Result of FASTA (omim) for
pFN21AE4337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4337, 348 aa
1>>>pF1KE4337 348 - 348 aa - 348 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6392+/-0.000393; mu= 20.2077+/- 0.024
mean_var=63.4991+/-13.026, 0's: 0 Z-trim(111.9): 42 B-trim: 0 in 0/50
Lambda= 0.160950
statistics sampled from 20540 (20582) to 20540 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.241), width: 16
Scan time: 7.590
The best scores are: opt bits E(85289)
NP_001008217 (OMIM: 230350,606953) UDP-glucose 4-e ( 348) 2343 552.8 4e-157
NP_000394 (OMIM: 230350,606953) UDP-glucose 4-epim ( 348) 2343 552.8 4e-157
NP_001121093 (OMIM: 230350,606953) UDP-glucose 4-e ( 348) 2343 552.8 4e-157
NP_055120 (OMIM: 616145,616146) dTDP-D-glucose 4,6 ( 350) 241 64.7 3.4e-10
NP_001491 (OMIM: 602884) GDP-mannose 4,6 dehydrata ( 372) 174 49.2 1.7e-05
XP_011519367 (OMIM: 616145,616146) PREDICTED: dTDP ( 318) 170 48.2 2.9e-05
XP_011519368 (OMIM: 616145,616146) PREDICTED: dTDP ( 318) 170 48.2 2.9e-05
NP_001291359 (OMIM: 616145,616146) dTDP-D-glucose ( 318) 170 48.2 2.9e-05
XP_006715129 (OMIM: 602884) PREDICTED: GDP-mannose ( 290) 161 46.1 0.00011
XP_011512804 (OMIM: 602884) PREDICTED: GDP-mannose ( 334) 159 45.7 0.00018
XP_011512802 (OMIM: 602884) PREDICTED: GDP-mannose ( 342) 153 44.3 0.00047
NP_001240775 (OMIM: 602884) GDP-mannose 4,6 dehydr ( 342) 153 44.3 0.00047
XP_011512808 (OMIM: 602884) PREDICTED: GDP-mannose ( 247) 151 43.7 0.00051
XP_011512807 (OMIM: 602884) PREDICTED: GDP-mannose ( 250) 151 43.7 0.00051
XP_011512809 (OMIM: 602884) PREDICTED: GDP-mannose ( 222) 150 43.4 0.00055
XP_011512805 (OMIM: 602884) PREDICTED: GDP-mannose ( 282) 151 43.8 0.00056
NP_001159592 (OMIM: 201810,613890) 3 beta-hydroxys ( 372) 149 43.4 0.00095
NP_000189 (OMIM: 201810,613890) 3 beta-hydroxyster ( 372) 149 43.4 0.00095
NP_000853 (OMIM: 109715) 3 beta-hydroxysteroid deh ( 373) 144 42.2 0.0021
NP_001315544 (OMIM: 109715) 3 beta-hydroxysteroid ( 373) 144 42.2 0.0021
XP_016856608 (OMIM: 109715) PREDICTED: 3 beta-hydr ( 375) 144 42.2 0.0021
>>NP_001008217 (OMIM: 230350,606953) UDP-glucose 4-epime (348 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2941.9 bits: 552.8 E(85289): 4e-157
Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
250 260 270 280 290 300
310 320 330 340
pF1KE4 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
310 320 330 340
>>NP_000394 (OMIM: 230350,606953) UDP-glucose 4-epimeras (348 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2941.9 bits: 552.8 E(85289): 4e-157
Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
250 260 270 280 290 300
310 320 330 340
pF1KE4 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
310 320 330 340
>>NP_001121093 (OMIM: 230350,606953) UDP-glucose 4-epime (348 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2941.9 bits: 552.8 E(85289): 4e-157
Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
250 260 270 280 290 300
310 320 330 340
pF1KE4 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
310 320 330 340
>>NP_055120 (OMIM: 616145,616146) dTDP-D-glucose 4,6-deh (350 aa)
initn: 267 init1: 120 opt: 241 Z-score: 304.1 bits: 64.7 E(85289): 3.4e-10
Smith-Waterman score: 302; 25.0% identity (56.2% similar) in 352 aa overlap (2-340:17-334)
10 20 30 40
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLE--AGYLPVVIDNFHNAFRGGG
:..::::::::.:.:: .. :.: .:. . .:..
