Result of FASTA (omim) for
pFN21AB7985
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7985, 431 aa
1>>>pF1KB7985 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0312+/-0.000401; mu= -4.6248+/- 0.025
mean_var=249.1894+/-51.791, 0's: 0 Z-trim(120.5): 25 B-trim: 368 in 2/53
Lambda= 0.081247
statistics sampled from 35751 (35776) to 35751 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.419), width: 16
Scan time: 9.550
The best scores are: opt bits E(85289)
NP_001027451 (OMIM: 107580,113620) transcription f ( 431) 2929 356.3 8.6e-98
NP_001035890 (OMIM: 107580,113620) transcription f ( 433) 2872 349.6 8.9e-96
NP_003211 (OMIM: 107580,113620) transcription fact ( 437) 2872 349.6 9e-96
XP_006715238 (OMIM: 107580,113620) PREDICTED: tran ( 482) 2872 349.7 9.7e-96
XP_016866721 (OMIM: 107580,113620) PREDICTED: tran ( 519) 2872 349.7 1e-95
XP_011513135 (OMIM: 107580,113620) PREDICTED: tran ( 387) 2384 292.4 1.3e-78
XP_011513139 (OMIM: 169100,601601,617035) PREDICTE ( 469) 2046 252.8 1.3e-66
XP_016866723 (OMIM: 169100,601601,617035) PREDICTE ( 503) 2046 252.9 1.4e-66
XP_016866722 (OMIM: 169100,601601,617035) PREDICTE ( 515) 2046 252.9 1.4e-66
NP_003212 (OMIM: 169100,601601,617035) transcripti ( 460) 2000 247.4 5.5e-65
NP_848643 (OMIM: 614428) transcription factor AP-2 ( 442) 1539 193.4 9.8e-49
NP_003213 (OMIM: 601602) transcription factor AP-2 ( 450) 1468 185.1 3.2e-46
XP_016866724 (OMIM: 169100,601601,617035) PREDICTE ( 307) 1405 177.6 3.9e-44
NP_758438 (OMIM: 610161) transcription factor AP-2 ( 452) 1181 151.4 4.3e-36
XP_016856628 (OMIM: 614428) PREDICTED: transcripti ( 356) 1082 139.8 1.1e-32
>>NP_001027451 (OMIM: 107580,113620) transcription facto (431 aa)
initn: 2929 init1: 2929 opt: 2929 Z-score: 1876.6 bits: 356.3 E(85289): 8.6e-98
Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSKSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 ILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNA
370 380 390 400 410 420
430
pF1KB7 KSSDKEEKHRK
:::::::::::
NP_001 KSSDKEEKHRK
430
>>NP_001035890 (OMIM: 107580,113620) transcription facto (433 aa)
initn: 2872 init1: 2872 opt: 2872 Z-score: 1840.5 bits: 349.6 E(85289): 8.9e-96
Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 422 aa overlap (10-431:12-433)
10 20 30 40 50
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSILAKMGDWQDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 IYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 RDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 SNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 NASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 GYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 NPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDN
370 380 390 400 410 420
420 430
pF1KB7 NAKSSDKEEKHRK
:::::::::::::
NP_001 NAKSSDKEEKHRK
430
>>NP_003211 (OMIM: 107580,113620) transcription factor A (437 aa)
initn: 2872 init1: 2872 opt: 2872 Z-score: 1840.4 bits: 349.6 E(85289): 9e-96
Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 422 aa overlap (10-431:16-437)
10 20 30 40 50
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPP
:::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 PYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 LDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 SLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 PECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 ARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 NSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNS
370 380 390 400 410 420
420 430
pF1KB7 HTDNNAKSSDKEEKHRK
:::::::::::::::::
NP_003 HTDNNAKSSDKEEKHRK
430
>>XP_006715238 (OMIM: 107580,113620) PREDICTED: transcri (482 aa)
initn: 2872 init1: 2872 opt: 2872 Z-score: 1839.8 bits: 349.7 E(85289): 9.7e-96
Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 422 aa overlap (10-431:61-482)
10 20 30
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPL
::::::::::::::::::::::::::::::
XP_006 SACRAESPTSARTRSQAAPTRYARPPLHPEDRHDGTSNGTARLPQLGTVGQSPYTSAPPL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB7 SHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQES
