Result of FASTA (omim) for
pFN21AB6642
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6642, 443 aa
1>>>pF1KB6642 443 - 443 aa - 443 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0127+/-0.000362; mu= 7.2144+/- 0.023
mean_var=230.6623+/-46.688, 0's: 0 Z-trim(122.0): 434 B-trim: 41 in 1/55
Lambda= 0.084447
statistics sampled from 39050 (39561) to 39050 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.464), width: 16
Scan time: 8.970
The best scores are: opt bits E(85289)
NP_058634 (OMIM: 604633,614437) EGF-containing fib ( 443) 3284 412.8 9.1e-115
NP_001034438 (OMIM: 126600,601548) EGF-containing ( 493) 1551 201.7 3.6e-51
NP_001034437 (OMIM: 126600,601548) EGF-containing ( 493) 1551 201.7 3.6e-51
NP_006320 (OMIM: 219100,604580,608895,614434) fibu ( 448) 1540 200.3 8.4e-51
XP_005267324 (OMIM: 219100,604580,608895,614434) P ( 465) 1540 200.3 8.6e-51
XP_016876418 (OMIM: 219100,604580,608895,614434) P ( 392) 1525 198.4 2.7e-50
XP_011534659 (OMIM: 219100,604580,608895,614434) P ( 464) 1347 176.8 1e-43
XP_011534658 (OMIM: 219100,604580,608895,614434) P ( 481) 1347 176.8 1.1e-43
XP_011534660 (OMIM: 219100,604580,608895,614434) P ( 408) 1332 174.9 3.4e-43
XP_016859075 (OMIM: 126600,601548) PREDICTED: EGF- ( 413) 1069 142.9 1.5e-33
XP_005264262 (OMIM: 126600,601548) PREDICTED: EGF- ( 543) 1069 143.0 1.8e-33
NP_001157738 (OMIM: 601216,602090,613097) latent-t (1139) 664 94.0 2.1e-18
NP_066548 (OMIM: 601216,602090,613097) latent-tran (1256) 664 94.1 2.3e-18
XP_011543335 (OMIM: 601216,602090,613097) PREDICTE (1265) 664 94.1 2.3e-18
NP_001123616 (OMIM: 601216,602090,613097) latent-t (1303) 664 94.1 2.3e-18
XP_011543334 (OMIM: 601216,602090,613097) PREDICTE (1312) 664 94.1 2.3e-18
XP_011525684 (OMIM: 604710,613177) PREDICTED: late (1554) 638 91.0 2.4e-17
XP_016857926 (OMIM: 603075,608548) PREDICTED: hemi (4976) 620 89.4 2.4e-16
NP_114141 (OMIM: 603075,608548) hemicentin-1 precu (5635) 620 89.4 2.6e-16
XP_016859599 (OMIM: 150390) PREDICTED: latent-tran (1639) 608 87.4 3.1e-16
XP_016859597 (OMIM: 150390) PREDICTED: latent-tran (1681) 608 87.4 3.1e-16
XP_011531158 (OMIM: 150390) PREDICTED: latent-tran (1682) 608 87.4 3.1e-16
XP_011508340 (OMIM: 603075,608548) PREDICTED: hemi (5518) 615 88.8 3.9e-16
XP_011525689 (OMIM: 604710,613177) PREDICTED: late (1421) 596 85.9 7.7e-16
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436) 596 85.9 7.7e-16
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438) 596 85.9 7.8e-16
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478) 596 85.9 7.9e-16
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480) 596 85.9 7.9e-16
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522) 596 85.9 8.1e-16
XP_016882842 (OMIM: 604710,613177) PREDICTED: late (1549) 596 85.9 8.2e-16
NP_001036010 (OMIM: 604710,613177) latent-transfor (1557) 596 85.9 8.2e-16
NP_003564 (OMIM: 604710,613177) latent-transformin (1587) 596 85.9 8.3e-16
XP_016882841 (OMIM: 604710,613177) PREDICTED: late (1591) 596 85.9 8.3e-16
XP_011525682 (OMIM: 604710,613177) PREDICTED: late (1593) 596 85.9 8.3e-16
XP_011525683 (OMIM: 604710,613177) PREDICTED: late (1593) 596 85.9 8.3e-16
XP_011525681 (OMIM: 604710,613177) PREDICTED: late (1595) 596 85.9 8.3e-16
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611) 596 85.9 8.4e-16
NP_001036009 (OMIM: 604710,613177) latent-transfor (1624) 596 85.9 8.4e-16
XP_011525679 (OMIM: 604710,613177) PREDICTED: late (1635) 596 85.9 8.5e-16
XP_011525678 (OMIM: 604710,613177) PREDICTED: late (1662) 596 85.9 8.6e-16
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 594 85.9 1.5e-15
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861) 572 83.3 9.4e-15
XP_011539190 (OMIM: 604266) PREDICTED: multiple ep (1364) 566 82.2 9.4e-15
NP_001990 (OMIM: 121050,612570,616118) fibrillin-2 (2912) 572 83.3 9.5e-15
NP_001400 (OMIM: 604266) multiple epidermal growth (1541) 566 82.2 1e-14
