Result of FASTA (omim) for
pFN21AE0155
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0155, 243 aa
1>>>pF1KE0155 243 - 243 aa - 243 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6183+/-0.000341; mu= 18.5264+/- 0.021
mean_var=66.1809+/-13.814, 0's: 0 Z-trim(114.7): 21 B-trim: 1482 in 1/52
Lambda= 0.157655
statistics sampled from 24634 (24655) to 24634 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.289), width: 16
Scan time: 6.100
The best scores are: opt bits E(85289)
NP_620417 (OMIM: 613766) secretory carrier-associa ( 235) 1600 372.4 3.9e-103
NP_001171582 (OMIM: 613766) secretory carrier-asso ( 235) 1600 372.4 3.9e-103
XP_006720484 (OMIM: 613766) PREDICTED: secretory c ( 235) 1600 372.4 3.9e-103
NP_001171583 (OMIM: 613766) secretory carrier-asso ( 235) 1600 372.4 3.9e-103
XP_006720483 (OMIM: 613766) PREDICTED: secretory c ( 253) 1600 372.4 4.1e-103
NP_524558 (OMIM: 613764) secretory carrier-associa ( 229) 976 230.5 2e-60
XP_016877478 (OMIM: 613766) PREDICTED: secretory c ( 164) 890 210.8 1.2e-54
XP_006720485 (OMIM: 613766) PREDICTED: secretory c ( 164) 890 210.8 1.2e-54
NP_001277158 (OMIM: 606911) secretory carrier-asso ( 312) 754 180.1 4e-45
NP_004857 (OMIM: 606911) secretory carrier-associa ( 338) 754 180.1 4.2e-45
XP_006711169 (OMIM: 606913) PREDICTED: secretory c ( 280) 751 179.4 5.9e-45
NP_443069 (OMIM: 606913) secretory carrier-associa ( 321) 751 179.4 6.5e-45
NP_005689 (OMIM: 606913) secretory carrier-associa ( 347) 751 179.4 6.9e-45
NP_001316468 (OMIM: 613764) secretory carrier-asso ( 185) 747 178.3 8.2e-45
XP_016877345 (OMIM: 606912) PREDICTED: secretory c ( 273) 747 178.4 1.1e-44
NP_005688 (OMIM: 606912) secretory carrier-associa ( 329) 747 178.5 1.2e-44
NP_001307707 (OMIM: 606912) secretory carrier-asso ( 372) 747 178.6 1.4e-44
XP_006711168 (OMIM: 606913) PREDICTED: secretory c ( 333) 682 163.7 3.6e-40
NP_001316469 (OMIM: 613764) secretory carrier-asso ( 195) 547 132.8 4.2e-31
XP_011542029 (OMIM: 606911) PREDICTED: secretory c ( 304) 418 103.7 4e-22
XP_016855480 (OMIM: 606913) PREDICTED: secretory c ( 204) 185 50.5 2.7e-06
>>NP_620417 (OMIM: 613766) secretory carrier-associated (235 aa)
initn: 989 init1: 945 opt: 1600 Z-score: 1972.7 bits: 372.4 E(85289): 3.9e-103
Smith-Waterman score: 1600; 96.7% identity (96.7% similar) in 243 aa overlap (1-243:1-235)
10 20 30 40 50 60
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
:::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_620 IQAVGIPGWGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
180 190 200 210 220 230
pF1KE0 NEM
:::
NP_620 NEM
>>NP_001171582 (OMIM: 613766) secretory carrier-associat (235 aa)
initn: 989 init1: 945 opt: 1600 Z-score: 1972.7 bits: 372.4 E(85289): 3.9e-103
Smith-Waterman score: 1600; 96.7% identity (96.7% similar) in 243 aa overlap (1-243:1-235)
10 20 30 40 50 60
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
:::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 IQAVGIPGWGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
