Result of FASTA (ccds) for
pFN21AE3134
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3134, 340 aa
1>>>pF1KE3134 340 - 340 aa - 340 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1694+/-0.000837; mu= 17.1250+/- 0.050
mean_var=66.4448+/-13.362, 0's: 0 Z-trim(106.5): 25 B-trim: 63 in 2/48
Lambda= 0.157342
statistics sampled from 9007 (9028) to 9007 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.277), width: 16
Scan time: 2.560
The best scores are: opt bits E(32554)
CCDS2927.1 NSUN3 gene_id:63899|Hs108|chr3 ( 340) 2314 534.0 6.5e-152
CCDS57996.1 NSUN4 gene_id:387338|Hs108|chr1 ( 335) 565 137.0 2.1e-32
CCDS534.1 NSUN4 gene_id:387338|Hs108|chr1 ( 384) 565 137.1 2.3e-32
CCDS58202.1 NOP2 gene_id:4839|Hs108|chr12 ( 628) 278 72.0 1.4e-12
CCDS44811.1 NOP2 gene_id:4839|Hs108|chr12 ( 808) 278 72.1 1.8e-12
CCDS58203.1 NOP2 gene_id:4839|Hs108|chr12 ( 812) 278 72.1 1.8e-12
CCDS58204.1 NOP2 gene_id:4839|Hs108|chr12 ( 845) 278 72.1 1.8e-12
>>CCDS2927.1 NSUN3 gene_id:63899|Hs108|chr3 (340 aa)
initn: 2314 init1: 2314 opt: 2314 Z-score: 2840.8 bits: 534.0 E(32554): 6.5e-152
Smith-Waterman score: 2314; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)
10 20 30 40 50 60
pF1KE3 MLTQLKAKSEGKLAKQICKVVLDHFEKQYSKELGDAWNTVREILTSPSCWQYAVLLNRFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 MLTQLKAKSEGKLAKQICKVVLDHFEKQYSKELGDAWNTVREILTSPSCWQYAVLLNRFN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YPFELEKDLHLKGYHTLSQGSLPNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 YPFELEKDLHLKGYHTLSQGSLPNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLPVLALELRDGEKVLDLCAAPGGKSIALLQCACPGYLHCNEYDSLRLRWLRQTLESFIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 LLPVLALELRDGEKVLDLCAAPGGKSIALLQCACPGYLHCNEYDSLRLRWLRQTLESFIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QPLINVIKVSELDGRKMGDAQPEMFDKVLVDAPCSNDRSWLFSSDSQKASCRISQRRNLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 QPLINVIKVSELDGRKMGDAQPEMFDKVLVDAPCSNDRSWLFSSDSQKASCRISQRRNLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LLQIELLRSAIKALRPGGILVYSTCTLSKAENQDVISEILNSHGNIMPMDIKGIARTCSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 LLQIELLRSAIKALRPGGILVYSTCTLSKAENQDVISEILNSHGNIMPMDIKGIARTCSH
250 260 270 280 290 300
310 320 330 340
pF1KE3 DFTFAPTGQECGLLVIPDKGKAWGPMYVAKLKKSWSTGKW
::::::::::::::::::::::::::::::::::::::::
CCDS29 DFTFAPTGQECGLLVIPDKGKAWGPMYVAKLKKSWSTGKW
310 320 330 340
>>CCDS57996.1 NSUN4 gene_id:387338|Hs108|chr1 (335 aa)
initn: 534 init1: 206 opt: 565 Z-score: 695.3 bits: 137.0 E(32554): 2.1e-32
Smith-Waterman score: 597; 35.8% identity (63.6% similar) in 335 aa overlap (29-333:3-333)
10 20 30 40 50
pF1KE3 MLTQLKAKSEGKLAKQICKVVLDHFEKQYSKELGDAWNTVREILTSPSCWQYAVLLNRF-
:: ..:: : ..: : : . .:..:.: :
CCDS57 MTYSVQFGDLWPSIRVSLLSEQ--KYGALVNNFA
10 20 30
60 70 80 90
pF1KE3 ---NYPFELE----KDL---HLKGYHTLSQGSLPNYPK--------SVKCY-LSRTP-GR
. .:: ::. .. .. :.:. :. ...:. ..: .:
CCDS57 AWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDISR
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE3 IPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAPGGKSIALLQCACPGYLH
.: : .. .:::..:::::::::: :. :. :::::::::::..:::: .: :
CCDS57 FPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLA
100 110 120 130 140 150
160 170 180 190 200 210
pF1KE3 CNEYDSLRLRWLRQTLESFIPQPLI--NVIKVSELDGRKMGDAQPEMFDKVLVDAPCSND
:. . :. :.. :.:..:. . : ..:. :::: :. . . .:.::::.::..:
CCDS57 ANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTD
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE3 RSWLFSSDSQ--KASCRISQRRNLPLLQIELLRSAIKALRPGGILVYSTCTLSKAENQDV
: : ... : : : ..:. ::.::..:: ... : .::: .:::::.::. .:. :
CCDS57 RHSLHEEENNIFKRS-RKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEYV
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE3 IS---EILNSHGNIMPM--DIKGIARTCSHDFTFAPTGQECGLLVIPDKGKAWGPMYVAK
.. :.: .. .:. . :. . :. : : . : : ::::. .:::: :
CCDS57 VQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQ-VGELVIPNLMANFGPMYFCK
280 290 300 310 320 330
340
pF1KE3 LKKSWSTGKW
...
