Result of FASTA (omim) for
pFN21AE3938
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3938, 191 aa
1>>>pF1KE3938 191 - 191 aa - 191 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3464+/-0.000376; mu= 19.3546+/- 0.024
mean_var=91.4171+/-18.981, 0's: 0 Z-trim(115.3): 269 B-trim: 669 in 1/52
Lambda= 0.134141
statistics sampled from 25202 (25606) to 25202 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.3), width: 16
Scan time: 4.790
The best scores are: opt bits E(85289)
NP_001001349 (OMIM: 604497) NF-kappa-B inhibitor-i ( 191) 1259 253.2 1.9e-67
XP_005257308 (OMIM: 604497) PREDICTED: NF-kappa-B ( 191) 1259 253.2 1.9e-67
NP_060065 (OMIM: 604497) NF-kappa-B inhibitor-inte ( 191) 1259 253.2 1.9e-67
NP_001138399 (OMIM: 604497) NF-kappa-B inhibitor-i ( 191) 1259 253.2 1.9e-67
XP_005265133 (OMIM: 604496) PREDICTED: NF-kappa-B ( 192) 907 185.1 6e-47
XP_005265135 (OMIM: 604496) PREDICTED: NF-kappa-B ( 192) 907 185.1 6e-47
NP_065078 (OMIM: 604496) NF-kappa-B inhibitor-inte ( 192) 907 185.1 6e-47
XP_005265134 (OMIM: 604496) PREDICTED: NF-kappa-B ( 192) 907 185.1 6e-47
NP_001138400 (OMIM: 604497) NF-kappa-B inhibitor-i ( 135) 531 112.1 3.9e-25
NP_001138401 (OMIM: 604497) NF-kappa-B inhibitor-i ( 97) 365 79.8 1.5e-15
XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 257 59.3 4.4e-09
NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 257 59.3 4.4e-09
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 256 59.1 5e-09
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 256 59.1 5e-09
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 256 59.2 5.6e-09
NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 252 58.3 8.5e-09
NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 247 57.4 1.7e-08
NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 247 57.4 1.7e-08
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 244 56.8 2.6e-08
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 244 56.8 2.6e-08
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 244 56.8 2.6e-08
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 244 56.8 2.6e-08
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 244 56.8 2.6e-08
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 244 56.9 2.8e-08
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 244 56.9 2.8e-08
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 244 56.9 2.8e-08
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 241 56.2 3.9e-08
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 240 56.1 4.6e-08
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 231 54.3 1.5e-07
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 231 54.3 1.5e-07
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 231 54.3 1.5e-07
NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 228 53.7 2.1e-07
NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 228 53.7 2.1e-07
NP_789765 (OMIM: 109800,137550,162900,163200,18847 ( 170) 222 52.5 4.5e-07
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 222 52.5 4.7e-07
NP_055814 (OMIM: 612398) ras-related protein Rab-2 ( 225) 219 52.0 7.9e-07
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 218 51.7 8e-07
NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 214 51.0 1.4e-06
XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 214 51.0 1.4e-06
XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 214 51.0 1.4e-06
XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 214 51.0 1.4e-06
NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 214 51.0 1.4e-06
NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 214 51.0 1.4e-06
NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 214 51.0 1.4e-06
XP_016857450 (OMIM: 179520) PREDICTED: ras-related ( 195) 211 50.4 2.1e-06
XP_016857449 (OMIM: 179520) PREDICTED: ras-related ( 195) 211 50.4 2.1e-06
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 210 50.3 2.6e-06
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 210 50.3 2.7e-06
NP_001170785 (OMIM: 600098) ras-related protein R- ( 169) 207 49.5 3.3e-06
XP_016872852 (OMIM: 600098) PREDICTED: ras-related ( 182) 207 49.6 3.5e-06
>>NP_001001349 (OMIM: 604497) NF-kappa-B inhibitor-inter (191 aa)
initn: 1259 init1: 1259 opt: 1259 Z-score: 1332.0 bits: 253.2 E(85289): 1.9e-67
Smith-Waterman score: 1259; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
130 140 150 160 170 180
190
pF1KE3 RKNKGSGSLDG
:::::::::::
NP_001 RKNKGSGSLDG
190
>>XP_005257308 (OMIM: 604497) PREDICTED: NF-kappa-B inhi (191 aa)
