Result of FASTA (omim) for
pFN21AE1315
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1315, 309 aa
1>>>pF1KE1315 309 - 309 aa - 309 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8182+/-0.000444; mu= 18.0639+/- 0.028
mean_var=70.0560+/-14.194, 0's: 0 Z-trim(109.4): 248 B-trim: 15 in 1/47
Lambda= 0.153233
statistics sampled from 17251 (17540) to 17251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.571), E-opt: 0.2 (0.206), width: 16
Scan time: 6.540
The best scores are: opt bits E(85289)
NP_003346 (OMIM: 601693,607447) mitochondrial unco ( 309) 2007 453.2 3e-127
NP_003347 (OMIM: 601665,602044) mitochondrial unco ( 312) 1476 335.9 6.5e-92
NP_073714 (OMIM: 601665,602044) mitochondrial unco ( 275) 1279 292.3 7.6e-79
XP_005263263 (OMIM: 113730,601665) PREDICTED: mito ( 306) 1197 274.2 2.4e-73
NP_068605 (OMIM: 113730,601665) mitochondrial brow ( 307) 1191 272.8 5.9e-73
XP_011530530 (OMIM: 113730,601665) PREDICTED: mito ( 277) 1055 242.7 6.2e-64
NP_001269127 (OMIM: 300242) brain mitochondrial ca ( 290) 684 160.7 3.1e-39
NP_001269125 (OMIM: 300242) brain mitochondrial ca ( 322) 684 160.8 3.4e-39
NP_001269124 (OMIM: 300242) brain mitochondrial ca ( 325) 684 160.8 3.4e-39
XP_011529704 (OMIM: 300242) PREDICTED: brain mitoc ( 334) 684 160.8 3.5e-39
XP_016876013 (OMIM: 610793) PREDICTED: kidney mito ( 291) 675 158.8 1.2e-38
NP_001010875 (OMIM: 610793) kidney mitochondrial c ( 291) 675 158.8 1.2e-38
XP_016885425 (OMIM: 300242) PREDICTED: brain mitoc ( 306) 641 151.3 2.4e-36
XP_016885428 (OMIM: 300242) PREDICTED: brain mitoc ( 338) 641 151.3 2.5e-36
XP_016885427 (OMIM: 300242) PREDICTED: brain mitoc ( 341) 641 151.3 2.6e-36
XP_016885426 (OMIM: 300242) PREDICTED: brain mitoc ( 350) 641 151.3 2.6e-36
NP_004268 (OMIM: 613725) mitochondrial uncoupling ( 323) 613 145.1 1.8e-34
NP_036272 (OMIM: 606794) mitochondrial dicarboxyla ( 287) 576 136.9 4.8e-32
NP_001273735 (OMIM: 610793) kidney mitochondrial c ( 240) 575 136.6 4.9e-32
NP_001190980 (OMIM: 613725) mitochondrial uncoupli ( 300) 566 134.7 2.3e-31
XP_005249540 (OMIM: 613725) PREDICTED: mitochondri ( 310) 566 134.7 2.3e-31
XP_005262546 (OMIM: 300242) PREDICTED: brain mitoc ( 224) 542 129.3 7.3e-30
NP_003553 (OMIM: 604165) mitochondrial 2-oxoglutar ( 314) 537 128.3 2e-29
NP_001273736 (OMIM: 610793) kidney mitochondrial c ( 216) 530 126.6 4.5e-29
XP_011533329 (OMIM: 610793) PREDICTED: kidney mito ( 216) 530 126.6 4.5e-29
XP_016879709 (OMIM: 606794) PREDICTED: mitochondri ( 244) 528 126.2 6.6e-29
XP_005266379 (OMIM: 610793) PREDICTED: kidney mito ( 254) 521 124.7 2e-28
XP_016876012 (OMIM: 610793) PREDICTED: kidney mito ( 293) 519 124.3 3e-28
XP_005266378 (OMIM: 610793) PREDICTED: kidney mito ( 293) 519 124.3 3e-28
XP_006719856 (OMIM: 610793) PREDICTED: kidney mito ( 293) 519 124.3 3e-28
XP_006719857 (OMIM: 610793) PREDICTED: kidney mito ( 293) 519 124.3 3e-28
NP_001158889 (OMIM: 604165) mitochondrial 2-oxoglu ( 303) 509 122.1 1.4e-27
