Result of FASTA (ccds) for
pFN21AB8168
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8168, 304 aa
1>>>pF1KB8168 304 - 304 aa - 304 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6372+/-0.000878; mu= 6.4596+/- 0.053
mean_var=162.0397+/-32.515, 0's: 0 Z-trim(113.1): 34 B-trim: 0 in 0/50
Lambda= 0.100754
statistics sampled from 13768 (13801) to 13768 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.424), width: 16
Scan time: 3.000
The best scores are: opt bits E(32554)
CCDS6225.1 HEY1 gene_id:23462|Hs108|chr8 ( 304) 2004 302.6 2.5e-82
CCDS43749.1 HEY1 gene_id:23462|Hs108|chr8 ( 308) 1986 300.0 1.5e-81
CCDS64915.1 HEY1 gene_id:23462|Hs108|chr8 ( 214) 1330 204.5 5.9e-53
CCDS5131.1 HEY2 gene_id:23493|Hs108|chr6 ( 337) 853 135.3 6.2e-32
CCDS439.1 HEYL gene_id:26508|Hs108|chr1 ( 328) 738 118.6 6.5e-27
CCDS75214.1 HELT gene_id:391723|Hs108|chr4 ( 242) 368 64.7 8e-11
>>CCDS6225.1 HEY1 gene_id:23462|Hs108|chr8 (304 aa)
initn: 2004 init1: 2004 opt: 2004 Z-score: 1591.6 bits: 302.6 E(32554): 2.5e-82
Smith-Waterman score: 2004; 99.7% identity (100.0% similar) in 304 aa overlap (1-304:1-304)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS62 LPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
250 260 270 280 290 300
pF1KB8 IGAF
::::
CCDS62 IGAF
>>CCDS43749.1 HEY1 gene_id:23462|Hs108|chr8 (308 aa)
initn: 1497 init1: 1497 opt: 1986 Z-score: 1577.4 bits: 300.0 E(32554): 1.5e-81
Smith-Waterman score: 1986; 98.4% identity (98.7% similar) in 308 aa overlap (1-304:1-308)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RRDRINNSLSELRRLVPSAFEKQ----GSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
CCDS43 RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LGPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS43 LGPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
250 260 270 280 290 300
300
pF1KB8 WGTEIGAF
::::::::
CCDS43 WGTEIGAF
>>CCDS64915.1 HEY1 gene_id:23462|Hs108|chr8 (214 aa)
initn: 1329 init1: 1329 opt: 1330 Z-score: 1064.2 bits: 204.5 E(32554): 5.9e-53
Smith-Waterman score: 1330; 90.8% identity (95.4% similar) in 217 aa overlap (88-304:3-214)
60 70 80 90 100 110
pF1KB8 EKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHA
::. ... .. .: .: .:::::::
CCDS64 MPLEERNVFWLSKGNL-----TGDQGYFDAHA
10 20
120 130 140 150 160 170
pF1KB8 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB8 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB8 GPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
CCDS64 GPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
150 160 170 180 190 200
300
pF1KB8 GTEIGAF
:::::::
CCDS64 GTEIGAF
210
>>CCDS5131.1 HEY2 gene_id:23493|Hs108|chr6 (337 aa)
initn: 894 init1: 793 opt: 853 Z-score: 686.8 bits: 135.3 E(32554): 6.2e-32
Smith-Waterman score: 981; 54.1% identity (72.6% similar) in 340 aa overlap (1-302:1-335)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::: : ..:.:..::::.: .:. . . ::.. ::::.:::.:::.::::::::
CCDS51 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
:::::::::::::::::.::::::::::::::::::::::::::...:::::::::::::
CCDS51 RRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAM
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLG
:. :.::::::.::::::: .::::.::::::::::::.. :.::::: : ::
CCDS51 DFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 HIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEA
: :...: : : :: :.. :.. .: :.: . : : . : .: : ..
CCDS51 LHPHHWAAAFHHLPA---ALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 PALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA--
::: : .::..: : :. :: .:: . ...:. .. ::.:: :.: .: :::
CCDS51 -ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAA
240 250 260 270 280 290
280 290 300
pF1KB8 -------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
.:: :.: :... .:::::::::.:
CCDS51 AVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
300 310 320 330
>>CCDS439.1 HEYL gene_id:26508|Hs108|chr1 (328 aa)
initn: 716 init1: 558 opt: 738 Z-score: 596.6 bits: 118.6 E(32554): 6.5e-27
Smith-Waterman score: 738; 48.0% identity (69.1% similar) in 304 aa overlap (1-288:1-290)
10 20 30 40 50 60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
::: . : :.::.: : :.: .: :.::. .: .:::. :::..:::::::
CCDS43 MKRPK-EPSGSDGESDGPIDVGQE-----GQLSQMARPLSTPSSSQMQARKKHRGIIEKR
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
::::::.::::::::::.:::::::.::::::.::::::::::::..:: :.:::.:::.
CCDS43 RRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAV
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIP
:.::.::::::.:: :::...:: .. .::.:.::.::::.::.. : . . :.
CCDS43 DFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 WGTVFGHH-PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPP----S
: : : : . : : .: . : . ::. : : . :.: ::::. : .
CCDS43 WPWSFFHSCPGL--PAL--SNQLAILGRVPSPVLP---GVSSPAYP-IPALRTAPLRRAT
180 190 200 210 220
240 250 260 270 280
pF1KB8 GSLGP----VLPVV-TSASKLSPPLLSSVASLSVFPFSFG--SFH---LLSPNALSPSAP
: . : ::: .:... . :: .. . : : : . : : ::. .. .: .:
CCDS43 GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGP
230 240 250 260 270 280
290 300
pF1KB8 TQAANLGKPYRPWGTEIGAF
: .:
CCDS43 TGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
290 300 310 320
>>CCDS75214.1 HELT gene_id:391723|Hs108|chr4 (242 aa)
initn: 321 init1: 209 opt: 368 Z-score: 307.8 bits: 64.7 E(32554): 8e-11
Smith-Waterman score: 374; 34.5% identity (60.6% similar) in 249 aa overlap (44-284:2-236)
20 30 40 50 60 70
pF1KB8 ELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRR---RGIIEKRRRDRINNSLS
:... ::: . .:::::::::: :.
CCDS75 MSDKLKERKRTPVSHKVIEKRRRDRINRCLN
10 20 30
80 90 100 110 120
pF1KB8 ELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAG-GKGYFDAHALA--MDYRSLGF
:: . :: :. ::.:.::::::::.:::..:. ::.: .: :. :: .: :.
CCDS75 ELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 RECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPWGTVFGHH
.::. ....::. .: ....: .:... :.. : : .: : :: .: :...
CCDS75 HECMKNLVHYLTTVERMETKDTKYARILAFLQSKA--RLGAEPAFPPLGSLPEPD-FSYQ
100 110 120 130 140
190 200 210 220 230 240
pF1KB8 PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPVLPV-VTS
: : : . ::. . ... : :: .. : :. :. : :: ..:
CCDS75 LHPAGPEF---AGHSPGEAAVFP-----QGSGAGPFPWPPGAARSPALPYLPSAPVPLAS
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB8 ASKLSPPLLSSVASLSVFPFSF-GSFHLLSPNALSPSAPTQAANLGKPYRPWGTEIGAF
.. :.:. : .:. ... : : ::::. .:
CCDS75 PAQQHSPFLTPVQGLDRHYLNLIGHAH---PNALNLHTPQHPPVL
210 220 230 240
304 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:16:29 2016 done: Sat Nov 5 02:16:29 2016
Total Scan time: 3.000 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]