Result of FASTA (omim) for
pFN21AE3642
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3642, 316 aa
1>>>pF1KE3642 316 - 316 aa - 316 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7262+/-0.000384; mu= 13.4066+/- 0.024
mean_var=71.2003+/-14.099, 0's: 0 Z-trim(113.1): 52 B-trim: 198 in 1/52
Lambda= 0.151996
statistics sampled from 22231 (22292) to 22231 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.261), width: 16
Scan time: 7.240
The best scores are: opt bits E(85289)
NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316) 2095 468.6 7.3e-132
XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391) 1593 358.6 1.2e-98
NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314) 1462 329.8 4.4e-90
NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313) 1452 327.6 2e-89
NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329) 1356 306.6 4.6e-83
XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347) 890 204.4 2.8e-52
XP_011544086 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 202) 884 203.0 4.3e-52
XP_016878593 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 178) 830 191.1 1.4e-48
NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290) 788 182.0 1.3e-45
XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175) 500 118.7 8.5e-27
XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 479 114.1 2e-25
NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 236 60.9 3.5e-09
NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 236 60.9 3.5e-09
NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 208 54.8 2e-07
NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 208 54.8 2e-07
XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 208 54.8 2.2e-07
NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 208 54.8 2.5e-07
XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 208 54.8 2.7e-07
NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 208 54.8 2.7e-07
XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 208 54.8 2.8e-07
XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 208 54.8 2.9e-07
XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 208 54.8 2.9e-07
XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 208 54.8 3.1e-07
XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226) 202 53.4 5e-07
NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263) 202 53.5 5.7e-07
NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234) 201 53.2 6e-07
NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 199 52.8 8.1e-07
NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 199 52.8 9.6e-07
XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 199 52.8 9.6e-07
XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 199 52.8 9.6e-07
XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 199 52.8 9.6e-07
NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 199 52.8 9.6e-07
XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 186 50.0 6.3e-06
NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 186 50.0 6.3e-06
NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 186 50.0 6.3e-06
NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 186 50.0 6.3e-06
NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 186 50.0 6.5e-06
NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 186 50.2 1.8e-05
XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 177 48.0 2.7e-05
XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 177 48.0 2.9e-05
XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 177 48.1 3.9e-05
XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 177 48.1 3.9e-05
NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 177 48.1 3.9e-05
XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 177 48.1 3.9e-05
XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 177 48.1 3.9e-05
NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 167 45.8 0.00014
NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 168 46.2 0.00027
NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 168 46.2 0.00027
NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 152 42.5 0.001
NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 152 42.5 0.0012
>>NP_066960 (OMIM: 191161) BTB/POZ domain-containing ada (316 aa)
initn: 2095 init1: 2095 opt: 2095 Z-score: 2488.3 bits: 468.6 E(85289): 7.3e-132
Smith-Waterman score: 2095; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE3 MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHVKRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHVKRY
250 260 270 280 290 300
310
pF1KE3 STYDDRQLGHQSTHRD
::::::::::::::::
NP_066 STYDDRQLGHQSTHRD
310
>>XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ domain- (391 aa)
initn: 1593 init1: 1593 opt: 1593 Z-score: 1892.0 bits: 358.6 E(85289): 1.2e-98
Smith-Waterman score: 1593; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)
10 20 30 40 50 60
pF1KE3 MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHVKRY
XP_016 GIAPAWVGEDTHPLCGGRGRAVTSTEQKGHGLGSFFQTRWNSQRPESMRRHSTSYSMRLP
250 260 270 280 290 300
>>NP_001304324 (OMIM: 613421) BTB/POZ domain-containing (314 aa)
initn: 1436 init1: 1336 opt: 1462 Z-score: 1738.2 bits: 329.8 E(85289): 4.4e-90
Smith-Waterman score: 1462; 70.7% identity (88.5% similar) in 314 aa overlap (1-311:4-314)
