Result of FASTA (omim) for
pFN21AB4623
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4623, 520 aa
1>>>pF1KB4623 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0189+/-0.000443; mu= 20.3850+/- 0.027
mean_var=65.8367+/-13.460, 0's: 0 Z-trim(109.0): 23 B-trim: 945 in 1/52
Lambda= 0.158067
statistics sampled from 17161 (17172) to 17161 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.201), width: 16
Scan time: 6.840
The best scores are: opt bits E(85289)
NP_000427 (OMIM: 245050,601424) succinyl-CoA:3-ket ( 520) 3403 785.4 0
XP_016864983 (OMIM: 245050,601424) PREDICTED: succ ( 490) 2736 633.3 5e-181
NP_071403 (OMIM: 610289) succinyl-CoA:3-ketoacid c ( 517) 2577 597.0 4.3e-170
>>NP_000427 (OMIM: 245050,601424) succinyl-CoA:3-ketoaci (520 aa)
initn: 3403 init1: 3403 opt: 3403 Z-score: 4192.7 bits: 785.4 E(85289): 0
Smith-Waterman score: 3403; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KB4 MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 AIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 KGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK
430 440 450 460 470 480
490 500 510 520
pF1KB4 KKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
::::::::::::::::::::::::::::::::::::::::
NP_000 KKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
490 500 510 520
>>XP_016864983 (OMIM: 245050,601424) PREDICTED: succinyl (490 aa)
initn: 2732 init1: 2732 opt: 2736 Z-score: 3371.0 bits: 633.3 E(85289): 5e-181
Smith-Waterman score: 3149; 94.2% identity (94.2% similar) in 520 aa overlap (1-520:1-490)
10 20 30 40 50 60
pF1KB4 MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 AIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPG---
370 380 390 400 410
430 440 450 460 470 480
pF1KB4 KGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK
:::::::::::::::::::::::::::::::::
XP_016 ---------------------------NAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK
420 430 440 450
490 500 510 520
pF1KB4 KKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
::::::::::::::::::::::::::::::::::::::::
XP_016 KKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
460 470 480 490
>>NP_071403 (OMIM: 610289) succinyl-CoA:3-ketoacid coenz (517 aa)
initn: 2594 init1: 1386 opt: 2577 Z-score: 3174.7 bits: 597.0 E(85289): 4.3e-170
Smith-Waterman score: 2577; 74.4% identity (90.2% similar) in 519 aa overlap (1-519:1-516)
10 20 30 40 50 60
pF1KB4 MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVL
::::.::.: : . : ::: . .::. :.:: . ..:::.:::: :::: :::::.
NP_071 MAALRLLASVLGRGVPAGGSGLALSQGCARCFATSPRLRAKFYADPVEMVKDISDGATVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENA
.::::::::::::: :::.: :: : .::.:.::..::::::: ..:..:.: ::::::.
NP_071 IGGFGLCGIPENLIAALLRTRVKDLQVVSSNVGVEDFGLGLLLAARQVRRIVCSYVGENT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSV
: :::.::::.::::::::::::::::::::::::::::::::::::.::.:. :: .
NP_071 LCESQYLAGELELELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGAPIRYTPDGHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 AIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAET
:. :.:::::::::.::.::.:: .::::::.:::::::::.::.::::::.::::::..
NP_071 ALMSQPREVREFNGDHFLLERAIRADFALVKGWKADRAGNVVFRRSARNFNVPMCKAADV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDD
:.:::::::..::: :::::.:.::: :.:::.:::::::::.: :: ::.: . .:
NP_071 TAVEVEEIVEVGAFPPEDIHVPNIYVDRVIKGQKYEKRIERLTILKEEDGDAGKE---ED
250 260 270 280 290
310 320 330 340 350 360
pF1KB4 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD
.: :::.::::::::::::::::::::::::::::..::::.::::.:::::.: . :.:
NP_071 ARTRIIRRAALEFEDGMYANLGIGIPLLASNFISPSMTVHLHSENGILGLGPFPTEDEVD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMV
::::::::.:::.:::. ::.::.:::::::::..::::::::::::::::::::::: :
NP_071 ADLINAGKQTVTVLPGGCFFASDDSFAMIRGGHIQLTMLGAMQVSKYGDLANWMIPGKKV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 KGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK
:::::::::::: ::.:::::.: .: :. :::::::.:::::.::.::::::::::: .
NP_071 KGMGGAMDLVSSQKTRVVVTMQHCTKDNTPKIMEKCTMPLTGKRCVDRIITEKAVFDVHR
420 430 440 450 460 470
490 500 510 520
pF1KB4 KKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
:: ::: ::::::::::..::::: :::::.: ::::.:
NP_071 KKELTLRELWEGLTVDDIKKSTGCAFAVSPNLRPMQQVAP
480 490 500 510
520 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:56:31 2016 done: Sat Nov 5 05:56:32 2016
Total Scan time: 6.840 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]