Result of FASTA (omim) for
pFN21AE1568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1568, 309 aa
1>>>pF1KE1568 309 - 309 aa - 309 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9237+/-0.000359; mu= 12.8801+/- 0.022
mean_var=77.6636+/-15.815, 0's: 0 Z-trim(113.9): 144 B-trim: 185 in 1/50
Lambda= 0.145534
statistics sampled from 23265 (23412) to 23265 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.275), width: 16
Scan time: 6.350
The best scores are: opt bits E(85289)
NP_006800 (OMIM: 616049) mitochondrial import rece ( 309) 2007 430.8 1.7e-120
XP_011526803 (OMIM: 616049) PREDICTED: mitochondri ( 283) 1749 376.6 3.2e-104
XP_005260311 (OMIM: 616049) PREDICTED: mitochondri ( 207) 1330 288.6 7.4e-78
XP_016883089 (OMIM: 616049) PREDICTED: mitochondri ( 190) 1206 262.5 4.7e-70
XP_016869244 (OMIM: 603395,615505) PREDICTED: sper ( 814) 895 197.5 7.5e-50
XP_011515545 (OMIM: 603395,615505) PREDICTED: sper ( 926) 895 197.5 8.4e-50
XP_011515544 (OMIM: 603395,615505) PREDICTED: sper ( 926) 895 197.5 8.4e-50
NP_757367 (OMIM: 603395,615505) sperm-associated a ( 926) 895 197.5 8.4e-50
NP_003105 (OMIM: 603395,615505) sperm-associated a ( 926) 895 197.5 8.4e-50
XP_016869243 (OMIM: 603395,615505) PREDICTED: sper ( 961) 895 197.5 8.6e-50
XP_011515543 (OMIM: 603395,615505) PREDICTED: sper ( 871) 847 187.4 8.6e-47
XP_011515542 (OMIM: 603395,615505) PREDICTED: sper ( 875) 474 109.1 3.2e-23
NP_078880 (OMIM: 611477) RNA polymerase II-associa ( 665) 289 70.2 1.3e-11
NP_001139547 (OMIM: 611477) RNA polymerase II-asso ( 631) 284 69.2 2.5e-11
NP_001139548 (OMIM: 611477) RNA polymerase II-asso ( 506) 270 66.2 1.6e-10
NP_003305 (OMIM: 601963) tetratricopeptide repeat ( 292) 266 65.2 1.8e-10
NP_001269429 (OMIM: 601963) tetratricopeptide repe ( 292) 266 65.2 1.8e-10
XP_011515547 (OMIM: 603395,615505) PREDICTED: sper ( 487) 255 63.0 1.4e-09
NP_060338 (OMIM: 610732) tetratricopeptide repeat ( 705) 242 60.4 1.2e-08
XP_016873439 (OMIM: 610732) PREDICTED: tetratricop ( 753) 242 60.4 1.3e-08
XP_016873438 (OMIM: 610732) PREDICTED: tetratricop ( 755) 242 60.4 1.3e-08
XP_016873437 (OMIM: 610732) PREDICTED: tetratricop ( 760) 242 60.4 1.3e-08
XP_016873436 (OMIM: 610732) PREDICTED: tetratricop ( 774) 242 60.4 1.3e-08
XP_005271661 (OMIM: 610732) PREDICTED: tetratricop ( 777) 242 60.4 1.3e-08
XP_016873435 (OMIM: 610732) PREDICTED: tetratricop ( 777) 242 60.4 1.3e-08
XP_016873432 (OMIM: 610732) PREDICTED: tetratricop ( 777) 242 60.4 1.3e-08
XP_016873434 (OMIM: 610732) PREDICTED: tetratricop ( 777) 242 60.4 1.3e-08
XP_016873433 (OMIM: 610732) PREDICTED: tetratricop ( 777) 242 60.4 1.3e-08
NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 239 59.7 1.4e-08
NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 239 59.7 1.4e-08
XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 239 59.7 1.5e-08
NP_055635 (OMIM: 606081) mitochondrial import rece ( 608) 233 58.5 4e-08
XP_011520081 (OMIM: 611219) PREDICTED: protein unc ( 944) 228 57.5 1.2e-07
NP_001310548 (OMIM: 611219) protein unc-45 homolog ( 944) 228 57.5 1.2e-07
NP_061141 (OMIM: 611219) protein unc-45 homolog A ( 944) 228 57.5 1.2e-07
NP_071393 (OMIM: 617076) FK506-binding protein-lik ( 349) 222 56.0 1.2e-07
NP_005852 (OMIM: 607207,615768) E3 ubiquitin-prote ( 303) 215 54.5 3e-07
