Result of FASTA (ccds) for
pFN21AE4148
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4148, 583 aa
1>>>pF1KE4148 583 - 583 aa - 583 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7316+/-0.00097; mu= 12.1836+/- 0.058
mean_var=94.2715+/-18.990, 0's: 0 Z-trim(106.8): 68 B-trim: 0 in 0/51
Lambda= 0.132094
statistics sampled from 9106 (9174) to 9106 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.282), width: 16
Scan time: 3.680
The best scores are: opt bits E(32554)
CCDS1325.1 RALGPS2 gene_id:55103|Hs108|chr1 ( 583) 3820 738.5 5.3e-213
CCDS65733.1 RALGPS2 gene_id:55103|Hs108|chr1 ( 557) 2699 524.9 1e-148
CCDS35143.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 557) 1758 345.6 1e-94
CCDS55346.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 529) 1556 307.1 3.7e-83
CCDS55345.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 537) 1556 307.1 3.7e-83
CCDS55344.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 305) 1471 290.8 1.7e-78
CCDS42065.1 RASGRF1 gene_id:5923|Hs108|chr15 ( 489) 442 94.7 2.8e-19
CCDS45320.1 RASGRF1 gene_id:5923|Hs108|chr15 (1257) 442 94.9 6.5e-19
CCDS10309.1 RASGRF1 gene_id:5923|Hs108|chr15 (1273) 442 94.9 6.5e-19
CCDS4052.1 RASGRF2 gene_id:5924|Hs108|chr5 (1237) 429 92.4 3.5e-18
CCDS1802.1 SOS1 gene_id:6654|Hs108|chr2 (1333) 401 87.1 1.5e-16
CCDS9697.1 SOS2 gene_id:6655|Hs108|chr14 (1332) 378 82.7 3.2e-15
CCDS48047.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1077) 328 73.1 2e-12
CCDS78450.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1094) 328 73.2 2e-12
CCDS48048.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1095) 328 73.2 2e-12
CCDS74604.1 RAPGEF4 gene_id:11069|Hs108|chr2 ( 791) 310 69.7 1.6e-11
CCDS63061.1 RAPGEF4 gene_id:11069|Hs108|chr2 ( 840) 310 69.7 1.7e-11
CCDS63060.1 RAPGEF4 gene_id:11069|Hs108|chr2 ( 858) 310 69.7 1.7e-11
CCDS42776.1 RAPGEF4 gene_id:11069|Hs108|chr2 ( 867) 310 69.7 1.7e-11
CCDS42775.1 RAPGEF4 gene_id:11069|Hs108|chr2 (1011) 310 69.7 2e-11
CCDS55093.1 RAPGEF5 gene_id:9771|Hs108|chr7 ( 730) 306 68.9 2.5e-11
CCDS11363.1 RAPGEFL1 gene_id:51195|Hs108|chr17 ( 456) 297 67.1 5.5e-11
CCDS77023.1 RAPGEFL1 gene_id:51195|Hs108|chr17 ( 505) 297 67.1 6e-11
CCDS77022.1 RAPGEFL1 gene_id:51195|Hs108|chr17 ( 511) 297 67.1 6e-11
CCDS54346.1 RASGRP3 gene_id:25780|Hs108|chr2 ( 689) 299 67.6 6e-11
CCDS43277.1 RAPGEF2 gene_id:9693|Hs108|chr4 (1499) 302 68.2 8.1e-11
CCDS46256.1 RASGRP3 gene_id:25780|Hs108|chr2 ( 690) 296 67.0 9e-11
>>CCDS1325.1 RALGPS2 gene_id:55103|Hs108|chr1 (583 aa)
initn: 3820 init1: 3820 opt: 3820 Z-score: 3937.5 bits: 738.5 E(32554): 5.3e-213
Smith-Waterman score: 3820; 100.0% identity (100.0% similar) in 583 aa overlap (1-583:1-583)
10 20 30 40 50 60
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 HSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 WTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 WTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTD
490 500 510 520 530 540
550 560 570 580
pF1KE4 SEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
:::::::::::::::::::::::::::::::::::::::::::
CCDS13 SEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
550 560 570 580
>>CCDS65733.1 RALGPS2 gene_id:55103|Hs108|chr1 (557 aa)
initn: 3632 init1: 2699 opt: 2699 Z-score: 2783.3 bits: 524.9 E(32554): 1e-148
Smith-Waterman score: 3584; 95.5% identity (95.5% similar) in 583 aa overlap (1-583:1-557)
10 20 30 40 50 60
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 DVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 LSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 DNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 DLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 VGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 TFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFE-----