XP_016856022 (OMIM: 604266) PREDICTED: multiple ep (1559) 566 82.2 1e-14
XP_011539188 (OMIM: 604266) PREDICTED: multiple ep (1560) 566 82.2 1e-14
XP_011539187 (OMIM: 604266) PREDICTED: multiple ep (1603) 566 82.3 1.1e-14
NP_006478 (OMIM: 135820,608180) fibulin-1 isoform ( 566) 546 79.3 2.8e-14
NP_006476 (OMIM: 135820,608180) fibulin-1 isoform ( 601) 546 79.4 2.9e-14
>>NP_058634 (OMIM: 604633,614437) EGF-containing fibulin (443 aa)
initn: 3284 init1: 3284 opt: 3284 Z-score: 2181.4 bits: 412.8 E(85289): 9.1e-115
Smith-Waterman score: 3284; 99.8% identity (100.0% similar) in 443 aa overlap (1-443:1-443)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 PGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTC
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_058 CSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 VNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 VNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 FQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 FQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTM
370 380 390 400 410 420
430 440
pF1KB6 NSLMSYRASSVLRLTVFVGAYTF
:::::::::::::::::::::::
NP_058 NSLMSYRASSVLRLTVFVGAYTF
430 440
>>NP_001034438 (OMIM: 126600,601548) EGF-containing fibu (493 aa)
initn: 1846 init1: 693 opt: 1551 Z-score: 1039.8 bits: 201.7 E(85289): 3.6e-51
Smith-Waterman score: 1774; 50.4% identity (70.8% similar) in 476 aa overlap (29-443:19-493)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
:.:: .::.::::::::: :.:.:..::
NP_001 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDI
10 20 30 40 50
70 80 90
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVIND------------------------------
.:.:::: :::.::::::::::..: .: .
NP_001 VPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATS
60 70 80 90 100 110
100 110 120
pF1KB6 --LHG----------EGPP------------PPVPPAQHP-NP-----CPPGYEPDDQDS
: : :: :. : . : :: : ::: ....
NP_001 GVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV
120 130 140 150 160 170
130 140 150 160 170
pF1KB6 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR-YCQHRCVN
: :.:::. . :.:: .: : :: ::. : :: ::.: : .::::::: ::..::::
NP_001 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVN
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB6 LPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGF
:::: ::: :::::. :: .:::.:::: . : :.:.: :.:.:.:.::::: : .
NP_001 TPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRL
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB6 SCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQT
.: ::::: :::::::.::::::.::: ::::::.. .: ::::.:::. ...: : .
NP_001 NCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECET-TNECREDEM
300 310 320 330 340
300 310 320 330 340 350
pF1KB6 CVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPAD
: :.:::.:: : : .::: . ::::.::.:: .::: :.:::..::.: :.::::.:
NP_001 CWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSD
350 360 370 380 390 400
360 370 380 390 400 410
pF1KB6 VFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVT
.::::::..: .. :.:.:..:: .:.::.:: . :::::::.. ..::::...::::.:
NP_001 IFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLT
410 420 430 440 450 460
420 430 440
pF1KB6 MNSLMSYRASSVLRLTVFVGAYTF
..:. ..:.:::::::..:: ..:
NP_001 VSSIGTFRTSSVLRLTIIVGPFSF
470 480 490
>>NP_001034437 (OMIM: 126600,601548) EGF-containing fibu (493 aa)
initn: 1846 init1: 693 opt: 1551 Z-score: 1039.8 bits: 201.7 E(85289): 3.6e-51
Smith-Waterman score: 1774; 50.4% identity (70.8% similar) in 476 aa overlap (29-443:19-493)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
:.:: .::.::::::::: :.:.:..::
NP_001 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDI
10 20 30 40 50
70 80 90
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVIND------------------------------
.:.:::: :::.::::::::::..: .: .