NP_001305462 (OMIM: 610732) tetratricopeptide repe ( 711) 220 55.8 3.1e-07
NP_001310550 (OMIM: 611219) protein unc-45 homolog ( 929) 219 55.6 4.5e-07
NP_001034764 (OMIM: 611219) protein unc-45 homolog ( 929) 219 55.6 4.5e-07
NP_001295210 (OMIM: 611220,616279) protein unc-45 ( 850) 218 55.4 4.8e-07
XP_016879723 (OMIM: 611220,616279) PREDICTED: prot ( 850) 218 55.4 4.8e-07
NP_001028748 (OMIM: 611220,616279) protein unc-45 ( 929) 218 55.4 5.2e-07
NP_001253981 (OMIM: 611220,616279) protein unc-45 ( 929) 218 55.4 5.2e-07
NP_775259 (OMIM: 611220,616279) protein unc-45 hom ( 931) 218 55.4 5.2e-07
NP_001269582 (OMIM: 605063) stress-induced-phospho ( 519) 214 54.4 5.6e-07
NP_006810 (OMIM: 605063) stress-induced-phosphopro ( 543) 214 54.4 5.8e-07
NP_001269581 (OMIM: 605063) stress-induced-phospho ( 590) 214 54.5 6.2e-07
XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 199 51.2 4.1e-06
NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 199 51.3 4.5e-06
>>NP_006800 (OMIM: 616049) mitochondrial import receptor (309 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 2284.3 bits: 430.8 E(85289): 1.7e-120
Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKL
250 260 270 280 290 300
pF1KE1 RQEVKQNLH
:::::::::
NP_006 RQEVKQNLH
>>XP_011526803 (OMIM: 616049) PREDICTED: mitochondrial i (283 aa)
initn: 1747 init1: 1747 opt: 1749 Z-score: 1992.2 bits: 376.6 E(85289): 3.2e-104
Smith-Waterman score: 1749; 96.8% identity (98.9% similar) in 278 aa overlap (32-309:6-283)
10 20 30 40 50 60
pF1KE1 APKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACH
: .. :.:. ..::::::::::::::::::
XP_011 MKDIKYQHGNRILSEKSSSDPEEESVLYSNRAACH
10 20 30
70 80 90 100 110 120
pF1KE1 LKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 VEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 NRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 QYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLR
220 230 240 250 260 270
pF1KE1 QEVKQNLH
::::::::
XP_011 QEVKQNLH
280
>>XP_005260311 (OMIM: 616049) PREDICTED: mitochondrial i (207 aa)
initn: 1330 init1: 1330 opt: 1330 Z-score: 1518.8 bits: 288.6 E(85289): 7.4e-78
Smith-Waterman score: 1330; 100.0% identity (100.0% similar) in 207 aa overlap (103-309:1-207)
80 90 100 110 120 130
pF1KE1 DCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRAL
::::::::::::::::::::::::::::::
XP_005 MAYVDYKTVLQIDDNVTSAVEGINRMTRAL
10 20 30
140 150 160 170 180 190
pF1KE1 MDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEK
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 ARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTE
100 110 120 130 140 150
260 270 280 290 300
pF1KE1 ALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH
160 170 180 190 200
>>XP_016883089 (OMIM: 616049) PREDICTED: mitochondrial i (190 aa)
initn: 1206 init1: 1206 opt: 1206 Z-score: 1378.7 bits: 262.5 E(85289): 4.7e-70
Smith-Waterman score: 1206; 98.9% identity (98.9% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL
::: ::
XP_016 KNREHSAIWS
190
>>XP_016869244 (OMIM: 603395,615505) PREDICTED: sperm-as (814 aa)
initn: 879 init1: 546 opt: 895 Z-score: 1016.0 bits: 197.5 E(85289): 7.5e-50
Smith-Waterman score: 895; 48.8% identity (73.2% similar) in 299 aa overlap (12-309:336-627)
10 20 30 40
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQA
:.. ::: ::.::.:::.. :. :. .:.
