Result of FASTA (omim) for
pFN21AE4437
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4437, 453 aa
1>>>pF1KE4437 453 - 453 aa - 453 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7031+/-0.000363; mu= 15.5568+/- 0.023
mean_var=73.5250+/-14.314, 0's: 0 Z-trim(113.5): 70 B-trim: 0 in 0/54
Lambda= 0.149574
statistics sampled from 22837 (22907) to 22837 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.269), width: 16
Scan time: 8.250
The best scores are: opt bits E(85289)
NP_000682 (OMIM: 100660) aldehyde dehydrogenase, d ( 453) 2987 654.1 2.3e-187
NP_001128639 (OMIM: 100660) aldehyde dehydrogenase ( 453) 2987 654.1 2.3e-187
NP_001128640 (OMIM: 100660) aldehyde dehydrogenase ( 453) 2987 654.1 2.3e-187
XP_011522033 (OMIM: 100660) PREDICTED: aldehyde de ( 380) 2529 555.2 1.1e-157
NP_001317079 (OMIM: 100660) aldehyde dehydrogenase ( 380) 2529 555.2 1.1e-157
XP_005256580 (OMIM: 100660) PREDICTED: aldehyde de ( 570) 2142 471.8 2.1e-132
XP_005256579 (OMIM: 100660) PREDICTED: aldehyde de ( 570) 2142 471.8 2.1e-132
XP_005256581 (OMIM: 100660) PREDICTED: aldehyde de ( 570) 2142 471.8 2.1e-132
NP_000373 (OMIM: 270200,609523) fatty aldehyde deh ( 485) 2113 465.5 1.4e-130
XP_016879846 (OMIM: 270200,609523) PREDICTED: fatt ( 485) 2113 465.5 1.4e-130
XP_016879845 (OMIM: 270200,609523) PREDICTED: fatt ( 485) 2113 465.5 1.4e-130
XP_011522035 (OMIM: 270200,609523) PREDICTED: fatt ( 508) 2113 465.5 1.5e-130
NP_001026976 (OMIM: 270200,609523) fatty aldehyde ( 508) 2113 465.5 1.5e-130
XP_011522034 (OMIM: 270200,609523) PREDICTED: fatt ( 508) 2113 465.5 1.5e-130
XP_016879847 (OMIM: 270200,609523) PREDICTED: fatt ( 424) 1940 428.1 2.2e-119
XP_016879844 (OMIM: 270200,609523) PREDICTED: fatt ( 424) 1940 428.1 2.2e-119
NP_000685 (OMIM: 600466) aldehyde dehydrogenase fa ( 468) 1670 369.9 8.2e-102
NP_001154945 (OMIM: 600466) aldehyde dehydrogenase ( 468) 1670 369.9 8.2e-102
NP_001025181 (OMIM: 600466) aldehyde dehydrogenase ( 431) 1453 323.0 9.6e-88
NP_001026786 (OMIM: 601917) aldehyde dehydrogenase ( 385) 1351 301.0 3.7e-81
NP_000686 (OMIM: 601917) aldehyde dehydrogenase fa ( 385) 1351 301.0 3.7e-81
NP_001276988 (OMIM: 600466) aldehyde dehydrogenase ( 272) 1044 234.7 2.4e-61
NP_001276987 (OMIM: 600466) aldehyde dehydrogenase ( 351) 683 156.8 8.4e-38
NP_000684 (OMIM: 600463,615113) aldehyde dehydroge ( 512) 586 136.0 2.3e-31
NP_000680 (OMIM: 100640) retinal dehydrogenase 1 [ ( 501) 571 132.7 2.1e-30
NP_000681 (OMIM: 100650,610251) aldehyde dehydroge ( 517) 557 129.7 1.8e-29
XP_011516104 (OMIM: 100670) PREDICTED: aldehyde de ( 517) 552 128.6 3.8e-29
NP_000683 (OMIM: 100670) aldehyde dehydrogenase X, ( 517) 552 128.6 3.8e-29
NP_001193826 (OMIM: 603687) retinal dehydrogenase ( 497) 547 127.5 7.7e-29
NP_003879 (OMIM: 603687) retinal dehydrogenase 2 i ( 518) 547 127.6 8e-29
NP_733798 (OMIM: 603687) retinal dehydrogenase 2 i ( 422) 516 120.8 6.9e-27
NP_001191818 (OMIM: 100650,610251) aldehyde dehydr ( 470) 512 120.0 1.4e-26
XP_016874378 (OMIM: 613584) PREDICTED: mitochondri ( 777) 503 118.1 8.1e-26
XP_011536288 (OMIM: 613584) PREDICTED: mitochondri ( 777) 503 118.1 8.1e-26
NP_001029345 (OMIM: 613584) mitochondrial 10-formy ( 923) 503 118.2 9.4e-26
NP_001071 (OMIM: 271980,610045) succinate-semialde ( 535) 484 114.0 1e-24
NP_001257294 (OMIM: 600249) cytosolic 10-formyltet ( 801) 447 106.1 3.6e-22
XP_011510657 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 447 106.1 4e-22
XP_006713544 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 447 106.1 4e-22
NP_036322 (OMIM: 600249) cytosolic 10-formyltetrah ( 902) 447 106.1 4e-22
NP_001257293 (OMIM: 600249) cytosolic 10-formyltet ( 912) 447 106.1 4.1e-22
NP_000687 (OMIM: 602733) 4-trimethylaminobutyralde ( 518) 441 104.7 6.1e-22
NP_001280744 (OMIM: 600463,615113) aldehyde dehydr ( 405) 432 102.7 1.9e-21
XP_011507596 (OMIM: 602733) PREDICTED: 4-trimethyl ( 424) 416 99.2 2.2e-20
XP_016861103 (OMIM: 600249) PREDICTED: cytosolic 1 ( 828) 391 94.0 1.6e-18
XP_016861102 (OMIM: 600249) PREDICTED: cytosolic 1 ( 838) 391 94.0 1.6e-18
NP_733797 (OMIM: 603687) retinal dehydrogenase 2 i ( 480) 376 90.6 9.6e-18
NP_001188306 (OMIM: 107323,266100) alpha-aminoadip ( 511) 371 89.6 2.1e-17
NP_001173 (OMIM: 107323,266100) alpha-aminoadipic ( 539) 371 89.6 2.2e-17
XP_011541719 (OMIM: 107323,266100) PREDICTED: alph ( 404) 360 87.2 9.1e-17
>>NP_000682 (OMIM: 100660) aldehyde dehydrogenase, dimer (453 aa)
initn: 2987 init1: 2987 opt: 2987 Z-score: 3484.9 bits: 654.1 E(85289): 2.3e-187
