Result of FASTA (ccds) for
pFN21AB6642
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6642, 443 aa
1>>>pF1KB6642 443 - 443 aa - 443 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3026+/-0.000932; mu= 11.7394+/- 0.057
mean_var=220.6991+/-43.307, 0's: 0 Z-trim(114.6): 173 B-trim: 68 in 1/53
Lambda= 0.086332
statistics sampled from 14930 (15121) to 14930 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.464), width: 16
Scan time: 3.390
The best scores are: opt bits E(32554)
CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11 ( 443) 3284 421.5 8.1e-118
CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2 ( 493) 1551 205.8 8.2e-53
CCDS9898.1 FBLN5 gene_id:10516|Hs108|chr14 ( 448) 1540 204.3 2e-52
CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256) 664 95.8 2.7e-19
CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303) 664 95.8 2.7e-19
CCDS30956.1 HMCN1 gene_id:83872|Hs108|chr1 (5635) 620 91.1 3.1e-17
CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557) 596 87.4 1.1e-16
CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19 (1587) 596 87.4 1.1e-16
CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19 (1624) 596 87.4 1.1e-16
CCDS32232.1 FBN1 gene_id:2200|Hs108|chr15 (2871) 594 87.5 1.9e-16
CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5 (2912) 572 84.8 1.3e-15
CCDS41237.1 MEGF6 gene_id:1953|Hs108|chr1 (1541) 566 83.7 1.4e-15
CCDS43028.1 FBLN1 gene_id:2192|Hs108|chr22 ( 566) 546 80.7 4.3e-15
CCDS14068.1 FBLN1 gene_id:2192|Hs108|chr22 ( 601) 546 80.7 4.5e-15
CCDS14069.1 FBLN1 gene_id:2192|Hs108|chr22 ( 683) 546 80.8 4.8e-15
CCDS14067.1 FBLN1 gene_id:2192|Hs108|chr22 ( 703) 546 80.8 4.9e-15
CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2 (1342) 539 80.2 1.4e-14
CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2 (1353) 539 80.2 1.4e-14
CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2 (1395) 539 80.3 1.4e-14
CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2 (1721) 539 80.4 1.6e-14
CCDS55265.1 MATN2 gene_id:4147|Hs108|chr8 ( 937) 522 77.9 4.7e-14
CCDS55264.1 MATN2 gene_id:4147|Hs108|chr8 ( 956) 522 77.9 4.7e-14
CCDS12196.1 FBN3 gene_id:84467|Hs108|chr19 (2809) 515 77.6 1.7e-13
CCDS13149.1 CD93 gene_id:22918|Hs108|chr20 ( 652) 501 75.1 2.3e-13
CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3 (1184) 498 75.1 4.3e-13
CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3 (1231) 498 75.1 4.4e-13
CCDS14048.1 SCUBE1 gene_id:80274|Hs108|chr22 ( 988) 491 74.1 7e-13
CCDS7797.2 SCUBE2 gene_id:57758|Hs108|chr11 ( 971) 484 73.2 1.3e-12
CCDS53599.1 SCUBE2 gene_id:57758|Hs108|chr11 ( 807) 465 70.8 5.8e-12
CCDS14155.1 EGFL6 gene_id:25975|Hs108|chrX ( 553) 462 70.2 6e-12
CCDS55370.1 EGFL6 gene_id:25975|Hs108|chrX ( 554) 462 70.2 6e-12
CCDS81553.1 SCUBE2 gene_id:57758|Hs108|chr11 ( 999) 466 71.0 6.1e-12
CCDS12326.1 NOTCH3 gene_id:4854|Hs108|chr19 (2321) 444 68.7 7e-11
>>CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11 (443 aa)
initn: 3284 init1: 3284 opt: 3284 Z-score: 2228.7 bits: 421.5 E(32554): 8.1e-118
Smith-Waterman score: 3284; 99.8% identity (100.0% similar) in 443 aa overlap (1-443:1-443)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTC
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
CCDS81 CSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 VNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 FQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTM
370 380 390 400 410 420
430 440
pF1KB6 NSLMSYRASSVLRLTVFVGAYTF
:::::::::::::::::::::::
CCDS81 NSLMSYRASSVLRLTVFVGAYTF
430 440
>>CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2 (493 aa)
initn: 1846 init1: 693 opt: 1551 Z-score: 1061.6 bits: 205.8 E(32554): 8.2e-53
Smith-Waterman score: 1774; 50.4% identity (70.8% similar) in 476 aa overlap (29-443:19-493)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
:.:: .::.::::::::: :.:.:..::
CCDS18 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDI
10 20 30 40 50
70 80 90
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVIND------------------------------
.:.:::: :::.::::::::::..: .: .
