Result of FASTA (omim) for
pFN21AB3630
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3630, 193 aa
1>>>pF1KB3630 193 - 193 aa - 193 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5357+/-0.000369; mu= 12.0676+/- 0.023
mean_var=80.6668+/-15.761, 0's: 0 Z-trim(115.8): 394 B-trim: 1207 in 2/52
Lambda= 0.142800
statistics sampled from 26086 (26576) to 26086 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.312), width: 16
Scan time: 5.910
The best scores are: opt bits E(85289)
NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 1305 278.1 6.3e-75
NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 1305 278.1 6.3e-75
NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 1305 278.1 6.3e-75
NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 1222 261.0 8.8e-70
NP_001300870 (OMIM: 165390) transforming protein R ( 193) 1222 261.0 8.8e-70
NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 1114 238.7 4.4e-63
NP_001300872 (OMIM: 165390) transforming protein R ( 187) 936 202.0 4.7e-52
NP_001300873 (OMIM: 165390) transforming protein R ( 173) 806 175.2 5.1e-44
NP_008839 (OMIM: 602048) ras-related C3 botulinum ( 192) 726 158.8 5e-39
XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191) 713 156.1 3.2e-38
XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191) 713 156.1 3.2e-38
NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191) 713 156.1 3.2e-38
NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192) 702 153.8 1.6e-37
NP_005043 (OMIM: 602050) ras-related C3 botulinum ( 192) 695 152.4 4.2e-37
NP_001034891 (OMIM: 116952,616737) cell division c ( 191) 690 151.4 8.6e-37
NP_001782 (OMIM: 116952,616737) cell division cont ( 191) 690 151.4 8.6e-37
NP_001300874 (OMIM: 165390) transforming protein R ( 112) 683 149.8 1.5e-36
NP_426359 (OMIM: 116952,616737) cell division cont ( 191) 684 150.1 2e-36
NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210) 671 147.5 1.4e-35
NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205) 670 147.3 1.6e-35
NP_005159 (OMIM: 602924) rho-related GTP-binding p ( 244) 658 144.8 1e-34
NP_001241667 (OMIM: 602924) rho-related GTP-bindin ( 244) 658 144.8 1e-34
NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227) 656 144.4 1.3e-34
XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234) 656 144.4 1.3e-34
NP_065714 (OMIM: 607653) rho-related GTP-binding p ( 214) 636 140.3 2.1e-33
NP_001303236 (OMIM: 602050) ras-related C3 botulin ( 170) 609 134.6 8.3e-32
NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258) 605 133.9 2e-31
XP_006724349 (OMIM: 602049,608203) PREDICTED: ras- ( 161) 602 133.2 2.1e-31
XP_011531028 (OMIM: 605857) PREDICTED: rho-related ( 192) 592 131.2 1e-30
XP_016859205 (OMIM: 605857) PREDICTED: rho-related ( 172) 590 130.7 1.3e-30
XP_006720277 (OMIM: 607653) PREDICTED: rho-related ( 176) 550 122.5 3.9e-28
NP_055285 (OMIM: 609038) rho-related GTP-binding p ( 232) 546 121.8 8.5e-28
XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206) 541 120.7 1.6e-27
XP_016863678 (OMIM: 602037) PREDICTED: rho-related ( 191) 522 116.7 2.3e-26
NP_001265296 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265293 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265292 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265288 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265297 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
XP_016863677 (OMIM: 602037) PREDICTED: rho-related ( 191) 522 116.7 2.3e-26
NP_001265289 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265298 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265294 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_004301 (OMIM: 602037) rho-related GTP-binding p ( 191) 522 116.7 2.3e-26
NP_001265290 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265291 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
NP_001265295 (OMIM: 602037) rho-related GTP-bindin ( 191) 522 116.7 2.3e-26
XP_011511994 (OMIM: 602037) PREDICTED: rho-related ( 191) 522 116.7 2.3e-26
XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157) 437 99.2 3.6e-21
NP_061485 (OMIM: 602048) ras-related C3 botulinum ( 211) 378 87.1 2.1e-17
>>NP_001036143 (OMIM: 165380) rho-related GTP-binding pr (193 aa)
initn: 1305 init1: 1305 opt: 1305 Z-score: 1466.2 bits: 278.1 E(85289): 6.3e-75
Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB3 VRKNKRRRGCPIL
:::::::::::::
NP_001 VRKNKRRRGCPIL
190
>>NP_786886 (OMIM: 165380) rho-related GTP-binding prote (193 aa)
initn: 1305 init1: 1305 opt: 1305 Z-score: 1466.2 bits: 278.1 E(85289): 6.3e-75
Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB3 VRKNKRRRGCPIL
:::::::::::::
NP_786 VRKNKRRRGCPIL
190
>>NP_001036144 (OMIM: 165380) rho-related GTP-binding pr (193 aa)
initn: 1305 init1: 1305 opt: 1305 Z-score: 1466.2 bits: 278.1 E(85289): 6.3e-75
Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB3 VRKNKRRRGCPIL
:::::::::::::
NP_001 VRKNKRRRGCPIL
190
>>NP_001655 (OMIM: 165390) transforming protein RhoA iso (193 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1373.8 bits: 261.0 E(85289): 8.8e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
190
pF1KB3 VRKNKRRRGCPIL
.:..:.. :: .:
NP_001 ARRGKKKSGCLVL
190
>>NP_001300870 (OMIM: 165390) transforming protein RhoA (193 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1373.8 bits: 261.0 E(85289): 8.8e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
190
pF1KB3 VRKNKRRRGCPIL
.:..:.. :: .:
NP_001 ARRGKKKSGCLVL
190
>>NP_004031 (OMIM: 165370) rho-related GTP-binding prote (196 aa)
initn: 1127 init1: 1107 opt: 1114 Z-score: 1253.5 bits: 238.7 E(85289): 4.4e-63
Smith-Waterman score: 1114; 85.8% identity (95.3% similar) in 190 aa overlap (1-190:1-189)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::.:::::::::::::::::
NP_004 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_004 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::.:::.: :::.:::::::...:: :: ::.:. ::::::::::::::::: ::::.::
NP_004 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
130 140 150 160 170 180
190
pF1KB3 VRKNKRRRGCPIL
: ... ::
NP_004 KRYGSQN-GCINCCKVL
190
>>NP_001300872 (OMIM: 165390) transforming protein RhoA (187 aa)
initn: 936 init1: 936 opt: 936 Z-score: 1055.6 bits: 202.0 E(85289): 4.7e-52
Smith-Waterman score: 936; 98.6% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::.:::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPHCVARLECCGTILAQLQPPPPRFKRFPCLSLLSSWGYRRPLP
130 140 150 160 170 180
>>NP_001300873 (OMIM: 165390) transforming protein RhoA (173 aa)
initn: 1084 init1: 806 opt: 806 Z-score: 911.3 bits: 175.2 E(85289): 5.1e-44
Smith-Waterman score: 1040; 81.3% identity (88.1% similar) in 193 aa overlap (1-193:1-173)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYV-----------------
10 20 30 40
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
110 120 130 140 150 160
190
pF1KB3 VRKNKRRRGCPIL
.:..:.. :: .:
NP_001 ARRGKKKSGCLVL
170
>>NP_008839 (OMIM: 602048) ras-related C3 botulinum toxi (192 aa)
initn: 740 init1: 696 opt: 726 Z-score: 821.6 bits: 158.8 E(85289): 5e-39
Smith-Waterman score: 726; 57.7% identity (76.8% similar) in 194 aa overlap (1-193:1-192)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
: :: : :.::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.::::
NP_008 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
:::::::::::::::.:::.:.:::. :: :.::. :: :::.: :::.::::::.: :
NP_008 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
::.:. : ..: . : :. .: ::..:.: :::::: :..:.. ::. : :: :
NP_008 LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC
120 130 140 150 160 170
190
pF1KB3 VRK-NKRRRGCPIL
.::.: : .:
NP_008 PPPVKKRKRKCLLL
180 190
>>XP_005252973 (OMIM: 179505) PREDICTED: rho-related GTP (191 aa)
initn: 719 init1: 700 opt: 713 Z-score: 807.1 bits: 156.1 E(85289): 3.2e-38
Smith-Waterman score: 713; 56.1% identity (77.0% similar) in 187 aa overlap (7-193:5-191)
10 20 30 40 50 60
pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
: :.::::: ::::::: .. . ::. :.::::.:: :. :::. :.: ::::
XP_005 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::.::::: ::::.:.:...:::: :: : ::. .:: ::: : ::.:::.:::.:::
XP_005 AGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
:: . : :.: .. : :. ..:. .:..: : :::::: ..::.::: :.:: :.
XP_005 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN
120 130 140 150 160 170
190
pF1KB3 VRKNKRRRGCPIL
:: :.: .:
XP_005 PTPIKRGRSCILL
180 190
193 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:15:25 2016 done: Sat Nov 5 05:15:26 2016
Total Scan time: 5.910 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]