Result of FASTA (omim) for
pFN21AB8168
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8168, 304 aa
1>>>pF1KB8168 304 - 304 aa - 304 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6503+/-0.000352; mu= 6.2577+/- 0.022
mean_var=172.6781+/-36.045, 0's: 0 Z-trim(120.8): 43 B-trim: 2431 in 2/52
Lambda= 0.097601
statistics sampled from 36460 (36538) to 36460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.428), width: 16
Scan time: 8.940
The best scores are: opt bits E(85289)
NP_036390 (OMIM: 602953) hairy/enhancer-of-split r ( 304) 2004 293.7 3.1e-79
NP_001035798 (OMIM: 602953) hairy/enhancer-of-spli ( 308) 1986 291.2 1.8e-78
NP_001269780 (OMIM: 602953) hairy/enhancer-of-spli ( 214) 1330 198.7 8.7e-51
NP_036391 (OMIM: 604674) hairy/enhancer-of-split r ( 337) 853 131.7 2e-30
XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 747 116.7 5.7e-26
XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 747 116.7 5.7e-26
XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 747 116.7 5.7e-26
NP_055386 (OMIM: 609034) hairy/enhancer-of-split r ( 328) 745 116.4 7.5e-26
XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhan ( 300) 695 109.4 9.3e-24
NP_005515 (OMIM: 139605) transcription factor HES- ( 280) 352 61.0 3e-09
NP_066993 (OMIM: 608060) transcription factor HES- ( 221) 311 55.2 1.4e-07
NP_001135939 (OMIM: 608060) transcription factor H ( 247) 301 53.8 4e-07
NP_061115 (OMIM: 610331) transcription cofactor HE ( 224) 228 43.5 0.00047
NP_001136325 (OMIM: 610331) transcription cofactor ( 222) 223 42.8 0.00075
XP_005244828 (OMIM: 608060) PREDICTED: transcripti ( 189) 214 41.5 0.0016
NP_001010926 (OMIM: 607348) transcription factor H ( 166) 211 41.0 0.002
NP_115969 (OMIM: 608059,613686) transcription fact ( 225) 208 40.7 0.0033
NP_061962 (OMIM: 609970) transcription factor HES- ( 173) 198 39.2 0.0072
>>NP_036390 (OMIM: 602953) hairy/enhancer-of-split relat (304 aa)
initn: 2004 init1: 2004 opt: 2004 Z-score: 1543.6 bits: 293.7 E(85289): 3.1e-79
Smith-Waterman score: 2004; 99.7% identity (100.0% similar) in 304 aa overlap (1-304:1-304)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_036 LPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
250 260 270 280 290 300
pF1KB8 IGAF
::::
NP_036 IGAF
>>NP_001035798 (OMIM: 602953) hairy/enhancer-of-split re (308 aa)
initn: 1497 init1: 1497 opt: 1986 Z-score: 1529.8 bits: 291.2 E(85289): 1.8e-78
Smith-Waterman score: 1986; 98.4% identity (98.7% similar) in 308 aa overlap (1-304:1-308)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RRDRINNSLSELRRLVPSAFEKQ----GSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_001 RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LGPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 LGPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
250 260 270 280 290 300
300
pF1KB8 WGTEIGAF
::::::::
NP_001 WGTEIGAF
>>NP_001269780 (OMIM: 602953) hairy/enhancer-of-split re (214 aa)
initn: 1329 init1: 1329 opt: 1330 Z-score: 1032.7 bits: 198.7 E(85289): 8.7e-51
Smith-Waterman score: 1330; 90.8% identity (95.4% similar) in 217 aa overlap (88-304:3-214)
60 70 80 90 100 110
pF1KB8 EKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHA
::. ... .. .: .: .:::::::
NP_001 MPLEERNVFWLSKGNL-----TGDQGYFDAHA
10 20
120 130 140 150 160 170
pF1KB8 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB8 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB8 GPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_001 GPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
150 160 170 180 190 200
300
pF1KB8 GTEIGAF
:::::::
NP_001 GTEIGAF
210
>>NP_036391 (OMIM: 604674) hairy/enhancer-of-split relat (337 aa)
initn: 894 init1: 793 opt: 853 Z-score: 667.1 bits: 131.7 E(85289): 2e-30
Smith-Waterman score: 981; 54.1% identity (72.6% similar) in 340 aa overlap (1-302:1-335)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::: : ..:.:..::::.: .:. . . ::.. ::::.:::.:::.::::::::
NP_036 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
:::::::::::::::::.::::::::::::::::::::::::::...:::::::::::::
NP_036 RRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAM
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLG
:. :.::::::.::::::: .::::.::::::::::::.. :.::::: : ::
NP_036 DFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 HIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEA
: :...: : : :: :.. :.. .: :.: . : : . : .: : ..