CCDS18 VPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATS
60 70 80 90 100 110
100 110 120
pF1KB6 --LHG----------EGPP------------PPVPPAQHP-NP-----CPPGYEPDDQDS
: : :: :. : . : :: : ::: ....
CCDS18 GVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV
120 130 140 150 160 170
130 140 150 160 170
pF1KB6 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR-YCQHRCVN
: :.:::. . :.:: .: : :: ::. : :: ::.: : .::::::: ::..::::
CCDS18 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVN
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB6 LPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGF
:::: ::: :::::. :: .:::.:::: . : :.:.: :.:.:.:.::::: : .
CCDS18 TPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRL
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB6 SCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQT
.: ::::: :::::::.::::::.::: ::::::.. .: ::::.:::. ...: : .
CCDS18 NCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECET-TNECREDEM
300 310 320 330 340
300 310 320 330 340 350
pF1KB6 CVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPAD
: :.:::.:: : : .::: . ::::.::.:: .::: :.:::..::.: :.::::.:
CCDS18 CWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSD
350 360 370 380 390 400
360 370 380 390 400 410
pF1KB6 VFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVT
.::::::..: .. :.:.:..:: .:.::.:: . :::::::.. ..::::...::::.:
CCDS18 IFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLT
410 420 430 440 450 460
420 430 440
pF1KB6 MNSLMSYRASSVLRLTVFVGAYTF
..:. ..:.:::::::..:: ..:
CCDS18 VSSIGTFRTSSVLRLTIIVGPFSF
470 480 490
>>CCDS9898.1 FBLN5 gene_id:10516|Hs108|chr14 (448 aa)
initn: 1703 init1: 791 opt: 1540 Z-score: 1054.7 bits: 204.3 E(32554): 2e-52
Smith-Waterman score: 1734; 50.1% identity (72.8% similar) in 453 aa overlap (8-443:1-448)
10 20 30 40 50 60
pF1KB6 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLT
.:: . .. .: : :: ... ..::.:.. : .: .: :..:: :
CCDS98 MPGIKRILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSGQCLDIDECRT
10 20 30 40
70 80 90 100
pF1KB6 IPEACKGEMKCINHYGGYLCLPRSAAVINDLHGE-------GP-PPPVPPAQHPN-P---
:::::.:.: :.:. :::::.::. : ... :: : .:: . :: :
CCDS98 IPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTIS
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 ----CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVD
: ::. :....:::::::: :.: :.: : : :.: :.: ::: . .:.:
CCDS98 RPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLD
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 IDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTF
:::::: :::. :.:.:::. : :.::: :. ..::: ::::: :: : : :.::.:
CCDS98 IDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 LCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLA-TRLCQD
.::: ::::..:: :::.::::.: .:::..:::.:: . : :: :: :: .: :::
CCDS98 ICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 IDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSI
:.::: : :. ::: :..::..:.: :: :::...:.:::.::: :: ::.:: .:
CCDS98 INECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTI
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB6 VHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLAR
..: : ..: ::::::.::.:::. ::::: :::..:: .::.:: . .:: ::..:
CCDS98 LYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTR
350 360 370 380 390 400
410 420 430 440
pF1KB6 PVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
:. :::: :::::.:.:.....:.:::.:: ..:. : :
CCDS98 PIKGPREIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
410 420 430 440
>>CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256 aa)
initn: 602 init1: 326 opt: 664 Z-score: 460.0 bits: 95.8 E(32554): 2.7e-19
Smith-Waterman score: 738; 38.3% identity (58.1% similar) in 303 aa overlap (33-310:595-893)
10 20 30 40 50 60
pF1KB6 PCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIP
:: .:. ::. :. ..: ::::: . :
CCDS81 VEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP
570 580 590 600 610 620
70 80 90 100
pF1KB6 EAC-KGEMKCINHYGGYLCL------------PRSAAVIND-----LHGEGPPPPVPPAQ
: :. :.: :.: : :: . .:. : :.: :..
