Result of FASTA (omim) for
pFN21AE6418
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6418, 623 aa
1>>>pF1KE6418 623 - 623 aa - 623 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6411+/-0.000429; mu= 19.0344+/- 0.027
mean_var=103.0764+/-20.448, 0's: 0 Z-trim(113.5): 153 B-trim: 387 in 1/54
Lambda= 0.126327
statistics sampled from 22648 (22822) to 22648 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.268), width: 16
Scan time: 7.610
The best scores are: opt bits E(85289)
NP_009120 (OMIM: 612510) ATP-binding cassette sub- ( 623) 4156 768.7 0
XP_016867128 (OMIM: 612510) PREDICTED: ATP-binding ( 623) 4156 768.7 0
XP_016867129 (OMIM: 612510) PREDICTED: ATP-binding ( 623) 4156 768.7 0
NP_005683 (OMIM: 612510) ATP-binding cassette sub- ( 634) 4156 768.7 0
NP_001081 (OMIM: 603429) ATP-binding cassette sub- ( 807) 1419 269.9 2.4e-71
NP_001020262 (OMIM: 603429) ATP-binding cassette s ( 845) 1404 267.2 1.6e-70
NP_001288759 (OMIM: 605250) multidrug resistance-a ( 784) 201 47.9 0.00015
XP_016875811 (OMIM: 605250) PREDICTED: multidrug r ( 816) 201 48.0 0.00016
XP_016875809 (OMIM: 605250) PREDICTED: multidrug r ( 830) 201 48.0 0.00016
NP_001098985 (OMIM: 605250) multidrug resistance-a ( 859) 201 48.0 0.00016
XP_005256997 (OMIM: 612505) PREDICTED: ATP-binding (1560) 198 47.7 0.00037
NP_009099 (OMIM: 612505) ATP-binding cassette sub- (1581) 198 47.7 0.00037
NP_001275915 (OMIM: 612505) ATP-binding cassette s (1616) 198 47.7 0.00038
XP_005256995 (OMIM: 612505) PREDICTED: ATP-binding (1621) 198 47.7 0.00038
NP_001275914 (OMIM: 612505) ATP-binding cassette s (1621) 198 47.7 0.00038
XP_016878732 (OMIM: 158343) PREDICTED: multidrug r ( 931) 183 44.7 0.0017
XP_016879500 (OMIM: 612507) PREDICTED: ATP-binding (1632) 185 45.3 0.002
XP_016879897 (OMIM: 612504) PREDICTED: ATP-binding ( 932) 181 44.4 0.0022
XP_016871164 (OMIM: 237500,601107) PREDICTED: cana ( 892) 180 44.2 0.0024
XP_006717694 (OMIM: 237500,601107) PREDICTED: cana ( 895) 180 44.2 0.0024
XP_011542438 (OMIM: 605454) PREDICTED: ATP-binding ( 442) 176 43.2 0.0024
XP_011537593 (OMIM: 237500,601107) PREDICTED: cana ( 916) 180 44.2 0.0024
XP_011522876 (OMIM: 612504) PREDICTED: ATP-binding (1300) 181 44.5 0.0028
XP_011542437 (OMIM: 605454) PREDICTED: ATP-binding ( 559) 176 43.2 0.0028
XP_016879895 (OMIM: 612504) PREDICTED: ATP-binding (1422) 181 44.5 0.0029
XP_016879896 (OMIM: 612504) PREDICTED: ATP-binding (1422) 181 44.5 0.0029
XP_006717693 (OMIM: 237500,601107) PREDICTED: cana (1313) 180 44.3 0.0032
NP_525023 (OMIM: 612504) ATP-binding cassette sub- (1617) 181 44.6 0.0032
XP_016879894 (OMIM: 612504) PREDICTED: ATP-binding (1617) 181 44.6 0.0032
XP_016879893 (OMIM: 612504) PREDICTED: ATP-binding (1617) 181 44.6 0.0032
NP_036221 (OMIM: 605454) ATP-binding cassette sub- ( 738) 176 43.4 0.0035
NP_000383 (OMIM: 237500,601107) canalicular multis (1545) 180 44.4 0.0035
XP_011520784 (OMIM: 177850,264800,603234,614473) P ( 887) 173 42.9 0.0058
XP_016878703 (OMIM: 177850,264800,603234,614473) P (1166) 173 43.0 0.007
