Result of FASTA (omim) for
pFN21AB5237
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5237, 295 aa
1>>>pF1KB5237 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3891+/-0.00041; mu= 14.8649+/- 0.025
mean_var=66.1944+/-13.004, 0's: 0 Z-trim(111.2): 48 B-trim: 124 in 1/55
Lambda= 0.157639
statistics sampled from 19668 (19714) to 19668 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.231), width: 16
Scan time: 6.580
The best scores are: opt bits E(85289)
NP_001984 (OMIM: 134390) tissue factor isoform 1 p ( 295) 1940 450.2 2.2e-126
NP_001171567 (OMIM: 134390) tissue factor isoform ( 238) 1311 307.1 2.1e-83
NP_851826 (OMIM: 606648) interleukin-22 receptor s ( 231) 225 60.1 4.6e-09
NP_851827 (OMIM: 606648) interleukin-22 receptor s ( 130) 186 51.1 1.3e-06
NP_067081 (OMIM: 605457) interleukin-22 receptor s ( 574) 178 49.6 1.7e-05
XP_016866443 (OMIM: 605620) PREDICTED: interleukin ( 554) 143 41.7 0.004
>>NP_001984 (OMIM: 134390) tissue factor isoform 1 precu (295 aa)
initn: 1940 init1: 1940 opt: 1940 Z-score: 2389.9 bits: 450.2 E(85289): 2.2e-126
Smith-Waterman score: 1940; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
190 200 210 220 230 240
250 260 270 280 290
pF1KB5 CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
250 260 270 280 290
>>NP_001171567 (OMIM: 134390) tissue factor isoform 2 pr (238 aa)
initn: 1311 init1: 1311 opt: 1311 Z-score: 1618.3 bits: 307.1 E(85289): 2.1e-83
Smith-Waterman score: 1311; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198)
10 20 30 40 50 60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
::::::::::::::::::
NP_001 KDLIYTLYYWKSSSSGKKYSTSLELWYLWSSSLSSSWLYLYTSVERQEWGRAGRRTPH
190 200 210 220 230
>>NP_851826 (OMIM: 606648) interleukin-22 receptor subun (231 aa)
initn: 162 init1: 81 opt: 225 Z-score: 283.6 bits: 60.1 E(85289): 4.6e-09
Smith-Waterman score: 225; 24.4% identity (61.1% similar) in 234 aa overlap (20-242:10-228)
10 20 30 40 50 60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
.:... .. :::...: ... . ..: ::..::.:.:
NP_851 MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPG
10 20 30 40 50
70 80 90 100 110
pF1KB5 PV----NQVYTVQISTKSG-DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAG
. ..:: :: . . .::.: :. : . ::::.: ..:... : .::
NP_851 RALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE-TSDIQEPYYGRV------
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 NVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVR-RNNTF
. :.:: .: . .:.:::. ::.. .: .... ::. .. : .. : ...
NP_851 RAASAGSYSE--WSMTPRFTPWWETKI-DPPVMNITQVNGSLLVILHAPNLPYRYQKEKN
110 120 130 140 150 160
180 190 200 210 220
pF1KB5 LSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDK---GENYCFSVQAVIPSRT
.:..: . .:.: .. ..: .. . .... .... .:: .. :
NP_851 VSIEDYY--ELLYRVFIINNSLEKEQKVYEGAHR-AVEIEALTPHSSYCVVAEIYQP--M
170 180 190 200 210
230 240 250 260 270 280
pF1KB5 VNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKEN
..:.: : .:.
NP_851 LDRRSQRSEERCVEIP
220 230
>>NP_851827 (OMIM: 606648) interleukin-22 receptor subun (130 aa)
initn: 119 init1: 81 opt: 186 Z-score: 239.5 bits: 51.1 E(85289): 1.3e-06
Smith-Waterman score: 186; 31.0% identity (63.6% similar) in 129 aa overlap (20-141:10-129)
10 20 30 40 50 60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
.:... .. :::...: ... . ..: ::..::.:.:
NP_851 MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPG
10 20 30 40 50
70 80 90 100 110
pF1KB5 PV----NQVYTVQISTKSG-DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAG
. ..:: :: . . .::.: :. : . ::::.: ..:... : .::
NP_851 RALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE-TSDIQEPYYGRV------
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 NVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFL
. :.:: .: . .:.:::. : :
NP_851 RAASAGSYSE--WSMTPRFTPWWERAKGL
110 120 130
>>NP_067081 (OMIM: 605457) interleukin-22 receptor subun (574 aa)
initn: 66 init1: 66 opt: 178 Z-score: 219.9 bits: 49.6 E(85289): 1.7e-05
Smith-Waterman score: 178; 22.3% identity (51.9% similar) in 260 aa overlap (18-270:2-246)
10 20 30 40 50 60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
:::: . ...:. . . .. ..:.::..:: :.