XP_016885429 (OMIM: 300242) PREDICTED: brain mitoc ( 240) 499 119.8 5.6e-27
NP_997231 (OMIM: 610817) solute carrier family 25 ( 304) 476 114.8 2.2e-25
NP_001158890 (OMIM: 604165) mitochondrial 2-oxoglu ( 263) 440 106.8 5e-23
XP_016885431 (OMIM: 300242) PREDICTED: brain mitoc ( 197) 428 104.0 2.6e-22
XP_016885430 (OMIM: 300242) PREDICTED: brain mitoc ( 197) 428 104.0 2.6e-22
NP_001190981 (OMIM: 613725) mitochondrial uncoupli ( 245) 417 101.7 1.6e-21
XP_016885432 (OMIM: 300242) PREDICTED: brain mitoc ( 157) 396 96.8 2.9e-20
XP_016867001 (OMIM: 613725) PREDICTED: mitochondri ( 195) 377 92.7 6.3e-19
XP_011533328 (OMIM: 610793) PREDICTED: kidney mito ( 218) 374 92.1 1.1e-18
XP_011539595 (OMIM: 610817) PREDICTED: solute carr ( 251) 374 92.2 1.2e-18
XP_011539594 (OMIM: 610817) PREDICTED: solute carr ( 256) 373 91.9 1.4e-18
NP_005975 (OMIM: 190315,615182) tricarboxylate tra ( 311) 370 91.4 2.6e-18
NP_001243463 (OMIM: 190315,615182) tricarboxylate ( 318) 364 90.0 6.6e-18
XP_011529705 (OMIM: 300242) PREDICTED: brain mitoc ( 205) 357 88.3 1.4e-17
NP_001269126 (OMIM: 300242) brain mitochondrial ca ( 353) 357 88.5 2.1e-17
XP_016856572 (OMIM: 610817) PREDICTED: solute carr ( 259) 330 82.4 1e-15
XP_011522148 (OMIM: 610818) PREDICTED: solute carr ( 291) 330 82.5 1.1e-15
NP_958928 (OMIM: 610818) solute carrier family 25 ( 295) 330 82.5 1.1e-15
>>NP_003346 (OMIM: 601693,607447) mitochondrial uncoupli (309 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 2405.6 bits: 453.2 E(85289): 3e-127
Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMA
250 260 270 280 290 300
pF1KE1 ACTSREAPF
:::::::::
NP_003 ACTSREAPF
>>NP_003347 (OMIM: 601665,602044) mitochondrial uncoupli (312 aa)
initn: 1412 init1: 778 opt: 1476 Z-score: 1771.1 bits: 335.9 E(85289): 6.5e-92
Smith-Waterman score: 1476; 72.2% identity (87.5% similar) in 313 aa overlap (1-309:1-312)
10 20 30 40 50 60
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
:::.: .::::: .:::::::::::.:::.::::::::::::::::.:. :... .:::
NP_003 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQA-VQTARLVQYR
10 20 30 40 50
70 80 90 100 110
pF1KE1 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHASIGSR
::.:::::::::::: : ::::::::::::::::.:::::::::: :: ::....:. .:
NP_003 GVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAG---GGRRYQSTVNAYKTIAREEGFRGLW
.::: ::::.::. :::::::::::::. . : . :.:..:..::.::::::: ::::
NP_003 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVD
::: ::. :::::::::.::::..:. :: .:.::..::::.::::::::.::.:::::
NP_003 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 VVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR
::::::::: ::: : : . :. .::: :::::: ::::::::::::::::::::::
NP_003 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR
240 250 260 270 280 290
300
pF1KE1 ALMAACTSREAPF
::: . ::.::
NP_003 ALMKVQMLRESPF
300 310
>>NP_073714 (OMIM: 601665,602044) mitochondrial uncoupli (275 aa)
initn: 1215 init1: 581 opt: 1279 Z-score: 1536.5 bits: 292.3 E(85289): 7.6e-79
