQRPA
. . :.: .: : :: . . :. :: : .: :. . :: :
XP_011 NTQ---PVPVSGQC--PPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGP-
90 100 110 120 130 140
230 240 250 260 270
pF1KE1 GFGCQESRHSYPPALGSPG--ALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQD
:.: .:.. :. :. : : . : :: . ::: . :
XP_011 GYG---GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYI----TD
150 160 170 180 190
280 290 300 310 320 330
pF1KE1 ELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTC
..: . : ..: : ::.. :: : . . :..: : ..::: :
XP_011 PVSAPCAPPLQPKGGHSGQLG-PSSVAPSFRPEDELEHLTKKMLYDMENPPA-DEYFGRC
200 210 220 230 240 250
340 350 360 370 380 390
pF1KE1 IKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQE
.:.... :....: :.:...:..::.: :. :: . ::.:. ..::: :. .
XP_011 ARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYI-----N
260 270 280 290 300
400 410 420 430 440 450
pF1KE1 AAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKN
. :.: ::.. :.:.::.: ::.::: :: :..:.. ::::::::: .. ..:. :.::.
XP_011 TLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKK
310 320 330 340 350 360
460 470 480 490 500 510
pF1KE1 YAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHL
.::.:..: .::.:. : :. ::....:::.: .::.:::: ::. .. :.:::::.
XP_011 FAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHI
370 380 390 400 410 420
520 530
pF1KE1 LCHGCHMQRLNARQPPANYI
::. :. :.
XP_011 LCKTCNSARIRVLTAKASTDL
430 440
>>XP_016861867 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa)
initn: 804 init1: 551 opt: 851 Z-score: 441.9 bits: 91.7 E(85289): 7.1e-18
Smith-Waterman score: 884; 31.0% identity (56.6% similar) in 542 aa overlap (4-528:94-601)
10 20 30
pF1KE1 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGP
: :.: .. . : . : ::. :.
XP_016 EGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDS
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE1 GKGRLSGL--GGPRKS-GPRGATGGPGDEPLEPAREQGSLDAERNQRGSFEAPRYEGSFP
. :. : ..: : :...::. .. :. : . ..: . :
XP_016 LTSILADLECSSPYKPRPPQSSTGSTASPPV-------STPVTGHKR--MVIPNQPPLTA
130 140 150 160 170
100 110 120 130 140
pF1KE1 AGPPPTRALPLPQSLPPDFRLEPTAP--ALSPRSSFASSSASDASKPSSPRGSLLLDGAG
. . : ::. : :.:: .:.:. . . .: . :: : : .. . .:
XP_016 TKKSTLKPQPAPQAGPI-----PVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQ
180 190 200 210 220
150 160 170 180 190 200
pF1KE1 AGGAGGSRPCSNRTSGIS-MGYDQRHGSPLP-AGPCLFGPPLAGAPAGYS----PGGVPS
. . : :.. : . .::. . :.: .: : :: . . :. :: :
XP_016 PSPHYMAAPSSGQIYGSGPQGYNTQ---PVPVSGQC--PPPSTRGGMDYAYIPPPGLQPE
230 240 250 260 270 280
210 220 230 240 250
pF1KE1 -AY---PELHAALDRLYAQRPAGFGCQESRHSYPPALGSPG--ALAGAGVGAAGPLERRG
.: :. . :: : :.: .:.. :. :. : : . :
XP_016 PGYGYAPNQGRYYEGYYAAGP-GYG---GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQ
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE1 AQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPF
:: . ::: . : ..: . : ..: : ::.. :: :
XP_016 NPPGMYPVTGPKKTYI----TDPVSAPCAPPLQPKGGHSGQLG-PSSVAPSFRPEDELEH
350 360 370 380 390
320 330 340 350 360 370
pF1KE1 VPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCK
. . :..: : : ::: : .:.... :....: :.:...:..::.: :. :: .
XP_016 LTKKMLYDMENPPADE-YFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQ
400 410 420 430 440 450
380 390 400 410 420 430
pF1KE1 AFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCL
::.:. ..::: :. .. :.: ::.. :.:.::.: ::.::: :: :..:.. :
XP_016 PFYAVEKKAYCEPCYI-----NTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSL
460 470 480 490 500
440 450 460 470 480 490
pF1KE1 DGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHC
:::::::: .. ..:. :.::..::.:..: .::.:. : :. ::....:::.: .::.:
XP_016 DGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRC
510 520 530 540 550 560
500 510 520 530
pF1KE1 EDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
::: ::. .. :.:::::.::. :. :.
XP_016 EDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL
570 580 590 600 610
538 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:13:03 2016 done: Sun Nov 6 23:13:04 2016
Total Scan time: 9.740 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]