NP_067 MRTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSG
10 20 30 40
70 80 90 100 110
pF1KB5 PV---NQVYTVQISTKSG-DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGN
: . ::... .: . :: .: : : :.:: : . .. . : ::: . ::
NP_067 PEGTPDTVYSIEYKTYGERDWVAKKGCQRITRKSCNLTVE-TGNLTELYYARVTAVSAG-
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 VESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTF-L
:. . . .:. .:.: : . . .: .... :. : .: .. :
NP_067 -------GRSATKMTDRFSSLQHTTLKPPDVTCISKV-RSIQMIVHPTPTPIRAGDGHRL
110 120 130 140 150
180 190 200 210 220 230
pF1KB5 SLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRK
.:.:.: .::.: : . . . . . . .. . .. ... .: : ..
NP_067 TLEDIF-HDLFYHLELQVNRTYQMHLGGKQREYEFFGLTPDTEFLGTIMICVP--TWAKE
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 STDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLN
: .: : . . . . :: .: . .:: .:
NP_067 S--APYMCRVKTLPDRTWTYSFSGAFLFSMGFLVAVLCYLSYRYVTKPPAPPNSLNVQRV
220 230 240 250 260
pF1KB5 VS
NP_067 LTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQ
270 280 290 300 310 320
>>XP_016866443 (OMIM: 605620) PREDICTED: interleukin-20 (554 aa)
initn: 80 init1: 52 opt: 143 Z-score: 177.1 bits: 41.7 E(85289): 0.004
Smith-Waterman score: 228; 26.1% identity (56.1% similar) in 314 aa overlap (1-294:1-289)
10 20 30 40 50
pF1KB5 METPAWPRV-PRPETAVARTLLLG-WVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWE
:..:. : . : : . :: . : : : .:: : :.:. : :.:..:.:
XP_016 MRAPGRPALRPLPLPPLLLLLLAAPWGRA-VPCVSGGLPKPA--NITFLSINMKNVLQWT
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 P----KPVNQVYTVQISTKSGD--W--KSKCFYTTDTECDLTDEIVKDVKQTYLARVFSY
: . :. .:::: . :. : ::.: . : :::. : ..: .. : :.: .
XP_016 PPEGLQGVKVTYTVQYFIRYGQKKWLNKSECRNINRTYCDLSAE-TSDYEHQYYAKVKAI
60 70 80 90 100 110
120 130 140 150 160
pF1KB5 PAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQ-SFEQVGTKVNVTVEDERTLVRRN
:. : . .: .: :.:::..: : . . .. . .: .:. .. .::
XP_016 -WGTKCSK-------WAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEK---WKRN
120 130 140 150 160
170 180 190 200 210 220
pF1KB5 --NTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLID--VDKGENYCFSVQAVI
. .:...... .: :.. ...:.. .. ::. :. .. . :: :.. .
XP_016 PEDLPVSMQQIYS-NLKYNVSVL-NTKSNRTWSQCVTNHTLVLTWLEPNTLYCVHVESFV
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 PSRTVNRKSTDSPVEC---MGQEKGEFRE--IFYIIGAVVFVVIILVIILAISLHKCRKA
:. :.. : .: . ....::. ::. . : ....: ... :.. :
XP_016 PGPP--RRAQPSEKQCARTLKDQSSEFKAKIIFWYVLPVS-ITVFLFSVMGYSIY--RYI
230 240 250 260 270
290
pF1KB5 GVGQSWKENSPLNVS
:: ::. : :.
XP_016 HVG---KEKHPANLILIYGNEFDKRFFVPAEKIVINFITLNISDDSKISHQDMSLLGKSS
280 290 300 310 320 330
295 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:12:15 2016 done: Fri Nov 4 20:12:16 2016
Total Scan time: 6.580 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]