XP_016 SPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEP
310 320 330 340 350 360
50 60 70 80 90 100
pF1KE1 QGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKY
:: .. :.::::::::.::.::: ::.::. :: : :::.::::::: :::.::.:
XP_016 AGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQY
370 380 390 400 410 420
110 120 130 140 150 160
pF1KE1 PMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ-KRWNS
:::::::::::: .. : ...::..: ::. ::.:: :: :: ::.:. . :.
XP_016 GKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWH-
430 440 450 460 470 480
170 180 190 200 210 220
pF1KE1 LPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL
:. ::: .... .... .: . : . ..::::::. :. :.: :. :::: :
XP_016 -PA---KEMISKQAGDSSS--HRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECL
490 500 510 520 530
230 240 250 260 270 280
pF1KE1 LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSS
.: : : :.::::::: : :. :: .:: .::.: ::::::::: :::.::.:..:
XP_016 KINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKS
540 550 560 570 580 590
290 300
pF1KE1 FADISNLLQIEPRNGPAQKLRQEVKQNLH
. :..... ..: :. .:: . :.
XP_016 LIDLNKVILLDPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGR
600 610 620 630 640 650
>--
initn: 336 init1: 170 opt: 255 Z-score: 289.8 bits: 63.1 E(85289): 2.1e-09
Smith-Waterman score: 255; 31.8% identity (68.2% similar) in 151 aa overlap (164-308:63-211)
140 150 160 170 180 190
pF1KE1 DSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKA
:..:: . ... . ..:. .:: .::
XP_016 YSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAGLTEKE
40 50 60 70 80 90
200 210 220 230 240
pF1KE1 RVL-----KEEGNELVKKGNHKKAIEKYSESLLCSNLESAT-YSNRALCYLVLKQYTEAV
. . ::.::: ..:....:. :..:. : : ... :.::: . :.... :
XP_016 KDFLATREKEKGNEAFNSGDYEEAVMYYTRSI--SALPTVVAYNNRAQAEIKLQNWNSAF
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 KDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQN
.:: ..:.:. ::::. ::: ..: . . . :.:..:..:: : :.: .::...
XP_016 QDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERD
160 170 180 190 200 210
pF1KE1 LH
:
XP_016 LKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVM
220 230 240 250 260 270
>>XP_011515545 (OMIM: 603395,615505) PREDICTED: sperm-as (926 aa)
initn: 879 init1: 546 opt: 895 Z-score: 1015.1 bits: 197.5 E(85289): 8.4e-50
Smith-Waterman score: 895; 48.8% identity (73.2% similar) in 299 aa overlap (12-309:448-739)
10 20 30 40
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQA
:.. ::: ::.::.:::.. :. :. .:.
XP_011 SPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEP
420 430 440 450 460 470
50 60 70 80 90 100
pF1KE1 QGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKY
:: .. :.::::::::.::.::: ::.::. :: : :::.::::::: :::.::.:
XP_011 AGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQY
480 490 500 510 520 530
110 120 130 140 150 160
pF1KE1 PMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ-KRWNS
:::::::::::: .. : ...::..: ::. ::.:: :: :: ::.:. . :.
XP_011 GKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWH-
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE1 LPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL
:. ::: .... .... .: . : . ..::::::. :. :.: :. :::: :
XP_011 -PA---KEMISKQAGDSSS--HRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECL
600 610 620 630 640 650
230 240 250 260 270 280
pF1KE1 LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSS
.: : : :.::::::: : :. :: .:: .::.: ::::::::: :::.::.:..:
XP_011 KINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKS
660 670 680 690 700 710
290 300
pF1KE1 FADISNLLQIEPRNGPAQKLRQEVKQNLH
. :..... ..: :. .:: . :.