Smith-Waterman score: 2987; 99.8% identity (100.0% similar) in 453 aa overlap (1-453:1-453)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
370 380 390 400 410 420
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
:::::::::::::::::::::::::::::::::
NP_000 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
430 440 450
>>NP_001128639 (OMIM: 100660) aldehyde dehydrogenase, di (453 aa)
initn: 2987 init1: 2987 opt: 2987 Z-score: 3484.9 bits: 654.1 E(85289): 2.3e-187
Smith-Waterman score: 2987; 99.8% identity (100.0% similar) in 453 aa overlap (1-453:1-453)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
370 380 390 400 410 420
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
:::::::::::::::::::::::::::::::::
NP_001 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
430 440 450
>>NP_001128640 (OMIM: 100660) aldehyde dehydrogenase, di (453 aa)
initn: 2987 init1: 2987 opt: 2987 Z-score: 3484.9 bits: 654.1 E(85289): 2.3e-187
Smith-Waterman score: 2987; 99.8% identity (100.0% similar) in 453 aa overlap (1-453:1-453)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
370 380 390 400 410 420
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
:::::::::::::::::::::::::::::::::
NP_001 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
430 440 450
>>XP_011522033 (OMIM: 100660) PREDICTED: aldehyde dehydr (380 aa)
initn: 2529 init1: 2529 opt: 2529 Z-score: 2952.0 bits: 555.2 E(85289): 1.1e-157
Smith-Waterman score: 2529; 99.7% identity (100.0% similar) in 380 aa overlap (74-453:1-380)
50 60 70 80 90 100
pF1KE4 LVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSE
::::::::::::::::::::::::::::::
XP_011 MIQKLPEWAADEPVEKTPQTQQDELYIHSE
10 20 30
110 120 130 140 150 160
pF1KE4 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLY
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLY
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 PVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 RIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG
280 290 300 310 320 330
410 420 430 440 450
pF1KE4 GVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
340 350 360 370 380
>>NP_001317079 (OMIM: 100660) aldehyde dehydrogenase, di (380 aa)
initn: 2529 init1: 2529 opt: 2529 Z-score: 2952.0 bits: 555.2 E(85289): 1.1e-157
Smith-Waterman score: 2529; 99.7% identity (100.0% similar) in 380 aa overlap (74-453:1-380)
50 60 70 80 90 100
pF1KE4 LVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSE
::::::::::::::::::::::::::::::
NP_001 MIQKLPEWAADEPVEKTPQTQQDELYIHSE
10 20 30
110 120 130 140 150 160
pF1KE4 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLY
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLY
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 PVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 RIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG
280 290 300 310 320 330
410 420 430 440 450
pF1KE4 GVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
340 350 360 370 380
>>XP_005256580 (OMIM: 100660) PREDICTED: aldehyde dehydr (570 aa)
initn: 2141 init1: 2141 opt: 2142 Z-score: 2498.0 bits: 471.8 E(85289): 2.1e-132
Smith-Waterman score: 2142; 98.5% identity (99.7% similar) in 328 aa overlap (127-453:243-570)
100 110 120 130 140 150
pF1KE4 ELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAI-AAGNAVVLKPSELSENMASLLATIIP
:.. .:::.:::::::::::::::::::::
XP_005 TVPRTHNGGEASGVVLGRAEPLVKYPGHRPGSVCSAGNSVVLKPSELSENMASLLATIIP
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE4 QYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKS
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE4 PCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGED
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE4 AKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEI
400 410 420 430 440 450
340 350 360 370 380 390
pF1KE4 FGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI
460 470 480 490 500 510
400 410 420 430 440 450
pF1KE4 TLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
520 530 540 550 560 570
>>XP_005256579 (OMIM: 100660) PREDICTED: aldehyde dehydr (570 aa)
initn: 2141 init1: 2141 opt: 2142 Z-score: 2498.0 bits: 471.8 E(85289): 2.1e-132
Smith-Waterman score: 2142; 98.5% identity (99.7% similar) in 328 aa overlap (127-453:243-570)
100 110 120 130 140 150
pF1KE4 ELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAI-AAGNAVVLKPSELSENMASLLATIIP
:.. .:::.:::::::::::::::::::::
XP_005 TVPRTHNGGEASGVVLGRAEPLVKYPGHRPGSVCSAGNSVVLKPSELSENMASLLATIIP