NP_001 VPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATS
60 70 80 90 100 110
100 110 120
pF1KB6 --LHG----------EGPP------------PPVPPAQHP-NP-----CPPGYEPDDQDS
: : :: :. : . : :: : ::: ....
NP_001 GVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV
120 130 140 150 160 170
130 140 150 160 170
pF1KB6 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR-YCQHRCVN
: :.:::. . :.:: .: : :: ::. : :: ::.: : .::::::: ::..::::
NP_001 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVN
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB6 LPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGF
:::: ::: :::::. :: .:::.:::: . : :.:.: :.:.:.:.::::: : .
NP_001 TPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRL
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB6 SCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQT
.: ::::: :::::::.::::::.::: ::::::.. .: ::::.:::. ...: : .
NP_001 NCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECET-TNECREDEM
300 310 320 330 340
300 310 320 330 340 350
pF1KB6 CVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPAD
: :.:::.:: : : .::: . ::::.::.:: .::: :.:::..::.: :.::::.:
NP_001 CWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSD
350 360 370 380 390 400
360 370 380 390 400 410
pF1KB6 VFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVT
.::::::..: .. :.:.:..:: .:.::.:: . :::::::.. ..::::...::::.:
NP_001 IFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLT
410 420 430 440 450 460
420 430 440
pF1KB6 MNSLMSYRASSVLRLTVFVGAYTF
..:. ..:.:::::::..:: ..:
NP_001 VSSIGTFRTSSVLRLTIIVGPFSF
470 480 490
>>NP_006320 (OMIM: 219100,604580,608895,614434) fibulin- (448 aa)
initn: 1703 init1: 791 opt: 1540 Z-score: 1033.0 bits: 200.3 E(85289): 8.4e-51
Smith-Waterman score: 1734; 50.1% identity (72.8% similar) in 453 aa overlap (8-443:1-448)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
.:: . .. .: : :: ... ..::.:.. : .: .: :..:: :
NP_006 MPGIKRILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSGQCLDIDECRT
10 20 30 40
70 80 90 100
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE-------GP-PPPVPPAQHPN-P---
:::::.:.: :.:. :::::.::. : ... :: : .:: . :: :
NP_006 IPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTIS
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 ----CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVD
: ::. :....:::::::: :.: :.: : : :.: :.: ::: . .:.:
NP_006 RPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLD
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 IDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTF
:::::: :::. :.:.:::. : :.::: :. ..::: ::::: :: : : :.::.:
NP_006 IDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 LCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLA-TRLCQD
.::: ::::..:: :::.::::.: .:::..:::.:: . : :: :: :: .: :::
NP_006 ICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 IDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSI
:.::: : :. ::: :..::..:.: :: :::...:.:::.::: :: ::.:: .:
NP_006 INECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTI
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB6 VHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLAR
..: : ..: ::::::.::.:::. ::::: :::..:: .::.:: . .:: ::..:
NP_006 LYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTR
350 360 370 380 390 400
410 420 430 440
pF1KB6 PVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
:. :::: :::::.:.:.....:.:::.:: ..:. : :
NP_006 PIKGPREIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
410 420 430 440
>>XP_005267324 (OMIM: 219100,604580,608895,614434) PREDI (465 aa)
initn: 1703 init1: 791 opt: 1540 Z-score: 1032.8 bits: 200.3 E(85289): 8.6e-51
Smith-Waterman score: 1725; 50.2% identity (73.2% similar) in 448 aa overlap (13-443:23-465)
10 20 30 40 50
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQ
.. .. .: : :: ... ..::.:.. : .:
XP_005 MFVWDSHRSFKPMRSGNCRQRYMILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSG
10 20 30 40 50
60 70 80 90 100
pF1KB6 HCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE-------GP-PPPVPP
.: :..:: ::::::.:.: :.:. :::::.::. : ... :: : .::
XP_005 QCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPP
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 AQHPN-P-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDG
. :: : : ::. :....:::::::: :.: :.: : : :.: :.: ::
XP_005 LSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE
: . .:.::::::: :::. :.:.:::. : :.::: :. ..::: ::::: ::
XP_005 YWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ
: : :.::.:.::: ::::..:: :::.::::.: .:::..:::.:: . : :: ::
XP_005 QTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 LLA-TRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASN
:: .: ::::.::: : :. ::: :..::..:.: :: :::...:.:::.::: :
XP_005 LLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAEN
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 PLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQIN
: ::.:: .:..: : ..: ::::::.::.:::. ::::: :::..:: .::.:: .
