Result of FASTA (ccds) for
pFN21AE5116
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5116, 147 aa
1>>>pF1KE5116 147 - 147 aa - 147 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6208+/-0.000776; mu= 9.1705+/- 0.046
mean_var=56.6577+/-11.109, 0's: 0 Z-trim(107.4): 16 B-trim: 0 in 0/51
Lambda= 0.170390
statistics sampled from 9538 (9551) to 9538 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.293), width: 16
Scan time: 1.550
The best scores are: opt bits E(32554)
CCDS7756.1 HBE1 gene_id:3046|Hs108|chr11 ( 147) 968 245.8 7.1e-66
CCDS7755.1 HBG2 gene_id:3048|Hs108|chr11 ( 147) 810 207.0 3.5e-54
CCDS7754.1 HBG1 gene_id:3047|Hs108|chr11 ( 147) 809 206.7 4.2e-54
CCDS7753.1 HBB gene_id:3043|Hs108|chr11 ( 147) 774 198.1 1.6e-51
CCDS31376.1 HBD gene_id:3045|Hs108|chr11 ( 147) 754 193.2 4.9e-50
CCDS10397.1 HBZ gene_id:3050|Hs108|chr16 ( 142) 357 95.6 1.1e-20
CCDS32347.1 HBM gene_id:3042|Hs108|chr16 ( 141) 332 89.5 7.9e-19
CCDS10399.1 HBA1 gene_id:3039|Hs108|chr16 ( 142) 332 89.5 8e-19
CCDS10398.1 HBA2 gene_id:3040|Hs108|chr16 ( 142) 332 89.5 8e-19
CCDS10400.1 HBQ1 gene_id:3049|Hs108|chr16 ( 142) 318 86.0 8.7e-18
CCDS11746.1 CYGB gene_id:114757|Hs108|chr17 ( 190) 259 71.5 2.7e-13
>>CCDS7756.1 HBE1 gene_id:3046|Hs108|chr11 (147 aa)
initn: 968 init1: 968 opt: 968 Z-score: 1296.1 bits: 245.8 E(32554): 7.1e-66
Smith-Waterman score: 968; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::::::::::::::::::::::::
CCDS77 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>CCDS7755.1 HBG2 gene_id:3048|Hs108|chr11 (147 aa)
initn: 810 init1: 810 opt: 810 Z-score: 1086.2 bits: 207.0 E(32554): 3.5e-54
Smith-Waterman score: 810; 79.6% identity (94.6% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
: ::: :.::..::::.:.:::.::::.::::::::::::::::::::::: :::.::::
CCDS77 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
:::::::::::.:::::..:.:: .::.::::::::::::::::::::::.: .:: :::
CCDS77 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::::::.:::.:..:: ::. .::
CCDS77 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>CCDS7754.1 HBG1 gene_id:3047|Hs108|chr11 (147 aa)
initn: 809 init1: 809 opt: 809 Z-score: 1084.9 bits: 206.7 E(32554): 4.2e-54
Smith-Waterman score: 809; 79.6% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
: ::: :.::..::::.:.:::.::::.::::::::::::::::::::::: :::.::::
CCDS77 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
:::::::::::.::: :..:.:: .::.::::::::::::::::::::::.: .:: :::
CCDS77 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::::::.:::.:.::: ::. .::
CCDS77 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>CCDS7753.1 HBB gene_id:3043|Hs108|chr11 (147 aa)
initn: 774 init1: 774 opt: 774 Z-score: 1038.4 bits: 198.1 E(32554): 1.6e-51
Smith-Waterman score: 774; 75.5% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
:::.: :::.:::.::.:.::.:.:::::::::::::::::::.:::.::.:.:..::::
CCDS77 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
::::::::: .:.:.. ..:::: .:: ::::::::::::::::.:::::.: .:: :::
CCDS77 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
::::: ::::.::.:..:: :::::::
CCDS77 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>CCDS31376.1 HBD gene_id:3045|Hs108|chr11 (147 aa)
initn: 754 init1: 754 opt: 754 Z-score: 1011.8 bits: 193.2 E(32554): 4.9e-50
Smith-Waterman score: 754; 72.8% identity (94.6% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
:::.: :::.::..::.:.::. .:::::::::::::::::::.:::.::::.:..::::
CCDS31 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
::::::::: .:.:.. ..:::: .:..::::::::::::::::.:::::.: .:: .::
CCDS31 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::..:::.::.:..:: :::::::
CCDS31 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>CCDS10397.1 HBZ gene_id:3050|Hs108|chr16 (142 aa)
initn: 287 init1: 287 opt: 357 Z-score: 484.7 bits: 95.6 E(32554): 1.1e-20
Smith-Waterman score: 357; 40.0% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEE--AGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
.: :.. ..:.:.:.... : :.: ::.. .: :. .: : .: : :.
