Result of FASTA (ccds) for
pFN21AB5337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5337, 258 aa
1>>>pF1KB5337 258 - 258 aa - 258 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2996+/-0.00069; mu= 17.0210+/- 0.042
mean_var=111.3333+/-21.348, 0's: 0 Z-trim(114.7): 43 B-trim: 46 in 1/50
Lambda= 0.121552
statistics sampled from 15222 (15266) to 15222 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.469), width: 16
Scan time: 2.680
The best scores are: opt bits E(32554)
CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 ( 258) 1897 342.5 1.8e-94
CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7 ( 259) 530 102.7 2.6e-22
CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 ( 272) 450 88.7 4.4e-18
CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 297) 415 82.6 3.3e-16
CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 291) 398 79.7 2.6e-15
CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2 ( 325) 324 66.7 2.2e-11
>>CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 (258 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 1809.7 bits: 342.5 E(32554): 1.8e-94
Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KB5 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG
190 200 210 220 230 240
250
pF1KB5 LEPKGELDCHQLADSFRE
::::::::::::::::::
CCDS11 LEPKGELDCHQLADSFRE
250
>>CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7 (259 aa)
initn: 537 init1: 240 opt: 530 Z-score: 514.2 bits: 102.7 E(32554): 2.6e-22
Smith-Waterman score: 530; 34.7% identity (60.1% similar) in 248 aa overlap (10-250:14-252)
10 20 30 40 50
pF1KB5 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVG--CEELVREPGCG
:::.. : . : .: ::: :::: : :::. : :..: :::
CCDS55 MSEVPVARVWLVLLLLTVQVGVTAG-APWQCAPCSAEKLALC-PPVSASCSEVTRSAGCG
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQ
:: ::: :: ::: : ::. :: : : ..:::.: .:::.:.. .. :
CCDS55 CCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASA------
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTS---GGKMKVNGAPREDARPVPQ
: . :. :.. : .... . :. ... : . .:. . . .
CCDS55 PHAAEAGS-PESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKK
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 GS--CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV
. :. ::.:..: :: .: . :.. . .:::..:: .: .::. ..::. : ::::
CCDS55 WKEPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCV
180 190 200 210 220 230
230 240 250
pF1KB5 DRKTGVKLPGGLEPKGELDCHQLADSFRE
.: ..::. : .:. .:.
CCDS55 YPWNGKRIPGSPEIRGDPNCQIYFNVQN
240 250
>>CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 (272 aa)
initn: 623 init1: 373 opt: 450 Z-score: 438.1 bits: 88.7 E(32554): 4.4e-18
Smith-Waterman score: 658; 40.0% identity (62.9% similar) in 275 aa overlap (1-255:1-269)
10 20 30 40 50
pF1KB5 MLPLCLVAALLLA-AGPGPSLGDEAIHCPPCSEEKLARCRP-PVGCEELVREPGCGCCAT
:. : : :: : :::. :::. .:: ::.:. :. : : :.::: ::.::::::: :
CCDS24 MVLLTAVLLLLAAYAGPAQSLGSF-VHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMT
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELA----EIEAIQESLQ
:::. :. ::::: ::..:::: : . :::::.:.::.:::.. ... ..: .
CCDS24 CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSRE
60 70 80 90 100 110
120 130 140 150 160
pF1KB5 PSDKDEGDHPNNSFSPC---SAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARP---
. .. ....:: : : : : .:: . . : :. .. :.:
CCDS24 HEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRII
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 -VP-------QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALD
.: :: :. ... .:..: :: . . .:. :::::.: .. :::.:.
CCDS24 SAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYL---PNCDRKGFYKRKQCKPSRG
180 190 200 210 220 230
230 240 250
pF1KB5 GQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE
.:: ::::: : :.:::: :...:: . .:
CCDS24 RKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFDSSNVE
240 250 260 270
>>CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 (297 aa)
initn: 498 init1: 359 opt: 415 Z-score: 404.5 bits: 82.6 E(32554): 3.3e-16
Smith-Waterman score: 550; 35.2% identity (57.8% similar) in 270 aa overlap (13-250:31-290)
10 20 30 40
pF1KB5 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPV
.:: :: ...: ::. . ::.: ::
CCDS34 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGP-----VVRCEPCDARALAQCAPPP
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 G-CEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCM
. : ::::::::::: ::::. :.:::.:: :::::::: : .::..:. :.:.:.