XP_011520783 (OMIM: 177850,264800,603234,614473) P (1389) 173 43.1 0.0079
XP_011520782 (OMIM: 177850,264800,603234,614473) P (1389) 173 43.1 0.0079
XP_016878702 (OMIM: 177850,264800,603234,614473) P (1389) 173 43.1 0.0079
NP_001162 (OMIM: 177850,264800,603234,614473) mult (1503) 173 43.1 0.0084
XP_006719088 (OMIM: 239850,601439,608569,614050) P (1536) 173 43.1 0.0085
XP_005253346 (OMIM: 239850,601439,608569,614050) P (1536) 173 43.1 0.0085
XP_011520781 (OMIM: 177850,264800,603234,614473) P (1492) 172 42.9 0.0095
>>NP_009120 (OMIM: 612510) ATP-binding cassette sub-fami (623 aa)
initn: 4156 init1: 4156 opt: 4156 Z-score: 4099.3 bits: 768.7 E(85289): 0
Smith-Waterman score: 4156; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE6 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
550 560 570 580 590 600
610 620
pF1KE6 YKEHLKSKLVDEEPQLTKRTHNV
:::::::::::::::::::::::
NP_009 YKEHLKSKLVDEEPQLTKRTHNV
610 620
>>XP_016867128 (OMIM: 612510) PREDICTED: ATP-binding cas (623 aa)
initn: 4156 init1: 4156 opt: 4156 Z-score: 4099.3 bits: 768.7 E(85289): 0
Smith-Waterman score: 4156; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE6 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
550 560 570 580 590 600
610 620
pF1KE6 YKEHLKSKLVDEEPQLTKRTHNV
:::::::::::::::::::::::
XP_016 YKEHLKSKLVDEEPQLTKRTHNV
610 620
>>XP_016867129 (OMIM: 612510) PREDICTED: ATP-binding cas (623 aa)
initn: 4156 init1: 4156 opt: 4156 Z-score: 4099.3 bits: 768.7 E(85289): 0
Smith-Waterman score: 4156; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE6 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
550 560 570 580 590 600
610 620
pF1KE6 YKEHLKSKLVDEEPQLTKRTHNV
:::::::::::::::::::::::
XP_016 YKEHLKSKLVDEEPQLTKRTHNV
610 620
>>NP_005683 (OMIM: 612510) ATP-binding cassette sub-fami (634 aa)
initn: 4156 init1: 4156 opt: 4156 Z-score: 4099.2 bits: 768.7 E(85289): 0
Smith-Waterman score: 4156; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE6 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILA
550 560 570 580 590 600
610 620
pF1KE6 YKEHLKSKLVDEEPQLTKRTHNV
:::::::::::::::::::::::
NP_005 YKEHLKSKLVDEEPQLTKRTHNVCTLTLASLPRP
610 620 630
>>NP_001081 (OMIM: 603429) ATP-binding cassette sub-fami (807 aa)
initn: 1383 init1: 525 opt: 1419 Z-score: 1402.0 bits: 269.9 E(85289): 2.4e-71
Smith-Waterman score: 1419; 38.8% identity (70.5% similar) in 614 aa overlap (5-605:196-793)
10 20 30
pF1KE6 MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVV
: ... :..: : .. :..:.:.
NP_001 SEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKA----
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE6 TEPQVAEKNEANGRETTEVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLT
. ::. : . :... . . .:: ...: . ..: :..:... ..:..
NP_001 ---KKAEQMEYE-RQVASLKAANAAENDFSVSQAEMSSRQAMLE---NASDIKLEKFSIS
230 240 250 260 270
100 110 120 130 140 150
pF1KE6 FHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPS
::.::. .. : . .::::::.: :: ::. ::. :..: . :: .::. .:. .