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB7 GLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB7 GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB7 KYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAN
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB7 VTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQIC
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB7 KEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEA
400 410 420 430 440 450
400 410 420 430
pF1KB7 LKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK
::::::::::::::::::::::::::::::::
XP_006 LKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK
460 470 480
>>XP_016866721 (OMIM: 107580,113620) PREDICTED: transcri (519 aa)
initn: 2872 init1: 2872 opt: 2872 Z-score: 1839.3 bits: 349.7 E(85289): 1e-95
Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 422 aa overlap (10-431:98-519)
10 20 30
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPL
::::::::::::::::::::::::::::::
XP_016 LCGAGTAAGGVNSWASAHASAGSNPALYDQDRHDGTSNGTARLPQLGTVGQSPYTSAPPL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB7 SHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQES
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB7 GLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDP
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB7 GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTS
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB7 KYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAN
310 320 330 340 350 360
280 290 300 310 320 330
pF1KB7 VTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQIC
370 380 390 400 410 420
340 350 360 370 380 390
pF1KB7 KEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEA
430 440 450 460 470 480
400 410 420 430
pF1KB7 LKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK
::::::::::::::::::::::::::::::::
XP_016 LKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK
490 500 510
>>XP_011513135 (OMIM: 107580,113620) PREDICTED: transcri (387 aa)
initn: 2384 init1: 2384 opt: 2384 Z-score: 1532.1 bits: 292.4 E(85289): 1.3e-78
Smith-Waterman score: 2384; 100.0% identity (100.0% similar) in 356 aa overlap (76-431:32-387)
50 60 70 80 90 100
pF1KB7 DFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTH
::::::::::::::::::::::::::::::
XP_011 RRQVATQLFMTRTVTTAPATGRHGCPSWALLNPLHAQPQPQHPGWPGQRQSQESGLLHTH
10 20 30 40 50 60
110 120 130 140 150 160
pF1KB7 RGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPD
70 80 90 100 110 120
170 180 190 200 210 220
pF1KB7 QTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTV
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB7 AEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTS
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB7 LVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDL
250 260 270 280 290 300
350 360 370 380 390 400
pF1KB7 LAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDK
310 320 330 340 350 360
410 420 430
pF1KB7 MYLSNNPNSHTDNNAKSSDKEEKHRK
::::::::::::::::::::::::::
XP_011 MYLSNNPNSHTDNNAKSSDKEEKHRK
370 380
>>XP_011513139 (OMIM: 169100,601601,617035) PREDICTED: t (469 aa)
initn: 1966 init1: 1259 opt: 2046 Z-score: 1316.7 bits: 252.8 E(85289): 1.3e-66
Smith-Waterman score: 2063; 71.8% identity (87.1% similar) in 451 aa overlap (1-431:28-469)
10 20 30
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPY
::::..:.::::::. . ..:: :::.:.:.::
XP_011 MHSPPRDQAAIMLWKLVENVKYEDIYEMLVHTYSSMDRHDGVPSHSSRLSQLGSVSQGPY
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 TSAPPLSHTPNADFQPPYFPPPYQPI-YPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPG
.:::::::::..:::::::::::::. : ::::::::::::::::::: ::: ::: : :
XP_011 SSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLH-QPQ-QHP-W-G
70 80 90 100 110
100 110 120 130 140
pF1KB7 QRQSQESG-----LLHTHRGLPHQLSGLDPRRDY---RRHEDLLHGPH-ALSSGLGD-LS
::: :: : :: :. ::::::::::: :: . :::. : .:..:.:: ::
XP_011 QRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLS
120 130 140 150 160 170
150 160 170 180 190
pF1KB7 IHSLPH-AIEEVPHVEDP---GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGV
.:.: : ..:.: ::: :.:. ::.:::: :: ..:... .:::...::.
