Result of FASTA (omim) for
pFN21AE6221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6221, 301 aa
1>>>pF1KE6221 301 - 301 aa - 301 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5541+/-0.000276; mu= 11.6650+/- 0.017
mean_var=115.5966+/-23.273, 0's: 0 Z-trim(122.1): 6 B-trim: 33 in 1/52
Lambda= 0.119289
statistics sampled from 39648 (39655) to 39648 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.465), width: 16
Scan time: 6.830
The best scores are: opt bits E(85289)
NP_004580 (OMIM: 220110,603644) protein SCO1 homol ( 301) 2077 367.4 1.9e-101
XP_005256808 (OMIM: 220110,603644) PREDICTED: prot ( 190) 1279 229.9 3e-60
NP_001162581 (OMIM: 604272,604377,608908) protein ( 266) 712 132.5 9.1e-31
NP_005129 (OMIM: 604272,604377,608908) protein SCO ( 266) 712 132.5 9.1e-31
NP_001162580 (OMIM: 604272,604377,608908) protein ( 266) 712 132.5 9.1e-31
NP_001162582 (OMIM: 604272,604377,608908) protein ( 266) 712 132.5 9.1e-31
>>NP_004580 (OMIM: 220110,603644) protein SCO1 homolog, (301 aa)
initn: 2077 init1: 2077 opt: 2077 Z-score: 1942.1 bits: 367.4 E(85289): 1.9e-101
Smith-Waterman score: 2077; 100.0% identity (100.0% similar) in 301 aa overlap (1-301:1-301)
10 20 30 40 50 60
pF1KE6 MAMLVLVPGRVMRPLGGQLWRFLPRGLEFWGPAEGTARVLLRQFCARQAEAWRASGRPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAMLVLVPGRVMRPLGGQLWRFLPRGLEFWGPAEGTARVLLRQFCARQAEAWRASGRPGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 CLGTRPLSTARPPPPWSQKGPGDSTRPSKPGPVSWKSLAITFAIGGALLAGMKHVKKEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CLGTRPLSTARPPPPWSQKGPGDSTRPSKPGPVSWKSLAITFAIGGALLAGMKHVKKEKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EKLEKERQRHIGKPLLGGPFSLTTHTGERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKLEKERQRHIGKPLLGGPFSLTTHTGERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFSPKLVGLTGTREEVDQVARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFSPKLVGLTGTREEVDQVARA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKRKGEIAASIATHMRPYRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKRKGEIAASIATHMRPYRKK
250 260 270 280 290 300
pF1KE6 S
:
NP_004 S
>>XP_005256808 (OMIM: 220110,603644) PREDICTED: protein (190 aa)
initn: 1279 init1: 1279 opt: 1279 Z-score: 1202.7 bits: 229.9 E(85289): 3e-60
Smith-Waterman score: 1279; 100.0% identity (100.0% similar) in 190 aa overlap (112-301:1-190)
90 100 110 120 130 140
pF1KE6 GDSTRPSKPGPVSWKSLAITFAIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLGGPFS
::::::::::::::::::::::::::::::
XP_005 MKHVKKEKAEKLEKERQRHIGKPLLGGPFS
10 20 30
150 160 170 180 190 200
pF1KE6 LTTHTGERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTTHTGERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE6 SIDPERDTKEAIANYVKEFSPKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIDPERDTKEAIANYVKEFSPKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHT
100 110 120 130 140 150
270 280 290 300
pF1KE6 IIMYLIGPDGEFLDYFGQNKRKGEIAASIATHMRPYRKKS
::::::::::::::::::::::::::::::::::::::::
XP_005 IIMYLIGPDGEFLDYFGQNKRKGEIAASIATHMRPYRKKS
160 170 180 190
>>NP_001162581 (OMIM: 604272,604377,608908) protein SCO2 (266 aa)
initn: 667 init1: 617 opt: 712 Z-score: 673.3 bits: 132.5 E(85289): 9.1e-31
Smith-Waterman score: 712; 44.1% identity (72.7% similar) in 227 aa overlap (76-298:36-262)
50 60 70 80 90 100
pF1KE6 ARQAEAWRASGRPGYCLGTRPLSTARPPPPW--SQKGPGDSTRPSKP-GPVSWKSLAITF
: :..::... ..: :: : ::
NP_001 RSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITG
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE6 AIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLG-GPFSLTTHTGERKTDKDYLGQWLL
.:..: .. .. :: . ...: . . . .: : : : : :. . :. :::.:
NP_001 LFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVL
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE6 IYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFS
.:::::::::.::.::::..::: .... :: . :.::..::::: ::.: ::..:
NP_001 MYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFH
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE6 PKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNK
:.:.::::. ..: :....:::::. ::::::.::::::.: .::..::: : ::.:...