CCDS81 --CGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH
630 640 650 660 670 680
110 120 130 140 150 160
pF1KB6 HPNPCPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC-TCPDGYR-KIGP
. : ::: . . : :.::: . .: :. :.: :::..: .: ::: . :
CCDS81 YKCNCYPGYRLKASRPPVCEDIDECRDP-SSC-PDGKCENKPGSFKCIACQPGYRSQGGG
690 700 710 720 730 740
170 180 190 200 210
pF1KB6 ECVDIDEC-RYRYCQHR-CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR-C
: :..:: . :. : :::::::: : :. .:..:::.::.::. : :.. :
CCDS81 ACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGIC
750 760 770 780 790 800
220 230 240 250 260 270
pF1KB6 FNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLA
:. :.: :.: .::.: :: : :::::.. . :.: : . : ::::..:..
CCDS81 SNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG
810 820 830 840 850 860
280 290 300 310 320 330
pF1KB6 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCR
: ::::::: . : .: :..:.: ::
CCDS81 GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECY
870 880 890 900 910 920
340 350 360 370 380 390
pF1KB6 EQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSA
CCDS81 LNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQD
930 940 950 960 970 980
>>CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303 aa)
initn: 602 init1: 326 opt: 664 Z-score: 459.8 bits: 95.8 E(32554): 2.7e-19
Smith-Waterman score: 738; 38.3% identity (58.1% similar) in 303 aa overlap (33-310:595-893)
10 20 30 40 50 60
pF1KB6 PCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIP
:: .:. ::. :. ..: ::::: . :
CCDS44 VEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP
570 580 590 600 610 620
70 80 90 100
pF1KB6 EAC-KGEMKCINHYGGYLCL------------PRSAAVIND-----LHGEGPPPPVPPAQ
: :. :.: :.: : :: . .:. : :.: :..
CCDS44 --CGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH
630 640 650 660 670 680
110 120 130 140 150 160
pF1KB6 HPNPCPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC-TCPDGYR-KIGP
. : ::: . . : :.::: . .: :. :.: :::..: .: ::: . :
CCDS44 YKCNCYPGYRLKASRPPVCEDIDECRDP-SSC-PDGKCENKPGSFKCIACQPGYRSQGGG
690 700 710 720 730 740
170 180 190 200 210
pF1KB6 ECVDIDEC-RYRYCQHR-CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR-C
: :..:: . :. : :::::::: : :. .:..:::.::.::. : :.. :
CCDS44 ACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGIC
750 760 770 780 790 800
220 230 240 250 260 270
pF1KB6 FNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLA
:. :.: :.: .::.: :: : :::::.. . :.: : . : ::::..:..
CCDS44 SNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG
810 820 830 840 850 860
280 290 300 310 320 330
pF1KB6 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCR
: ::::::: . : .: :..:.: ::
CCDS44 GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECY
870 880 890 900 910 920
340 350 360 370 380 390
pF1KB6 EQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSA
CCDS44 LNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQD
930 940 950 960 970 980
>>CCDS30956.1 HMCN1 gene_id:83872|Hs108|chr1 (5635 aa)
initn: 493 init1: 307 opt: 620 Z-score: 423.0 bits: 91.1 E(32554): 3.1e-17
Smith-Waterman score: 620; 38.4% identity (58.9% similar) in 258 aa overlap (100-346:5083-5329)
70 80 90 100 110 120
pF1KB6 KCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS-CVDVDECA
. ... : :: :. :. :.: ::::
CCDS30 PFLVETLHASSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECA
5060 5070 5080 5090 5100 5110
130 140 150 160 170 180
pF1KB6 QALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRY-RYCQHR---CVNLPG
: . : :..::: :.: :.:: : : : ::::: :. : : : :
CCDS30 -AGNPC--SHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIG
5120 5130 5140 5150 5160
190 200 210 220 230 240
pF1KB6 SFRC--QCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFS
:.:: .: ::. .. :: :.:::. ..::.:::::. :.: : :. ::.:. : .