NP_055 MSAACWEEPWGLPGGFAKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYC-----
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 SLPESLRRVQELTGR-SVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPL
::. .. .... . .: . :: :. .. ::. .. :.:::. : : . .
NP_055 ---ASLKNLETISNKQNYKFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 DYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKF
.. ::. :: :. . :..... :. :::. .::. : ::::..::
NP_055 EFTYVNVYGTHVLVSAAHEARVEKFIYVSTDEVYGGSLDKEFDESSPKQP-TNPYASSKA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 FIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMP-YVSQVAIGRRE
: : ... :. : . ...:. : :. :....: ..: . .:.
NP_055 AAE------CFVQSYWEQY---KFPVVITRSSNVYG--PHQYPEKVIPKFISLLQHNRK-
180 190 200 210
230 240 250 260 270 280
pF1KE4 ALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQM-
. :. : .:......:.... ...:.: : : .:::.::. .::.:.
NP_055 -CCIHGS------GLQTRNFLYATDVVEAFLTVLKKGKP--G-EIYNIGTNFEMSVVQLA
220 230 240 250 260
290 300 310 320 330
pF1KE4 ---VQAMEKASGKK-----IPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCED
.: ........ . : : : .:. : : . ::: . . .
NP_055 KELIQLIKETNSESEMENWVDY-VNDRPTNDMR--YPMKSEKIHGLGWRPKVPWKEGIKK
270 280 290 300 310 320
340
pF1KE4 LWRWQKQNPSGFGTQA
.: ..:
NP_055 TIEWYRENFHNWKNVEKALEPFPV
330 340 350
>>NP_001491 (OMIM: 602884) GDP-mannose 4,6 dehydratase i (372 aa)
initn: 83 init1: 60 opt: 174 Z-score: 219.6 bits: 49.2 E(85289): 1.7e-05
Smith-Waterman score: 174; 22.7% identity (54.2% similar) in 308 aa overlap (6-307:27-309)
10 20 30
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAF
:.:: .: ::. . ::: :: : ..:
NP_001 MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 RGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQ
. : . . . : ..... :. :. : ..... . . .... . : : .
NP_001 -NTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFD
70 80 90 100 110
100 110 120 130 140 150
pF1KE4 KPLDYYRVNLTGTIQLLEIMKAHGVKNLV-F--SSSATVYGNPQYLPLDEAHPTGGCTNP
:. .::..::. .:. :. : : : .:.. .::. : .: :. : .:
NP_001 LAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYP-RSP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 YGKSKFFIEEMIRDLCQADKTW--NAVLLRYFNPT-GAHASGCIGEDPQGIPNNLMPYVS
:: .:.. .. .. .: . . :..:. . .: ::. . .. :.
NP_001 YGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANF----------VTRKISRSVA
180 190 200 210 220
220 230 240 250 260 270
pF1KE4 QVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGT
.. .:. : ... :: :.. ::. : :: .. :. . .. . . ..::
NP_001 KIYLGQLECFSL-GN-LDAK-----RDWGH----AKDYVEAMWLMLQNDEPEDFVIATGE
230 240 250 260 270
280 290 300 310 320 330
pF1KE4 GYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDL
.:: ..:. :: : .. .. :..:. :
NP_001 VHSVREFVEKSFLHIGKTIVWE--GKNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGD
280 290 300 310 320 330
340
pF1KE4 WRWQKQNPSGFGTQA
NP_001 CTKAKQKLNWKPRVAFDELVREMVHADVELMRTNPNA
340 350 360 370
>>XP_011519367 (OMIM: 616145,616146) PREDICTED: dTDP-D-g (318 aa)
initn: 193 init1: 120 opt: 170 Z-score: 215.5 bits: 48.2 E(85289): 2.9e-05
Smith-Waterman score: 231; 23.4% identity (55.3% similar) in 304 aa overlap (48-340:25-302)
20 30 40 50 60 70
pF1KE4 TVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGR-SVEFEEMDILDQGALQRL
::. .. .... . .: . :: :. .. :
XP_011 MIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDSHFVKLL
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 FKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVY
:. .. :.:::. : : . ... ::. :: :. . :..... :. ::
XP_011 FETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIYVSTDEVY
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 GNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGC
:. .::. : ::::..:: : : ... :. : . ...:.
