Result of FASTA (ccds) for
pFN21AB7594
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7594, 291 aa
1>>>pF1KB7594 291 - 291 aa - 291 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5463+/-0.000821; mu= 4.2043+/- 0.050
mean_var=270.5164+/-54.335, 0's: 0 Z-trim(116.6): 147 B-trim: 0 in 0/53
Lambda= 0.077979
statistics sampled from 17057 (17221) to 17057 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.529), width: 16
Scan time: 3.080
The best scores are: opt bits E(32554)
CCDS34288.1 TLX3 gene_id:30012|Hs108|chr5 ( 291) 1984 235.4 3.8e-62
CCDS1947.1 TLX2 gene_id:3196|Hs108|chr2 ( 284) 1016 126.5 2.3e-29
CCDS7510.1 TLX1 gene_id:3195|Hs108|chr10 ( 330) 852 108.1 9e-24
CCDS55725.1 TLX1 gene_id:3195|Hs108|chr10 ( 257) 512 69.7 2.5e-12
>>CCDS34288.1 TLX3 gene_id:30012|Hs108|chr5 (291 aa)
initn: 1984 init1: 1984 opt: 1984 Z-score: 1229.2 bits: 235.4 E(32554): 3.8e-62
Smith-Waterman score: 1984; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
250 260 270 280 290
>>CCDS1947.1 TLX2 gene_id:3196|Hs108|chr2 (284 aa)
initn: 1063 init1: 770 opt: 1016 Z-score: 640.8 bits: 126.5 E(32554): 2.3e-29
Smith-Waterman score: 1102; 64.1% identity (80.1% similar) in 287 aa overlap (10-290:12-280)
10 20 30 40 50
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAP--RGPDGASYLGGPPGGRPGATY
:: ::::::::::::..:. .. :: .: . :. :: ::.
CCDS19 MEPGMLGPHNLPH-HEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASG
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 PSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPT
. :: : ::. :: .:. :.:::::::::::: :::: .: ::.:. :.
CCDS19 YG-PA---GSLAPL--PGSSGVG----PGGVIRVPAHRPLP--VPPPAGGA-PAVPG-PS
60 70 80 90 100
120 130 140 150 160 170
pF1KB7 ----VSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTS
...:.::.::::.:.:::.:::.::: :.::. ::::::::::::::::::::::
CCDS19 GLGGAGGLAGLTFPWMDSGRRFAKDRLTAA--LSPFSGTRRIGHPYQNRTPPKRKKPRTS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 FSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAE
::: :. :::.:: :::::::::::::::.:.::::::::::::::::::::::::::::
CCDS19 FSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 RQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
:..:.::.:.::.::. . : . :::::::::::::::::::: ::. :: .:..:
CCDS19 RHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLAS
230 240 250 260 270 280
CCDS19 VV
>>CCDS7510.1 TLX1 gene_id:3195|Hs108|chr10 (330 aa)
initn: 1111 init1: 792 opt: 852 Z-score: 540.3 bits: 108.1 E(32554): 9e-24
Smith-Waterman score: 1127; 59.6% identity (71.7% similar) in 332 aa overlap (11-290:10-325)
10 20 30 40
pF1KB7 MEAPASAQTPHP-H-EPISFGIDQILNSPDQDS--APAPRGPDGASYLG-----------
:: : :::::::::::::::: . .:: : :: ::
CCDS75 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGG
10 20 30 40 50
50 60 70 80
pF1KB7 -------GPPG-GRPGATYPSLPASFAGLGA-----PFEDAGSYSVNLSLA--P------
: : : :. :. :.. :: :. :. .:::.::..:: :
CCDS75 GGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGG
60 70 80 90 100 110
90 100 110 120
pF1KB7 -----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWM
:::::::::::: ::: : :: ..::..::::. :..: ::.::::
CCDS75 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 ESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQ
::.::..::::: :::::::::::.:::::::.:.::::::::::::
CCDS75 ESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQ
180 190 200 210 220
190 200 210 220 230 240
pF1KB7 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAF
:::::::::::::.::::::::::::::::::::::::::::::::::.:..::::..::
CCDS75 KYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAF
230 240 250 260 270 280
250 260 270 280 290
pF1KB7 QKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
:::: . . ::::.:::::::::::::: .::.:. .:::.
CCDS75 QKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
290 300 310 320 330
>>CCDS55725.1 TLX1 gene_id:3195|Hs108|chr10 (257 aa)
initn: 687 init1: 460 opt: 512 Z-score: 334.9 bits: 69.7 E(32554): 2.5e-12
Smith-Waterman score: 787; 56.4% identity (67.8% similar) in 264 aa overlap (11-222:10-257)
10 20 30 40
pF1KB7 MEAPASAQTPHP-H-EPISFGIDQILNSPDQDS--APAPRGPDGA-----------SYLG
:: : :::::::::::::::: . .:: : :: .: :
CCDS55 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGG
10 20 30 40 50
50 60 70 80
pF1KB7 GPPGGRPGA----TY----PSLPASFAGLGA-----PFEDAGSYSVNLSLA--P------
: .. :: .: :. :.. :: :. :. .:::.::..:: :
CCDS55 GGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGG
60 70 80 90 100 110
90 100 110 120
pF1KB7 -----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWM
:::::::::::: ::: : :: ..::..::::. :..: ::.::::
CCDS55 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 ESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQ
::.::..::::: :::::::::::.:::::::.:.::::::::::::
CCDS55 ESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQ
180 190 200 210 220
190 200 210 220 230 240
pF1KB7 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAF
:::::::::::::.::::::::::::::::::::
CCDS55 KYLASAERAALAKALKMTDAQVKTWFQNRRTKWR
230 240 250
250 260 270 280 290
pF1KB7 QKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
291 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:03:40 2016 done: Mon Nov 7 01:03:41 2016
Total Scan time: 3.080 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]