CCDS30 SYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLK--GRK
5170 5180 5190 5200 5210 5220
250 260 270 280 290
pF1KB6 CSDIDECSYSSYLCQYRCVNEPGRFSC--HCPQGYQLLATRLCQDIDECESGAHQCSEAQ
: :..:: . . .: : : ..: ::.:. . : :::::..:.::: :
CCDS30 CMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ
5230 5240 5250 5260 5270 5280
300 310 320 330 340 350
pF1KB6 TCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPA
: : .:.:::: : . : . . .: : : :.. :. .:.
CCDS30 ICENTRGSYRCV----CPRGYRSQGVGRP-CMDINE-CEQVPKPCAHQCSNTPGSFKCIC
5290 5300 5310 5320 5330 5340
360 370 380 390 400 410
pF1KB6 DVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMV
CCDS30 PPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEY
5350 5360 5370 5380 5390 5400
>>CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557 aa)
initn: 425 init1: 274 opt: 596 Z-score: 413.1 bits: 87.4 E(32554): 1.1e-16
Smith-Waterman score: 720; 36.0% identity (55.1% similar) in 350 aa overlap (33-340:498-840)
10 20 30 40 50 60
pF1KB6 PCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYT-ECTDGYEWDPDSQHCRDVNECLTI
:..:: : .:.. .:.. .: ::.:: .
CCDS74 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV
470 480 490 500 510 520
70 80 90 100
pF1KB6 PEACKGEMKCINHYGGYLCL--------PRSAAVINDLHGEGPPPPVPPAQHPN-P----
: : . .: : :.. :. ::.: .. . . ::: .. : :
CCDS74 PPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL
530 540 550 560 570 580
110 120 130 140 150 160
pF1KB6 --CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV-D
:: ::. . :: :::::.:. : :.:::::..:.:: :.: : : :
CCDS74 CVCPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKNLPGSFRCVCPAGFR--GSACEED
590 600 610 620 630 640
170 180 190 200 210
pF1KB6 IDECRYRY--C-QHRCVNLPGSFRCQCEPGFQL-GPNNRSCVDVNECDMGAP-CEQ-RCF
.::: . : :: : :::.: : ::. ::. : ::.:: . : : ::
CCDS74 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA-PCQDVDECARSPPPCTYGRCE
650 660 670 680 690 700
220 230 240 250 260 270
pF1KB6 NSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQ-YRCVNEPGRFSCH-CPQGYQLL
:. :.: : : .:.. . : : :.::: . : .::: :: :.:. ::.:..:
CCDS74 NTEGSFQCVCPMGFQPNTAGSECEDVDECE-NHLACPGQECVNSPGSFQCRTCPSGHHLH
710 720 730 740 750 760
280 290 300 310 320
pF1KB6 ATRLCQDIDECESGAHQCSEAQTCVNFHG--------GYR--------CVDTNRCVEPYI
: : :.::: ::: :. :.: .: ::: :.:.:.:.: .
CCDS74 RGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF
770 780 790 800 810 820
330 340 350 360 370 380
pF1KB6 QVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRA
...:: .. : :
CCDS74 CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICP
830 840 850 860 870 880
>>CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19 (1587 aa)
initn: 425 init1: 274 opt: 596 Z-score: 413.0 bits: 87.4 E(32554): 1.1e-16
Smith-Waterman score: 720; 36.0% identity (55.1% similar) in 350 aa overlap (33-340:528-870)
10 20 30 40 50 60
pF1KB6 PCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYT-ECTDGYEWDPDSQHCRDVNECLTI
:..:: : .:.. .:.. .: ::.:: .