10 20 30 40 50
pF1KE3 MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAM
:::.. . : .: . ..::: . ..:::.:::::.:::::...::..:::::::
NP_001 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL
::::::::::.:::::::::::::::::::::: .. ::..:.::.::.:::::::.:::
NP_001 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSD
:. ::.:::..::.:.: :..:.::: :::..:: .:.::.:::::::::::::::::::
NP_001 VEECQAALQQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 DHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQ
:..::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 DNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 TKVEFPEARIYEETLNVLLYETP--RVPDNSLLEATSRSRSQASPSEDEETFELRDRVRR
::::::::::::::::.::::. : :::.:::::. . ... ...: : .::::
NP_001 TKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRR
250 260 270 280 290 300
300 310
pF1KE3 IHVKRYSTYDDRQLGHQSTHRD
::.:: ::: ::
NP_001 IHIKRP---DDRAHLHQ
310
>>NP_114160 (OMIM: 613421) BTB/POZ domain-containing ada (313 aa)
initn: 880 init1: 780 opt: 1452 Z-score: 1726.4 bits: 327.6 E(85289): 2e-89
Smith-Waterman score: 1452; 70.7% identity (88.2% similar) in 314 aa overlap (1-311:4-313)
10 20 30 40 50
pF1KE3 MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAM
:::.. . : .: . ..::: . ..:::.:::::.:::::...::..:::::::
NP_114 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL
::::::::::.:::::::::::::::::::::: .. ::..:.::.::.:::::::.:::
NP_114 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSD
:. ::.:::.: :.:.: :..:.::: :::..:: .:.::.:::::::::::::::::::
NP_114 VEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSD
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 DHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQ
:..::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_114 DNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 TKVEFPEARIYEETLNVLLYETP--RVPDNSLLEATSRSRSQASPSEDEETFELRDRVRR
::::::::::::::::.::::. : :::.:::::. . ... ...: : .::::
NP_114 TKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRR
240 250 260 270 280 290
300 310
pF1KE3 IHVKRYSTYDDRQLGHQSTHRD
::.:: ::: ::
NP_114 IHIKRP---DDRAHLHQ
300 310
>>NP_849194 (OMIM: 608947) BTB/POZ domain-containing ada (329 aa)
initn: 1389 init1: 1343 opt: 1356 Z-score: 1612.3 bits: 306.6 E(85289): 4.6e-83
Smith-Waterman score: 1361; 64.4% identity (84.4% similar) in 326 aa overlap (2-316:6-329)
10 20 30 40
pF1KE3 MSGDTCLCPASGAKPKLSGFKGG----GL-----GNKYVQLNVGGSLYYTTVRALT
:: . : :: ::.. : :: ..:::.:::::::.:::.:.::
NP_849 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAE
.:::::::::::.::::: ::.:::: :.::::::::::: .. ::.. .:. ::..:
NP_849 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 AKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNN
:.:::.:::.. :: :::.:... .:.: ::..:: .::..:. :..:::::::.:::::
NP_849 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 KYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTS
::::::.:::.:::::::::::.:::.::.::.:::.:::::::::::::::.:::::::
NP_849 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 IVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQ--ASPSEDEET
:::::::::::::::::::.:::::.:.::::: :: .:::::. . . :. .::::.
NP_849 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN
250 260 270 280 290 300
290 300 310
pF1KE3 FELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
: :::::::.:. :.:.: :.: . .:
NP_849 RE--HRVRRIHVRRHITHDERPHGQQIVFKD
310 320
>>XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ domain- (347 aa)
initn: 1344 init1: 841 opt: 890 Z-score: 1059.6 bits: 204.4 E(85289): 2.8e-52
Smith-Waterman score: 1315; 61.0% identity (79.9% similar) in 344 aa overlap (2-316:6-347)
10 20 30 40
pF1KE3 MSGDTCLCPASGAKPKLSGFKGG----GL-----GNKYVQLNVGGSLYYTTVRALT
:: . : :: ::.. : :: ..:::.:::::::.:::.:.::
XP_011 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAE
.:::::::::::.::::: ::.:::: :.::::::::::: .. ::.. .:. ::..:
XP_011 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE
70 80 90 100 110 120
110 120 130 140
pF1KE3 AKYYLIQGLVNMCQSALQ------------------DKKDSYQPVCNIPIITSLKEEERL
:.:::.:::.. :: ::: .:... .:.: ::..:: .::..:
XP_011 ARYYLVQGLIEDCQLALQVRAFGVPMPMFLGELPKQQKRETLSPLCLIPMVTSPREEQQL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE3 IESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEIC
. :..:::::::.:::::::::::.:::.:::::::::::.:::.::.::.:::.:::::
XP_011 LASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEIC
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE3 CWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEA
::::::::::.::::::::::::::::::::::::::.:::::.:.::::: :: .::::
XP_011 CWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEA
250 260 270 280 290 300
270 280 290 300 310
pF1KE3 TSRSRSQ--ASPSEDEETFELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
:. . . :. .::::. : :::::::.:. :.:.: :.: . .:
XP_011 TGGAAGAGGAGRGEDEENRE--HRVRRIHVRRHITHDERPHGQQIVFKD
310 320 330 340
>>XP_011544086 (OMIM: 608947) PREDICTED: BTB/POZ domain- (202 aa)
initn: 863 init1: 841 opt: 884 Z-score: 1056.2 bits: 203.0 E(85289): 4.3e-52
Smith-Waterman score: 884; 68.6% identity (89.2% similar) in 194 aa overlap (125-316:11-202)
100 110 120 130 140 150
pF1KE3 PQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESST
:.:... .:.: ::..:: .::..:. :..
