Result of FASTA (ccds) for
pFN21AE4526
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4526, 574 aa
1>>>pF1KE4526 574 - 574 aa - 574 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7556+/-0.00101; mu= -3.8435+/- 0.061
mean_var=348.0146+/-72.243, 0's: 0 Z-trim(115.3): 21 B-trim: 393 in 1/54
Lambda= 0.068750
statistics sampled from 15799 (15816) to 15799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.486), width: 16
Scan time: 3.640
The best scores are: opt bits E(32554)
CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15 ( 574) 4089 419.4 6.1e-117
CCDS4129.1 LOX gene_id:4015|Hs108|chr5 ( 417) 1211 133.8 4.1e-31
CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2 ( 608) 758 89.0 1.8e-17
CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2 ( 753) 758 89.1 2.1e-17
CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10 ( 756) 739 87.2 7.9e-17
CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8 ( 774) 738 87.1 8.6e-17
>>CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15 (574 aa)
initn: 4089 init1: 4089 opt: 4089 Z-score: 2213.0 bits: 419.4 E(32554): 6.1e-117
Smith-Waterman score: 4089; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574)
10 20 30 40 50 60
pF1KE4 MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK
490 500 510 520 530 540
550 560 570
pF1KE4 YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
::::::::::::::::::::::::::::::::::
CCDS10 YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
550 560 570
>>CCDS4129.1 LOX gene_id:4015|Hs108|chr5 (417 aa)
initn: 1343 init1: 1168 opt: 1211 Z-score: 672.1 bits: 133.8 E(32554): 4.1e-31
Smith-Waterman score: 1211; 64.4% identity (80.7% similar) in 270 aa overlap (308-571:149-414)
280 290 300 310 320 330
pF1KE4 LYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYAN--PPPEAYGPPRALEPPYLPVR
: : .: :: .. : . . :: : .
CCDS41 PTARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDG--MVGDDPYNPYK
120 130 140 150 160 170
340 350 360 370 380 390
pF1KE4 SSDTPPPGGERNGAQQGRLSVGSVYRPNQNG----RGLPDLVPDPNYVQASTYVQRAHLY
:: : . . .. : :. :::. . :::::: :: :.:::::::. .:
CCDS41 YSDDNPYYNYYDTYERPR--PGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMY
180 190 200 210 220 230
400 410 420 430 440 450
pF1KE4 SLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQH
.:::::::.::::::: .. ::: :::::::::::::::.::::.:::..:::::::::
CCDS41 NLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQH
240 250 260 270 280 290
460 470 480 490 500 510
pF1KE4 YHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDT
::::::::::::::: : ..:::::::::::::..::.: .:.:::.::::::::::::
CCDS41 YHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDT
300 310 320 330 340 350
520 530 540 550 560 570
pF1KE4 YNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKI
:.:::::::::::::.:::::::: :::.:.: :::.:::::::.:.:::... :..: :
CCDS41 YGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTI
360 370 380 390 400 410
pF1KE4 VQS
CCDS41 SPY
>>CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2 (608 aa)
initn: 777 init1: 507 opt: 758 Z-score: 427.1 bits: 89.0 E(32554): 1.8e-17
Smith-Waterman score: 758; 54.0% identity (73.8% similar) in 202 aa overlap (371-571:385-584)
350 360 370 380 390 400
pF1KE4 PPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEK
::. :: ..:.. :. : :::::.
CCDS74 DQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEEN
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE4 CLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSH
::::.: . . : : :::: ....: : ::: :. ::.: :: :: :::::: :.:
CCDS74 CLASSARSANWP-YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTH
420 430 440 450 460 470
470 480 490 500 510
pF1KE4 YDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQ
::.: . .: ::::::::::::::. :. ::: :.. ::.. ::.: : :::::
CCDS74 YDIL-TPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE4 WIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
:::::::.::::::.: .::.. : :::::::...:: .: :. . . ::.:
CCDS74 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
540 550 560 570 580 590
CCDS74 NRRFERYPGQTSNQII
600
>>CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2 (753 aa)
initn: 748 init1: 507 opt: 758 Z-score: 425.8 bits: 89.1 E(32554): 2.1e-17
Smith-Waterman score: 758; 54.0% identity (73.8% similar) in 202 aa overlap (371-571:530-729)
350 360 370 380 390 400
pF1KE4 PPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEK
::. :: ..:.. :. : :::::.