CCDS74 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV
500 510 520 530 540 550
70 80 90 100
pF1KB6 PEACKGEMKCINHYGGYLCL--------PRSAAVINDLHGEGPPPPVPPAQHPN-P----
: : . .: : :.. :. ::.: .. . . ::: .. : :
CCDS74 PPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL
560 570 580 590 600 610
110 120 130 140 150 160
pF1KB6 --CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV-D
:: ::. . :: :::::.:. : :.:::::..:.:: :.: : : :
CCDS74 CVCPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKNLPGSFRCVCPAGFR--GSACEED
620 630 640 650 660 670
170 180 190 200 210
pF1KB6 IDECRYRY--C-QHRCVNLPGSFRCQCEPGFQL-GPNNRSCVDVNECDMGAP-CEQ-RCF
.::: . : :: : :::.: : ::. ::. : ::.:: . : : ::
CCDS74 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA-PCQDVDECARSPPPCTYGRCE
680 690 700 710 720 730
220 230 240 250 260 270
pF1KB6 NSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQ-YRCVNEPGRFSCH-CPQGYQLL
:. :.: : : .:.. . : : :.::: . : .::: :: :.:. ::.:..:
CCDS74 NTEGSFQCVCPMGFQPNTAGSECEDVDECE-NHLACPGQECVNSPGSFQCRTCPSGHHLH
740 750 760 770 780 790
280 290 300 310 320
pF1KB6 ATRLCQDIDECESGAHQCSEAQTCVNFHG--------GYR--------CVDTNRCVEPYI
: : :.::: ::: :. :.: .: ::: :.:.:.:.: .
CCDS74 RGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF
800 810 820 830 840 850
330 340 350 360 370 380
pF1KB6 QVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRA
...:: .. : :
CCDS74 CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICP
860 870 880 890 900 910
>>CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19 (1624 aa)
initn: 425 init1: 274 opt: 596 Z-score: 412.9 bits: 87.4 E(32554): 1.1e-16
Smith-Waterman score: 720; 36.0% identity (55.1% similar) in 350 aa overlap (33-340:565-907)
10 20 30 40 50 60
pF1KB6 PCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYT-ECTDGYEWDPDSQHCRDVNECLTI
:..:: : .:.. .:.. .: ::.:: .
CCDS74 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV
540 550 560 570 580 590
70 80 90 100
pF1KB6 PEACKGEMKCINHYGGYLCL--------PRSAAVINDLHGEGPPPPVPPAQHPN-P----
: : . .: : :.. :. ::.: .. . . ::: .. : :
CCDS74 PPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL
600 610 620 630 640 650
110 120 130 140 150 160
pF1KB6 --CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV-D
:: ::. . :: :::::.:. : :.:::::..:.:: :.: : : :
CCDS74 CVCPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKNLPGSFRCVCPAGFR--GSACEED
660 670 680 690 700 710
170 180 190 200 210
pF1KB6 IDECRYRY--C-QHRCVNLPGSFRCQCEPGFQL-GPNNRSCVDVNECDMGAP-CEQ-RCF
.::: . : :: : :::.: : ::. ::. : ::.:: . : : ::
CCDS74 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA-PCQDVDECARSPPPCTYGRCE
720 730 740 750 760
220 230 240 250 260 270
pF1KB6 NSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQ-YRCVNEPGRFSCH-CPQGYQLL
:. :.: : : .:.. . : : :.::: . : .::: :: :.:. ::.:..:
CCDS74 NTEGSFQCVCPMGFQPNTAGSECEDVDECE-NHLACPGQECVNSPGSFQCRTCPSGHHLH
770 780 790 800 810 820
280 290 300 310 320
pF1KB6 ATRLCQDIDECESGAHQCSEAQTCVNFHG--------GYR--------CVDTNRCVEPYI
: : :.::: ::: :. :.: .: ::: :.:.:.:.: .
CCDS74 RGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF
830 840 850 860 870 880
330 340 350 360 370 380
pF1KB6 QVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRA
...:: .. : :
CCDS74 CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICP
890 900 910 920 930 940
>>CCDS32232.1 FBN1 gene_id:2200|Hs108|chr15 (2871 aa)
initn: 723 init1: 288 opt: 594 Z-score: 408.8 bits: 87.5 E(32554): 1.9e-16
Smith-Waterman score: 637; 34.0% identity (55.9% similar) in 297 aa overlap (54-328:2402-2687)
30 40 50 60 70 80
pF1KB6 SASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACK-GEMKCINHYGGYLCLP
:..:: .: ..:. :: :.: :.: :.