Smith-Waterman score: 1279; 71.0% identity (87.7% similar) in 276 aa overlap (1-272:1-275)
10 20 30 40 50 60
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
:::.: .::::: .:::::::::::.:::.::::::::::::::::.:. :... .:::
NP_073 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQA-VQTARLVQYR
10 20 30 40 50
70 80 90 100 110
pF1KE1 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHASIGSR
::.:::::::::::: : ::::::::::::::::.:::::::::: :: ::....:. .:
NP_073 GVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAG---GGRRYQSTVNAYKTIAREEGFRGLW
.::: ::::.::. :::::::::::::. . : . :.:..:..::.::::::: ::::
NP_073 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVD
::: ::. :::::::::.::::..:. :: .:.::..::::.::::::::.::.:::::
NP_073 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 VVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR
::::::::: ::: : : . :. .::: :::::
NP_073 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKG
240 250 260 270
300
pF1KE1 ALMAACTSREAPF
>>XP_005263263 (OMIM: 113730,601665) PREDICTED: mitochon (306 aa)
initn: 1299 init1: 656 opt: 1197 Z-score: 1437.9 bits: 274.2 E(85289): 2.4e-73
Smith-Waterman score: 1197; 59.5% identity (84.9% similar) in 299 aa overlap (1-298:1-295)
10 20 30 40 50 60
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
: :. :.:: :: :....:: :::.::.:::::::::::::.::: : ... .:.
XP_005 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGEC--P--TSSVIRYK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRL
::.::: ..:.::: .::.:: ::::::.: ::.::::::.:..: : :.: :.::..
XP_005 GVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETPSLGSKI
60 70 80 90 100 110
130 140 150 160 170
pF1KE1 LAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGR-RYQSTVNAYKTIAREEGFRGLWKGT
::: :::..:: ..:::.:::::.:::.. : . :: .: :::. :: ::. ::::::
XP_005 LAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 SPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVK
.::. :..:.::.:::::::.:.:..: :...::.:::..::. ::::.:...:::::::
XP_005 TPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 TRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALM
::..:: :::.:. .::. .. .::: ::.::..:::::::::::.::: .::::: :
XP_005 TRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKRELS
240 250 260 270 280 290
300
pF1KE1 AACTSREAPF
XP_005 KSRQTMDCAT
300
>>NP_068605 (OMIM: 113730,601665) mitochondrial brown fa (307 aa)
initn: 1256 init1: 656 opt: 1191 Z-score: 1430.7 bits: 272.8 E(85289): 5.9e-73
Smith-Waterman score: 1191; 59.7% identity (85.0% similar) in 300 aa overlap (1-298:1-296)
10 20 30 40 50 60
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
: :. :.:: :: :....:: :::.::.:::::::::::::.::: : ... .:.
NP_068 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGEC--P--TSSVIRYK
10 20 30 40 50
70 80 90 100 110
pF1KE1 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHA-SIGSR
::.::: ..:.::: .::.:: ::::::.: ::.::::::.:..: : :.: : :.::.