CCDS57 MRRLT
>>CCDS534.1 NSUN4 gene_id:387338|Hs108|chr1 (384 aa)
initn: 534 init1: 206 opt: 565 Z-score: 694.4 bits: 137.1 E(32554): 2.3e-32
Smith-Waterman score: 614; 35.4% identity (64.1% similar) in 345 aa overlap (19-333:42-382)
10 20 30 40
pF1KE3 MLTQLKAKSEGKLAKQICKVVLDHFEKQYSKELGDAWNTVREILTSPS
...:..:. :: ..:: : ..: : : .
CCDS53 LLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLWPSIRVSLLSEQ
20 30 40 50 60 70
50 60 70 80
pF1KE3 CWQYAVLLNRF----NYPFELE----KDL---HLKGYHTLSQGSLPNYPK--------SV
.:..:.: : . .:: ::. .. .. :.:. :. ..
CCDS53 --KYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNL
80 90 100 110 120
90 100 110 120 130 140
pF1KE3 KCY-LSRTP-GRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAPGGKSI
.:. ..: .:.: : .. .:::..:::::::::: :. :. :::::::::::..
CCDS53 RCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE3 ALLQCACPGYLHCNEYDSLRLRWLRQTLESFIPQPLI--NVIKVSELDGRKMGDAQPEMF
:::: .: : :. . :. :.. :.:..:. . : ..:. :::: :. . . .
CCDS53 ALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTY
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE3 DKVLVDAPCSNDRSWLFSSDSQ--KASCRISQRRNLPLLQIELLRSAIKALRPGGILVYS
:.::::.::..:: : ... : : : ..:. ::.::..:: ... : .::: .:::
CCDS53 DRVLVDVPCTTDRHSLHEEENNIFKRS-RKKERQILPVLQVQLLAAGLLATKPGGHVVYS
250 260 270 280 290 300
270 280 290 300 310
pF1KE3 TCTLSKAENQDVIS---EILNSHGNIMPM--DIKGIARTCSHDFTFAPTGQECGLLVIPD
::.::. .:. :.. :.: .. .:. . :. . :. : : . : : ::::.
CCDS53 TCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQ-VGELVIPN
310 320 330 340 350 360
320 330 340
pF1KE3 KGKAWGPMYVAKLKKSWSTGKW
.:::: :...
CCDS53 LMANFGPMYFCKMRRLT
370 380
>>CCDS58202.1 NOP2 gene_id:4839|Hs108|chr12 (628 aa)
initn: 271 init1: 137 opt: 278 Z-score: 339.2 bits: 72.0 E(32554): 1.4e-12
Smith-Waterman score: 278; 31.2% identity (60.7% similar) in 234 aa overlap (113-333:362-582)
90 100 110 120 130 140
pF1KE3 PNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAP
:.: .:.:.:::.:: .. :..::.: ::
CCDS58 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP
340 350 360 370 380 390
150 160 170 180 190 200
pF1KE3 GGKSIALLQCA-CPGYLHCNEYDSLRLRWLRQTLESFIPQPLINVIKVSELDGRKMGDAQ
:::. . : : . :. .. ::. . .:. . . :.: .:. :::..
CCDS58 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRL---GVTNTI-ISHYDGRQF----
400 410 420 430 440
210 220 230 240 250
pF1KE3 PEM---FDKVLVDAPCSNDRSWLFSSDSQKASCRISQRRNL--PLLQIELLRSAIKAL--
:.. ::.::.:::::. . ..:.: . . ... : :: ::: ::: ..