NP_001 AHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVV-A
280 290 300 310 320 330
160 170 180 190 200
pF1KE6 DKTP-LHCVMEVDTERAMLEKEAERLAHE-----DAECEKLMELYERLEELDADKAEMRA
:.:: .. :...::.: : .: .:: . :. :.: ..::.:. : :: .:
NP_001 DETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAEAKA
340 350 360 370 380 390
210 220 230 240 250 260
pF1KE6 SRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLE
::: :::: : :: . . :::::::::.::::::..: .:.::::::::::.: .::.
NP_001 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN
400 410 420 430 440 450
270 280 290 300 310 320
pF1KE6 EELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRF
. :. ... :..:::.: ::. :::.:::. ..:.:: ::: . : . ... .:..
NP_001 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQY
460 470 480 490 500 510
330 340 350 360 370 380
pF1KE6 HWEQDQIAHMK--NYIARFGHGSAK--LARQAQS---KEKTLQKMMASGLTERVVSDKTL
. .. .. ..: . .. .. ..: :.:. :. :.. ... : : .: .. :.
NP_001 EKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPELLKRP-KEYTV
520 530 540 550 560 570
390 400 410 420 430 440
pF1KE6 SFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLK
: :: . :::. ...:.: : . : ...::.::::.:.:. .:::::.::::::
NP_001 RFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRICIVGPNGVGKSTLLL
580 590 600 610 620 630
450 460 470 480 490 500
pF1KE6 LLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIG
::::.: :: : .::. ..::: ..:. ::: .. .: ::... . .. :: .:
NP_001 LLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNL--PYQDARKCLG
640 650 660 670 680
510 520 530 540 550 560
pF1KE6 RYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINE
:.:: .. .. : .:: ::: :: .: :: ..: .:.::::::.::::.::::..::::
NP_001 RFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINE
690 700 710 720 730 740
570 580 590 600 610 620
pF1KE6 FEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTH
..:....:::: ::: .. ..:: :.:.... ::. ::...
NP_001 YKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMVSRPRE
750 760 770 780 790 800
pF1KE6 NV
>>NP_001020262 (OMIM: 603429) ATP-binding cassette sub-f (845 aa)
initn: 1383 init1: 525 opt: 1404 Z-score: 1387.0 bits: 267.2 E(85289): 1.6e-70
Smith-Waterman score: 1413; 38.1% identity (70.5% similar) in 627 aa overlap (2-605:213-831)
10 20 30
pF1KE6 MPSDLAKKKAAKKKEAAKARQRPRKGHEENG
: .:.:: : ..... . . .. .::.:
NP_001 SKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGG
190 200 210 220 230 240
40 50 60 70 80
pF1KE6 DV-VTEP--QVAEKNEANGRETTEVDLLTKELE-------DFEMKKAAARAVTGVLASHP
. . .: ....:.. . .. : . . :. :: ...: . ..:
NP_001 ESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAML---E
250 260 270 280 290
90 100 110 120 130 140
pF1KE6 NSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEH
:..:... ..:.. ::.::. .. : . .::::::.: :: ::. ::. :..: . :: .
NP_001 NASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPN
300 310 320 330 340 350
150 160 170 180 190
pF1KE6 IDIYHLTREMPPSDKTP-LHCVMEVDTERAMLEKEAERLAHE-----DAECEKLMELYER
::. .:. .:.:: .. :...::.: : .: .:: . :. :.: ..::.