370 380 390 400 410
430 440 450 460 470 480
pF1KE4 HSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVAS
:::::::::::::::::::::::::::::::::::::::
CCDS65 ---------------------SSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVAS
420 430 440 450
490 500 510 520 530 540
pF1KE4 WTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 WTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTD
460 470 480 490 500 510
550 560 570 580
pF1KE4 SEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
:::::::::::::::::::::::::::::::::::::::::::
CCDS65 SEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
520 530 540 550
>>CCDS35143.1 RALGPS1 gene_id:9649|Hs108|chr9 (557 aa)
initn: 2252 init1: 1189 opt: 1758 Z-score: 1814.1 bits: 345.6 E(32554): 1e-94
Smith-Waterman score: 2287; 62.0% identity (81.6% similar) in 587 aa overlap (5-583:5-557)
10 20 30 40 50
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLSDKGSEL-KKSFDAVVFDVLKVTPEEYAGQITL
:: .:: ..... . ::::.:: .. . .::.::::::::::::::.:.::::
CCDS35 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 MDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAE
::.::::::::.::.::::.::::.: :::.::::::::.:::::::::: :::::::::
CCDS35 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 VLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSK
.:::..: :::: ::::::.::.:::.::::::::::::::::.::::::::::.:.:::
CCDS35 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 EDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRII
:::::: :.:: ::::.: :::::::: :: :::::::..:::.::::::: ::::::::
CCDS35 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 SDLQQSCEYD-IPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASRE
.::: :: :: . ::::::::.::.::::::::::::::::::.::::.:.:: ..:.:
CCDS35 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 DLVGPEVGA-SPQSGRKSVAAEGAL---LPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNT
::.:: .:. : . .:. . . .. :: ::: :: ::: :::: :.. ....
CCDS35 DLAGPSAGSGSARFSRRPTCPDTSVAGSLP-TPPVPR------HRKSHSLGNNMMCQLSV
310 320 330 340 350
360 370 380 390 400 410
pF1KE4 AEFKSATFPNAGPRHLLDDSVMEPHAPSRGQA--ESSTLSSGISIGSSDGSELSEETSWP
.: ::::::. ::::::::.: ..: :: : ::....:.:.:::..::.::: :
CCDS35 VESKSATFPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMS--
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE4 AFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKE
. : :: . : .:.: : :..: :::::::::
CCDS35 ----SGLESPTGPC--ICSLG-------NSAA---------VP---TMEGPLRRKTLLKE
420 430 440
480 490 500 510 520 530
pF1KE4 GKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEH
:.::...:::.::. : :. :.::.::::..:.:::.::: .:.::..::::.. :::::
CCDS35 GRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSIVGWMVQLPDDPEH
450 460 470 480 490 500
540 550 560 570 580
pF1KE4 PDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
::.: :.. .::: ::::.:.:..:.:: :::. ::.::. :::.:::.::
CCDS35 PDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE
510 520 530 540 550
>>CCDS55346.1 RALGPS1 gene_id:9649|Hs108|chr9 (529 aa)
initn: 2066 init1: 1189 opt: 1556 Z-score: 1606.4 bits: 307.1 E(32554): 3.7e-83
Smith-Waterman score: 1938; 56.5% identity (73.5% similar) in 577 aa overlap (5-574:5-498)
10 20 30 40 50
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLSDKGSEL-KKSFDAVVFDVLKVTPEEYAGQITL
:: .:: ..... . ::::.:: .. . .::.::::::::::::::.:.::::
CCDS55 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 MDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAE
::.::::::::.::.::::.::::.: :::.::::::::.:::::::::: :::::::::
CCDS55 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 VLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSK
.:::..: :::: ::::::.::.:::.::::::::::::::::.::::::::::.:.:::
CCDS55 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 EDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRII
:::::: :.:: ::::.: :::::::: :: :::::::..:::.::::::: ::::::::
CCDS55 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 SDLQQSCEYD-IPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASRE
.::: :: :: . ::::::::.::.::::::::::::::::::.::::.:.:: ..:.:
CCDS55 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 DLVGPEVGA-SPQSGRKSVAAEGAL---LPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNT
::.:: .:. : . .:. . . .. :: ::: :: ::: :::: :
CCDS55 DLAGPSAGSGSARFSRRPTCPDTSVAGSLP-TPPVPR------HRKSHSLGNN-------
310 320 330 340
360 370 380 390 400 410
pF1KE4 AEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAF
CCDS55 ------------------------------------------------------------
420 430 440 450 460 470
pF1KE4 ERNRLYHSLGPVTRV-ARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEG
:.::: .::: :: .::. :.. . : . .. .. :..: ::::::::::
CCDS55 -RGRLYATLGPNWRVPVRNSPRTRSCVYSPTGPCICSLGNSAAVPTMEGPLRRKTLLKEG
350 360 370 380 390 400
480 490 500 510 520 530
pF1KE4 KKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHP
.::...:::.::. : :. :.::.::::..:.::: ::..::::.. ::::::
CCDS55 RKPALSSWTRYWVILSGSTLLYYGAKSLRGTDRKH--------VSIVGWMVQLPDDPEHP
410 420 430 440 450
540 550 560 570 580
pF1KE4 DLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
:.: :.. .::: ::::.:.:..:.:: :::. ::.::. :
CCDS55 DIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQEAGAAPGPTGTDSHEVDHL
460 470 480 490 500 510
CCDS55 EGGAGKEAGPCA
520
>>CCDS55345.1 RALGPS1 gene_id:9649|Hs108|chr9 (537 aa)
initn: 2117 init1: 1189 opt: 1556 Z-score: 1606.3 bits: 307.1 E(32554): 3.7e-83
Smith-Waterman score: 1989; 57.2% identity (74.7% similar) in 577 aa overlap (5-574:5-506)
10 20 30 40 50
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLSDKGSEL-KKSFDAVVFDVLKVTPEEYAGQITL
:: .:: ..... . ::::.:: .. . .::.::::::::::::::.:.::::
CCDS55 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 MDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAE
::.::::::::.::.::::.::::.: :::.::::::::.:::::::::: :::::::::
CCDS55 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 VLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSK
.:::..: :::: ::::::.::.:::.::::::::::::::::.::::::::::.:.:::
CCDS55 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 EDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRII
:::::: :.:: ::::.: :::::::: :: :::::::..:::.::::::: ::::::::
CCDS55 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 SDLQQSCEYD-IPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASRE
.::: :: :: . ::::::::.::.::::::::::::::::::.::::.:.:: ..:.:
CCDS55 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 DLVGPEVGA-SPQSGRKSVAAEGAL---LPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNT
::.:: .:. : . .:. . . .. :: ::: :: ::: :::: :
CCDS55 DLAGPSAGSGSARFSRRPTCPDTSVAGSLP-TPPVPR------HRKSHSLGNN-------
310 320 330 340
360 370 380 390 400 410
pF1KE4 AEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAF
CCDS55 ------------------------------------------------------------
420 430 440 450 460 470
pF1KE4 ERNRLYHSLGPVTRV-ARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEG
:.::: .::: :: .::. :.. . : . .. .. :..: ::::::::::
CCDS55 -RGRLYATLGPNWRVPVRNSPRTRSCVYSPTGPCICSLGNSAAVPTMEGPLRRKTLLKEG
350 360 370 380 390 400
480 490 500 510 520 530
pF1KE4 KKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHP
.::...:::.::. : :. :.::.::::..:.:::.::: .:.::..::::.. ::::::
CCDS55 RKPALSSWTRYWVILSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSIVGWMVQLPDDPEHP
410 420 430 440 450 460
540 550 560 570 580
pF1KE4 DLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
:.: :.. .::: ::::.:.:..:.:: :::. ::.::. :
CCDS55 DIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQEAGAAPGPTGTDSHEVDHL
470 480 490 500 510 520
CCDS55 EGGAGKEAGPCA
530
>>CCDS55344.1 RALGPS1 gene_id:9649|Hs108|chr9 (305 aa)