CCDS34 AVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCV
60 70 80 90 100 110
110 120 130 140
pF1KB5 ELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDR--------------RCLQKHF----
. . . .. : :. :. : . . : .:: : . .:
CCDS34 NASAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLH
120 130 140 150 160 170
150 160 170 180 190
pF1KB5 AKI----RDRSTSGGKMKVNGAPR---------EDARPVPQGSCQSELHRALERLAASQS
.:: . .. .. ..::. . :. : . : :. :.. .:..: .
CCDS34 SKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNV
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB5 RTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCH
. . ..: ::::..: .. :::.:. .:: ::::: : : ::: ::. : :
CCDS34 LSPRGVHI---PNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPG-YTTKGKEDVH
240 250 260 270 280 290
pF1KB5 QLADSFRE
CCDS34 CYSMQSK
>>CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 (291 aa)
initn: 563 init1: 337 opt: 398 Z-score: 388.5 bits: 79.7 E(32554): 2.6e-15
Smith-Waterman score: 556; 35.6% identity (59.5% similar) in 264 aa overlap (13-250:31-284)
10 20 30 40
pF1KB5 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPV
.:: :: ...: ::. . ::.: ::
CCDS55 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGP-----VVRCEPCDARALAQCAPPP
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 G-CEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCM
. : ::::::::::: ::::. :.:::.:: :::::::: : .::..:. :.:.:.
CCDS55 AVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCV
60 70 80 90 100 110
110 120 130 140
pF1KB5 ELAEIEAIQESLQP--------SDKDEGDHPNNSFSPCSAHDRRCLQKHF----AKI---
. . . .. : : :...: .. :: . .: . .: .::
CCDS55 NASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIII
120 130 140 150 160 170
150 160 170 180 190
pF1KB5 -RDRSTSGGKMKVNGAPR---------EDARPVPQGSCQSELHRALERLAASQSRTHEDL
. .. .. ..::. . :. : . : :. :.. .:..: . . . .
CCDS55 KKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGV
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB5 YIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSF
.: ::::..: .. :::.:. .:: ::::: : : ::: ::. : :
CCDS55 HI---PNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPG-YTTKGKEDVHCYSMQS
240 250 260 270 280 290
pF1KB5 RE
CCDS55 K
>>CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2 (325 aa)
initn: 648 init1: 307 opt: 324 Z-score: 317.8 bits: 66.7 E(32554): 2.2e-11
Smith-Waterman score: 627; 37.9% identity (60.5% similar) in 301 aa overlap (1-258:17-315)
10 20 30 40
pF1KB5 MLPLCLVAALLLAAGPGPSLGDEAI-HCPPCSEEKLARCRPP--
.::: :. :: :.: : . :.. .::::. :.:: : ::
CCDS42 MLPRVGCPALPLPPPPLLPLLLL--LLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV
10 20 30 40 50
50 60 70 80
pF1KB5 --------------VGCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVE
. : :::::::::::..:: : :::::::::.:::::: : :
CCDS42 APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSE
60 70 80 90 100 110
90 100 110 120 130
pF1KB5 KPLHTLMHGQGVCMEL--AEIEAIQESLQPS--DKDEG-------DHPNNSFSPCSAHDR
::..:. :.:.: . :: : :.. . :..:: : : .. .. :
CCDS42 LPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGR
120 130 140 150 160 170
140 150 160 170 180
pF1KB5 RCLQ---KHFAKIRDRST-------SGGKMKVNGAPREDARPVPQGS-CQSELHRALERL
. :. :..: .:.. : .::: ... . :: : . ::.:: ..:::.
CCDS42 KPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERI
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB5 AA----SQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGL
.. .. : :: . :::::..: .. :::. .:.::::.::::. .:: . :.
CCDS42 STMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAP
240 250 260 270 280 290
250
pF1KB5 EPKGELDCHQLADSFRE
.:. .:: . . .:
CCDS42 TIRGDPECHLFYNEQQEARGVHTQRMQ
300 310 320
258 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:56:37 2016 done: Sat Nov 5 01:56:37 2016
Total Scan time: 2.680 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]