Result of FASTA (omim) for
pFN21AE4570
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4570, 732 aa
1>>>pF1KE4570 732 - 732 aa - 732 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7579+/-0.000372; mu= 16.6153+/- 0.023
mean_var=66.2169+/-13.192, 0's: 0 Z-trim(112.0): 17 B-trim: 19 in 1/54
Lambda= 0.157612
statistics sampled from 20741 (20755) to 20741 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.243), width: 16
Scan time: 11.390
The best scores are: opt bits E(85289)
NP_001001438 (OMIM: 600909,616509) lanosterol synt ( 732) 5154 1181.4 0
XP_016883835 (OMIM: 600909,616509) PREDICTED: lano ( 732) 5154 1181.4 0
NP_002331 (OMIM: 600909,616509) lanosterol synthas ( 732) 5154 1181.4 0
NP_001138909 (OMIM: 600909,616509) lanosterol synt ( 652) 4595 1054.3 0
NP_001138908 (OMIM: 600909,616509) lanosterol synt ( 721) 4143 951.5 0
XP_016883836 (OMIM: 600909,616509) PREDICTED: lano ( 721) 4143 951.5 0
XP_011527867 (OMIM: 600909,616509) PREDICTED: lano ( 742) 3902 896.8 0
XP_011527866 (OMIM: 600909,616509) PREDICTED: lano ( 742) 3902 896.8 0
XP_016883837 (OMIM: 600909,616509) PREDICTED: lano ( 710) 3891 894.2 0
XP_011527869 (OMIM: 600909,616509) PREDICTED: lano ( 710) 3891 894.2 0
XP_011527868 (OMIM: 600909,616509) PREDICTED: lano ( 731) 2891 666.9 8.2e-191
XP_006724067 (OMIM: 600909,616509) PREDICTED: lano ( 414) 2789 643.6 4.7e-184
>>NP_001001438 (OMIM: 600909,616509) lanosterol synthase (732 aa)
initn: 5154 init1: 5154 opt: 5154 Z-score: 6327.7 bits: 1181.4 E(85289): 0
Smith-Waterman score: 5154; 99.9% identity (100.0% similar) in 732 aa overlap (1-732:1-732)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_001 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
670 680 690 700 710 720
730
pF1KE4 QLYPERALAGHP
::::::::::::
NP_001 QLYPERALAGHP
730
>>XP_016883835 (OMIM: 600909,616509) PREDICTED: lanoster (732 aa)
initn: 5154 init1: 5154 opt: 5154 Z-score: 6327.7 bits: 1181.4 E(85289): 0
Smith-Waterman score: 5154; 99.9% identity (100.0% similar) in 732 aa overlap (1-732:1-732)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
670 680 690 700 710 720
730
pF1KE4 QLYPERALAGHP
::::::::::::
XP_016 QLYPERALAGHP
730
>>NP_002331 (OMIM: 600909,616509) lanosterol synthase is (732 aa)
initn: 5154 init1: 5154 opt: 5154 Z-score: 6327.7 bits: 1181.4 E(85289): 0
Smith-Waterman score: 5154; 99.9% identity (100.0% similar) in 732 aa overlap (1-732:1-732)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_002 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
670 680 690 700 710 720
730
pF1KE4 QLYPERALAGHP
::::::::::::
NP_002 QLYPERALAGHP
730
>>NP_001138909 (OMIM: 600909,616509) lanosterol synthase (652 aa)
initn: 4595 init1: 4595 opt: 4595 Z-score: 5641.5 bits: 1054.3 E(85289): 0
Smith-Waterman score: 4595; 99.8% identity (100.0% similar) in 652 aa overlap (81-732:1-652)
60 70 80 90 100 110
pF1KE4 LEAYALGLDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLI
::::::::::::::::::::::::::::::
NP_001 MTFYVGLQAEDGHWTGDYGGPLFLLPGLLI
10 20 30
120 130 140 150 160 170
pF1KE4 TCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 PDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLW
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE4 CHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHS
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE4 WLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 DGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSC
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE4 LQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEK
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE4 CPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTY
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE4 VECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTW
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE4 FGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIH
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_001 FGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIH
520 530 540 550 560 570
660 670 680 690 700 710
pF1KE4 NTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNI
580 590 600 610 620 630
720 730
pF1KE4 FPIWALGRFSQLYPERALAGHP
::::::::::::::::::::::
NP_001 FPIWALGRFSQLYPERALAGHP
640 650
>>NP_001138908 (OMIM: 600909,616509) lanosterol synthase (721 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 5085.4 bits: 951.5 E(85289): 0