XP_011 MPMFLGELPKQQKRETLSPLCLIPMVTSPREEQQLLASTS
10 20 30 40
160 170 180 190 200 210
pF1KE3 KPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFY
:::::::.:::::::::::.:::.:::::::::::.:::.::.::.:::.::::::::::
XP_011 KPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFY
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE3 GQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSR
:::::.::::::::::::::::::::::::::.:::::.:.::::: :: .:::::. .
XP_011 GQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAA
110 120 130 140 150 160
280 290 300 310
pF1KE3 SQ--ASPSEDEETFELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
. :. .::::. : :::::::.:. :.:.: :.: . .:
XP_011 GAGGAGRGEDEENRE--HRVRRIHVRRHITHDERPHGQQIVFKD
170 180 190 200
>>XP_016878593 (OMIM: 608947) PREDICTED: BTB/POZ domain- (178 aa)
initn: 842 init1: 820 opt: 830 Z-score: 993.1 bits: 191.1 E(85289): 1.4e-48
Smith-Waterman score: 830; 70.6% identity (89.4% similar) in 180 aa overlap (139-316:1-178)
110 120 130 140 150 160
pF1KE3 KYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNK
..:: .::..:. :..:::::::.::::::
XP_016 MVTSPREEQQLLASTSKPVVKLLHNRSNNK
10 20 30
170 180 190 200 210 220
pF1KE3 YSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSI
:::::.:::.:::::::::::.:::.::.::.:::.:::::::::::::::.::::::::
XP_016 YSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 VYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQ--ASPSEDEETF
::::::::::::::::::.:::::.:.::::: :: .:::::. . . :. .::::.
XP_016 VYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENR
100 110 120 130 140 150
290 300 310
pF1KE3 ELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
: :::::::.:. :.:.: :.: . .:
XP_016 E--HRVRRIHVRRHITHDERPHGQQIVFKD
160 170
>>NP_001304328 (OMIM: 613421) BTB/POZ domain-containing (290 aa)
initn: 1058 init1: 558 opt: 788 Z-score: 940.0 bits: 182.0 E(85289): 1.3e-45
Smith-Waterman score: 1258; 64.0% identity (80.9% similar) in 314 aa overlap (1-311:4-290)
10 20 30 40 50
pF1KE3 MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAM
:::.. . : .: . ..::: . ..:::.:::::.:::::...::..:::::::
NP_001 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL
::::::::::.:::::::::::::::::::::: .. ::..:.::.::.:::::::.:::
NP_001 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSD
:. ::.:::.: :.:.: :..:.::: :::..:: .:.::.:::::::::::::::
NP_001 VEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYT----
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 DHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQ
::::::::::::::::::::::::.::::::::::::::::
NP_001 -------------------RVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
180 190 200 210
240 250 260 270 280 290
pF1KE3 TKVEFPEARIYEETLNVLLYETP--RVPDNSLLEATSRSRSQASPSEDEETFELRDRVRR
::::::::::::::::.::::. : :::.:::::. . ... ...: : .::::
NP_001 TKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRR
220 230 240 250 260 270
300 310
pF1KE3 IHVKRYSTYDDRQLGHQSTHRD
::.:: ::: ::
NP_001 IHIKRP---DDRAHLHQ
280 290
>>XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ domain- (175 aa)
initn: 507 init1: 474 opt: 500 Z-score: 602.1 bits: 118.7 E(85289): 8.5e-27
Smith-Waterman score: 505; 50.9% identity (73.0% similar) in 163 aa overlap (2-155:6-168)
10 20 30 40
pF1KE3 MSGDTCLCPASGAKPKLSGFKGG----GL-----GNKYVQLNVGGSLYYTTVRALT
:: . : :: ::.. : :: ..:::.:::::::.:::.:.::
XP_016 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAE
.:::::::::::.::::: ::.:::: :.::::::::::: .. ::.. .:. ::..:
XP_016 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 AKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNN
:.:::.:::.. :: :::.. : :. .. .: .. :. :..
XP_016 ARYYLVQGLIEDCQLALQSRAYSGFSSCSRNVFLQLVHQTRVQSRSSRCIWLSAS
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 KYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTS
316 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:47:35 2016 done: Mon Nov 7 02:47:36 2016
Total Scan time: 7.240 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]