XP_005 PGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTG
360 370 380 390 400 410
400 410 420 430 440
pF1KB6 NVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
.:: ::..::. :::: :::::.:.:.....:.:::.:: ..:. : :
XP_005 PISATLVMTRPIKGPREIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
420 430 440 450 460
>>XP_016876418 (OMIM: 219100,604580,608895,614434) PREDI (392 aa)
initn: 1485 init1: 791 opt: 1525 Z-score: 1023.8 bits: 198.4 E(85289): 2.7e-50
Smith-Waterman score: 1581; 52.3% identity (73.7% similar) in 392 aa overlap (69-443:1-392)
40 50 60 70 80 90
pF1KB6 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE----
: :.:. :::::.::. : ...
XP_016 MMCVNQNGGYLCIPRTNPVYRGPYSNPYST
10 20 30
100 110 120 130 140
pF1KB6 ---GP-PPPVPPAQHPN-P-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN
:: : .:: . :: : : ::. :....:::::::: :.: :.: : :
XP_016 PYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICIN
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 LPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCV
:.: :.: ::: . .:.::::::: :::. :.:.:::. : :.::: :. ..:::
XP_016 TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQ
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP
::::: :: : : :.::.:.::: ::::..:: :::.::::.: .:::..:::.:
XP_016 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 GRFSCHCPQGYQLLA-TRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQ
: . : :: :: :: .: ::::.::: : :. ::: :..::..:.: :: :::..
XP_016 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 VSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAG
.:.:::.::: :: ::.:: .:..: : ..: ::::::.::.:::. ::::: :::..:
XP_016 ISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSG
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB6 NSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAY
: .::.:: . .:: ::..::. :::: :::::.:.:.....:.:::.:: ..:. :
XP_016 NEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMITVNTVINFRGSSVIRLRIYVSQY
340 350 360 370 380 390
pF1KB6 TF
:
XP_016 PF
>>XP_011534659 (OMIM: 219100,604580,608895,614434) PREDI (464 aa)
initn: 1507 init1: 791 opt: 1347 Z-score: 905.8 bits: 176.8 E(85289): 1e-43
Smith-Waterman score: 1541; 49.4% identity (71.5% similar) in 407 aa overlap (8-397:1-402)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
.:: . .. .: : :: ... ..::.:.. : .: .: :..:: :
XP_011 MPGIKRILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSGQCLDIDECRT
10 20 30 40
70 80 90 100
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE-------GP-PPPVPPAQHPN-P---
:::::.:.: :.:. :::::.::. : ... :: : .:: . :: :
XP_011 IPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTIS
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 ----CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVD
: ::. :....:::::::: :.: :.: : : :.: :.: ::: . .:.:
XP_011 RPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLD
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 IDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTF
:::::: :::. :.:.:::. : :.::: :. ..::: ::::: :: : : :.::.:
XP_011 IDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 LCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLA-TRLCQD
.::: ::::..:: :::.::::.: .:::..:::.:: . : :: :: :: .: :::
XP_011 ICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 IDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSI
:.::: : :. ::: :..::..:.: :: :::...:.:::.::: :: ::.:: .:
XP_011 INECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTI
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB6 VHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLAR
..: : ..: ::::::.::.:::. ::::: :::..:: .::.:. ...:
XP_011 LYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRRAFSTTAYEASSQ
350 360 370 380 390 400
410 420 430 440
pF1KB6 PVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
XP_011 ALSVEKQTGCGLCPGGTHTHLSGEGENNLANTTQSGDSQVKSRPMGCKRAPSVPPW
410 420 430 440 450 460
>>XP_011534658 (OMIM: 219100,604580,608895,614434) PREDI (481 aa)
initn: 1507 init1: 791 opt: 1347 Z-score: 905.6 bits: 176.8 E(85289): 1.1e-43
Smith-Waterman score: 1532; 49.5% identity (71.9% similar) in 402 aa overlap (13-397:23-419)
10 20 30 40 50
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQ
.. .. .: : :: ... ..::.:.. : .:
XP_011 MFVWDSHRSFKPMRSGNCRQRYMILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSG
10 20 30 40 50
60 70 80 90 100
pF1KB6 HCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE-------GP-PPPVPP
.: :..:: ::::::.:.: :.:. :::::.::. : ... :: : .::
XP_011 QCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPP
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 AQHPN-P-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDG
. :: : : ::. :....:::::::: :.: :.: : : :.: :.: ::
XP_011 LSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE
: . .:.::::::: :::. :.:.:::. : :.::: :. ..::: ::::: ::
XP_011 YWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ
: : :.::.:.::: ::::..:: :::.::::.: .:::..:::.:: . : :: ::
XP_011 QTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 LLA-TRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASN
:: .: ::::.::: : :. ::: :..::..:.: :: :::...:.:::.::: :
XP_011 LLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAEN
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 PLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQIN
: ::.:: .:..: : ..: ::::::.::.:::. ::::: :::..:: .::.:.