XP_011 LIDLNKVILLDPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGR
720 730 740 750 760 770
>--
initn: 308 init1: 170 opt: 258 Z-score: 292.3 bits: 63.8 E(85289): 1.5e-09
Smith-Waterman score: 258; 27.7% identity (59.8% similar) in 224 aa overlap (99-308:109-323)
70 80 90 100 110 120
pF1KE1 DCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRM
:. : . . .: . ::. :.: :
XP_011 KPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPP-VRGSNSC
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE1 TRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLP--------SENHKEMAKSKSKETTAT
. .: : : :. .: . . :... .:..:: . ... .
XP_011 LH-----VGKEKYSKRPTKKKTPRDYAE-WDKFDVEKECLKIDEDYKEKTVIDKSHLSKI
140 150 160 170 180 190
190 200 210 220 230
pF1KE1 KNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSESLLCSNLESAT-YSNRA
..:. .:: .:: . . ::.::: ..:....:. :..:. : : ... :.:::
XP_011 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI--SALPTVVAYNNRA
200 210 220 230 240
240 250 260 270 280 290
pF1KE1 LCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN
. :.... : .:: ..:.:. ::::. ::: ..: . . . :.:..:..:: :
XP_011 QAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDN
250 260 270 280 290 300
300
pF1KE1 GPAQKLRQEVKQNLH
:.: .::...:
XP_011 DLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAE
310 320 330 340 350 360
>>XP_011515544 (OMIM: 603395,615505) PREDICTED: sperm-as (926 aa)
initn: 879 init1: 546 opt: 895 Z-score: 1015.1 bits: 197.5 E(85289): 8.4e-50
Smith-Waterman score: 895; 48.8% identity (73.2% similar) in 299 aa overlap (12-309:448-739)
10 20 30 40
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQA
:.. ::: ::.::.:::.. :. :. .:.
XP_011 SPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEP
420 430 440 450 460 470
50 60 70 80 90 100
pF1KE1 QGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKY
:: .. :.::::::::.::.::: ::.::. :: : :::.::::::: :::.::.:
XP_011 AGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQY
480 490 500 510 520 530
110 120 130 140 150 160
pF1KE1 PMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ-KRWNS
:::::::::::: .. : ...::..: ::. ::.:: :: :: ::.:. . :.
XP_011 GKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWH-
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE1 LPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL
:. ::: .... .... .: . : . ..::::::. :. :.: :. :::: :
XP_011 -PA---KEMISKQAGDSSS--HRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECL
600 610 620 630 640 650
230 240 250 260 270 280
pF1KE1 LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSS
.: : : :.::::::: : :. :: .:: .::.: ::::::::: :::.::.:..:
XP_011 KINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKS
660 670 680 690 700 710
290 300
pF1KE1 FADISNLLQIEPRNGPAQKLRQEVKQNLH
. :..... ..: :. .:: . :.
XP_011 LIDLNKVILLDPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGR
720 730 740 750 760 770
>--
initn: 308 init1: 170 opt: 258 Z-score: 292.3 bits: 63.8 E(85289): 1.5e-09
Smith-Waterman score: 258; 27.7% identity (59.8% similar) in 224 aa overlap (99-308:109-323)
70 80 90 100 110 120
pF1KE1 DCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRM
:. : . . .: . ::. :.: :
XP_011 KPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPP-VRGSNSC
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE1 TRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLP--------SENHKEMAKSKSKETTAT
. .: : : :. .: . . :... .:..:: . ... .
XP_011 LH-----VGKEKYSKRPTKKKTPRDYAE-WDKFDVEKECLKIDEDYKEKTVIDKSHLSKI
140 150 160 170 180 190
190 200 210 220 230
pF1KE1 KNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSESLLCSNLESAT-YSNRA
..:. .:: .:: . . ::.::: ..:....:. :..:. : : ... :.:::
XP_011 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI--SALPTVVAYNNRA
200 210 220 230 240
240 250 260 270 280 290
pF1KE1 LCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN
. :.... : .:: ..:.:. ::::. ::: ..: . . . :.:..:..:: :
XP_011 QAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDN
250 260 270 280 290 300
300
pF1KE1 GPAQKLRQEVKQNLH
:.: .::...:
XP_011 DLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAE
310 320 330 340 350 360
>>NP_757367 (OMIM: 603395,615505) sperm-associated antig (926 aa)
initn: 879 init1: 546 opt: 895 Z-score: 1015.1 bits: 197.5 E(85289): 8.4e-50
Smith-Waterman score: 895; 48.8% identity (73.2% similar) in 299 aa overlap (12-309:448-739)
10 20 30 40
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQA
:.. ::: ::.::.:::.. :. :. .:.
