Result of FASTA (omim) for
pFN21AB6957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6957, 213 aa
1>>>pF1KB6957 213 - 213 aa - 213 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7057+/-0.00026; mu= 13.5854+/- 0.016
mean_var=93.4145+/-18.318, 0's: 0 Z-trim(121.8): 102 B-trim: 27 in 1/58
Lambda= 0.132699
statistics sampled from 38875 (38984) to 38875 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.457), width: 16
Scan time: 6.230
The best scores are: opt bits E(85289)
NP_064455 (OMIM: 146770,613500) immunoglobulin lam ( 213) 1461 288.7 4.9e-78
XP_011528471 (OMIM: 146770,613500) PREDICTED: immu ( 214) 1449 286.4 2.4e-77
NP_690594 (OMIM: 146770,613500) immunoglobulin lam ( 84) 479 100.4 9.4e-22
NP_072049 (OMIM: 612735) major histocompatibility ( 266) 187 44.9 0.00015
NP_002116 (OMIM: 604776) major histocompatibility ( 266) 182 43.9 0.0003
XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276) 182 43.9 0.0003
XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA ( 206) 180 43.4 0.00032
NP_002113 (OMIM: 146880,212750) HLA class II histo ( 255) 180 43.5 0.00037
XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266) 179 43.3 0.00044
NP_002110 (OMIM: 142930) HLA class II histocompati ( 250) 178 43.1 0.00048
NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266) 173 42.2 0.00098
NP_064440 (OMIM: 613503) HLA class II histocompati ( 255) 171 41.8 0.0012
NP_291032 (OMIM: 142880) HLA class II histocompati ( 260) 171 41.8 0.0012
NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260) 171 41.8 0.0012
NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260) 171 41.8 0.0012
NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266) 169 41.4 0.0017
NP_002112 (OMIM: 142858) HLA class II histocompati ( 258) 163 40.2 0.0036
NP_061984 (OMIM: 142860) HLA class II histocompati ( 254) 156 38.9 0.009
>>NP_064455 (OMIM: 146770,613500) immunoglobulin lambda- (213 aa)
initn: 1461 init1: 1461 opt: 1461 Z-score: 1522.0 bits: 288.7 E(85289): 4.9e-78
Smith-Waterman score: 1461; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213)
10 20 30 40 50 60
pF1KB6 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLS
130 140 150 160 170 180
190 200 210
pF1KB6 LTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
:::::::::::::::::::::::::::::::::
NP_064 LTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
190 200 210
>>XP_011528471 (OMIM: 146770,613500) PREDICTED: immunogl (214 aa)
initn: 989 init1: 989 opt: 1449 Z-score: 1509.6 bits: 286.4 E(85289): 2.4e-77
Smith-Waterman score: 1449; 99.5% identity (99.5% similar) in 214 aa overlap (1-213:1-214)
10 20 30 40 50 60
pF1KB6 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 SSLRSRWG-RFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLF
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLRSRWGSRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 PPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYL
130 140 150 160 170 180
180 190 200 210
pF1KB6 SLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
::::::::::::::::::::::::::::::::::
XP_011 SLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
190 200 210
>>NP_690594 (OMIM: 146770,613500) immunoglobulin lambda- (84 aa)
initn: 479 init1: 479 opt: 479 Z-score: 511.5 bits: 100.4 E(85289): 9.4e-22
Smith-Waterman score: 479; 100.0% identity (100.0% similar) in 69 aa overlap (1-69:1-69)
10 20 30 40 50 60
pF1KB6 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFP
:::::::::
NP_690 SSLRSRWGRSAQGHPLGHSVPAVL
70 80
>>NP_072049 (OMIM: 612735) major histocompatibility comp (266 aa)
initn: 149 init1: 81 opt: 187 Z-score: 202.6 bits: 44.9 E(85289): 0.00015
Smith-Waterman score: 187; 32.8% identity (56.9% similar) in 116 aa overlap (92-207:106-215)
70 80 90 100 110 120
pF1KB6 SLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPP
: : .: : ..:: : .. :.::..:
NP_072 YRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV--QRRVHPQVTVYPA
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB6 SSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSL
... :: .. ::: .. :::: . : : .: :: : .... . . .:
NP_072 KTQPLQ-HHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLET
140 150 160 170 180 190
190 200 210
pF1KB6 TPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
.: :: . :.::: : . : ::
NP_072 VP---RSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIY
200 210 220 230 240
>>NP_002116 (OMIM: 604776) major histocompatibility comp (266 aa)
initn: 140 init1: 79 opt: 182 Z-score: 197.4 bits: 43.9 E(85289): 0.0003
Smith-Waterman score: 182; 33.0% identity (57.1% similar) in 112 aa overlap (96-207:110-215)
70 80 90 100 110 120
pF1KB6 RWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEE
: .: : ..:: : .. :.::..: ..
