Result of FASTA (omim) for
pFN21AB6908
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6908, 224 aa
1>>>pF1KB6908 224 - 224 aa - 224 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3325+/-0.00034; mu= 14.7952+/- 0.021
mean_var=74.8421+/-14.895, 0's: 0 Z-trim(115.1): 53 B-trim: 319 in 1/53
Lambda= 0.148252
statistics sampled from 25269 (25323) to 25269 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.297), width: 16
Scan time: 6.360
The best scores are: opt bits E(85289)
NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans ( 224) 1469 323.1 2.4e-88
XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-pr ( 229) 1369 301.7 6.7e-82
XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-pr ( 191) 1232 272.3 3.9e-73
XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-pr ( 196) 1132 250.9 1.1e-66
XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-pr ( 142) 305 74.0 1.5e-13
NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 305 74.0 1.5e-13
NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-tr ( 142) 305 74.0 1.5e-13
NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 305 74.0 1.5e-13
NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 291 70.9 9.5e-13
NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 291 70.9 9.5e-13
NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 287 70.5 5.4e-12
NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans ( 108) 277 67.9 7.6e-12
NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl ( 268) 266 65.8 7.9e-11
NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457) 266 66.0 1.2e-10
NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 266 66.0 1.2e-10
NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 266 66.0 1.2e-10
XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 263 65.3 1.7e-10
NP_851939 (OMIM: 607062) peptidyl-prolyl cis-trans ( 222) 250 62.3 7.3e-10
NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-tr ( 221) 239 60.0 3.7e-09
NP_060416 (OMIM: 614505,614557) peptidyl-prolyl ci ( 211) 229 57.8 1.6e-08
XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 214 54.3 6.7e-08
XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 214 54.3 6.7e-08
NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 214 54.3 6.7e-08
XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 214 54.3 6.7e-08
XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 214 54.3 6.7e-08
NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 214 54.3 6.7e-08
XP_011523402 (OMIM: 259450,607063,610968) PREDICTE ( 510) 215 55.1 2.5e-07
NP_068758 (OMIM: 259450,607063,610968) peptidyl-pr ( 582) 215 55.1 2.8e-07
XP_011523401 (OMIM: 259450,607063,610968) PREDICTE ( 601) 215 55.1 2.9e-07
NP_001271272 (OMIM: 616257) peptidyl-prolyl cis-tr ( 338) 205 52.8 8e-07
NP_057678 (OMIM: 610571) peptidyl-prolyl cis-trans ( 201) 199 51.4 1.3e-06
XP_011513417 (OMIM: 616257) PREDICTED: peptidyl-pr ( 359) 187 49.0 1.2e-05
NP_009201 (OMIM: 616257) peptidyl-prolyl cis-trans ( 570) 187 49.1 1.8e-05
NP_001271270 (OMIM: 616257) peptidyl-prolyl cis-tr ( 623) 187 49.2 1.9e-05
XP_005246695 (OMIM: 607062) PREDICTED: peptidyl-pr ( 181) 179 47.1 2.3e-05
NP_001137254 (OMIM: 610571) peptidyl-prolyl cis-tr ( 146) 170 45.1 7.4e-05
XP_016868231 (OMIM: 604839) PREDICTED: inactive pe ( 266) 168 44.8 0.00016
XP_006716216 (OMIM: 604839) PREDICTED: inactive pe ( 282) 168 44.9 0.00017
XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317) 168 44.9 0.00018
NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322) 168 44.9 0.00019
NP_003593 (OMIM: 604839) inactive peptidyl-prolyl ( 327) 168 44.9 0.00019
NP_473374 (OMIM: 600620) peptidyl-prolyl cis-trans ( 80) 145 39.6 0.0019
XP_011531001 (OMIM: 600620) PREDICTED: peptidyl-pr ( 100) 145 39.6 0.0022
NP_001268233 (OMIM: 604839) inactive peptidyl-prol ( 297) 147 40.4 0.0039
>>NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans iso (224 aa)
initn: 1469 init1: 1469 opt: 1469 Z-score: 1707.1 bits: 323.1 E(85289): 2.4e-88
Smith-Waterman score: 1469; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)
10 20 30 40 50 60
pF1KB6 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
130 140 150 160 170 180
190 200 210 220
pF1KB6 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
::::::::::::::::::::::::::::::::::::::::::::
NP_002 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
190 200 210 220
>>XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-prolyl (229 aa)
initn: 1396 init1: 1369 opt: 1369 Z-score: 1591.3 bits: 301.7 E(85289): 6.7e-82
Smith-Waterman score: 1369; 99.5% identity (99.5% similar) in 209 aa overlap (1-209:1-209)
10 20 30 40 50 60
pF1KB6 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
130 140 150 160 170 180
190 200 210 220
pF1KB6 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
::::::::::::::::::::::::::: :
XP_016 TMSKGEKARLEIEPEWAYGKKGQPDAKYPFFPFIIKVEKKKTSRSPLRM
190 200 210 220
>>XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-prolyl (191 aa)
initn: 1232 init1: 1232 opt: 1232 Z-score: 1434.1 bits: 272.3 E(85289): 3.9e-73
Smith-Waterman score: 1232; 100.0% identity (100.0% similar) in 188 aa overlap (37-224:4-191)
10 20 30 40 50 60
pF1KB6 QRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