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE4 QYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKS
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE4 PCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGED
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE4 AKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEI
400 410 420 430 440 450
340 350 360 370 380 390
pF1KE4 FGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI
460 470 480 490 500 510
400 410 420 430 440 450
pF1KE4 TLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
520 530 540 550 560 570
>>XP_005256581 (OMIM: 100660) PREDICTED: aldehyde dehydr (570 aa)
initn: 2141 init1: 2141 opt: 2142 Z-score: 2498.0 bits: 471.8 E(85289): 2.1e-132
Smith-Waterman score: 2142; 98.5% identity (99.7% similar) in 328 aa overlap (127-453:243-570)
100 110 120 130 140 150
pF1KE4 ELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAI-AAGNAVVLKPSELSENMASLLATIIP
:.. .:::.:::::::::::::::::::::
XP_005 TVPRTHNGGEASGVVLGRAEPLVKYPGHRPGSVCSAGNSVVLKPSELSENMASLLATIIP
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE4 QYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKS
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE4 PCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGED
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE4 AKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEI
400 410 420 430 440 450
340 350 360 370 380 390
pF1KE4 FGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI
460 470 480 490 500 510
400 410 420 430 440 450
pF1KE4 TLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
520 530 540 550 560 570
>>NP_000373 (OMIM: 270200,609523) fatty aldehyde dehydro (485 aa)
initn: 2092 init1: 2092 opt: 2113 Z-score: 2465.2 bits: 465.5 E(85289): 1.4e-130
Smith-Waterman score: 2113; 67.9% identity (90.9% similar) in 439 aa overlap (8-446:5-443)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:.:.: :: :::.:::.::.::::::.:..::.:.... :.:::: :.:.:.:
NP_000 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
.::. :: ::..:...::::.. .::.:. :. :: ::. .::::::.::.::::: :
NP_000 SQEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
::::..:::::::::..:::::::: :..:: ..:::::.::: :::::: :::::::.:
NP_000 TIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::.:::.:.::::.: ::::::::::::::::::::.::.::::..::::.:::.::
NP_000 FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::.:::::::. :.::::: :.:...::::::. :.: :: :::. :::.:...:.::
NP_000 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::.:.:: : ::::::::.::::::.. :::::::::.:::: :....:::.:::.:::
NP_000 QKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
:::::.:: : :.::.:: :::::::..::::.:.::.:.::::::.::::.::::.::.
NP_000 PLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFD
360 370 380 390 400 410
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::.: ::.. : . . :.::::.
NP_000 TFSHQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAA
420 430 440 450 460 470
>>XP_016879846 (OMIM: 270200,609523) PREDICTED: fatty al (485 aa)
initn: 2092 init1: 2092 opt: 2113 Z-score: 2465.2 bits: 465.5 E(85289): 1.4e-130
Smith-Waterman score: 2113; 67.9% identity (90.9% similar) in 439 aa overlap (8-446:5-443)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:.:.: :: :::.:::.::.::::::.:..::.:.... :.:::: :.:.:.:
XP_016 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
.::. :: ::..:...::::.. .::.:. :. :: ::. .::::::.::.::::: :
XP_016 SQEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
::::..:::::::::..:::::::: :..:: ..:::::.::: :::::: :::::::.:
XP_016 TIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::.:::.:.::::.: ::::::::::::::::::::.::.::::..::::.:::.::
XP_016 FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::.:::::::. :.::::: :.:...::::::. :.: :: :::. :::.:...:.::
XP_016 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::.:.:: : ::::::::.::::::.. :::::::::.:::: :....:::.:::.:::
XP_016 QKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
:::::.:: : :.::.:: :::::::..::::.:.::.:.::::::.::::.::::.::.
XP_016 PLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFD
360 370 380 390 400 410
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::.: ::.. : . . :.::::.
XP_016 TFSHQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAA
420 430 440 450 460 470
453 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:40:29 2016 done: Mon Nov 7 17:40:30 2016
Total Scan time: 8.250 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]