NP_001 PRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSR
190 200 210 220 230 240
290 300
pF1KE6 RKGEIAASIATHMRPYRKKS
.:. :. :: .:
NP_001 SAEQISDSVRRHMAAFRSVLS
250 260
>>NP_005129 (OMIM: 604272,604377,608908) protein SCO2 ho (266 aa)
initn: 667 init1: 617 opt: 712 Z-score: 673.3 bits: 132.5 E(85289): 9.1e-31
Smith-Waterman score: 712; 44.1% identity (72.7% similar) in 227 aa overlap (76-298:36-262)
50 60 70 80 90 100
pF1KE6 ARQAEAWRASGRPGYCLGTRPLSTARPPPPW--SQKGPGDSTRPSKP-GPVSWKSLAITF
: :..::... ..: :: : ::
NP_005 RSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITG
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE6 AIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLG-GPFSLTTHTGERKTDKDYLGQWLL
.:..: .. .. :: . ...: . . . .: : : : : :. . :. :::.:
NP_005 LFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVL
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE6 IYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFS
.:::::::::.::.::::..::: .... :: . :.::..::::: ::.: ::..:
NP_005 MYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFH
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE6 PKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNK
:.:.::::. ..: :....:::::. ::::::.::::::.: .::..::: : ::.:...
NP_005 PRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSR
190 200 210 220 230 240
290 300
pF1KE6 RKGEIAASIATHMRPYRKKS
.:. :. :: .:
NP_005 SAEQISDSVRRHMAAFRSVLS
250 260
>>NP_001162580 (OMIM: 604272,604377,608908) protein SCO2 (266 aa)
initn: 667 init1: 617 opt: 712 Z-score: 673.3 bits: 132.5 E(85289): 9.1e-31
Smith-Waterman score: 712; 44.1% identity (72.7% similar) in 227 aa overlap (76-298:36-262)
50 60 70 80 90 100
pF1KE6 ARQAEAWRASGRPGYCLGTRPLSTARPPPPW--SQKGPGDSTRPSKP-GPVSWKSLAITF
: :..::... ..: :: : ::
NP_001 RSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITG
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE6 AIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLG-GPFSLTTHTGERKTDKDYLGQWLL
.:..: .. .. :: . ...: . . . .: : : : : :. . :. :::.:
NP_001 LFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVL
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE6 IYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFS
.:::::::::.::.::::..::: .... :: . :.::..::::: ::.: ::..:
NP_001 MYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFH
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE6 PKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNK
:.:.::::. ..: :....:::::. ::::::.::::::.: .::..::: : ::.:...
NP_001 PRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSR
190 200 210 220 230 240
290 300
pF1KE6 RKGEIAASIATHMRPYRKKS
.:. :. :: .:
NP_001 SAEQISDSVRRHMAAFRSVLS
250 260
>>NP_001162582 (OMIM: 604272,604377,608908) protein SCO2 (266 aa)
initn: 667 init1: 617 opt: 712 Z-score: 673.3 bits: 132.5 E(85289): 9.1e-31
Smith-Waterman score: 712; 44.1% identity (72.7% similar) in 227 aa overlap (76-298:36-262)
50 60 70 80 90 100
pF1KE6 ARQAEAWRASGRPGYCLGTRPLSTARPPPPW--SQKGPGDSTRPSKP-GPVSWKSLAITF
: :..::... ..: :: : ::
NP_001 RSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITG
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE6 AIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLG-GPFSLTTHTGERKTDKDYLGQWLL
.:..: .. .. :: . ...: . . . .: : : : : :. . :. :::.:
NP_001 LFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVL
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE6 IYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFS
.:::::::::.::.::::..::: .... :: . :.::..::::: ::.: ::..:
NP_001 MYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFH
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE6 PKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNK
:.:.::::. ..: :....:::::. ::::::.::::::.: .::..::: : ::.:...
NP_001 PRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSR
190 200 210 220 230 240
290 300
pF1KE6 RKGEIAASIATHMRPYRKKS
.:. :. :: .:
NP_001 SAEQISDSVRRHMAAFRSVLS
250 260
301 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:12:47 2016 done: Tue Nov 8 11:12:48 2016
Total Scan time: 6.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]