initn: 1439 init1: 1189 opt: 1471 Z-score: 1522.7 bits: 290.8 E(32554): 1.7e-78
Smith-Waterman score: 1471; 75.8% identity (91.3% similar) in 298 aa overlap (5-300:5-302)
10 20 30 40 50
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLSDKGSEL-KKSFDAVVFDVLKVTPEEYAGQITL
:: .:: ..... . ::::.:: .. . .::.::::::::::::::.:.::::
CCDS55 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 MDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAE
::.::::::::.::.::::.::::.: :::.::::::::.:::::::::: :::::::::
CCDS55 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 VLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSK
.:::..: :::: ::::::.::.:::.::::::::::::::::.::::::::::.:.:::
CCDS55 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 EDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRII
:::::: :.:: ::::.: :::::::: :: :::::::..:::.::::::: ::::::::
CCDS55 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 SDLQQSCEYD-IPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASRE
.::: :: :: . ::::::::.::.::::::::::::::::::.::::.:.:: ..:.:
CCDS55 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 DLVGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFK
::
CCDS55 DLAAM
>>CCDS42065.1 RASGRF1 gene_id:5923|Hs108|chr15 (489 aa)
initn: 370 init1: 277 opt: 442 Z-score: 459.6 bits: 94.7 E(32554): 2.8e-19
Smith-Waterman score: 442; 29.8% identity (64.4% similar) in 292 aa overlap (3-290:209-489)
10 20 30
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLS-DKG
: . . ...:: : .... ...... ..
CCDS42 SKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEI
180 190 200 210 220 230
40 50 60 70 80 90
pF1KE4 SELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAV
... .. : :. . . : : :.::.: ::: : .:. . :: : :: .: .
CCDS42 TQMAEGVKAEPFE--NHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
240 250 260 270 280 290
100 110 120 130 140 150
pF1KE4 AFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAP
:..:: .: .. ::.. . .. :. .. ... .: :.: .:.. ..:... .
CCDS42 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
300 310 320 330 340 350
160 170 180 190 200 210
pF1KE4 IFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTY
:::: ::: .:.. :. ..::. ..:.: .: ::. ... ::.::::.::.::..
CCDS42 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCD-PPCVPYLGMYLTDLAF
360 370 380 390 400 410
220 230 240 250 260 270
pF1KE4 IDSAYPS-TGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQ
:. . :. : . : : .. ....:.: : ..::. : : .: .:: . :
CCDS42 IEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTA-YKIEHQAKVTQYLLD-------Q
420 430 440 450 460
280 290 300 310 320
pF1KE4 KFVEDDN--YKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPP
.:: :.. :. ::.::: :
CCDS42 SFVMDEESLYESSLRIEPKLPT
470 480
>>CCDS45320.1 RASGRF1 gene_id:5923|Hs108|chr15 (1257 aa)
initn: 370 init1: 277 opt: 442 Z-score: 453.1 bits: 94.9 E(32554): 6.5e-19
Smith-Waterman score: 442; 29.8% identity (64.4% similar) in 292 aa overlap (3-290:977-1257)
10 20 30
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLS-DKG
: . . ...:: : .... ...... ..
CCDS45 SKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEI
950 960 970 980 990 1000
40 50 60 70 80 90
pF1KE4 SELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAV
... .. : :. . . : : :.::.: ::: : .:. . :: : :: .: .
CCDS45 TQMAEGVKAEPFE--NHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
1010 1020 1030 1040 1050 1060
100 110 120 130 140 150
pF1KE4 AFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAP
:..:: .: .. ::.. . .. :. .. ... .: :.: .:.. ..:... .
CCDS45 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
1070 1080 1090 1100 1110 1120
160 170 180 190 200 210
pF1KE4 IFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTY
:::: ::: .:.. :. ..::. ..:.: .: ::. ... ::.::::.::.::..
