Result of FASTA (omim) for
pFN21AE4355
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4355, 372 aa
1>>>pF1KE4355 372 - 372 aa - 372 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1834+/-0.000379; mu= 17.1180+/- 0.024
mean_var=61.0773+/-12.215, 0's: 0 Z-trim(111.2): 31 B-trim: 36 in 2/50
Lambda= 0.164110
statistics sampled from 19666 (19696) to 19666 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.231), width: 16
Scan time: 7.070
The best scores are: opt bits E(85289)
NP_000189 (OMIM: 201810,613890) 3 beta-hydroxyster ( 372) 2463 591.8 8.1e-169
NP_001159592 (OMIM: 201810,613890) 3 beta-hydroxys ( 372) 2463 591.8 8.1e-169
NP_001315544 (OMIM: 109715) 3 beta-hydroxysteroid ( 373) 2337 562.0 7.7e-160
NP_000853 (OMIM: 109715) 3 beta-hydroxysteroid deh ( 373) 2337 562.0 7.7e-160
XP_016856608 (OMIM: 109715) PREDICTED: 3 beta-hydr ( 375) 2337 562.0 7.8e-160
XP_005255658 (OMIM: 607764,607765) PREDICTED: 3 be ( 369) 820 202.9 1e-51
XP_011544263 (OMIM: 607764,607765) PREDICTED: 3 be ( 369) 820 202.9 1e-51
XP_011544262 (OMIM: 607764,607765) PREDICTED: 3 be ( 369) 820 202.9 1e-51
NP_079469 (OMIM: 607764,607765) 3 beta-hydroxyster ( 369) 820 202.9 1e-51
XP_011521774 (OMIM: 616164) PREDICTED: short-chain ( 390) 462 118.1 3.5e-26
XP_011521773 (OMIM: 616164) PREDICTED: short-chain ( 390) 462 118.1 3.5e-26
XP_005256314 (OMIM: 616164) PREDICTED: short-chain ( 393) 462 118.1 3.5e-26
NP_660151 (OMIM: 616164) short-chain dehydrogenase ( 393) 462 118.1 3.5e-26
NP_001136249 (OMIM: 607764,607765) 3 beta-hydroxys ( 196) 396 102.3 9.8e-22
XP_011544264 (OMIM: 607764,607765) PREDICTED: 3 be ( 196) 396 102.3 9.8e-22
NP_001136250 (OMIM: 607764,607765) 3 beta-hydroxys ( 196) 396 102.3 9.8e-22
XP_016879221 (OMIM: 607764,607765) PREDICTED: 3 be ( 196) 396 102.3 9.8e-22
XP_011529480 (OMIM: 300275,300831,308050) PREDICTE ( 373) 303 80.4 7.2e-15
NP_057006 (OMIM: 300275,300831,308050) sterol-4-al ( 373) 303 80.4 7.2e-15
NP_001123237 (OMIM: 300275,300831,308050) sterol-4 ( 373) 303 80.4 7.2e-15
XP_016885053 (OMIM: 300275,300831,308050) PREDICTE ( 389) 303 80.5 7.4e-15
NP_055120 (OMIM: 616145,616146) dTDP-D-glucose 4,6 ( 350) 189 53.4 9.1e-07
NP_001291359 (OMIM: 616145,616146) dTDP-D-glucose ( 318) 151 44.4 0.00043
XP_011519367 (OMIM: 616145,616146) PREDICTED: dTDP ( 318) 151 44.4 0.00043
XP_011519368 (OMIM: 616145,616146) PREDICTED: dTDP ( 318) 151 44.4 0.00043
NP_001008217 (OMIM: 230350,606953) UDP-glucose 4-e ( 348) 149 44.0 0.00064
NP_001121093 (OMIM: 230350,606953) UDP-glucose 4-e ( 348) 149 44.0 0.00064
NP_000394 (OMIM: 230350,606953) UDP-glucose 4-epim ( 348) 149 44.0 0.00064
>>NP_000189 (OMIM: 201810,613890) 3 beta-hydroxysteroid (372 aa)
initn: 2463 init1: 2463 opt: 2463 Z-score: 3151.8 bits: 591.8 E(85289): 8.1e-169
Smith-Waterman score: 2463; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
310 320 330 340 350 360
370
pF1KE4 DRHKETLKSKTQ
::::::::::::
NP_000 DRHKETLKSKTQ
370
>>NP_001159592 (OMIM: 201810,613890) 3 beta-hydroxystero (372 aa)
initn: 2463 init1: 2463 opt: 2463 Z-score: 3151.8 bits: 591.8 E(85289): 8.1e-169
Smith-Waterman score: 2463; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
310 320 330 340 350 360
370
pF1KE4 DRHKETLKSKTQ
::::::::::::
NP_001 DRHKETLKSKTQ
370
>>NP_001315544 (OMIM: 109715) 3 beta-hydroxysteroid dehy (373 aa)
initn: 2337 init1: 2337 opt: 2337 Z-score: 2990.6 bits: 562.0 E(85289): 7.7e-160
Smith-Waterman score: 2337; 93.8% identity (98.1% similar) in 371 aa overlap (2-372:3-373)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLE
:::::::::::.:::::.::::.::::::::.::::: ::::::::::::.:::::::
NP_001 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 GDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTL
::::::::::::::::::::::::::::::::.:::.:::::::::::::::::::: ::
NP_001 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 YTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
::::::: ::::::. ::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEV
.:::::::.::::::::::::::::::::: ::::::::::::::.::.::::::::::.
