Result of FASTA (ccds) for
pFN21AB4810
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4810, 305 aa
1>>>pF1KB4810 305 - 305 aa - 305 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6832+/-0.00094; mu= 12.7038+/- 0.056
mean_var=56.6088+/-11.555, 0's: 0 Z-trim(102.6): 19 B-trim: 0 in 0/52
Lambda= 0.170464
statistics sampled from 7012 (7020) to 7012 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.571), E-opt: 0.2 (0.216), width: 16
Scan time: 2.340
The best scores are: opt bits E(32554)
CCDS2886.1 DNASE1L3 gene_id:1776|Hs108|chr3 ( 305) 2001 500.5 6.4e-142
CCDS58836.1 DNASE1L3 gene_id:1776|Hs108|chr3 ( 275) 1324 334.0 7.6e-92
CCDS10507.1 DNASE1 gene_id:1773|Hs108|chr16 ( 282) 795 203.9 1.1e-52
CCDS14747.1 DNASE1L1 gene_id:1774|Hs108|chrX ( 302) 782 200.7 1.1e-51
CCDS42105.1 DNASE1L2 gene_id:1775|Hs108|chr16 ( 299) 466 123.0 2.7e-28
>>CCDS2886.1 DNASE1L3 gene_id:1776|Hs108|chr3 (305 aa)
initn: 2001 init1: 2001 opt: 2001 Z-score: 2661.4 bits: 500.5 E(32554): 6.4e-142
Smith-Waterman score: 2001; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305)
10 20 30 40 50 60
pF1KB4 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
250 260 270 280 290 300
pF1KB4 KSKRS
:::::
CCDS28 KSKRS
>>CCDS58836.1 DNASE1L3 gene_id:1776|Hs108|chr3 (275 aa)
initn: 1324 init1: 1324 opt: 1324 Z-score: 1762.4 bits: 334.0 E(32554): 7.6e-92
Smith-Waterman score: 1738; 90.2% identity (90.2% similar) in 305 aa overlap (1-305:1-275)
10 20 30 40 50 60
pF1KB4 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
::::::::::::::::: :::::::::::::
CCDS58 KDSNNRICPILMEKLNR------------------------------EKLVSVKRSYHYH
70 80 90
130 140 150 160 170 180
pF1KB4 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
220 230 240 250 260 270
pF1KB4 KSKRS
:::::
CCDS58 KSKRS
>>CCDS10507.1 DNASE1 gene_id:1773|Hs108|chr16 (282 aa)
initn: 678 init1: 364 opt: 795 Z-score: 1059.1 bits: 203.9 E(32554): 1.1e-52
Smith-Waterman score: 795; 44.8% identity (72.4% similar) in 279 aa overlap (5-282:7-282)
10 20 30 40 50
pF1KB4 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVM
:. :: : ...:....: .::...:::.:. . . .. ::....: :: ::.
CCDS10 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 EIKDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYH
:..::. :...::... ::.::.: ::::.:::.: :.:. ::. ::.
CCDS10 EVRDSHLTAVGKLLDNLNQDAPD--TYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYY
70 80 90 100 110
120 130 140 150 160 170
pF1KB4 YHDY-QDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKH
: : . :.:.::: .: : : : :..:.:.:::..: .: ::: : .:: ::..
CCDS10 YDDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 RWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIV
.: :. ..::::::::::: . :..::: :.: : ::: :. :::. :.:::::::
CCDS10 KWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATP-THCAYDRIV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 LRGQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLR
. :. . ..::: : :.:: :: :... : .:::.::: :.
CCDS10 VAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
240 250 260 270 280
300
pF1KB4 KKTKSKRS
>>CCDS14747.1 DNASE1L1 gene_id:1774|Hs108|chrX (302 aa)
initn: 701 init1: 406 opt: 782 Z-score: 1041.3 bits: 200.7 E(32554): 1.1e-51
Smith-Waterman score: 782; 41.0% identity (76.4% similar) in 288 aa overlap (9-296:7-287)
10 20 30 40 50 60
pF1KB4 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
::.:. ..: :.:::.::.. . .: ...::..:... ::::....:.
CCDS14 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEV
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
::.. :.:...::: . : :. . : .:::.:: : :...:. . ..: :: :.
CCDS14 VDSSGSAIPLLLRELNRFDGSG-PYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
: . :::.:::::. :. : ... ..:..::::::.. ::.. : .:. .:...:.
CCDS14 D----EDDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
... :..::::: :. . :: ...:::.: : :.:.: :::::. ::.:.:::.::.:
CCDS14 SKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
.. : . .. ..::: ...:::::::..:::.::: .:. :.: . . :.:.
CCDS14 ERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLL
240 250 260 270 280 290
pF1KB4 KSKRS
CCDS14 SLLSPQLCPAA
300
>>CCDS42105.1 DNASE1L2 gene_id:1775|Hs108|chr16 (299 aa)
initn: 643 init1: 280 opt: 466 Z-score: 621.4 bits: 123.0 E(32554): 2.7e-28
Smith-Waterman score: 729; 42.3% identity (65.3% similar) in 300 aa overlap (8-285:7-299)
10 20 30 40 50
pF1KB4 MSRELAPLLLLLLSIHSA--LAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVM
:: : ....: :.:: .::..:::.:: : ..:.:.. :. ::.
CCDS42 MGGPRALLAALWALEAAGTAALRIGAFNIQSFGDSKVSDPACGSIIAKILAGYDLALVQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 EIKDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYH
:..: . :::..: :.. :..: :. :::. :::.: :.:.. ::: .:
CCDS42 EVRDPDLSAVSALMEQINSVSEH--EYSFVSSQPLGRDQYKEMYLFVYRKDAVSVVDTYL
60 70 80 90 100 110
120 130 140 150
pF1KB4 YHDYQDGDADVFSREPFVVWFQSPHT--------------------AVKDFVIIPLHTTP
: : .: ::::::::: :..: : :....:.::::..:
CCDS42 YPDPED----VFSREPFVVKFSAPGTGERAPPLPSRRALTPPPLPAAAQNLVLIPLHAAP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB4 ETSVKEIDELVEVYTDVKHRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIG
. .: ::: : .:: :: .: .....:.::::: :::: . : ::::.. : :::
CCDS42 HQAVAEIDALYDVYLDVIDKWGTDDMLFLGDFNADCSYVRAQDWAAIRLRSSEVFKWLIP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB4 DQEDTTVKKSTNCAYDRIVLRGQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVE
:. :::: .: .::::::: : .. :. :.: .: :::. . : . .:: .:::::::
CCDS42 DSADTTVGNS-DCAYDRIVACGARLRRSLKPQSATVHDFQEEFGLDQTQALAISDHFPVE
240 250 260 270 280 290
280 290 300
pF1KB4 FKLQSSRAFTNSKKSVTLRKKTKSKRS
:. :
CCDS42 VTLKFHR
305 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:14:51 2016 done: Mon Nov 7 01:14:51 2016
Total Scan time: 2.340 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]