180 190 200 210 220 230
pF1KE0 NEM
:::
NP_001 NEM
>>XP_006720484 (OMIM: 613766) PREDICTED: secretory carri (235 aa)
initn: 989 init1: 945 opt: 1600 Z-score: 1972.7 bits: 372.4 E(85289): 3.9e-103
Smith-Waterman score: 1600; 96.7% identity (96.7% similar) in 243 aa overlap (1-243:1-235)
10 20 30 40 50 60
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
:::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 IQAVGIPGWGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
180 190 200 210 220 230
pF1KE0 NEM
:::
XP_006 NEM
>>NP_001171583 (OMIM: 613766) secretory carrier-associat (235 aa)
initn: 989 init1: 945 opt: 1600 Z-score: 1972.7 bits: 372.4 E(85289): 3.9e-103
Smith-Waterman score: 1600; 96.7% identity (96.7% similar) in 243 aa overlap (1-243:1-235)
10 20 30 40 50 60
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
:::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 IQAVGIPGWGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
180 190 200 210 220 230
pF1KE0 NEM
:::
NP_001 NEM
>>XP_006720483 (OMIM: 613766) PREDICTED: secretory carri (253 aa)
initn: 989 init1: 945 opt: 1600 Z-score: 1972.3 bits: 372.4 E(85289): 4.1e-103
Smith-Waterman score: 1600; 96.7% identity (96.7% similar) in 243 aa overlap (1-243:19-253)
10 20 30 40
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYY
::::::::::::::::::::::::::::::::::::::::::
XP_006 MEFRTKRCGQATGPAGNIMAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 LWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 FSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIP
:::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_006 FSFMAFFFTFMAQLVISIIQAVGIPGWGVC--------GWIATISFFGTNIGSAVVMLIP
130 140 150 160 170
170 180 190 200 210 220
pF1KE0 TVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQG
180 190 200 210 220 230
230 240
pF1KE0 AMNQPQTQYSATPNYTYSNEM
:::::::::::::::::::::
XP_006 AMNQPQTQYSATPNYTYSNEM
240 250
>>NP_524558 (OMIM: 613764) secretory carrier-associated (229 aa)
initn: 978 init1: 705 opt: 976 Z-score: 1205.8 bits: 230.5 E(85289): 2e-60
Smith-Waterman score: 981; 55.8% identity (79.8% similar) in 242 aa overlap (1-242:1-227)
10 20 30 40 50 60
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA
:.:: :::::::::::.::::::.: .:: .: ..::.: :::. .::.:::..:::
NP_524 MSEKENNFPPLPKFIPVKPCFYQNFSDEIPVEHQVLVKRIYRLWMFYCATLGVNLIACLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI
: ::::..:::::::.::.:::::.:::::::.::::..::::.:::::: : ::.:...
NP_524 WWIGGGSGTNFGLAFVWLLLFTPCGYVCWFRPVYKAFRADSSFNFMAFFFIFGAQFVLTV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV
:::.:. :::.: ::...:.:: . :.:::::.:..::.: :.. ::. :
NP_524 IQAIGFSGWGAC--------GWLSAIGFFQYSPGAAVVMLLPAIMFSVSAAMMAIAIMKV
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS
:..:::.::::.::: ::.::.:.:: ..: : : . :. : ..:.: :
NP_524 HRIYRGAGGSFQKAQTEWNTGTWRNPPSREAQYNNFSGNSL-----PE--YPTVPSYPGS
180 190 200 210 220
pF1KE0 NEM
..