NP_001 QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 VSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
::::: :::.:.:::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
310 320 330 340 350 360
360 370
pF1KE4 VDRHKETLKSKTQ
:::::::::::::
NP_001 VDRHKETLKSKTQ
370
>>NP_000853 (OMIM: 109715) 3 beta-hydroxysteroid dehydro (373 aa)
initn: 2337 init1: 2337 opt: 2337 Z-score: 2990.6 bits: 562.0 E(85289): 7.7e-160
Smith-Waterman score: 2337; 93.8% identity (98.1% similar) in 371 aa overlap (2-372:3-373)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLE
:::::::::::.:::::.::::.::::::::.::::: ::::::::::::.:::::::
NP_000 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 GDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_000 GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTL
::::::::::::::::::::::::::::::::.:::.:::::::::::::::::::: ::
NP_000 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 YTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
::::::: ::::::. ::::::::::::::::::::::::::::::::::::::::::::
NP_000 YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEV
.:::::::.::::::::::::::::::::: ::::::::::::::.::.::::::::::.
NP_000 QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 VSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
::::: :::.:.:::::: :::::::::::::::::::::::::::::::::::::::::
NP_000 VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
310 320 330 340 350 360
360 370
pF1KE4 VDRHKETLKSKTQ
:::::::::::::
NP_000 VDRHKETLKSKTQ
370
>>XP_016856608 (OMIM: 109715) PREDICTED: 3 beta-hydroxys (375 aa)
initn: 2337 init1: 2337 opt: 2337 Z-score: 2990.5 bits: 562.0 E(85289): 7.8e-160
Smith-Waterman score: 2337; 93.8% identity (98.1% similar) in 371 aa overlap (2-372:5-375)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTV
:::::::::::.:::::.::::.::::::::.::::: ::::::::::::.:::::
XP_016 MAMTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVP
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 LEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGD
::::::::::::::::::::::::::::::::::.:::.::::::::::::::::::::
XP_016 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 TLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALR
::::::::: ::::::. ::::::::::::::::::::::::::::::::::::::::::
XP_016 TLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 ALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLL
::.:::::::.::::::::::::::::::::: ::::::::::::::.::.:::::::::
XP_016 ALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 EVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVG
:.::::: :::.:.:::::: :::::::::::::::::::::::::::::::::::::::
XP_016 EIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVG
310 320 330 340 350 360
360 370
pF1KE4 SLVDRHKETLKSKTQ
:::::::::::::::
XP_016 SLVDRHKETLKSKTQ
370
>>XP_005255658 (OMIM: 607764,607765) PREDICTED: 3 beta-h (369 aa)
initn: 583 init1: 525 opt: 820 Z-score: 1049.6 bits: 202.9 E(85289): 1e-51
Smith-Waterman score: 820; 40.4% identity (69.5% similar) in 354 aa overlap (6-356:13-361)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
XP_005 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
XP_005 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
XP_005 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNP-VYVGNVAWA
...: : ::::::: ::::: .. ..: .: : . :. . ::::::::
XP_005 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 HILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLM
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: :: :.
XP_005 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
... : ....:: :. : : .: .:....:..:: : :::: ..:.::.:::...
XP_005 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
300 310 320 330 340 350
360 370
pF1KE4 KTVEWVGSLVDRHKETLKSKTQ
.:. ::
XP_005 RTILWVQAATGSAQ
360
>>XP_011544263 (OMIM: 607764,607765) PREDICTED: 3 beta-h (369 aa)
initn: 583 init1: 525 opt: 820 Z-score: 1049.6 bits: 202.9 E(85289): 1e-51
Smith-Waterman score: 820; 40.4% identity (69.5% similar) in 354 aa overlap (6-356:13-361)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
XP_011 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
XP_011 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
XP_011 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNP-VYVGNVAWA
...: : ::::::: ::::: .. ..: .: : . :. . ::::::::
XP_011 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 HILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLM
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: :: :.
