FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1311, 469 aa
  1>>>pF1KE1311 469 - 469 aa - 469 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0456+/-0.000392; mu= 15.0637+/- 0.024
 mean_var=94.9913+/-18.606, 0's: 0 Z-trim(114.7): 21  B-trim: 555 in 1/52
 Lambda= 0.131593
 statistics sampled from 24646 (24667) to 24646 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.289), width:  16
 Scan time: 10.030

The best scores are:                                      opt bits E(85289)
NP_055271 (OMIM: 608610) programmed cell death pro ( 469) 3071 593.5 4.2e-169
NP_663314 (OMIM: 608610) programmed cell death pro ( 458) 2973 574.9 1.6e-163
NP_001186421 (OMIM: 608610) programmed cell death  ( 455) 2885 558.2 1.7e-158


>>NP_055271 (OMIM: 608610) programmed cell death protein  (469 aa)
 initn: 3071 init1: 3071 opt: 3071  Z-score: 3157.0  bits: 593.5 E(85289): 4.2e-169
Smith-Waterman score: 3071; 99.6% identity (99.8% similar) in 469 aa overlap (1-469:1-469)

               10        20        30        40        50        60
pF1KE1 MDVENEQILNVNPADPDNLSDSLFSGDEENAGTEEVKNEINGNWISAYSINEARINAKAK
       :::::::::::::::::::::::::::::::::::.::::::::::: ::::::::::::
NP_055 MDVENEQILNVNPADPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
              370       380       390       400       410       420

              430       440       450       460         
pF1KE1 HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
              430       440       450       460         

>>NP_663314 (OMIM: 608610) programmed cell death protein  (458 aa)
 initn: 2973 init1: 2973 opt: 2973  Z-score: 3056.6  bits: 574.9 E(85289): 1.6e-163
Smith-Waterman score: 2973; 99.6% identity (99.8% similar) in 454 aa overlap (16-469:5-458)

               10        20        30        40        50        60
pF1KE1 MDVENEQILNVNPADPDNLSDSLFSGDEENAGTEEVKNEINGNWISAYSINEARINAKAK
                      ::::::::::::::::::::.::::::::::: ::::::::::::
NP_663            MTKYPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAK
                          10        20        30        40         

               70        80        90       100       110       120
pF1KE1 RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
      50        60        70        80        90       100         

              130       140       150       160       170       180
pF1KE1 KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
     110       120       130       140       150       160         

              190       200       210       220       230       240
pF1KE1 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
     170       180       190       200       210       220         

              250       260       270       280       290       300
pF1KE1 DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
     230       240       250       260       270       280         

              310       320       330       340       350       360
pF1KE1 LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
     290       300       310       320       330       340         

              370       380       390       400       410       420
pF1KE1 HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
     350       360       370       380       390       400         

              430       440       450       460         
pF1KE1 HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
     410       420       430       440       450        

>>NP_001186421 (OMIM: 608610) programmed cell death prot  (455 aa)
 initn: 2885 init1: 2885 opt: 2885  Z-score: 2966.3  bits: 558.2 E(85289): 1.7e-158
Smith-Waterman score: 2937; 96.6% identity (96.8% similar) in 469 aa overlap (1-469:1-455)

               10        20        30        40        50        60
pF1KE1 MDVENEQILNVNPADPDNLSDSLFSGDEENAGTEEVKNEINGNWISAYSINEARINAKAK
       ::::::::::::::              :::::::.::::::::::: ::::::::::::
NP_001 MDVENEQILNVNPA--------------ENAGTEEIKNEINGNWISASSINEARINAKAK
               10                      20        30        40      

               70        80        90       100       110       120
pF1KE1 RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
         50        60        70        80        90       100      

              130       140       150       160       170       180
pF1KE1 KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
        110       120       130       140       150       160      

              190       200       210       220       230       240
pF1KE1 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
        170       180       190       200       210       220      

              250       260       270       280       290       300
pF1KE1 DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
        230       240       250       260       270       280      

              310       320       330       340       350       360
pF1KE1 LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
        290       300       310       320       330       340      

              370       380       390       400       410       420
pF1KE1 HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
        350       360       370       380       390       400      

              430       440       450       460         
pF1KE1 HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
        410       420       430       440       450     




469 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 00:29:54 2016 done: Mon Nov  7 00:29:56 2016
 Total Scan time: 10.030 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]