NP_036 LHPHHWAAAFHHLPA---ALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 PALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA--
::: : .::..: : :. :: .:: . ...:. .. ::.:: :.: .: :::
NP_036 -ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAA
240 250 260 270 280 290
280 290 300
pF1KB8 -------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
.:: :.: :... .:::::::::.:
NP_036 AVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
300 310 320 330
>>XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhancer- (291 aa)
initn: 793 init1: 692 opt: 747 Z-score: 587.3 bits: 116.7 E(85289): 5.7e-26
Smith-Waterman score: 875; 55.6% identity (72.7% similar) in 293 aa overlap (48-302:1-289)
20 30 40 50 60 70
pF1KB8 TIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVP
.:::.:::::::::::::::::::::::::
XP_016 MARKKRRGIIEKRRRDRINNSLSELRRLVP
10 20 30
80 90 100 110 120 130
pF1KB8 SAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARY
.::::::::::::::::::::::::::...::::::::::::::. :.::::::.:::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 LSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLGHIP--WGTVFGHHPHIA
:: .::::.::::::::::::.. :.::::: : :: : :...: : :
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAA-
100 110 120 130 140
200 210 220 230 240
pF1KB8 HPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEAPALRAPPSGSLGP-VLP
:: :.. :.. .: :.: . : : . : .: : .. ::: : .::..: : :
XP_016 --LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS-ALRMPSTGSVAPCVPP
150 160 170 180 190 200
250 260 270 280
pF1KB8 VVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA---------LSP-------
. :: .:: . ...:. .. ::.:: :.: .: ::: .::
XP_016 LSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSAT
210 220 230 240 250 260
290 300
pF1KB8 SAPTQAANL--GKPYRPWGTEIGAF
:.: :... .:::::::::.:
XP_016 SSPQQTSSGTNNKPYRPWGTEVGAF
270 280 290
>>XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhancer- (291 aa)
initn: 793 init1: 692 opt: 747 Z-score: 587.3 bits: 116.7 E(85289): 5.7e-26
Smith-Waterman score: 875; 55.6% identity (72.7% similar) in 293 aa overlap (48-302:1-289)
20 30 40 50 60 70
pF1KB8 TIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVP
.:::.:::::::::::::::::::::::::
XP_016 MARKKRRGIIEKRRRDRINNSLSELRRLVP
10 20 30
80 90 100 110 120 130
pF1KB8 SAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARY
.::::::::::::::::::::::::::...::::::::::::::. :.::::::.:::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 LSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLGHIP--WGTVFGHHPHIA
:: .::::.::::::::::::.. :.::::: : :: : :...: : :
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAA-
100 110 120 130 140
200 210 220 230 240
pF1KB8 HPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEAPALRAPPSGSLGP-VLP
:: :.. :.. .: :.: . : : . : .: : .. ::: : .::..: : :
XP_016 --LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS-ALRMPSTGSVAPCVPP
150 160 170 180 190 200
250 260 270 280
pF1KB8 VVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA---------LSP-------
. :: .:: . ...:. .. ::.:: :.: .: ::: .::
XP_016 LSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSAT
210 220 230 240 250 260
290 300
pF1KB8 SAPTQAANL--GKPYRPWGTEIGAF
:.: :... .:::::::::.:
XP_016 SSPQQTSSGTNNKPYRPWGTEVGAF
270 280 290
>>XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhancer- (291 aa)
initn: 793 init1: 692 opt: 747 Z-score: 587.3 bits: 116.7 E(85289): 5.7e-26
Smith-Waterman score: 875; 55.6% identity (72.7% similar) in 293 aa overlap (48-302:1-289)
20 30 40 50 60 70
pF1KB8 TIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVP
.:::.:::::::::::::::::::::::::
XP_016 MARKKRRGIIEKRRRDRINNSLSELRRLVP
10 20 30
80 90 100 110 120 130
pF1KB8 SAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARY
.::::::::::::::::::::::::::...::::::::::::::. :.::::::.:::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 LSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLGHIP--WGTVFGHHPHIA
:: .::::.::::::::::::.. :.::::: : :: : :...: : :
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAA-
100 110 120 130 140
200 210 220 230 240
pF1KB8 HPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEAPALRAPPSGSLGP-VLP
:: :.. :.. .: :.: . : : . : .: : .. ::: : .::..: : :
XP_016 --LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS-ALRMPSTGSVAPCVPP
150 160 170 180 190 200
250 260 270 280
pF1KB8 VVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA---------LSP-------
. :: .:: . ...:. .. ::.:: :.: .: ::: .::
XP_016 LSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSAT
210 220 230 240 250 260
290 300
pF1KB8 SAPTQAANL--GKPYRPWGTEIGAF
:.: :... .:::::::::.:
XP_016 SSPQQTSSGTNNKPYRPWGTEVGAF
270 280 290
>>NP_055386 (OMIM: 609034) hairy/enhancer-of-split relat (328 aa)
initn: 723 init1: 565 opt: 745 Z-score: 585.1 bits: 116.4 E(85289): 7.5e-26
Smith-Waterman score: 745; 48.4% identity (69.1% similar) in 304 aa overlap (1-288:1-290)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::: . : :.::.: : :.: .: :.::. .: .:::. :::.::::::::
NP_055 MKRPK-EPSGSDGESDGPIDVGQE-----GQLSQMARPLSTPSSSQMQARKKRRGIIEKR
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
::::::.::::::::::.:::::::.::::::.::::::::::::..:: :.:::.:::.