Smith-Waterman score: 5038; 98.4% identity (98.5% similar) in 732 aa overlap (1-732:1-721)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
:::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 AGYREEIVRYLR-----------HIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_001 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
650 660 670 680 690 700
730
pF1KE4 QLYPERALAGHP
::::::::::::
NP_001 QLYPERALAGHP
710 720
>>XP_016883836 (OMIM: 600909,616509) PREDICTED: lanoster (721 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 5085.4 bits: 951.5 E(85289): 0
Smith-Waterman score: 5038; 98.4% identity (98.5% similar) in 732 aa overlap (1-732:1-721)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
:::::::::::: :::::::::::::::::::::::::::::::::::::
XP_016 AGYREEIVRYLR-----------HIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
650 660 670 680 690 700
730
pF1KE4 QLYPERALAGHP
::::::::::::
XP_016 QLYPERALAGHP
710 720
>>XP_011527867 (OMIM: 600909,616509) PREDICTED: lanoster (742 aa)
initn: 3891 init1: 3891 opt: 3902 Z-score: 4789.0 bits: 896.8 E(85289): 0
Smith-Waterman score: 5124; 98.5% identity (98.7% similar) in 742 aa overlap (1-732:1-742)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590
pF1KE4 LKYFHKRFPEHRAAEIR----------ETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTW
::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_011 LKYFHKRFPEHRAAEIRMFTGPISCSRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTW
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE4 FGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIH
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
XP_011 FGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIH
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE4 NTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNI
670 680 690 700 710 720
720 730
pF1KE4 FPIWALGRFSQLYPERALAGHP
::::::::::::::::::::::
XP_011 FPIWALGRFSQLYPERALAGHP
730 740
>>XP_011527866 (OMIM: 600909,616509) PREDICTED: lanoster (742 aa)
initn: 3891 init1: 3891 opt: 3902 Z-score: 4789.0 bits: 896.8 E(85289): 0
Smith-Waterman score: 5124; 98.5% identity (98.7% similar) in 742 aa overlap (1-732:1-742)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590
pF1KE4 LKYFHKRFPEHRAAEIR----------ETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTW
::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_011 LKYFHKRFPEHRAAEIRMFTGPISCSRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTW
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE4 FGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIH
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
XP_011 FGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIH
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE4 NTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNI
670 680 690 700 710 720
720 730
pF1KE4 FPIWALGRFSQLYPERALAGHP
::::::::::::::::::::::
XP_011 FPIWALGRFSQLYPERALAGHP
730 740
>>XP_016883837 (OMIM: 600909,616509) PREDICTED: lanoster (710 aa)
initn: 4982 init1: 3891 opt: 3891 Z-score: 4775.8 bits: 894.2 E(85289): 0
Smith-Waterman score: 4942; 96.9% identity (97.0% similar) in 732 aa overlap (1-732:1-710)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::: :::::::::::::::::::::
XP_016 LKYFHKRFPEHRAAEIR----------------------SWGVCFTYGTWFGLEAFACMG
550 560 570
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
640 650 660 670 680 690
730
pF1KE4 QLYPERALAGHP
::::::::::::
XP_016 QLYPERALAGHP
700 710
>>XP_011527869 (OMIM: 600909,616509) PREDICTED: lanoster (710 aa)
initn: 4982 init1: 3891 opt: 3891 Z-score: 4775.8 bits: 894.2 E(85289): 0
Smith-Waterman score: 4942; 96.9% identity (97.0% similar) in 732 aa overlap (1-732:1-710)
10 20 30 40 50 60
pF1KE4 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
::::::::::::::::: :::::::::::::::::::::
XP_011 LKYFHKRFPEHRAAEIR----------------------SWGVCFTYGTWFGLEAFACMG
550 560 570
610 620 630 640 650 660
pF1KE4 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLM
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE4 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
640 650 660 670 680 690
730
pF1KE4 QLYPERALAGHP
::::::::::::
XP_011 QLYPERALAGHP
700 710
732 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:51:34 2016 done: Sat Nov 5 23:51:36 2016
Total Scan time: 11.390 Total Display time: 0.230
Function used was FASTA [36.3.4 Apr, 2011]