XP_011 GGSLDKEFDESSPKQP-TNPYASSKAAAE------CFVQSYWEQ---YKFPVVITRSSNV
120 130 140 150 160
200 210 220 230 240 250
pF1KE4 IGEDPQGIPNNLMP-YVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAAL
: :. :....: ..: . .:. . :. : .:......:.... ...:
XP_011 YG--PHQYPEKVIPKFISLLQHNRK--CCIHGS------GLQTRNFLYATDVVEAFLTVL
170 180 190 200 210
260 270 280 290 300
pF1KE4 RKLKEQCGCRIYNLGTGTGYSVLQM----VQAMEKASGKK-----IPYKVVARREGDVAA
.: : .:::.::. .::.:. .: ........ . : : : .:.
XP_011 KKGKPG---EIYNIGTNFEMSVVQLAKELIQLIKETNSESEMENWVDY-VNDRPTNDMR-
220 230 240 250 260
310 320 330 340
pF1KE4 CYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
: : . ::: . . . .: ..:
XP_011 -YPMKSEKIHGLGWRPKVPWKEGIKKTIEWYRENFHNWKNVEKALEPFPV
270 280 290 300 310
>>XP_011519368 (OMIM: 616145,616146) PREDICTED: dTDP-D-g (318 aa)
initn: 193 init1: 120 opt: 170 Z-score: 215.5 bits: 48.2 E(85289): 2.9e-05
Smith-Waterman score: 231; 23.4% identity (55.3% similar) in 304 aa overlap (48-340:25-302)
20 30 40 50 60 70
pF1KE4 TVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGR-SVEFEEMDILDQGALQRL
::. .. .... . .: . :: :. .. :
XP_011 MIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDSHFVKLL
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 FKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVY
:. .. :.:::. : : . ... ::. :: :. . :..... :. ::
XP_011 FETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIYVSTDEVY
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 GNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGC
:. .::. : ::::..:: : : ... :. : . ...:.
XP_011 GGSLDKEFDESSPKQP-TNPYASSKAAAE------CFVQSYWEQ---YKFPVVITRSSNV
120 130 140 150 160
200 210 220 230 240 250
pF1KE4 IGEDPQGIPNNLMP-YVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAAL
: :. :....: ..: . .:. . :. : .:......:.... ...:
XP_011 YG--PHQYPEKVIPKFISLLQHNRK--CCIHGS------GLQTRNFLYATDVVEAFLTVL
170 180 190 200 210
260 270 280 290 300
pF1KE4 RKLKEQCGCRIYNLGTGTGYSVLQM----VQAMEKASGKK-----IPYKVVARREGDVAA
.: : .:::.::. .::.:. .: ........ . : : : .:.
XP_011 KKGKPG---EIYNIGTNFEMSVVQLAKELIQLIKETNSESEMENWVDY-VNDRPTNDMR-
220 230 240 250 260
310 320 330 340
pF1KE4 CYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
: : . ::: . . . .: ..:
XP_011 -YPMKSEKIHGLGWRPKVPWKEGIKKTIEWYRENFHNWKNVEKALEPFPV
270 280 290 300 310
>>NP_001291359 (OMIM: 616145,616146) dTDP-D-glucose 4,6- (318 aa)
initn: 193 init1: 120 opt: 170 Z-score: 215.5 bits: 48.2 E(85289): 2.9e-05
Smith-Waterman score: 231; 23.4% identity (55.3% similar) in 304 aa overlap (48-340:25-302)
20 30 40 50 60 70
pF1KE4 TVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGR-SVEFEEMDILDQGALQRL
::. .. .... . .: . :: :. .. :
NP_001 MIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDSHFVKLL
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 FKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVY
:. .. :.:::. : : . ... ::. :: :. . :..... :. ::
NP_001 FETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIYVSTDEVY
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 GNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGC
:. .::. : ::::..:: : : ... :. : . ...:.
NP_001 GGSLDKEFDESSPKQP-TNPYASSKAAAE------CFVQSYWEQ---YKFPVVITRSSNV
120 130 140 150 160
200 210 220 230 240 250
pF1KE4 IGEDPQGIPNNLMP-YVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAAL
: :. :....: ..: . .:. . :. : .:......:.... ...:
NP_001 YG--PHQYPEKVIPKFISLLQHNRK--CCIHGS------GLQTRNFLYATDVVEAFLTVL
170 180 190 200 210
260 270 280 290 300
pF1KE4 RKLKEQCGCRIYNLGTGTGYSVLQM----VQAMEKASGKK-----IPYKVVARREGDVAA
.: : .:::.::. .::.:. .: ........ . : : : .:.