NP_002 TELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV--QRRVEPKVTVYPARTQT
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB6 LQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQ
:: .. ::: .: :::: . : : .. :: : .... . . .: .:
NP_002 LQ-HHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVP--
140 150 160 170 180 190
190 200 210
pF1KB6 WRSRRSYSCQVMHEGSTVEKTVAPAECS
:: . :.::: : . : ::
NP_002 -RSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQ
200 210 220 230 240 250
>>XP_011512864 (OMIM: 604776) PREDICTED: major histocomp (276 aa)
initn: 140 init1: 79 opt: 182 Z-score: 197.2 bits: 43.9 E(85289): 0.0003
Smith-Waterman score: 182; 33.0% identity (57.1% similar) in 112 aa overlap (96-207:110-215)
70 80 90 100 110 120
pF1KB6 RWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEE
: .: : ..:: : .. :.::..: ..
XP_011 TELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV--QRRVEPKVTVYPARTQT
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB6 LQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQ
:: .. ::: .: :::: . : : .. :: : .... . . .: .:
XP_011 LQ-HHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVP--
140 150 160 170 180 190
190 200 210
pF1KB6 WRSRRSYSCQVMHEGSTVEKTVAPAECS
:: . :.::: : . : ::
XP_011 -RSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQ
200 210 220 230 240 250
>>XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA clas (206 aa)
initn: 176 init1: 142 opt: 180 Z-score: 196.8 bits: 43.4 E(85289): 0.00032
Smith-Waterman score: 180; 34.1% identity (65.9% similar) in 88 aa overlap (114-200:113-195)
90 100 110 120 130 140
pF1KB6 PRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEEL-QANKATLVCLMNDFYP
: ::.: : : : : ::.::.....:
XP_006 QGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVTLGQPN--TLICLVDNIFP
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB6 GILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST
....:: ..: .:.:: :. ..:.... :::.. : . . :.:.: : :
XP_006 PVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLP---SADEIYDCKVEHWGLD
150 160 170 180 190
210
pF1KB6 VEKTVAPAECS
XP_006 QPLLKHWVE
200
>>NP_002113 (OMIM: 146880,212750) HLA class II histocomp (255 aa)
initn: 176 init1: 142 opt: 180 Z-score: 195.6 bits: 43.5 E(85289): 0.00037
Smith-Waterman score: 180; 34.1% identity (65.9% similar) in 88 aa overlap (114-200:113-195)
90 100 110 120 130 140
pF1KB6 PRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEEL-QANKATLVCLMNDFYP
: ::.: : : : : ::.::.....:
NP_002 QGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVTLGQPN--TLICLVDNIFP
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB6 GILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST
....:: ..: .:.:: :. ..:.... :::.. : . . :.:.: : :
NP_002 PVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLP---SADEIYDCKVEHWGLD
150 160 170 180 190
210
pF1KB6 VEKTVAPAECS
NP_002 QPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFIIQGLRSVGASRHQGPL
200 210 220 230 240 250
>>XP_011546040 (OMIM: 126200,142857,180300,181000) PREDI (266 aa)
initn: 138 init1: 81 opt: 179 Z-score: 194.3 bits: 43.3 E(85289): 0.00044
Smith-Waterman score: 179; 29.8% identity (58.1% similar) in 124 aa overlap (76-198:89-206)
50 60 70 80 90 100
pF1KB6 QSRALGPGAPGGSSRSSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVT-HVFGSGTQL
::.. . . ... ..: : .: : ..
XP_011 LFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 TVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTT
:: : .. : ::..: ... :: .. ::: .. :::: . : : .: :: :
XP_011 TV--QRRVHPEVTVYPAKTQPLQ-HHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTG
120 130 140 150 160 170
170 180 190 200 210
pF1KB6 PSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
.... . . .: .: :: . :.::: :
XP_011 LIQNGDWTFQTLVMLETVP---RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGV
180 190 200 210 220 230
XP_011 GGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
240 250 260
>>NP_002110 (OMIM: 142930) HLA class II histocompatibili (250 aa)
initn: 113 init1: 73 opt: 178 Z-score: 193.6 bits: 43.1 E(85289): 0.00048
Smith-Waterman score: 178; 33.0% identity (63.6% similar) in 88 aa overlap (114-200:113-195)
90 100 110 120 130 140
pF1KB6 PRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEEL-QANKATLVCLMNDFYP
: ::..: : :: : : :.:......:
NP_002 QGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELGQPN--ILICIVDNIFP
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB6 GILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST
....:: .: .:.:: .:. .: .. . :: ..: .. :.::: : :
NP_002 PVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVP---SAEDVYDCQVEHWGLD
150 160 170 180 190
210
pF1KB6 VEKTVAPAECS
NP_002 APLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR
200 210 220 230 240 250
213 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:22:31 2016 done: Fri Nov 4 11:22:32 2016
Total Scan time: 6.230 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]