initn: 1259 init1: 1259 opt: 1259 Z-score: 1332.0 bits: 253.2 E(85289): 1.9e-67
Smith-Waterman score: 1259; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
130 140 150 160 170 180
190
pF1KE3 RKNKGSGSLDG
:::::::::::
XP_005 RKNKGSGSLDG
190
>>NP_060065 (OMIM: 604497) NF-kappa-B inhibitor-interact (191 aa)
initn: 1259 init1: 1259 opt: 1259 Z-score: 1332.0 bits: 253.2 E(85289): 1.9e-67
Smith-Waterman score: 1259; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
130 140 150 160 170 180
190
pF1KE3 RKNKGSGSLDG
:::::::::::
NP_060 RKNKGSGSLDG
190
>>NP_001138399 (OMIM: 604497) NF-kappa-B inhibitor-inter (191 aa)
initn: 1259 init1: 1259 opt: 1259 Z-score: 1332.0 bits: 253.2 E(85289): 1.9e-67
Smith-Waterman score: 1259; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
130 140 150 160 170 180
190
pF1KE3 RKNKGSGSLDG
:::::::::::
NP_001 RKNKGSGSLDG
190
>>XP_005265133 (OMIM: 604496) PREDICTED: NF-kappa-B inhi (192 aa)
initn: 923 init1: 885 opt: 907 Z-score: 963.9 bits: 185.1 E(85289): 6e-47
Smith-Waterman score: 907; 71.4% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::...:
XP_005 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
:::::..:.:::.: :: .::.:::::... ::::::::::::::: ::::::.::::::
XP_005 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
: ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.:::
XP_005 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
130 140 150 160 170 180
180 190
pF1KE3 SRKNKGSGSLDG
.:::::...
XP_005 GRKNKGNSNSEN
190
>>XP_005265135 (OMIM: 604496) PREDICTED: NF-kappa-B inhi (192 aa)
initn: 923 init1: 885 opt: 907 Z-score: 963.9 bits: 185.1 E(85289): 6e-47
Smith-Waterman score: 907; 71.4% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::...:
XP_005 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
:::::..:.:::.: :: .::.:::::... ::::::::::::::: ::::::.::::::
XP_005 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
: ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.:::
XP_005 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
130 140 150 160 170 180
180 190
pF1KE3 SRKNKGSGSLDG
.:::::...
XP_005 GRKNKGNSNSEN
190
>>NP_065078 (OMIM: 604496) NF-kappa-B inhibitor-interact (192 aa)
initn: 923 init1: 885 opt: 907 Z-score: 963.9 bits: 185.1 E(85289): 6e-47
Smith-Waterman score: 907; 71.4% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::...:
NP_065 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
:::::..:.:::.: :: .::.:::::... ::::::::::::::: ::::::.::::::
NP_065 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
: ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.:::
NP_065 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
130 140 150 160 170 180
180 190
pF1KE3 SRKNKGSGSLDG
.:::::...
NP_065 GRKNKGNSNSEN
190
>>XP_005265134 (OMIM: 604496) PREDICTED: NF-kappa-B inhi (192 aa)
initn: 923 init1: 885 opt: 907 Z-score: 963.9 bits: 185.1 E(85289): 6e-47
Smith-Waterman score: 907; 71.4% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::...:
XP_005 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
:::::..:.:::.: :: .::.:::::... ::::::::::::::: ::::::.::::::
XP_005 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
: ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.:::
XP_005 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
130 140 150 160 170 180
180 190
pF1KE3 SRKNKGSGSLDG
.:::::...
XP_005 GRKNKGNSNSEN
190
>>NP_001138400 (OMIM: 604497) NF-kappa-B inhibitor-inter (135 aa)
initn: 528 init1: 528 opt: 531 Z-score: 572.2 bits: 112.1 E(85289): 3.9e-25
Smith-Waterman score: 761; 70.7% identity (70.7% similar) in 191 aa overlap (1-191:1-135)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQV---
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
:::::::
NP_001 -----------------------------------------------------TIVVLGN
60
130 140 150 160 170 180
pF1KE3 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
70 80 90 100 110 120
190
pF1KE3 RKNKGSGSLDG
:::::::::::
NP_001 RKNKGSGSLDG
130
>>NP_001138401 (OMIM: 604497) NF-kappa-B inhibitor-inter (97 aa)
initn: 365 init1: 365 opt: 365 Z-score: 400.1 bits: 79.8 E(85289): 1.5e-15
Smith-Waterman score: 365; 98.2% identity (100.0% similar) in 57 aa overlap (1-57:1-57)
10 20 30 40 50 60
pF1KE3 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
NP_001 LFSVWSCSRRRLTNPRTRRRSPSWSLATSVTYRSSGV
70 80 90
191 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:47:55 2016 done: Sun Nov 6 01:47:56 2016
Total Scan time: 4.790 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]