XP_011 LHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVP-----PKSVTSLMMNKDGFLGGM
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB7 -VNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGR
:: .:::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 SVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGR
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB7 SLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNR
::::.:.::::::::::::::::::::::::::::::::::::.::::::::::.:.:::
XP_011 SLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNR
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB7 QHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLIS
::.::.. .::::::::::.::::::::::::.:.:::::.::::::::::::::.::.
XP_011 QHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLIT
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB7 HGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNP-NSHTDNN---AKSSDKEEKHRK
::::.::.:::.::::::::::::.::::.:.:. : ::... .:..::::::::
XP_011 HGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRK
420 430 440 450 460
>>XP_016866723 (OMIM: 169100,601601,617035) PREDICTED: t (503 aa)
initn: 1942 init1: 1259 opt: 2046 Z-score: 1316.3 bits: 252.9 E(85289): 1.4e-66
Smith-Waterman score: 2063; 71.8% identity (87.1% similar) in 451 aa overlap (1-431:62-503)
10 20 30
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQ
::::..:.::::::. . ..:: :::.:.:
XP_016 SGSLWRMSSTKISMSTQGDQVLRIREVSLQMLVHTYSSMDRHDGVPSHSSRLSQLGSVSQ
40 50 60 70 80 90
40 50 60 70 80
pF1KB7 SPYTSAPPLSHTPNADFQPPYFPPPYQPI-YPQSQDPYSHVNDPYSLNPLHAQPQPQHPG
.::.:::::::::..:::::::::::::. : ::::::::::::::::::: ::: :::
XP_016 GPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLH-QPQ-QHP-
100 110 120 130 140
90 100 110 120 130 140
pF1KB7 WPGQRQSQESG-----LLHTHRGLPHQLSGLDPRRDY---RRHEDLLHGPH-ALSSGLGD
: :::: :: : :: :. ::::::::::: :: . :::. : .:..:.::
XP_016 W-GQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGD
150 160 170 180 190 200
150 160 170 180 190
pF1KB7 -LSIHSLPH-AIEEVPHVEDP---GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLF
::.:.: : ..:.: ::: :.:. ::.:::: :: ..:... .:::...
XP_016 SLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVP-----PKSVTSLMMNKDGFL
210 220 230 240 250 260
200 210 220 230 240 250
pF1KB7 GGV-VNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKN
::. :: .:::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_016 GGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKN
270 280 290 300 310 320
260 270 280 290 300 310
pF1KB7 GGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEF
:::::::.:.::::::::::::::::::::::::::::::::::::.::::::::::.:.
XP_016 GGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEY
330 340 350 360 370 380
320 330 340 350 360 370
pF1KB7 LNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFN
:::::.::.. .::::::::::.::::::::::::.:.:::::.::::::::::::::.
XP_016 LNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFS
390 400 410 420 430 440
380 390 400 410 420 430
pF1KB7 LISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNP-NSHTDNN---AKSSDKEEKHR
::.::::.::.:::.::::::::::::.::::.:.:. : ::... .:..:::::::
XP_016 LITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHR
450 460 470 480 490 500
pF1KB7 K
:
XP_016 K
>>XP_016866722 (OMIM: 169100,601601,617035) PREDICTED: t (515 aa)
initn: 1942 init1: 1259 opt: 2046 Z-score: 1316.1 bits: 252.9 E(85289): 1.4e-66
Smith-Waterman score: 2063; 71.8% identity (87.1% similar) in 451 aa overlap (1-431:74-515)
10 20 30
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQ
::::..:.::::::. . ..:: :::.:.:
XP_016 SGSLWRMSSTKISMSTQGDQVLRIREVSLQMLVHTYSSMDRHDGVPSHSSRLSQLGSVSQ
50 60 70 80 90 100
40 50 60 70 80
pF1KB7 SPYTSAPPLSHTPNADFQPPYFPPPYQPI-YPQSQDPYSHVNDPYSLNPLHAQPQPQHPG
.::.:::::::::..:::::::::::::. : ::::::::::::::::::: ::: :::
XP_016 GPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLH-QPQ-QHP-
110 120 130 140 150 160
90 100 110 120 130 140
pF1KB7 WPGQRQSQESG-----LLHTHRGLPHQLSGLDPRRDY---RRHEDLLHGPH-ALSSGLGD
: :::: :: : :: :. ::::::::::: :: . :::. : .:..:.::
XP_016 W-GQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGD
170 180 190 200 210
150 160 170 180 190
pF1KB7 -LSIHSLPH-AIEEVPHVEDP---GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLF
::.:.: : ..:.: ::: :.:. ::.:::: :: ..:... .:::...