NP_524 GQWP
>>XP_016877478 (OMIM: 613766) PREDICTED: secretory carri (164 aa)
initn: 685 init1: 685 opt: 890 Z-score: 1102.0 bits: 210.8 E(85289): 1.2e-54
Smith-Waterman score: 890; 94.5% identity (94.5% similar) in 145 aa overlap (99-243:28-164)
70 80 90 100 110 120
pF1KE0 TNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPG
::::::::::::::::::::::::::::::
XP_016 MFLPRLRGRYSSPACQHDQAPLLPLDVTDSSFSFMAFFFTFMAQLVISIIQAVGIPG
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 WGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSG
:::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSG
60 70 80 90 100
190 200 210 220 230 240
pF1KE0 GSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
110 120 130 140 150 160
>>XP_006720485 (OMIM: 613766) PREDICTED: secretory carri (164 aa)
initn: 685 init1: 685 opt: 890 Z-score: 1102.0 bits: 210.8 E(85289): 1.2e-54
Smith-Waterman score: 890; 94.5% identity (94.5% similar) in 145 aa overlap (99-243:28-164)
70 80 90 100 110 120
pF1KE0 TNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPG
::::::::::::::::::::::::::::::
XP_006 MFLPRLRGRYSSPACQHDQAPLLPLDVTDSSFSFMAFFFTFMAQLVISIIQAVGIPG
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 WGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSG
:::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSG
60 70 80 90 100
190 200 210 220 230 240
pF1KE0 GSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
110 120 130 140 150 160
>>NP_001277158 (OMIM: 606911) secretory carrier-associat (312 aa)
initn: 796 init1: 315 opt: 754 Z-score: 931.1 bits: 180.1 E(85289): 4e-45
Smith-Waterman score: 754; 47.0% identity (79.5% similar) in 219 aa overlap (6-223:92-302)
10 20 30
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVS
::.::::. .:. ::::::: .::: . .
NP_001 LKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQK
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE0 MTKRLYYLWMLNSVTLAVNLVGCLAWL-IGGGGATNFGLAFLWLILFTPCSYVCWFRPIY
.: .:::::...::: .:. :::::. . .. :..:::..::..::::::.:::.::.:
NP_001 TVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLY
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE0 KAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFGTNIG
::..:::: :..:::... :... ..::.:. .:: : :::.... .. ::
NP_001 GAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNC--------GWISSLTGLNQNIP
190 200 210 220 230
160 170 180 190 200 210
pF1KE0 SAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQN
...:.: ...::. ::.:.. .. :: .:: .:.:: :::.:..::. .: :: :: :
NP_001 VGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAAN
240 250 260 270 280 290
220 230 240
pF1KE0 AAMGAAQGAMNQPQTQYSATPNYTYSNEM
:: ::..:
NP_001 AASTAASSAAQNAFKGNQI
300 310
>>NP_004857 (OMIM: 606911) secretory carrier-associated (338 aa)
initn: 796 init1: 315 opt: 754 Z-score: 930.7 bits: 180.1 E(85289): 4.2e-45
Smith-Waterman score: 754; 47.0% identity (79.5% similar) in 219 aa overlap (6-223:118-328)
10 20 30
pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVS
::.::::. .:. ::::::: .::: . .
NP_004 LKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQK
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE0 MTKRLYYLWMLNSVTLAVNLVGCLAWL-IGGGGATNFGLAFLWLILFTPCSYVCWFRPIY
.: .:::::...::: .:. :::::. . .. :..:::..::..::::::.:::.::.:
NP_004 TVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLY
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE0 KAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFGTNIG
::..:::: :..:::... :... ..::.:. .:: : :::.... .. ::
NP_004 GAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNC--------GWISSLTGLNQNIP
210 220 230 240 250
160 170 180 190 200 210
pF1KE0 SAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQN
...:.: ...::. ::.:.. .. :: .:: .:.:: :::.:..::. .: :: :: :
NP_004 VGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAAN
260 270 280 290 300 310
220 230 240
pF1KE0 AAMGAAQGAMNQPQTQYSATPNYTYSNEM
:: ::..:
NP_004 AASTAASSAAQNAFKGNQI
320 330
243 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:45:00 2016 done: Thu Nov 3 23:45:01 2016
Total Scan time: 6.100 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]