NP_068 GVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGR-RYQSTVNAYKTIAREEGFRGLWKG
.::: :::..:: ..:::.:::::.:::.. : . :: .: :::. :: ::. :::::
NP_068 ILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 TSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVV
:.::. :..:.::.:::::::.:.:..: :...::.:::..::. ::::.:...::::::
NP_068 TTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 KTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRAL
:::..:: :::.:. .::. .. .::: ::.::..:::::::::::.::: .::::: :
NP_068 KTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKREL
240 250 260 270 280 290
300
pF1KE1 MAACTSREAPF
NP_068 SKSRQTMDCAT
300
>>XP_011530530 (OMIM: 113730,601665) PREDICTED: mitochon (277 aa)
initn: 1085 init1: 520 opt: 1055 Z-score: 1268.8 bits: 242.7 E(85289): 6.2e-64
Smith-Waterman score: 1055; 57.8% identity (84.1% similar) in 277 aa overlap (1-275:1-273)
10 20 30 40 50 60
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
: :. :.:: :: :....:: :::.::.:::::::::::::.::: :. .. .:.
XP_011 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGEC--PT--SSVIRYK
10 20 30 40 50
70 80 90 100 110
pF1KE1 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHA-SIGSR
::.::: ..:.::: .::.:: ::::::.: ::.::::::.:..: : :.: : :.::.
XP_011 GVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGR-RYQSTVNAYKTIAREEGFRGLWKG
.::: :::..:: ..:::.:::::.:::.. : . :: .: :::. :: ::. :::::
XP_011 ILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 TSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVV
:.::. :..:.::.:::::::.:.:..: :...::.:::..::. ::::.:...::::::
XP_011 TTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 KTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRAL
:::..:: :::.:. .::. .. .::: ::.:: .:
XP_011 KTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGKIPHIGK
240 250 260 270
300
pF1KE1 MAACTSREAPF
>>NP_001269127 (OMIM: 300242) brain mitochondrial carrie (290 aa)
initn: 470 init1: 241 opt: 684 Z-score: 825.3 bits: 160.7 E(85289): 3.1e-39
Smith-Waterman score: 684; 38.3% identity (71.8% similar) in 287 aa overlap (17-296:9-287)
10 20 30 40 50
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRAT-ASAQY
:. .: :. .:.. :::.: .:.:::.::.: . : .:
NP_001 MSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQS---IDARFKEIKY
10 20 30 40
60 70 80 90 100 110
pF1KE1 RGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSR
::.. ... . . :: .::.:.. .: :: :.....::.:.:.:..... : ..
NP_001 RGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQ-STVNAYKTIAREEGFRGLWKG
.. : ..:... ..:.::::.:.:.::: : .: : .... : ..:: ::::.:
NP_001 MICGVVSGVISSTIANPTDVLKIRMQAQ-----GSLFQGSMIGSFIDIYQQEGTRGLWRG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 TSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVV
. :.. : ::: .:: .::. : :. ...: : . ::.:.: :. .. ..:::::
NP_001 VVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 KTRYMN--SALGQ---YSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQ
.::.:: . .:. :... : : ..:: :.:::: :..:::: ::...:.::::
NP_001 RTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQ
230 240 250 260 270 280
300
pF1KE1 LKRALMAACTSREAPF
:::
NP_001 LKRLQI
290
>>NP_001269125 (OMIM: 300242) brain mitochondrial carrie (322 aa)
initn: 470 init1: 241 opt: 684 Z-score: 824.7 bits: 160.8 E(85289): 3.4e-39
Smith-Waterman score: 684; 38.3% identity (71.8% similar) in 287 aa overlap (17-296:41-319)
10 20 30 40
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGE
:. .: :. .:.. :::.: .:.:::.::.
NP_001 FLRVKFATAAVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 SQGPVRAT-ASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQ
: . : .:::.. ... . . :: .::.:.. .: :: :.....::.:.:.:.
NP_001 S---IDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKR
80 90 100 110 120
110 120 130 140 150 160
pF1KE1 FYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQ-STVNAYK
.... : .. .. : ..:... ..:.::::.:.:.::: : .: : ....