CCDS10 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
...:::.::... :::.:..:.. :..:::::: :.::: :::::.. ... ::..
CCDS10 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
: .:: :..:::.:..:.:. .:..::
CCDS10 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>CCDS32347.1 HBM gene_id:3042|Hs108|chr16 (141 aa)
initn: 293 init1: 259 opt: 332 Z-score: 451.5 bits: 89.5 E(32554): 7.9e-19
Smith-Waterman score: 332; 36.6% identity (74.5% similar) in 145 aa overlap (4-146:2-140)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEA--GGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
..:.:.: ....:. . .:: :.: : ::..::: :. .: .. .. . .:
CCDS32 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLL--
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
.::...:.. : :....:::. :.. :..:: :.::: :: :: . . ..::.:
CCDS32 ----SHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
. ::: ..::::.:....::..:..::
CCDS32 LQDEFTVQMQAAWDKFLTGVAVVLTEKYR
120 130 140
>>CCDS10399.1 HBA1 gene_id:3039|Hs108|chr16 (142 aa)
initn: 264 init1: 264 opt: 332 Z-score: 451.4 bits: 89.5 E(32554): 8e-19
Smith-Waterman score: 332; 37.9% identity (72.4% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVE--EAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
.. .:. : . :.:.... : :.::: :... .: :. .: : .:: :.
CCDS10 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
.::.::::: .. .:. ..:.. :.. ::.:: ::.::: :::::.. ... ::.:
CCDS10 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
. :::: :.:. .:....:. .:. ::
CCDS10 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>CCDS10398.1 HBA2 gene_id:3040|Hs108|chr16 (142 aa)
initn: 264 init1: 264 opt: 332 Z-score: 451.4 bits: 89.5 E(32554): 8e-19
Smith-Waterman score: 332; 37.9% identity (72.4% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVE--EAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
.. .:. : . :.:.... : :.::: :... .: :. .: : .:: :.
CCDS10 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
.::.::::: .. .:. ..:.. :.. ::.:: ::.::: :::::.. ... ::.:
CCDS10 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
. :::: :.:. .:....:. .:. ::
CCDS10 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>CCDS10400.1 HBQ1 gene_id:3049|Hs108|chr16 (142 aa)
initn: 306 init1: 228 opt: 318 Z-score: 432.8 bits: 86.0 E(32554): 8.7e-18
Smith-Waterman score: 318; 38.6% identity (70.3% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKM--NVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
..::..: : .::.:. :: ::: : ....: :. .: : .:: : :.
CCDS10 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYF-SHLDLS-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
.:.:::.:: ... :.. .:.: :.. ::.:: .:.::: .:.:::. ... :: :
CCDS10 SQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
. .:.: .::. .:..: : ::. .:
CCDS10 YPGDFSPALQASLDKFLSHVISALVSEYR
120 130 140
147 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 21:29:42 2016 done: Mon Nov 7 21:29:42 2016
Total Scan time: 1.550 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]