Result of FASTA (ccds) for
pFN21AE0162
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0162, 310 aa
1>>>pF1KE0162 310 - 310 aa - 310 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2184+/-0.000695; mu= 16.4810+/- 0.042
mean_var=68.4919+/-13.436, 0's: 0 Z-trim(110.1): 18 B-trim: 3 in 1/51
Lambda= 0.154973
statistics sampled from 11323 (11341) to 11323 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.348), width: 16
Scan time: 2.420
The best scores are: opt bits E(32554)
CCDS4526.1 SIRT5 gene_id:23408|Hs108|chr6 ( 310) 2134 485.6 2e-137
CCDS4527.1 SIRT5 gene_id:23408|Hs108|chr6 ( 299) 1952 444.9 3.5e-125
CCDS56398.1 SIRT5 gene_id:23408|Hs108|chr6 ( 202) 1387 318.5 2.7e-87
CCDS54966.1 SIRT5 gene_id:23408|Hs108|chr6 ( 292) 1295 298.0 5.6e-81
CCDS9194.1 SIRT4 gene_id:23409|Hs108|chr12 ( 314) 396 97.1 1.9e-20
>>CCDS4526.1 SIRT5 gene_id:23408|Hs108|chr6 (310 aa)
initn: 2134 init1: 2134 opt: 2134 Z-score: 2580.7 bits: 485.6 E(32554): 2e-137
Smith-Waterman score: 2134; 100.0% identity (100.0% similar) in 310 aa overlap (1-310:1-310)
10 20 30 40 50 60
pF1KE0 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 HCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEA
250 260 270 280 290 300
310
pF1KE0 LACHENETVS
::::::::::
CCDS45 LACHENETVS
310
>>CCDS4527.1 SIRT5 gene_id:23408|Hs108|chr6 (299 aa)
initn: 1952 init1: 1952 opt: 1952 Z-score: 2361.0 bits: 444.9 E(32554): 3.5e-125
Smith-Waterman score: 1952; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE0 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 HCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEA
:::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFSHLISISSLIIIKN
250 260 270 280 290
310
pF1KE0 LACHENETVS
>>CCDS56398.1 SIRT5 gene_id:23408|Hs108|chr6 (202 aa)
initn: 1387 init1: 1387 opt: 1387 Z-score: 1680.8 bits: 318.5 E(32554): 2.7e-87
Smith-Waterman score: 1387; 100.0% identity (100.0% similar) in 202 aa overlap (109-310:1-202)
80 90 100 110 120 130
pF1KE0 KWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVI
::::::::::::::::::::::::::::::
CCDS56 MGSKEPNAGHRAIAECETRLGKQGRRVVVI
10 20 30
140 150 160 170 180 190
pF1KE0 TQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDAS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 IPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE0 MFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALACHENETVS
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALACHENETVS
160 170 180 190 200
>>CCDS54966.1 SIRT5 gene_id:23408|Hs108|chr6 (292 aa)
initn: 1295 init1: 1295 opt: 1295 Z-score: 1567.3 bits: 298.0 E(32554): 5.6e-81
Smith-Waterman score: 1965; 94.2% identity (94.2% similar) in 310 aa overlap (1-310:1-292)
10 20 30 40 50 60
pF1KE0 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELA
:::::::: ::::::::::::::::::::::::::::::::::
CCDS54 CPALSGKG------------------CEEAGCGGLLRPHVVWFGENLDPAILEEVDRELA
190 200 210 220
250 260 270 280 290 300
pF1KE0 HCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEA
230 240 250 260 270 280
310
pF1KE0 LACHENETVS
::::::::::
CCDS54 LACHENETVS
290
>>CCDS9194.1 SIRT4 gene_id:23409|Hs108|chr12 (314 aa)
initn: 366 init1: 166 opt: 396 Z-score: 480.5 bits: 97.1 E(32554): 1.9e-20
Smith-Waterman score: 396; 27.2% identity (55.0% similar) in 309 aa overlap (8-303:20-314)
10 20 30 40
pF1KE0 MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFA
::. :. :: ::: .. ....:..
CCDS91 MKMSFALTFRSAKGRWIANPSQPCSKASIGLFVPASP--------PLDPEKVKELQRFIT
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 KAKHIVIISGAGVSAESGVPTFRGAG-GYWRKWQAQDLATPLAFAHNP--SRVWEFYHYR
.:......:::.:.:::.: .:. : . . . . . : .: :
CCDS91 LSKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 REVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTR
..:..:: .: :.. : : :. ..:::.: :: :::.. : :.:: . ..
CCDS91 WPQFSSHQPNPAHWALSTWE----KLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVL
120 130 140 150 160
170 180 190 200 210
pF1KE0 CTSCG------VVAENYK--SPICPALSGKGAPEPGT--QDASIPVEKLPRCEEAGCGGL
: .:: :. : .. .: : . ::. . .. .. ..: : . :::
CCDS91 CLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQ--CGGH
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE0 LRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFN
:.: ::.::....: .. : ... . : ::::.: :: . : . . .:.: .:
CCDS91 LKPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILN
230 240 250 260 270 280
280 290 300 310
pF1KE0 TETTPATNRFRFHFQGPCGTTLPEALACHENETVS
: . . ..... :: :: :
CCDS91 IGPTRSDDLACLKLNSRCGELLPLIDPC
290 300 310
310 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:22:03 2016 done: Thu Nov 3 23:22:04 2016
Total Scan time: 2.420 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]