CCDS45 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCD-PPCVPYLGMYLTDLAF
1130 1140 1150 1160 1170 1180
220 230 240 250 260 270
pF1KE4 IDSAYPS-TGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQ
:. . :. : . : : .. ....:.: : ..::. : : .: .:: . :
CCDS45 IEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTA-YKIEHQAKVTQYLLD-------Q
1190 1200 1210 1220 1230
280 290 300 310 320
pF1KE4 KFVEDDN--YKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPP
.:: :.. :. ::.::: :
CCDS45 SFVMDEESLYESSLRIEPKLPT
1240 1250
>>CCDS10309.1 RASGRF1 gene_id:5923|Hs108|chr15 (1273 aa)
initn: 370 init1: 277 opt: 442 Z-score: 453.0 bits: 94.9 E(32554): 6.5e-19
Smith-Waterman score: 442; 29.8% identity (64.4% similar) in 292 aa overlap (3-290:993-1273)
10 20 30
pF1KE4 MDLMNGQASSVNIAATASEKSSSSESLS-DKG
: . . ...:: : .... ...... ..
CCDS10 SKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEI
970 980 990 1000 1010 1020
40 50 60 70 80 90
pF1KE4 SELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAV
... .. : :. . . : : :.::.: ::: : .:. . :: : :: .: .
CCDS10 TQMAEGVKAEPFE--NHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
1030 1040 1050 1060 1070 1080
100 110 120 130 140 150
pF1KE4 AFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAP
:..:: .: .. ::.. . .. :. .. ... .: :.: .:.. ..:... .
CCDS10 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
1090 1100 1110 1120 1130 1140
160 170 180 190 200 210
pF1KE4 IFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTY
:::: ::: .:.. :. ..::. ..:.: .: ::. ... ::.::::.::.::..
CCDS10 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCD-PPCVPYLGMYLTDLAF
1150 1160 1170 1180 1190
220 230 240 250 260 270
pF1KE4 IDSAYPS-TGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQ
:. . :. : . : : .. ....:.: : ..::. : : .: .:: . :
CCDS10 IEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTA-YKIEHQAKVTQYLLD-------Q
1200 1210 1220 1230 1240 1250
280 290 300 310 320
pF1KE4 KFVEDDN--YKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPP
.:: :.. :. ::.::: :
CCDS10 SFVMDEESLYESSLRIEPKLPT
1260 1270
>>CCDS4052.1 RASGRF2 gene_id:5924|Hs108|chr5 (1237 aa)
initn: 389 init1: 264 opt: 429 Z-score: 439.8 bits: 92.4 E(32554): 3.5e-18
Smith-Waterman score: 429; 33.5% identity (66.5% similar) in 236 aa overlap (52-286:1005-1233)
30 40 50 60 70 80
pF1KE4 SSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKK
: : ::::.: .:..: .:. . :: :
CCDS40 DQDDIHLKLEDIIQMTDCMKAECFESLSAMELAEQITLLDHVIFRSIPYEEFLGQGWMKL
980 990 1000 1010 1020 1030
90 100 110 120 130 140
pF1KE4 EKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALM
.: .: . ...:: .: :. .:.. .. ::... ... .: :.: ....
CCDS40 DKNERTPYIMKTSQHFNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVL
1040 1050 1060 1070 1080 1090
150 160 170 180 190 200
pF1KE4 AVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPY
..:.:. . :.:: :::: .:.. :. ..::. ..:.: .: ::. ... . : .::
CCDS40 EITSALNRSAIYRLKKTWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCN-PPAVPY
1100 1110 1120 1130 1140 1150
210 220 230 240 250 260
pF1KE4 LGIYLSDLTYIDSAYPS-TGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYL
::.::.::..:. . :. : : : .. ....:.: : ..::. : : :.: .::
CCDS40 LGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTS-YRIDHQPKVAQYL
1160 1170 1180 1190 1200 1210
270 280 290 300 310 320
pF1KE4 NSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEG
. . : . :: :.:::::::
CCDS40 LDKDLIID-----EDTLYELSLKIEPRLPA
1220 1230
583 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:10:55 2016 done: Sat Nov 5 17:10:55 2016
Total Scan time: 3.680 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]