NP_001 LFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQ-----GSLFQGSMIGSFI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 TIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGA
: ..:: ::::.:. :.. : ::: .:: .::. : :. ...: : . ::.:.:
NP_001 DIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC
190 200 210 220 230 240
230 240 250 260 270
pF1KE1 GFCTTVIASPVDVVKTRYMN--SALGQ---YSSAGHCALTMLQKEGPRAFYKGFMPSFLR
:. .. ..:::::.::.:: . .:. :... : : ..:: :.:::: :..::
NP_001 GLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLR
250 260 270 280 290 300
280 290 300
pF1KE1 LGSWNVVMFVTYEQLKRALMAACTSREAPF
:: ::...:.:::::::
NP_001 LGPWNIIFFITYEQLKRLQI
310 320
>>NP_001269124 (OMIM: 300242) brain mitochondrial carrie (325 aa)
initn: 470 init1: 241 opt: 684 Z-score: 824.7 bits: 160.8 E(85289): 3.4e-39
Smith-Waterman score: 684; 38.3% identity (71.8% similar) in 287 aa overlap (17-296:44-322)
10 20 30 40
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGE
:. .: :. .:.. :::.: .:.:::.::.
NP_001 VKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 SQGPVRAT-ASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQ
: . : .:::.. ... . . :: .::.:.. .: :: :.....::.:.:.:.
NP_001 S---IDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE1 FYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQ-STVNAYK
.... : .. .. : ..:... ..:.::::.:.:.::: : .: : ....
NP_001 LFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQ-----GSLFQGSMIGSFI
140 150 160 170 180
170 180 190 200 210 220
pF1KE1 TIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGA
: ..:: ::::.:. :.. : ::: .:: .::. : :. ...: : . ::.:.:
NP_001 DIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC
190 200 210 220 230 240
230 240 250 260 270
pF1KE1 GFCTTVIASPVDVVKTRYMN--SALGQ---YSSAGHCALTMLQKEGPRAFYKGFMPSFLR
:. .. ..:::::.::.:: . .:. :... : : ..:: :.:::: :..::
NP_001 GLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLR
250 260 270 280 290 300
280 290 300
pF1KE1 LGSWNVVMFVTYEQLKRALMAACTSREAPF
:: ::...:.:::::::
NP_001 LGPWNIIFFITYEQLKRLQI
310 320
>>XP_011529704 (OMIM: 300242) PREDICTED: brain mitochond (334 aa)
initn: 470 init1: 241 opt: 684 Z-score: 824.5 bits: 160.8 E(85289): 3.5e-39
Smith-Waterman score: 684; 38.3% identity (71.8% similar) in 287 aa overlap (17-296:53-331)
10 20 30 40
pF1KE1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGE
:. .: :. .:.. :::.: .:.:::.::.
XP_011 VSGVSKHLHCISHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQ
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE1 SQGPVRAT-ASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQ
: . : .:::.. ... . . :: .::.:.. .: :: :.....::.:.:.:.
XP_011 S---IDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKR
90 100 110 120 130
110 120 130 140 150 160
pF1KE1 FYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQ-STVNAYK
.... : .. .. : ..:... ..:.::::.:.:.::: : .: : ....
XP_011 LFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQ-----GSLFQGSMIGSFI
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 TIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGA
: ..:: ::::.:. :.. : ::: .:: .::. : :. ...: : . ::.:.:
XP_011 DIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC
200 210 220 230 240 250
230 240 250 260 270
pF1KE1 GFCTTVIASPVDVVKTRYMN--SALGQ---YSSAGHCALTMLQKEGPRAFYKGFMPSFLR
:. .. ..:::::.::.:: . .:. :... : : ..:: :.:::: :..::
XP_011 GLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLR
260 270 280 290 300 310
280 290 300
pF1KE1 LGSWNVVMFVTYEQLKRALMAACTSREAPF
:: ::...:.:::::::
XP_011 LGPWNIIFFITYEQLKRLQI
320 330
309 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:48:44 2016 done: Mon Nov 7 01:48:45 2016
Total Scan time: 6.540 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]