NP_757 SPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEP
420 430 440 450 460 470
50 60 70 80 90 100
pF1KE1 QGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKY
:: .. :.::::::::.::.::: ::.::. :: : :::.::::::: :::.::.:
NP_757 AGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQY
480 490 500 510 520 530
110 120 130 140 150 160
pF1KE1 PMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ-KRWNS
:::::::::::: .. : ...::..: ::. ::.:: :: :: ::.:. . :.
NP_757 GKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWH-
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE1 LPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL
:. ::: .... .... .: . : . ..::::::. :. :.: :. :::: :
NP_757 -PA---KEMISKQAGDSSS--HRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECL
600 610 620 630 640 650
230 240 250 260 270 280
pF1KE1 LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSS
.: : : :.::::::: : :. :: .:: .::.: ::::::::: :::.::.:..:
NP_757 KINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKS
660 670 680 690 700 710
290 300
pF1KE1 FADISNLLQIEPRNGPAQKLRQEVKQNLH
. :..... ..: :. .:: . :.
NP_757 LIDLNKVILLDPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGR
720 730 740 750 760 770
>--
initn: 308 init1: 170 opt: 258 Z-score: 292.3 bits: 63.8 E(85289): 1.5e-09
Smith-Waterman score: 258; 27.7% identity (59.8% similar) in 224 aa overlap (99-308:109-323)
70 80 90 100 110 120
pF1KE1 DCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRM
:. : . . .: . ::. :.: :
NP_757 KPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPP-VRGSNSC
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE1 TRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLP--------SENHKEMAKSKSKETTAT
. .: : : :. .: . . :... .:..:: . ... .
NP_757 LH-----VGKEKYSKRPTKKKTPRDYAE-WDKFDVEKECLKIDEDYKEKTVIDKSHLSKI
140 150 160 170 180 190
190 200 210 220 230
pF1KE1 KNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSESLLCSNLESAT-YSNRA
..:. .:: .:: . . ::.::: ..:....:. :..:. : : ... :.:::
NP_757 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI--SALPTVVAYNNRA
200 210 220 230 240
240 250 260 270 280 290
pF1KE1 LCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN
. :.... : .:: ..:.:. ::::. ::: ..: . . . :.:..:..:: :
NP_757 QAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDN
250 260 270 280 290 300
300
pF1KE1 GPAQKLRQEVKQNLH
:.: .::...:
NP_757 DLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAE
310 320 330 340 350 360
>>NP_003105 (OMIM: 603395,615505) sperm-associated antig (926 aa)
initn: 879 init1: 546 opt: 895 Z-score: 1015.1 bits: 197.5 E(85289): 8.4e-50
Smith-Waterman score: 895; 48.8% identity (73.2% similar) in 299 aa overlap (12-309:448-739)
10 20 30 40
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQA
:.. ::: ::.::.:::.. :. :. .:.
NP_003 SPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEP
420 430 440 450 460 470
50 60 70 80 90 100
pF1KE1 QGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKY
:: .. :.::::::::.::.::: ::.::. :: : :::.::::::: :::.::.:
NP_003 AGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQY
480 490 500 510 520 530
110 120 130 140 150 160
pF1KE1 PMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ-KRWNS
:::::::::::: .. : ...::..: ::. ::.:: :: :: ::.:. . :.
NP_003 GKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWH-
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE1 LPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL
:. ::: .... .... .: . : . ..::::::. :. :.: :. :::: :
NP_003 -PA---KEMISKQAGDSSS--HRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECL
600 610 620 630 640 650
230 240 250 260 270 280
pF1KE1 LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSS
.: : : :.::::::: : :. :: .:: .::.: ::::::::: :::.::.:..:
NP_003 KINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKS
660 670 680 690 700 710
290 300
pF1KE1 FADISNLLQIEPRNGPAQKLRQEVKQNLH
. :..... ..: :. .:: . :.