XP_011 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
... : ....:: :. : : .: .:....:..:: : :::: ..:.::.:::...
XP_011 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
300 310 320 330 340 350
360 370
pF1KE4 KTVEWVGSLVDRHKETLKSKTQ
.:. ::
XP_011 RTILWVQAATGSAQ
360
>>XP_011544262 (OMIM: 607764,607765) PREDICTED: 3 beta-h (369 aa)
initn: 583 init1: 525 opt: 820 Z-score: 1049.6 bits: 202.9 E(85289): 1e-51
Smith-Waterman score: 820; 40.4% identity (69.5% similar) in 354 aa overlap (6-356:13-361)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
XP_011 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
XP_011 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
XP_011 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNP-VYVGNVAWA
...: : ::::::: ::::: .. ..: .: : . :. . ::::::::
XP_011 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 HILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLM
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: :: :.
XP_011 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
... : ....:: :. : : .: .:....:..:: : :::: ..:.::.:::...
XP_011 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
300 310 320 330 340 350
360 370
pF1KE4 KTVEWVGSLVDRHKETLKSKTQ
.:. ::
XP_011 RTILWVQAATGSAQ
360
>>NP_079469 (OMIM: 607764,607765) 3 beta-hydroxysteroid (369 aa)
initn: 583 init1: 525 opt: 820 Z-score: 1049.6 bits: 202.9 E(85289): 1e-51
Smith-Waterman score: 820; 40.4% identity (69.5% similar) in 354 aa overlap (6-356:13-361)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
NP_079 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
NP_079 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
NP_079 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNP-VYVGNVAWA
...: : ::::::: ::::: .. ..: .: : . :. . ::::::::
NP_079 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 HILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLM
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: :: :.
NP_079 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
... : ....:: :. : : .: .:....:..:: : :::: ..:.::.:::...
NP_079 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
300 310 320 330 340 350
360 370
pF1KE4 KTVEWVGSLVDRHKETLKSKTQ
.:. ::
NP_079 RTILWVQAATGSAQ
360
>>XP_011521774 (OMIM: 616164) PREDICTED: short-chain deh (390 aa)
initn: 293 init1: 149 opt: 462 Z-score: 591.1 bits: 118.1 E(85289): 3.5e-26
Smith-Waterman score: 462; 34.8% identity (61.6% similar) in 310 aa overlap (58-355:51-346)
30 40 50 60 70 80
pF1KE4 LKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDV
..::: ...: ::..:. :.. .
XP_011 LGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVT----CVFHI
30 40 50 60 70
90 100 110 120 130 140
pF1KE4 --FGVTHRES-----IMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNG
.:.. ::. : .:::.::. .:..: . :: ..:::...: . ..:.::
XP_011 ASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGG---QVIRNG
80 90 100 110 120 130
150 160 170 180 190
pF1KE4 HEEEPLE--NTWPTPYPYSKKLAEKAVLAANGWNLKNGD-TLYTCALRPTYIYGEGGPFL
: : . : : .:..::. :: ::. : :: .: ::::::. ::: :
XP_011 DESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRH
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE4 SASINEALNNNGILSSV--GKFSTVNPVYVGNVAWAHILALRALRDPKKAPSVRGQFYYI
: ... :... : : :. :.: :.. ::::: .::: :. . :: :.:
XP_011 LPRIVSYIEK-GLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR-ADKGHIASGQPYFI
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE4 SDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFN
:: : .... . : . .: . : :::::.: ..:: :.: :.:. .:..:: ..
XP_011 SDGRPVNNFEFFRP-LVEGLGYTFPST-RLPLTLVYCFAFLTEMVHFILGRLYNFQPFLT
260 270 280 290 300
320 330 340 350 360 370
pF1KE4 RHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
: : .. . :: .::...:.:: . :..:::
XP_011 RTEVYKTGVTHYFSLEKAKKELGYK---AQPFDLQEAVEWFKAHGHGRSSGSRDSECFVW
310 320 330 340 350 360
XP_011 DGLLVFLLIIAVLMWLPSSVILSL
370 380 390
372 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:06:30 2016 done: Sun Nov 6 02:06:32 2016
Total Scan time: 7.070 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]