Result of FASTA (ccds) for
pFN21AE6115
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6115, 147 aa
1>>>pF1KE6115 147 - 147 aa - 147 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3495+/-0.00079; mu= 10.6884+/- 0.047
mean_var=58.3530+/-11.822, 0's: 0 Z-trim(107.2): 15 B-trim: 62 in 1/49
Lambda= 0.167897
statistics sampled from 9436 (9450) to 9436 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.29), width: 16
Scan time: 1.360
The best scores are: opt bits E(32554)
CCDS7754.1 HBG1 gene_id:3047|Hs108|chr11 ( 147) 968 242.4 7.4e-65
CCDS7755.1 HBG2 gene_id:3048|Hs108|chr11 ( 147) 957 239.8 4.7e-64
CCDS7756.1 HBE1 gene_id:3046|Hs108|chr11 ( 147) 809 203.9 2.9e-53
CCDS7753.1 HBB gene_id:3043|Hs108|chr11 ( 147) 745 188.4 1.3e-48
CCDS31376.1 HBD gene_id:3045|Hs108|chr11 ( 147) 732 185.3 1.2e-47
CCDS10398.1 HBA2 gene_id:3040|Hs108|chr16 ( 142) 363 95.9 9.3e-21
CCDS10399.1 HBA1 gene_id:3039|Hs108|chr16 ( 142) 363 95.9 9.3e-21
CCDS10397.1 HBZ gene_id:3050|Hs108|chr16 ( 142) 362 95.6 1.1e-20
CCDS10400.1 HBQ1 gene_id:3049|Hs108|chr16 ( 142) 318 85.0 1.8e-17
CCDS32347.1 HBM gene_id:3042|Hs108|chr16 ( 141) 306 82.1 1.3e-16
CCDS11746.1 CYGB gene_id:114757|Hs108|chr17 ( 190) 249 68.3 2.5e-12
>>CCDS7754.1 HBG1 gene_id:3047|Hs108|chr11 (147 aa)
initn: 968 init1: 968 opt: 968 Z-score: 1277.9 bits: 242.4 E(32554): 7.4e-65
Smith-Waterman score: 968; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
:::::::::::::::::::::::::::
CCDS77 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>CCDS7755.1 HBG2 gene_id:3048|Hs108|chr11 (147 aa)
initn: 957 init1: 957 opt: 957 Z-score: 1263.5 bits: 239.8 E(32554): 4.7e-64
Smith-Waterman score: 957; 98.6% identity (99.3% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
::::::::::::::::.::::::::::
CCDS77 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>CCDS7756.1 HBE1 gene_id:3046|Hs108|chr11 (147 aa)
initn: 809 init1: 809 opt: 809 Z-score: 1069.8 bits: 203.9 E(32554): 2.9e-53
Smith-Waterman score: 809; 79.6% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
: ::: :.::..::::.:.:::.::::.::::::::::::::::::::::: :::.::::
CCDS77 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
:::::::::::.::: :..:.:: .::.::::::::::::::::::::::.: .:: :::
CCDS77 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
:::::::::.:::.:.::: ::. .::
CCDS77 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>CCDS7753.1 HBB gene_id:3043|Hs108|chr11 (147 aa)
initn: 745 init1: 745 opt: 745 Z-score: 986.0 bits: 188.4 E(32554): 1.3e-48
Smith-Waterman score: 745; 72.8% identity (92.5% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
: :.: :.:...:.:::::::...:::.:::::::::::::::.:::.::. .:.:::::
CCDS77 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::: ...:. :::.:::::: ::::::::::::::::.::::::: ::: :::
CCDS77 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
::::: :::..::.:..::.::. .::
CCDS77 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>CCDS31376.1 HBD gene_id:3045|Hs108|chr11 (147 aa)
initn: 732 init1: 732 opt: 732 Z-score: 969.0 bits: 185.3 E(32554): 1.2e-47
Smith-Waterman score: 732; 71.4% identity (93.2% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
: :.: :.:.....:::::::. .:::.:::::::::::::::.:::.::: .:.:::::
CCDS31 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
::::::::: ...:. :::.:::::.:::::::::::::::::.::::::: ::: .::
CCDS31 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPEVQASWQKMVTAVASALSSRYH
:::::..::..::.:..::.::. .::
CCDS31 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>CCDS10398.1 HBA2 gene_id:3040|Hs108|chr16 (142 aa)
initn: 311 init1: 274 opt: 363 Z-score: 486.1 bits: 95.9 E(32554): 9.3e-21
Smith-Waterman score: 363; 41.4% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.. ::... . ::::... . :.:.: :... .: :. .: : .:: .::
CCDS10 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSHGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
.::.::::: .: .:. :.::. .... ::.:: ::.::: :::::.. :...:: :
CCDS10 -QVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
. :::: :.:: .:....:...:.:.:
CCDS10 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>CCDS10399.1 HBA1 gene_id:3039|Hs108|chr16 (142 aa)
initn: 311 init1: 274 opt: 363 Z-score: 486.1 bits: 95.9 E(32554): 9.3e-21
Smith-Waterman score: 363; 41.4% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.. ::... . ::::... . :.:.: :... .: :. .: : .:: .::
CCDS10 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSHGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
.::.::::: .: .:. :.::. .... ::.:: ::.::: :::::.. :...:: :
CCDS10 -QVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
. :::: :.:: .:....:...:.:.:
CCDS10 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>CCDS10397.1 HBZ gene_id:3050|Hs108|chr16 (142 aa)
initn: 324 init1: 272 opt: 362 Z-score: 484.8 bits: 95.6 E(32554): 1.1e-20
Smith-Waterman score: 362; 40.7% identity (78.6% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVE-DA-GGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.:. ... :.:.:.:.... :. : ::: ::.. .: :. .: : .: .::
CCDS10 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLHPGSA----
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
...:::.::....:::.: .::. :....::::: :.::: :::::.. :...:: .
CCDS10 -QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
: .:: :..:.:.:....:.:.:. .:
CCDS10 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>CCDS10400.1 HBQ1 gene_id:3049|Hs108|chr16 (142 aa)
initn: 275 init1: 239 opt: 318 Z-score: 427.2 bits: 85.0 E(32554): 1.8e-17
Smith-Waterman score: 318; 40.0% identity (70.3% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKV--NVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.. ::.: . .:: :. :: :.: : ....: :. .: : .:: :.
CCDS10 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYF-SHLDLSP-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
.:.:::.:: .:. :...:::: ... ::.:: .:.::: .:.:::. :...:: :
CCDS10 SQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
. .:.: .::: .:... : ::: :.:
CCDS10 YPGDFSPALQASLDKFLSHVISALVSEYR
120 130 140
>>CCDS32347.1 HBM gene_id:3042|Hs108|chr16 (141 aa)
initn: 284 init1: 242 opt: 306 Z-score: 411.6 bits: 82.1 E(32554): 1.3e-16
Smith-Waterman score: 306; 34.5% identity (73.1% similar) in 145 aa overlap (4-146:2-140)
10 20 30 40 50
pF1KE6 MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
.. ...: :...: . ..: :.: : ::..::: :. .: .. ..:. ..
CCDS32 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLL--
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
.::...:...: :..:.:.:..... :..:: :.::: :: :: . . .::: :
CCDS32 ----SHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPEVQASWQKMVTAVASALSSRYH
. ::: ..::.:.:..:.:: .:. .:
CCDS32 LQDEFTVQMQAAWDKFLTGVAVVLTEKYR
120 130 140
147 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:34:39 2016 done: Tue Nov 8 09:34:39 2016
Total Scan time: 1.360 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]