CCDS32 GPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGE--CVNDRGSYHCIC
2380 2390 2400 2410 2420
90 100 110 120
pF1KB6 RSAAVIN-------DLH--GEGPPP-----PVPPAQHPNPCPPGY-EPDDQDSCVDVDEC
... . . ::. ...: : ... :: :: .: :: :.:::
CCDS32 KTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC
2430 2440 2450 2460 2470 2480
130 140 150 160 170 180
pF1KB6 AQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECR--YRYCQHR--CVNLPGS
: :.:. : : :.. : :: :. . :.: .:: : . : : :::
CCDS32 ATKQHNCQFL--CVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGS
2490 2500 2510 2520 2530 2540
190 200 210 220 230 240
pF1KB6 FRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSD
: :.:. ::.: .. :: ::.::. . :.. : : : . : : ::: : . .: :
CCDS32 FTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVD
2550 2560 2570 2580 2590 2600
250 260 270 280 290 300
pF1KB6 IDECSYSSYLCQ-YRCVNEPGRFSCHCPQGYQLLA-TRLCQDIDECESGAHQCSEAQTCV
.:: :...: : : : ..: :: :.: . ::::.:: :. :: . :
CCDS32 ENEC-LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG--CS
2610 2620 2630 2640 2650 2660
310 320 330 340 350 360
pF1KB6 NFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVF
: .::: : : :.......:.
CCDS32 NTEGGYLC----GCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKI
2670 2680 2690 2700 2710 2720
>--
initn: 477 init1: 210 opt: 597 Z-score: 410.8 bits: 87.9 E(32554): 1.5e-16
Smith-Waterman score: 619; 33.1% identity (51.6% similar) in 366 aa overlap (38-336:1957-2316)
10 20 30 40 50 60
pF1KB6 LPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKG
.:..::: ::.. : :.:::: :. : .
CCDS32 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC-A
1930 1940 1950 1960 1970 1980
70 80 90 100 110
pF1KB6 EMKCINHYGGYLCL-PRSAAVIN----DLHGEGPPPPV--------PPAQHPNPCPPGYE
: : :.: :. : . .. : :. : . .. :: :.
CCDS32 PGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFS
1990 2000 2010 2020 2030 2040
120 130 140
pF1KB6 PDDQDS-CVDV------------------------DECAQALHDC---RPSQDCHNLPG-
... : :. .:: ::. : . : . :
CCDS32 LSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDE
2050 2060 2070 2080 2090 2100
150 160 170 180 190 200
pF1KB6 SYQCTCPDGYRKI-GPE--CVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRS
... :: : : ::. ::.:::. :.: .:.: ::.::.: :. :. :.
CCDS32 AFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNE--
2110 2120 2130 2140 2150 2160
210 220 230 240 250
pF1KB6 CVDVNECDMGAPC-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCV
:::..::..: :: . : : : : : :..:.: ..: ::.::. . :: .:::
CCDS32 CVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCEDINECAQNPLLCAFRCV
2170 2180 2190 2200 2210 2220
260 270 280 290 300
pF1KB6 NEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQCSEAQT-CVNFHG--------GYR-
: : . :.:: :: : : .:.: :::: : :.:.: : : :. : ::.
CCDS32 NTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQR
2230 2240 2250 2260 2270 2280
310 320 330 340 350 360
pF1KB6 ------CVDTNRC-VEPYIQVSEN-RCLCPASNPLCREQPSSIVHRYMTITSERSVPADV
::: :.: ..: . :: ::: .. :
CCDS32 RPDGEGCVDENECQTKP--GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF
2290 2300 2310 2320 2330 2340
370 380 390 400 410 420
pF1KB6 FQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTM
CCDS32 TEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG
2350 2360 2370 2380 2390 2400
>--
initn: 483 init1: 227 opt: 595 Z-score: 409.4 bits: 87.6 E(32554): 1.7e-16
Smith-Waterman score: 614; 30.5% identity (52.4% similar) in 393 aa overlap (36-375:337-720)
10 20 30 40 50
pF1KB6 SCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWD--PDS----QHCRDVNEC-
:: :.: . :.: : : :...:
CCDS32 TVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCW
310 320 330 340 350 360
60 70 80 90 100 110
pF1KB6 ---LTI-PEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE
.:. :: : .. . .. :: :. .. . : ::::. : : :::.