NP_055 RRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAV
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIP
:.::.::::::.:: :::...:: .. .::.:.::.::::.::.. : . . :.
NP_055 DFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 WGTVFGHH-PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPP----S
: : : : . : : .: . : . ::. : : . :.: ::::. : .
NP_055 WPWSFFHSCPGL--PAL--SNQLAILGRVPSPVLP---GVSSPAYP-IPALRTAPLRRAT
180 190 200 210 220
240 250 260 270 280
pF1KB8 GSLGP----VLPVV-TSASKLSPPLLSSVASLSVFPFSFG--SFH---LLSPNALSPSAP
: . : ::: .:... . :: .. . : : : . : : ::. .. .: .:
NP_055 GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGP
230 240 250 260 270 280
290 300
pF1KB8 TQAANLGKPYRPWGTEIGAF
: .:
NP_055 TGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
290 300 310 320
>>XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhancer- (300 aa)
initn: 703 init1: 545 opt: 695 Z-score: 547.5 bits: 109.4 E(85289): 9.3e-24
Smith-Waterman score: 695; 49.2% identity (70.7% similar) in 266 aa overlap (39-288:5-262)
10 20 30 40 50 60
pF1KB8 SSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNS
.: .:::. :::..:::::::::::::.:
XP_005 MARPLSTPSSSQMQARKKHRGIIEKRRRDRINSS
10 20 30
70 80 90 100 110 120
pF1KB8 LSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFR
:::::::::.:::::::.::::::.::::::::::::..:: :.:::.:::.:.::.:::
XP_005 LSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIPWGTVFGHH
:::.:: :::...:: .. .::.:.::.::::.::.. : . . :. : : :
XP_005 ECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHS
100 110 120 130 140 150
190 200 210 220 230
pF1KB8 -PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPP----SGSLGP---
: . : : .: . : . ::. : : . :.: ::::. : .: . :
XP_005 CPGL--PAL--SNQLAILGRVPSPVLP---GVSSPAYP-IPALRTAPLRRATGIILPARR
160 170 180 190 200
240 250 260 270 280 290
pF1KB8 -VLPVV-TSASKLSPPLLSSVASLSVFPFSFG--SFH---LLSPNALSPSAPTQAANLGK
::: .:... . :: .. . : : : . : : ::. .. .: .:: .:
XP_005 NVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVA
210 220 230 240 250 260
300
pF1KB8 PYRPWGTEIGAF
XP_005 VPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
270 280 290 300
>>NP_005515 (OMIM: 139605) transcription factor HES-1 [H (280 aa)
initn: 390 init1: 151 opt: 352 Z-score: 286.9 bits: 61.0 E(85289): 3e-09
Smith-Waterman score: 352; 33.3% identity (58.8% similar) in 291 aa overlap (21-297:6-278)
10 20 30 40 50
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSM--SPTTSSQILARKRRRGIIE
.::.:.. . ..... .: :.:. :: . :.:
NP_005 MPADIMEKNSSSPVAATPASVNTTPDKPKTASE--HRKSSKPIME
10 20 30 40
60 70 80 90 100 110
pF1KB8 KRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
:::: :::.:::.:. :. .:..:..: .:::::.::.::: ::. :. : . ...
NP_005 KRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAAS--GA-HA
.. :: ::. ::.:.:: ::... .:.::..:: : .: .: . : :
NP_005 PSVLGKYRAGFSECMNEVTRFLSTCEGVNTE--VRTRLLGHLANCMTQINAMTYPGQPHP
110 120 130 140 150 160
180 190 200 210 220
pF1KB8 GLGHIPWGTVFG-----HHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPA
.: . : : : : : :.: : : :.: .::: ::
NP_005 AL-QAPPPPPPGPGGPQHAPFAPPPPLVPIPG----G--AAPPPGGAPCKLGSQAGEA--
170 180 190 200 210
230 240 250 260 270 280
pF1KB8 LRAPPSGSLGPVLPVVTSASKLSPPLLSSVASLSVFP-FSFGSFHLLSPNALSPSA-PTQ
: :.. :.:. . . : . . : :.: .. .: ..:::.:::. :.
NP_005 --AKVFGGF-QVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSL
220 230 240 250 260
290 300
pF1KB8 AANLGKPYRPWGTEIGAF
.:. . .:::
NP_005 TAD--SMWRPWRN
270 280
304 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:16:29 2016 done: Sat Nov 5 02:16:31 2016
Total Scan time: 8.940 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]