Result of FASTA (omim) for
pFN21AE4375
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4375, 395 aa
1>>>pF1KE4375 395 - 395 aa - 395 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6316+/-0.000413; mu= 15.1324+/- 0.026
mean_var=70.0061+/-13.993, 0's: 0 Z-trim(111.8): 6 B-trim: 154 in 1/53
Lambda= 0.153287
statistics sampled from 20530 (20534) to 20530 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.241), width: 16
Scan time: 5.810
The best scores are: opt bits E(85289)
XP_005269899 (OMIM: 250850,610550) PREDICTED: S-ad ( 395) 2662 598.0 1.2e-170
NP_000420 (OMIM: 250850,610550) S-adenosylmethioni ( 395) 2662 598.0 1.2e-170
NP_005902 (OMIM: 601468) S-adenosylmethionine synt ( 395) 2311 520.4 2.9e-147
XP_005269900 (OMIM: 250850,610550) PREDICTED: S-ad ( 354) 2013 454.5 1.8e-127
>>XP_005269899 (OMIM: 250850,610550) PREDICTED: S-adenos (395 aa)
initn: 2662 init1: 2662 opt: 2662 Z-score: 3184.3 bits: 598.0 E(85289): 1.2e-170
Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KE4 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
310 320 330 340 350 360
370 380 390
pF1KE4 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
:::::::::::::::::::::::::::::::::::
XP_005 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
370 380 390
>>NP_000420 (OMIM: 250850,610550) S-adenosylmethionine s (395 aa)
initn: 2662 init1: 2662 opt: 2662 Z-score: 3184.3 bits: 598.0 E(85289): 1.2e-170
Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KE4 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
310 320 330 340 350 360
370 380 390
pF1KE4 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
:::::::::::::::::::::::::::::::::::
NP_000 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
370 380 390
>>NP_005902 (OMIM: 601468) S-adenosylmethionine synthase (395 aa)
initn: 2339 init1: 2311 opt: 2311 Z-score: 2764.8 bits: 520.4 E(85289): 2.9e-147
Smith-Waterman score: 2311; 84.3% identity (95.4% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KE4 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
::: ..:. . . ::.:.:::::::::::::::::::::::::::.:::.::::::::
NP_005 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
::::.:: ::::: : ::::.:::...::::::::.::::.::::::::::::::::::
NP_005 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
:::::::::.::::::::::::::::::::::::.:::::::..:.:::.: ::::::::
NP_005 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
::::::::::: :::.:.:.:::::::::.:.. :.::: ::::.::.::::::::::::
NP_005 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
.:::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_005 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
:::::::.::::::::::::::::..::::::: ::::::.:::::..:.::::::::::
NP_005 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
310 320 330 340 350 360
370 380 390
pF1KE4 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
::::::::::::.:: ::::::. ::::::.:: .
NP_005 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
370 380 390
>>XP_005269900 (OMIM: 250850,610550) PREDICTED: S-adenos (354 aa)
initn: 2000 init1: 2000 opt: 2013 Z-score: 2409.4 bits: 454.5 E(85289): 1.8e-127
Smith-Waterman score: 2300; 89.6% identity (89.6% similar) in 395 aa overlap (1-395:1-354)
10 20 30 40 50 60
pF1KE4 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVAC----
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
:::::::::::::::::::::::
XP_005 -------------------------------------GFDFKTCNVLVALEQQSPDIAQC
60 70
130 140 150 160 170 180
pF1KE4 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE4 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE4 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE4 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
260 270 280 290 300 310
370 380 390
pF1KE4 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
:::::::::::::::::::::::::::::::::::
XP_005 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
320 330 340 350
395 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:39:19 2016 done: Mon Nov 7 17:39:20 2016
Total Scan time: 5.810 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]