CCDS19 DQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEEN
500 510 520 530 540 550
410 420 430 440 450 460
pF1KE4 CLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSH
::::.: . . : : :::: ....: : ::: :. ::.: :: :: :::::: :.:
CCDS19 CLASSARSANWP-YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTH
560 570 580 590 600 610
470 480 490 500 510
pF1KE4 YDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQ
::.: . .: ::::::::::::::. :. ::: :.. ::.. ::.: : :::::
CCDS19 YDIL-TPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
620 630 640 650 660 670
520 530 540 550 560 570
pF1KE4 WIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
:::::::.::::::.: .::.. : :::::::...:: .: :. . . ::.:
CCDS19 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
680 690 700 710 720 730
CCDS19 NRRFERYPGQTSNQII
740 750
>>CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10 (756 aa)
initn: 598 init1: 478 opt: 739 Z-score: 415.6 bits: 87.2 E(32554): 7.9e-17
Smith-Waterman score: 739; 46.6% identity (66.5% similar) in 251 aa overlap (322-569:483-731)
300 310 320 330 340
pF1KE4 DPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPP--GGERNGA
: ::: : . :: : : .:.:
CCDS74 NWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGP
460 470 480 490 500 510
350 360 370 380 390 400
pF1KE4 QQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAP
. . : . . :::: . . :: ..:.. : .: :: ::.::...:
CCDS74 VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHM
520 530 540 550 560 570
410 420 430 440 450 460
pF1KE4 EATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATG
. : : :::: .. : : .:: :. : .: ::.::.::::.. :.::::: . .:
CCDS74 DWP-YGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLL-TLNG
580 590 600 610 620 630
470 480 490 500 510 520
pF1KE4 KKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQP
.::::::::::::::..: : .::::.. ::.. ::.::: ::::::.::::: :
CCDS74 SKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGP
640 650 660 670 680 690
530 540 550 560 570
pF1KE4 GNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
::::..: :::.: : ::::.::...: .: :. : ::
CCDS74 GNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQR
700 710 720 730 740 750
CCDS74 LRNNLI
>>CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8 (774 aa)
initn: 706 init1: 471 opt: 738 Z-score: 414.9 bits: 87.1 E(32554): 8.6e-17
Smith-Waterman score: 738; 46.5% identity (72.2% similar) in 230 aa overlap (344-571:525-748)
320 330 340 350 360 370
pF1KE4 ANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLV
:: . :: .. :. .... ::::
CCDS34 WHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETA---PDLV
500 510 520 530 540 550
380 390 400 410 420 430
pF1KE4 PDPNYVQASTYVQRAHLYSLRCAAEEKCL-ASTAYAPEATDYDVRVLLRFPQRVKNQGTA
. ..:: .::.. .. :.:: ::.:: ::.: . .: : : :::: ....:.: .
CCDS34 LNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGY--RRLLRFSSQIHNNGQS
560 570 580 590 600
440 450 460 470 480 490
pF1KE4 DFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNL
:: :. ::.: ::.::.:::::. :.:::::. .: ::::::::::::::. :.
CCDS34 DFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNL-NGTKVAEGHKASFCLEDTECEGDIQ
610 620 630 640 650 660
500 510 520 530 540 550
pF1KE4 KRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNN
: : :.. ::.. ::.: : ::::::.::::: ::.:...: .::.. : :::..::
CCDS34 KNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNN
670 680 690 700 710 720
560 570
pF1KE4 VVRCNIHYTGRYVSATNCKIVQS
...: .: :. . ::.:
CCDS34 IMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ
730 740 750 760 770
574 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:10:48 2016 done: Sun Nov 6 09:10:49 2016
Total Scan time: 3.640 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]