XP_011 PGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRRAF
360 370 380 390 400 410
400 410 420 430 440
pF1KB6 NVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
...:
XP_011 STTAYEASSQALSVEKQTGCGLCPGGTHTHLSGEGENNLANTTQSGDSQVKSRPMGCKRA
420 430 440 450 460 470
>>XP_011534660 (OMIM: 219100,604580,608895,614434) PREDI (408 aa)
initn: 1289 init1: 791 opt: 1332 Z-score: 896.6 bits: 174.9 E(85289): 3.4e-43
Smith-Waterman score: 1388; 51.7% identity (72.3% similar) in 346 aa overlap (69-397:1-346)
40 50 60 70 80 90
pF1KB6 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE----
: :.:. :::::.::. : ...
XP_011 MMCVNQNGGYLCIPRTNPVYRGPYSNPYST
10 20 30
100 110 120 130 140
pF1KB6 ---GP-PPPVPPAQHPN-P-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN
:: : .:: . :: : : ::. :....:::::::: :.: :.: : :
XP_011 PYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICIN
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 LPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCV
:.: :.: ::: . .:.::::::: :::. :.:.:::. : :.::: :. ..:::
XP_011 TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQ
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP
::::: :: : : :.::.:.::: ::::..:: :::.::::.: .:::..:::.:
XP_011 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 GRFSCHCPQGYQLLA-TRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQ
: . : :: :: :: .: ::::.::: : :. ::: :..::..:.: :: :::..
XP_011 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 VSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAG
.:.:::.::: :: ::.:: .:..: : ..: ::::::.::.:::. ::::: :::..:
XP_011 ISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSG
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB6 NSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAY
: .::.:. ...:
XP_011 NEGREFYMRRAFSTTAYEASSQALSVEKQTGCGLCPGGTHTHLSGEGENNLANTTQSGDS
340 350 360 370 380 390
>>XP_016859075 (OMIM: 126600,601548) PREDICTED: EGF-cont (413 aa)
initn: 1570 init1: 602 opt: 1069 Z-score: 723.3 bits: 142.9 E(85289): 1.5e-33
Smith-Waterman score: 1376; 45.9% identity (68.8% similar) in 442 aa overlap (13-443:1-413)
10 20 30 40 50
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSA--SPQDSEEPDSYTECTDGYEWDPDSQHCRDVNEC
.: ::.: .: : . ::.:: .::.::::::::: :.:.:..::
XP_016 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDEC
10 20 30 40
60 70 80 90 100 110
pF1KB6 LTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQ
.:.:::: :::.::::::::::..: .: ...: : . ::. . :
XP_016 DIVPDACKGGMKCVNHYGGYLCLPKTAQII--VNNEQPQQETQPAEGTSGATTGV-----
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCV
: ..: :::. . . ::: .. : . .:
XP_016 -----VAASSMATSGV--------LPGGGFVASAAAV--AGPE---MQTGRNNFVIRRNP
110 120 130 140
180 190 200 210 220
pF1KB6 NLPG------SFRCQCEPGFQLGPNNRSCVDVNECDMGAP-C--EQRCFNSYGTFLCRCH
: : : :: :.. . .: : :..:: :. : .: :.: :.: :.:
XP_016 ADPQRIPSNPSHRIQCAAGYEQSEHN-VCQDIDECTAGTHNCRADQVCINLRGSFACQCP
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB6 QGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECES
::. . : .: ::::: :::::::.::::::.::: ::::::.. .: ::::.:::.
XP_016 PGYQ--KRGEQCVDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECET
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB6 GAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMT
...: : . : :.:::.:: : : .::: . ::::.::.:: .::: :.:::..::.
XP_016 -TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMS
270 280 290 300 310
350 360 370 380 390 400
pF1KB6 ITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPR
: :.::::.:.::::::..: .. :.:.:..:: .:.::.:: . :::::::.. ..:::
XP_016 IRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPR
320 330 340 350 360 370
410 420 430 440
pF1KB6 EYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
:...::::.:..:. ..:.:::::::..:: ..:
XP_016 EHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
380 390 400 410
443 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:39:09 2016 done: Sat Nov 5 11:39:10 2016
Total Scan time: 8.970 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]