NP_001 KKGKPG---EIYNIGTNFEMSVVQLAKELIQLIKETNSESEMENWVDY-VNDRPTNDMR-
220 230 240 250 260
310 320 330 340
pF1KE4 CYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
: : . ::: . . . .: ..:
NP_001 -YPMKSEKIHGLGWRPKVPWKEGIKKTIEWYRENFHNWKNVEKALEPFPV
270 280 290 300 310
>>XP_006715129 (OMIM: 602884) PREDICTED: GDP-mannose 4,6 (290 aa)
initn: 83 init1: 60 opt: 161 Z-score: 204.8 bits: 46.1 E(85289): 0.00011
Smith-Waterman score: 161; 22.3% identity (54.7% similar) in 256 aa overlap (6-255:27-269)
10 20 30
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAF
:.:: .: ::. . ::: :: : ..:
XP_006 MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 RGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQ
. : . . . : ..... :. :. : ..... . . .... . : : .
XP_006 -NTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFD
70 80 90 100 110
100 110 120 130 140 150
pF1KE4 KPLDYYRVNLTGTIQLLEIMKAHGVKNLV-F--SSSATVYGNPQYLPLDEAHPTGGCTNP
:. .::..::. .:. :. : : : .:.. .::. : .: :. : .:
XP_006 LAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYP-RSP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 YGKSKFFIEEMIRDLCQADKTW--NAVLLRYFNPT-GAHASGCIGEDPQGIPNNLMPYVS
:: .:.. .. .. .: . . :..:. . .: ::. . .. :.
XP_006 YGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANF----------VTRKISRSVA
180 190 200 210 220
220 230 240 250 260 270
pF1KE4 QVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGT
.. .:. : ... :: .: ..::.. .. .: ..:
XP_006 KIYLGQLECFSL-GNLDAKRDWGHAKDYVEHTSSQMSHSSGLWILIGSLLSYTRNPIFKN
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE4 GYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDL
XP_006 HCS
290
>>XP_011512804 (OMIM: 602884) PREDICTED: GDP-mannose 4,6 (334 aa)
initn: 83 init1: 60 opt: 159 Z-score: 201.4 bits: 45.7 E(85289): 0.00018
Smith-Waterman score: 174; 22.7% identity (54.2% similar) in 308 aa overlap (6-307:27-309)
10 20 30
pF1KE4 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAF
:.:: .: ::. . ::: :: : ..:
XP_011 MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 RGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQ
. : . . . : ..... :. :. : ..... . . .... . : : .
XP_011 -NTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFD
70 80 90 100 110
100 110 120 130 140 150
pF1KE4 KPLDYYRVNLTGTIQLLEIMKAHGVKNLV-F--SSSATVYGNPQYLPLDEAHPTGGCTNP
:. .::..::. .:. :. : : : .:.. .::. : .: :. : .:
XP_011 LAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYP-RSP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 YGKSKFFIEEMIRDLCQADKTW--NAVLLRYFNPT-GAHASGCIGEDPQGIPNNLMPYVS
:: .:.. .. .. .: . . :..:. . .: ::. . .. :.
XP_011 YGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANF----------VTRKISRSVA
180 190 200 210 220
220 230 240 250 260 270
pF1KE4 QVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGT
.. .:. : ... :: :.. ::. : :: .. :. . .. . . ..::
XP_011 KIYLGQLECFSL-GN-LDAK-----RDWGH----AKDYVEAMWLMLQNDEPEDFVIATGE
230 240 250 260 270
280 290 300 310 320 330
pF1KE4 GYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDL
.:: ..:. :: : .. .. :..:. :
XP_011 VHSVREFVEKSFLHIGKTIVWE--GKNENEVGRCKETGKVHVTVDLKYYRPTEVVVCSL
280 290 300 310 320 330
340
pF1KE4 WRWQKQNPSGFGTQA
348 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:12:37 2016 done: Sun Nov 6 02:12:38 2016
Total Scan time: 7.590 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]