NP_003 LIDLNKVILLDPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGR
720 730 740 750 760 770
>--
initn: 308 init1: 170 opt: 258 Z-score: 292.3 bits: 63.8 E(85289): 1.5e-09
Smith-Waterman score: 258; 27.7% identity (59.8% similar) in 224 aa overlap (99-308:109-323)
70 80 90 100 110 120
pF1KE1 DCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRM
:. : . . .: . ::. :.: :
NP_003 KPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPP-VRGSNSC
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE1 TRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLP--------SENHKEMAKSKSKETTAT
. .: : : :. .: . . :... .:..:: . ... .
NP_003 LH-----VGKEKYSKRPTKKKTPRDYAE-WDKFDVEKECLKIDEDYKEKTVIDKSHLSKI
140 150 160 170 180 190
190 200 210 220 230
pF1KE1 KNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSESLLCSNLESAT-YSNRA
..:. .:: .:: . . ::.::: ..:....:. :..:. : : ... :.:::
NP_003 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI--SALPTVVAYNNRA
200 210 220 230 240
240 250 260 270 280 290
pF1KE1 LCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN
. :.... : .:: ..:.:. ::::. ::: ..: . . . :.:..:..:: :
NP_003 QAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDN
250 260 270 280 290 300
300
pF1KE1 GPAQKLRQEVKQNLH
:.: .::...:
NP_003 DLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAE
310 320 330 340 350 360
>>XP_016869243 (OMIM: 603395,615505) PREDICTED: sperm-as (961 aa)
initn: 879 init1: 546 opt: 895 Z-score: 1014.9 bits: 197.5 E(85289): 8.6e-50
Smith-Waterman score: 895; 48.8% identity (73.2% similar) in 299 aa overlap (12-309:483-774)
10 20 30 40
pF1KE1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQA
:.. ::: ::.::.:::.. :. :. .:.
XP_016 SPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEP
460 470 480 490 500 510
50 60 70 80 90 100
pF1KE1 QGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKY
:: .. :.::::::::.::.::: ::.::. :: : :::.::::::: :::.::.:
XP_016 AGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQY
520 530 540 550 560 570
110 120 130 140 150 160
pF1KE1 PMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ-KRWNS
:::::::::::: .. : ...::..: ::. ::.:: :: :: ::.:. . :.
XP_016 GKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWH-
580 590 600 610 620 630
170 180 190 200 210 220
pF1KE1 LPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL
:. ::: .... .... .: . : . ..::::::. :. :.: :. :::: :
XP_016 -PA---KEMISKQAGDSSS--HRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECL
640 650 660 670 680
230 240 250 260 270 280
pF1KE1 LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSS
.: : : :.::::::: : :. :: .:: .::.: ::::::::: :::.::.:..:
XP_016 KINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKS
690 700 710 720 730 740
290 300
pF1KE1 FADISNLLQIEPRNGPAQKLRQEVKQNLH
. :..... ..: :. .:: . :.
XP_016 LIDLNKVILLDPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGR
750 760 770 780 790 800
>--
initn: 316 init1: 170 opt: 258 Z-score: 292.1 bits: 63.8 E(85289): 1.6e-09
Smith-Waterman score: 258; 27.7% identity (59.8% similar) in 224 aa overlap (99-308:144-358)
70 80 90 100 110 120
pF1KE1 DCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRM
:. : . . .: . ::. :.: :
XP_016 KPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPP-VRGSNSC
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE1 TRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLP--------SENHKEMAKSKSKETTAT
. .: : : :. .: . . :... .:..:: . ... .
XP_016 LH-----VGKEKYSKRPTKKKTPRDYAE-WDKFDVEKECLKIDEDYKEKTVIDKSHLSKI
180 190 200 210 220
190 200 210 220 230
pF1KE1 KNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSESLLCSNLESAT-YSNRA
..:. .:: .:: . . ::.::: ..:....:. :..:. : : ... :.:::
XP_016 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI--SALPTVVAYNNRA
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE1 LCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN
. :.... : .:: ..:.:. ::::. ::: ..: . . . :.:..:..:: :
XP_016 QAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDN
290 300 310 320 330 340
300
pF1KE1 GPAQKLRQEVKQNLH
:.: .::...:
XP_016 DLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAE
350 360 370 380 390 400
309 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:23:48 2016 done: Mon Nov 7 01:23:49 2016
Total Scan time: 6.350 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]