::::::::::::::::::::::::::::::
XP_011 MLKFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
10 20 30
70 80 90 100 110 120
pF1KB6 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
100 110 120 130 140 150
190 200 210 220
pF1KB6 KARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
::::::::::::::::::::::::::::::::::::::
XP_011 KARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
160 170 180 190
>>XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-prolyl (196 aa)
initn: 1183 init1: 1132 opt: 1132 Z-score: 1318.3 bits: 250.9 E(85289): 1.1e-66
Smith-Waterman score: 1132; 99.4% identity (99.4% similar) in 173 aa overlap (37-209:4-176)
10 20 30 40 50 60
pF1KB6 QRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
::::::::::::::::::::::::::::::
XP_016 MLKFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
10 20 30
70 80 90 100 110 120
pF1KB6 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
100 110 120 130 140 150
190 200 210 220
pF1KB6 KARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
::::::::::::::::::::: :
XP_016 KARLEIEPEWAYGKKGQPDAKYPFFPFIIKVEKKKTSRSPLRM
160 170 180 190
>>XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-prolyl (142 aa)
initn: 264 init1: 128 opt: 305 Z-score: 364.4 bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)
80 90 100 110 120 130
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
:: : .: :. :. . .::::.:
XP_005 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
::: :.::: ::... . .:. :..:.:.::.:::..:: : .::: .: :
XP_005 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
60 70 80 90 100
200 210 220
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID
: .::..: : ::: .: :.:::::. :.
XP_005 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
110 120 130 140
>>NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans iso (142 aa)
initn: 264 init1: 128 opt: 305 Z-score: 364.4 bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)
80 90 100 110 120 130
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
:: : .: :. :. . .::::.:
NP_476 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
::: :.::: ::... . .:. :..:.:.::.:::..:: : .::: .: :
NP_476 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
60 70 80 90 100
200 210 220
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID
: .::..: : ::: .: :.:::::. :.
NP_476 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
110 120 130 140
>>NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-trans (142 aa)
initn: 264 init1: 128 opt: 305 Z-score: 364.4 bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)
80 90 100 110 120 130
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
:: : .: :. :. . .::::.:
NP_001 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
::: :.::: ::... . .:. :..:.:.::.:::..:: : .::: .: :
NP_001 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
60 70 80 90 100
200 210 220
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID
: .::..: : ::: .: :.:::::. :.
NP_001 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
110 120 130 140
>>NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans iso (142 aa)
initn: 264 init1: 128 opt: 305 Z-score: 364.4 bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)
80 90 100 110 120 130
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
:: : .: :. :. . .::::.:
NP_004 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
::: :.::: ::... . .:. :..:.:.::.:::..:: : .::: .: :
NP_004 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
60 70 80 90 100
200 210 220
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID
: .::..: : ::: .: :.:::::. :.
NP_004 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
110 120 130 140
>>NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa)
initn: 298 init1: 164 opt: 291 Z-score: 349.9 bits: 70.9 E(85289): 9.5e-13
Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (116-224:8-108)
90 100 110 120 130 140
pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT
.. :: .:::.:. ::: ::: :.::
NP_463 MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK
10 20 30
150 160 170 180 190 200
pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ
::.. . .: ::..: .: .:::::.:.. :: :..:.: : :..::: :.
NP_463 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH
40 50 60 70 80
210 220
pF1KB6 PDAKIPPNAKLTFEVELVDID
: :::.: :.:.:::. ..
NP_463 PGI-IPPHATLVFDVELLKLE
90 100
>>NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa)
initn: 298 init1: 164 opt: 291 Z-score: 349.9 bits: 70.9 E(85289): 9.5e-13
Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (116-224:8-108)
90 100 110 120 130 140
pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT
.. :: .:::.:. ::: ::: :.::
NP_000 MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK
10 20 30
150 160 170 180 190 200
pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ
::.. . .: ::..: .: .:::::.:.. :: :..:.: : :..::: :.
NP_000 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH
40 50 60 70 80
210 220
pF1KB6 PDAKIPPNAKLTFEVELVDID
: :::.: :.:.:::. ..
NP_000 PGI-IPPHATLVFDVELLKLE
90 100
224 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:03:25 2016 done: Fri Nov 4 13:03:26 2016
Total Scan time: 6.360 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]