Result of FASTA (omim) for
pFN21AE6115
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6115, 147 aa
1>>>pF1KE6115 147 - 147 aa - 147 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9797+/-0.000353; mu= 13.1037+/- 0.022
mean_var=62.1356+/-12.591, 0's: 0 Z-trim(114.3): 21 B-trim: 295 in 1/51
Lambda= 0.162706
statistics sampled from 24057 (24078) to 24057 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.282), width: 16
Scan time: 5.150
The best scores are: opt bits E(85289)
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 968 235.4 2.6e-62
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 957 232.8 1.5e-61
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 809 198.0 4.4e-51
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 745 183.0 1.5e-46
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 732 180.0 1.2e-45
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 363 93.3 1.4e-19
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 363 93.3 1.4e-19
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 362 93.1 1.7e-19
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 362 93.1 1.7e-19
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 362 93.1 1.8e-19
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 318 82.8 2.1e-16
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 306 80.0 1.5e-15
NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 249 66.7 2e-11
XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 249 66.7 2.1e-11
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 185 51.6 5.7e-07
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 185 51.6 5.7e-07
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 185 51.6 5.7e-07
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 185 51.6 5.7e-07
XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 165 46.9 1.3e-05
NP_067080 (OMIM: 605304) neuroglobin [Homo sapiens ( 151) 139 40.8 0.001
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 968 init1: 968 opt: 968 Z-score: 1239.7 bits: 235.4 E(85289): 2.6e-62
Smith-Waterman score: 968; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
:::::::::::::::::::::::::::
NP_000 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 957 init1: 957 opt: 957 Z-score: 1225.8 bits: 232.8 E(85289): 1.5e-61
Smith-Waterman score: 957; 98.6% identity (99.3% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
::::::::::::::::.::::::::::
NP_000 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>NP_005321 (OMIM: 142100) hemoglobin subunit epsilon [H (147 aa)
initn: 809 init1: 809 opt: 809 Z-score: 1038.0 bits: 198.0 E(85289): 4.4e-51
Smith-Waterman score: 809; 79.6% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
: ::: :.::..::::.:.:::.::::.::::::::::::::::::::::: :::.::::
NP_005 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
:::::::::::.::: :..:.:: .::.::::::::::::::::::::::.: .:: :::
NP_005 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
:::::::::.:::.:.::: ::. .::
NP_005 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>NP_000509 (OMIM: 140700,141749,141900,603902,603903,60 (147 aa)
initn: 745 init1: 745 opt: 745 Z-score: 956.8 bits: 183.0 E(85289): 1.5e-46
Smith-Waterman score: 745; 72.8% identity (92.5% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
: :.: :.:...:.:::::::...:::.:::::::::::::::.:::.::. .:.:::::
NP_000 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::: ...:. :::.:::::: ::::::::::::::::.::::::: ::: :::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
::::: :::..::.:..::.::. .::
NP_000 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>NP_000510 (OMIM: 142000) hemoglobin subunit delta [Hom (147 aa)
initn: 732 init1: 732 opt: 732 Z-score: 940.3 bits: 180.0 E(85289): 1.2e-45
Smith-Waterman score: 732; 71.4% identity (93.2% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
: :.: :.:.....:::::::. .:::.:::::::::::::::.:::.::: .:.:::::
NP_000 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::: ...:. :::.:::::.:::::::::::::::::.::::::: ::: .::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
:::::..::..::.:..::.::. .::
NP_000 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>NP_000508 (OMIM: 140700,141850,604131,613978) hemoglob (142 aa)
initn: 311 init1: 274 opt: 363 Z-score: 472.4 bits: 93.3 E(85289): 1.4e-19
Smith-Waterman score: 363; 41.4% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.. ::... . ::::... . :.:.: :... .: :. .: : .:: .::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSHGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
.::.::::: .: .:. :.::. .... ::.:: ::.::: :::::.. :...:: :
NP_000 -QVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
. :::: :.:: .:....:...:.:.:
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 311 init1: 274 opt: 363 Z-score: 472.4 bits: 93.3 E(85289): 1.4e-19
Smith-Waterman score: 363; 41.4% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.. ::... . ::::... . :.:.: :... .: :. .: : .:: .::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSHGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
.::.::::: .: .:. :.::. .... ::.:: ::.::: :::::.. :...:: :
NP_000 -QVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
. :::: :.:: .:....:...:.:.:
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 324 init1: 272 opt: 362 Z-score: 471.2 bits: 93.1 E(85289): 1.7e-19
Smith-Waterman score: 362; 40.7% identity (78.6% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE-DA-GGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.:. ... :.:.:.:.... :. : ::: ::.. .: :. .: : .: .::
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLHPGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
...:::.::....:::.: .::. :....::::: :.::: :::::.. :...:: .
XP_005 -QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
: .:: :..:.:.:....:.:.:. .:
XP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 324 init1: 272 opt: 362 Z-score: 471.2 bits: 93.1 E(85289): 1.7e-19
Smith-Waterman score: 362; 40.7% identity (78.6% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE-DA-GGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.:. ... :.:.:.:.... :. : ::: ::.. .: :. .: : .: .::
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLHPGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
...:::.::....:::.: .::. :....::::: :.::: :::::.. :...:: .
NP_005 -QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
: .:: :..:.:.:....:.:.:. .:
NP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 324 init1: 272 opt: 362 Z-score: 470.7 bits: 93.1 E(85289): 1.8e-19
Smith-Waterman score: 362; 40.7% identity (78.6% similar) in 145 aa overlap (4-146:15-153)
10 20 30 40
pF1KE6 MGHFTEEDKATITSLWGKVNVE-DA-GGETLGRLLVVYPWTQRFFDSFG
.:. ... :.:.:.:.... :. : ::: ::.. .: :. .: :
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 NLSSASAIMGNPKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLL
.: .:: ...:::.::....:::.: .::. :....::::: :.::: :::::
XP_005 DLHPGSA-----QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLL
60 70 80 90 100 110
110 120 130 140
pF1KE6 GNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH
.. :...:: .: .:: :..:.:.:....:.:.:. .:
XP_005 SHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140 150
147 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:34:39 2016 done: Tue Nov 8 09:34:40 2016
Total Scan time: 5.150 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]