NP_001 IDVLLCEQEVV-ADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEE
360 370 380 390 400 410
200 210 220 230 240 250
pF1KE6 LEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEP
:. : :: .: ::: :::: : :: . . :::::::::.::::::..: .:.::::
NP_001 LRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEP
420 430 440 450 460 470
260 270 280 290 300 310
pF1KE6 TNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVK
::::::.: .::.. :. ... :..:::.: ::. :::.:::. ..:.:: ::: . :
NP_001 TNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKK
480 490 500 510 520 530
320 330 340 350 360
pF1KE6 TRLELEENQMKRFHWEQDQIAHMK--NYIARFGHGSAK--LARQAQS---KEKTLQKMMA
. ... .:... .. .. ..: . .. .. ..: :.:. :. :.. ... :
NP_001 MYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEA
540 550 560 570 580 590
370 380 390 400 410 420
pF1KE6 SGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVAL
: .: .. :. : :: . :::. ...:.: : . : ...::.::::.:.:. .
NP_001 PELLKRP-KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRICI
600 610 620 630 640 650
430 440 450 460 470 480
pF1KE6 VGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYP
:::::.:::::: ::::.: :: : .::. ..::: ..:. ::: .. .: ::... .
NP_001 VGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFN
660 670 680 690 700 710
490 500 510 520 530 540
pF1KE6 EIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLD
.. :: .::.:: .. .. : .:: ::: :: .: :: ..: .:.::::::.::
NP_001 L--PYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLD
720 730 740 750 760 770
550 560 570 580 590 600
pF1KE6 IETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSK
::.::::..::::..:....:::: ::: .. ..:: :.:.... ::. ::...
NP_001 IESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEA
780 790 800 810 820 830
610 620
pF1KE6 LVDEEPQLTKRTHNV
NP_001 LGEVMVSRPRE
840
>>NP_001288759 (OMIM: 605250) multidrug resistance-assoc (784 aa)
initn: 200 init1: 122 opt: 201 Z-score: 202.5 bits: 47.9 E(85289): 0.00015
Smith-Waterman score: 201; 27.2% identity (55.2% similar) in 232 aa overlap (385-607:327-548)
360 370 380 390 400 410
pF1KE6 QAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTK--DGPCI
.: :: .. ::. . . : . : .
NP_001 AIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGK---KMVHVQDFTAFWDKASETPTL
300 310 320 330 340 350
420 430 440 450 460 470
pF1KE6 YNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVK-IGRYHQHLQE
..: : . .:.::: :::::.::. . ::: :. :.. :... ... ..
NP_001 -QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSG
360 370 380 390 400 410
480 490 500 510 520
pF1KE6 QLDLD-LSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRN--LSDGQKCRVCLA
: . : .: . : .. . ..: . . : : :. :: ::: :: ::
NP_001 TLRSNILFGKKYEKERYEKVIKACALKKDL-QLLEDGDLTVIGDRGTTLSGGQKARVNLA
420 430 440 450 460 470
530 540 550 560 570 580
pF1KE6 WLAWQNPHMLFLDEPTNHLDIETIDALAD-AINEF--EGGMMLVSHDFRLIQQVAQEIWV
..:. . .::.: . .: :. : . : .. : .::.:... .. ..: . .
NP_001 RAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILIL
480 490 500 510 520 530
590 600 610 620
pF1KE6 CEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV
. . . : : .: : :::
NP_001 KDGKMVQK--G---TYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWS
540 550 560 570 580
>>XP_016875811 (OMIM: 605250) PREDICTED: multidrug resis (816 aa)
initn: 200 init1: 122 opt: 201 Z-score: 202.3 bits: 48.0 E(85289): 0.00016
Smith-Waterman score: 201; 27.2% identity (55.2% similar) in 232 aa overlap (385-607:359-580)
360 370 380 390 400 410
pF1KE6 QAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTK--DGPCI
.: :: .. ::. . . : . : .
XP_016 AIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGK---KMVHVQDFTAFWDKASETPTL
330 340 350 360 370 380
420 430 440 450 460 470
pF1KE6 YNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVK-IGRYHQHLQE
..: : . .:.::: :::::.::. . ::: :. :.. :... ... ..