XP_016 SLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVP-----PKSVTSLMMNKDGFL
220 230 240 250 260 270
200 210 220 230 240 250
pF1KB7 GGV-VNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKN
::. :: .:::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_016 GGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKN
280 290 300 310 320 330
260 270 280 290 300 310
pF1KB7 GGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEF
:::::::.:.::::::::::::::::::::::::::::::::::::.::::::::::.:.
XP_016 GGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEY
340 350 360 370 380 390
320 330 340 350 360 370
pF1KB7 LNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFN
:::::.::.. .::::::::::.::::::::::::.:.:::::.::::::::::::::.
XP_016 LNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFS
400 410 420 430 440 450
380 390 400 410 420 430
pF1KB7 LISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNP-NSHTDNN---AKSSDKEEKHR
::.::::.::.:::.::::::::::::.::::.:.:. : ::... .:..:::::::
XP_016 LITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHR
460 470 480 490 500 510
pF1KB7 K
:
XP_016 K
>>NP_003212 (OMIM: 169100,601601,617035) transcription f (460 aa)
initn: 1920 init1: 1259 opt: 2000 Z-score: 1287.7 bits: 247.4 E(85289): 5.5e-65
Smith-Waterman score: 2017; 71.9% identity (86.9% similar) in 442 aa overlap (10-431:28-460)
10 20 30 40
pF1KB7 MLVHSFSAMDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHT
:::::. . ..:: :::.:.:.::.::::::::
NP_003 MHSPPRDQAAIMLWKLVENVKYEDIYEDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 PNADFQPPYFPPPYQPI-YPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESG-
:..:::::::::::::. : ::::::::::::::::::: ::: ::: : :::: :: :
NP_003 PSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLH-QPQ-QHP-W-GQRQRQEVGS
70 80 90 100 110
110 120 130 140 150
pF1KB7 ----LLHTHRGLPHQLSGLDPRRDY---RRHEDLLHGPH-ALSSGLGD-LSIHSLPH-AI
:: :. ::::::::::: :: . :::. : .:..:.:: ::.:.: : ..
NP_003 EAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGM
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 EEVPHVEDP---GINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGV-VNPNEVFC
:.: ::: :.:. ::.:::: :: ..:... .:::...::. :: .::::
NP_003 EDVQSVEDANNSGMNLLDQSVIKKVPVP-----PKSVTSLMMNKDGFLGGMSVNTGEVFC
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 SVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKI
:::::::::::::::::::.:::::::::::::::::::::::::::::::::::.:.::
NP_003 SVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKI
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB7 GLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQV
::::::::::::::::::::::::::::::::::.::::::::::.:.:::::.::..
NP_003 GLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLH
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB7 TRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVC
.::::::::::.::::::::::::.:.:::::.::::::::::::::.::.::::.::.:
NP_003 SRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAIC
360 370 380 390 400 410
390 400 410 420 430
pF1KB7 AAVTALQNYLTEALKAMDKMYLSNNP-NSHTDNN---AKSSDKEEKHRK
::.::::::::::::.::::.:.:. : ::... .:..::::::::
NP_003 AALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRK
420 430 440 450 460
431 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:28:16 2016 done: Sat Nov 5 21:28:17 2016
Total Scan time: 9.550 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]