CCDS32 SPGVTVAPEMCP--IRATEDFNK-LC---SVPMVIPGRPEYPPPPLGPIPPVLPVPPGFP
370 380 390 400 410 420
120 130 140 150
pF1KB6 PDDQDSC-------------------VDV-DECAQALHDCRPSQDCHNLPGSYQCTCPDG
: : :.: : : . . :. .. : ::::.: : :
CCDS32 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGR-CIPTPGSYRCECNKG
430 440 450 460 470
160 170 180 190 200 210
pF1KB6 YR-KIGPECVDIDECRYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGA
.. . ::.:.:::. : .:.: ::. :::. :.: . : :..:: . :
CCDS32 FQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGR
480 490 500 510 520 530
220 230 240 250 260 270
pF1KB6 PCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCP
:.. ::.:. :.: : :. :... ::: .: :.:::: .. . :.:: : :.: :
CCDS32 ICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICK
540 550 560 570 580 590
280 290 300 310 320
pF1KB6 QGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC---------VDTNRCVEPYI
:.:: . : :.::.:::. . : ... ::: :.::: .: ::. ..
CCDS32 PGFQLASDGRYCKDINECETPG-ICMNGR-CVNTDGSYRCECFPGLAVGLDGRVCVDTHM
600 610 620 630 640 650
330 340 350 360 370
pF1KB6 QVS------ENRCLCPASNPLCREQPSSIVHRYMTITSERSVPA-DVFQIQAT-SVYPGA
. . ...:. : . . . . .: . :: . . :: : ::
CCDS32 RSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGM
660 670 680 690 700 710
380 390 400 410 420 430
pF1KB6 YNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVL
.:
CCDS32 TSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD
720 730 740 750 760 770
>--
initn: 961 init1: 227 opt: 537 Z-score: 370.4 bits: 80.4 E(32554): 2.6e-14
Smith-Waterman score: 631; 33.4% identity (55.5% similar) in 344 aa overlap (39-340:1182-1515)
10 20 30 40 50 60
pF1KB6 PGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGE
:. ::. :: : :..:: . .: :
CCDS32 ACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC--E
1160 1170 1180 1190 1200
70 80 90 100 110
pF1KB6 MKCINHYGGYLC--------LP--RSAAVINDLHG-----EGPPPPVPPAQHPNPCPPGY
: : :.: : .: :: . :.. . .: :... : :.
CCDS32 TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF
1210 1220 1230 1240 1250 1260
120 130 140 150 160 170
pF1KB6 -EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY
.:. .::::.:: . : : :.: ::. : : :: .: :.::.::.
CCDS32 MASEDMKTCVDVNECDLNPNICL-SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEI
1270 1280 1290 1300 1310 1320
180 190 200 210 220
pF1KB6 --RYC-QHR-CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQR--CFNSYGT
. : .: :.: :::.:.: ::. .: . . :.:..::. :. : :. : :..:.
CCDS32 GAHNCGKHAVCTNTAGSFKCSCSPGW-IGDGIK-CTDLDECSNGTHMCSQHADCKNTMGS
1330 1340 1350 1360 1370 1380
230 240 250 260 270 280
pF1KB6 FLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCHCPQGYQLLAT-RLC
. : :..:: :::.:.:.:::: . :: . .:.: :: . :.: .:. : . :
CCDS32 YRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKAC
1390 1400 1410 1420 1430 1440
290 300 310 320
pF1KB6 QDIDECESGAHQCSEAQTCVNFHGGYRC---------------VDTNRCVEPYIQVSENR
.::::: : . : . :: :. : .:: .:.:.:..: .: :
CCDS32 EDIDEC-SLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGN-
1450 1460 1470 1480 1490 1500
330 340 350 360 370 380
pF1KB6 CLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGD
:. .. .: :
CCDS32 CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKAS
1510 1520 1530 1540 1550 1560
443 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:39:08 2016 done: Sat Nov 5 11:39:09 2016
Total Scan time: 3.390 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]