XP_016 -QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSG
390 400 410 420 430 440
480 490 500 510 520
pF1KE6 QLDLD-LSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRN--LSDGQKCRVCLA
: . : .: . : .. . ..: . . : : :. :: ::: :: ::
XP_016 TLRSNILFGKKYEKERYEKVIKACALKKDL-QLLEDGDLTVIGDRGTTLSGGQKARVNLA
450 460 470 480 490 500
530 540 550 560 570 580
pF1KE6 WLAWQNPHMLFLDEPTNHLDIETIDALAD-AINEF--EGGMMLVSHDFRLIQQVAQEIWV
..:. . .::.: . .: :. : . : .. : .::.:... .. ..: . .
XP_016 RAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILIL
510 520 530 540 550 560
590 600 610 620
pF1KE6 CEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV
. . . : : .: : :::
XP_016 KDGKMVQK--G---TYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWS
570 580 590 600 610
>>XP_016875809 (OMIM: 605250) PREDICTED: multidrug resis (830 aa)
initn: 200 init1: 122 opt: 201 Z-score: 202.2 bits: 48.0 E(85289): 0.00016
Smith-Waterman score: 201; 27.2% identity (55.2% similar) in 232 aa overlap (385-607:402-623)
360 370 380 390 400 410
pF1KE6 QAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTK--DGPCI
.: :: .. ::. . . : . : .
XP_016 AIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGK---KMVHVQDFTAFWDKASETPTL
380 390 400 410 420
420 430 440 450 460 470
pF1KE6 YNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVK-IGRYHQHLQE
..: : . .:.::: :::::.::. . ::: :. :.. :... ... ..
XP_016 -QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSG
430 440 450 460 470 480
480 490 500 510 520
pF1KE6 QLDLD-LSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRN--LSDGQKCRVCLA
: . : .: . : .. . ..: . . : : :. :: ::: :: ::
XP_016 TLRSNILFGKKYEKERYEKVIKACALKKDL-QLLEDGDLTVIGDRGTTLSGGQKARVNLA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE6 WLAWQNPHMLFLDEPTNHLDIETIDALAD-AINEF--EGGMMLVSHDFRLIQQVAQEIWV
..:. . .::.: . .: :. : . : .. : .::.:... .. ..: . .
XP_016 RAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILIL
550 560 570 580 590 600
590 600 610 620
pF1KE6 CEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV
. . . : : .: : :::
XP_016 KDGKMVQK--G---TYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWS
610 620 630 640 650 660
>>NP_001098985 (OMIM: 605250) multidrug resistance-assoc (859 aa)
initn: 200 init1: 122 opt: 201 Z-score: 202.0 bits: 48.0 E(85289): 0.00016
Smith-Waterman score: 201; 27.2% identity (55.2% similar) in 232 aa overlap (385-607:402-623)
360 370 380 390 400 410
pF1KE6 QAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTK--DGPCI
.: :: .. ::. . . : . : .
NP_001 AIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGK---KMVHVQDFTAFWDKASETPTL
380 390 400 410 420
420 430 440 450 460 470
pF1KE6 YNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVK-IGRYHQHLQE
..: : . .:.::: :::::.::. . ::: :. :.. :... ... ..
NP_001 -QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSG
430 440 450 460 470 480
480 490 500 510 520
pF1KE6 QLDLD-LSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRN--LSDGQKCRVCLA
: . : .: . : .. . ..: . . : : :. :: ::: :: ::
NP_001 TLRSNILFGKKYEKERYEKVIKACALKKDL-QLLEDGDLTVIGDRGTTLSGGQKARVNLA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE6 WLAWQNPHMLFLDEPTNHLDIETIDALAD-AINEF--EGGMMLVSHDFRLIQQVAQEIWV
..:. . .::.: . .: :. : . : .. : .::.:... .. ..: . .
NP_001 RAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILIL
550 560 570 580 590 600
590 600 610 620
pF1KE6 CEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV
. . . : : .: : :::
NP_001 KDGKMVQK--G---TYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWS
610 620 630 640 650 660
623 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:05:57 2016 done: Tue Nov 8 13:05:58 2016
Total Scan time: 7.610 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]