Result of FASTA (ccds) for
pFN21AB6908
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6908, 224 aa
1>>>pF1KB6908 224 - 224 aa - 224 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7110+/-0.000791; mu= 12.4092+/- 0.047
mean_var=75.1812+/-14.776, 0's: 0 Z-trim(108.0): 31 B-trim: 0 in 0/52
Lambda= 0.147918
statistics sampled from 9869 (9900) to 9869 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.304), width: 16
Scan time: 1.880
The best scores are: opt bits E(32554)
CCDS9683.1 FKBP3 gene_id:2287|Hs108|chr14 ( 224) 1469 322.4 1.4e-88
CCDS8063.1 FKBP2 gene_id:2286|Hs108|chr11 ( 142) 305 73.9 5.9e-14
CCDS13014.1 FKBP1A gene_id:2280|Hs108|chr20 ( 108) 291 70.9 3.7e-13
CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 ( 459) 287 70.3 2.3e-12
CCDS1706.1 FKBP1B gene_id:2281|Hs108|chr2 ( 108) 277 67.9 2.9e-12
CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 ( 268) 266 65.7 3.2e-11
CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 ( 457) 266 65.8 5e-11
>>CCDS9683.1 FKBP3 gene_id:2287|Hs108|chr14 (224 aa)
initn: 1469 init1: 1469 opt: 1469 Z-score: 1703.5 bits: 322.4 E(32554): 1.4e-88
Smith-Waterman score: 1469; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)
10 20 30 40 50 60
pF1KB6 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
130 140 150 160 170 180
190 200 210 220
pF1KB6 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
::::::::::::::::::::::::::::::::::::::::::::
CCDS96 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
190 200 210 220
>>CCDS8063.1 FKBP2 gene_id:2286|Hs108|chr11 (142 aa)
initn: 264 init1: 128 opt: 305 Z-score: 364.1 bits: 73.9 E(32554): 5.9e-14
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)
80 90 100 110 120 130
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
:: : .: :. :. . .::::.:
CCDS80 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
::: :.::: ::... . .:. :..:.:.::.:::..:: : .::: .: :
CCDS80 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
60 70 80 90 100
200 210 220
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID
: .::..: : ::: .: :.:::::. :.
CCDS80 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
110 120 130 140
>>CCDS13014.1 FKBP1A gene_id:2280|Hs108|chr20 (108 aa)
initn: 298 init1: 164 opt: 291 Z-score: 349.7 bits: 70.9 E(32554): 3.7e-13
Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (116-224:8-108)
90 100 110 120 130 140
pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT
.. :: .:::.:. ::: ::: :.::
CCDS13 MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK
10 20 30
150 160 170 180 190 200
pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ
::.. . .: ::..: .: .:::::.:.. :: :..:.: : :..::: :.
CCDS13 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH
40 50 60 70 80
210 220
pF1KB6 PDAKIPPNAKLTFEVELVDID
: :::.: :.:.:::. ..
CCDS13 PGI-IPPHATLVFDVELLKLE
90 100
>>CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 (459 aa)
initn: 296 init1: 139 opt: 287 Z-score: 335.6 bits: 70.3 E(32554): 2.3e-12
Smith-Waterman score: 287; 45.8% identity (66.9% similar) in 118 aa overlap (109-222:27-136)
80 90 100 110 120 130
pF1KB6 SKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLK----KGDKTNFPKKGDVVHCW
:: ..::: .: :..: :: :
CCDS85 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVH
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
::: : ::: ::.... .: : .:: .: :.::..:: :. ::. :: .. .:
CCDS85 YTGWLLDGTKFDSSLD---RKDK----FSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP
60 70 80 90 100
200 210 220
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID
:.:::. :.: :::::: :.::::: .
CCDS85 EYAYGSAGSPP-KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGA
110 120 130 140 150 160
>>CCDS1706.1 FKBP1B gene_id:2281|Hs108|chr2 (108 aa)
initn: 297 init1: 139 opt: 277 Z-score: 333.6 bits: 67.9 E(32554): 2.9e-12
Smith-Waterman score: 278; 43.2% identity (69.4% similar) in 111 aa overlap (116-224:8-108)
90 100 110 120 130 140
pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT
.. :: .:::::. ::: ::: ::.:
CCDS17 MGVEIETISPGDGRTFPKKGQTCVVH--YTGMLQNGK
10 20 30
150 160 170 180 190 200
pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ
::.. . .: ::..:..: .::.:..:. :: :..:.: :. ::: :.
CCDS17 KFDSS------RDRN-KPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGH
40 50 60 70 80
210 220
pF1KB6 PDAKIPPNAKLTFEVELVDID
: . ::::: : :.:::....
CCDS17 PGV-IPPNATLIFDVELLNLE
90 100
>>CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 (268 aa)
initn: 210 init1: 106 opt: 266 Z-score: 314.9 bits: 65.7 E(32554): 3.2e-11
Smith-Waterman score: 266; 38.3% identity (62.4% similar) in 141 aa overlap (86-222:5-136)
60 70 80 90 100 110
pF1KB6 KDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPK---YT
...: ::..: : .:. : :
CCDS54 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVL
10 20 30
120 130 140 150 160 170
pF1KB6 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI
: : . :. . : :: :. : : :..: ::.. . .: .:. :..: :.::
CCDS54 KIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS------HDRN-EPFVFSLGKGQVI
40 50 60 70 80
180 190 200 210 220
pF1KB6 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQ-PDAKIPPNAKLTFEVELVDID
..:: .. ::.::: .: .::.:::. :. : ::: :: : ::.::.:
CCDS54 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP--KIPSNATLFFEIELLDFKGEDLFED
90 100 110 120 130 140
CCDS54 GGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKA
150 160 170 180 190 200
>>CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 (457 aa)
initn: 184 init1: 106 opt: 266 Z-score: 311.4 bits: 65.8 E(32554): 5e-11
Smith-Waterman score: 266; 38.3% identity (62.4% similar) in 141 aa overlap (86-222:5-136)
60 70 80 90 100 110
pF1KB6 KDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPK---YT
...: ::..: : .:. : :
CCDS48 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVL
10 20 30
120 130 140 150 160 170
pF1KB6 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI
: : . :. . : :: :. : : :..: ::.. . .: .:. :..: :.::
CCDS48 KIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS------HDRN-EPFVFSLGKGQVI
40 50 60 70 80
180 190 200 210 220
pF1KB6 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQ-PDAKIPPNAKLTFEVELVDID
..:: .. ::.::: .: .::.:::. :. : ::: :: : ::.::.:
CCDS48 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP--KIPSNATLFFEIELLDFKGEDLFED
90 100 110 120 130 140
CCDS48 GGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKA
150 160 170 180 190 200
224 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:03:25 2016 done: Fri Nov 4 13:03:25 2016
Total Scan time: 1.880 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]