CCDS58 PKVVGGFDRVLLDAPCSG--TGVISKDPAVKTNK-DEKDILRCAHLQKELLLSAIDSVNA
450 460 470 480 490 500
260 270 280 290 300
pF1KE3 --RPGGILVYSTCTLSKAENQDVISEILNSHG-NIMP--MDIKGIARTCSHDFTFAPTGQ
. :: ::: ::... ::. :.. :.... ..: .:. . : .. : :. .
CCDS58 TSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSLR
510 520 530 540 550 560
310 320 330 340
pF1KE3 ECGLLVIPDKGKAWGPMYVAKLKKSWSTGKW
. : . : ...::.::
CCDS58 STRRFY-PHTHNMDG-FFIAKFKKFSNSIPQSQTDGVLLCRSGWTAVVQSQLIATSTFQV
570 580 590 600 610
>>CCDS44811.1 NOP2 gene_id:4839|Hs108|chr12 (808 aa)
initn: 271 init1: 137 opt: 278 Z-score: 337.6 bits: 72.1 E(32554): 1.8e-12
Smith-Waterman score: 278; 31.2% identity (60.7% similar) in 234 aa overlap (113-333:362-582)
90 100 110 120 130 140
pF1KE3 PNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAP
:.: .:.:.:::.:: .. :..::.: ::
CCDS44 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP
340 350 360 370 380 390
150 160 170 180 190 200
pF1KE3 GGKSIALLQCA-CPGYLHCNEYDSLRLRWLRQTLESFIPQPLINVIKVSELDGRKMGDAQ
:::. . : : . :. .. ::. . .:. . . :.: .:. :::..
CCDS44 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRL---GVTNTI-ISHYDGRQF----
400 410 420 430 440
210 220 230 240 250
pF1KE3 PEM---FDKVLVDAPCSNDRSWLFSSDSQKASCRISQRRNL--PLLQIELLRSAIKAL--
:.. ::.::.:::::. . ..:.: . . ... : :: ::: ::: ..
CCDS44 PKVVGGFDRVLLDAPCSG--TGVISKDPAVKTNK-DEKDILRCAHLQKELLLSAIDSVNA
450 460 470 480 490 500
260 270 280 290 300
pF1KE3 --RPGGILVYSTCTLSKAENQDVISEILNSHG-NIMP--MDIKGIARTCSHDFTFAPTGQ
. :: ::: ::... ::. :.. :.... ..: .:. . : .. : :. .
CCDS44 TSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSLR
510 520 530 540 550 560
310 320 330 340
pF1KE3 ECGLLVIPDKGKAWGPMYVAKLKKSWSTGKW
. : . : ...::.::
CCDS44 STRRFY-PHTHNMDG-FFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQP
570 580 590 600 610
>>CCDS58203.1 NOP2 gene_id:4839|Hs108|chr12 (812 aa)
initn: 271 init1: 137 opt: 278 Z-score: 337.6 bits: 72.1 E(32554): 1.8e-12
Smith-Waterman score: 278; 31.2% identity (60.7% similar) in 234 aa overlap (113-333:366-586)
90 100 110 120 130 140
pF1KE3 PNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAP
:.: .:.:.:::.:: .. :..::.: ::
CCDS58 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP
340 350 360 370 380 390
150 160 170 180 190 200
pF1KE3 GGKSIALLQCA-CPGYLHCNEYDSLRLRWLRQTLESFIPQPLINVIKVSELDGRKMGDAQ
:::. . : : . :. .. ::. . .:. . . :.: .:. :::..
CCDS58 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRL---GVTNTI-ISHYDGRQF----
400 410 420 430 440
210 220 230 240 250
pF1KE3 PEM---FDKVLVDAPCSNDRSWLFSSDSQKASCRISQRRNL--PLLQIELLRSAIKAL--
:.. ::.::.:::::. . ..:.: . . ... : :: ::: ::: ..
CCDS58 PKVVGGFDRVLLDAPCSG--TGVISKDPAVKTNK-DEKDILRCAHLQKELLLSAIDSVNA
450 460 470 480 490 500
260 270 280 290 300
pF1KE3 --RPGGILVYSTCTLSKAENQDVISEILNSHG-NIMP--MDIKGIARTCSHDFTFAPTGQ
. :: ::: ::... ::. :.. :.... ..: .:. . : .. : :. .
CCDS58 TSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSLR
510 520 530 540 550 560
310 320 330 340
pF1KE3 ECGLLVIPDKGKAWGPMYVAKLKKSWSTGKW
. : . : ...::.::
CCDS58 STRRFY-PHTHNMDG-FFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQP
570 580 590 600 610 620
>>CCDS58204.1 NOP2 gene_id:4839|Hs108|chr12 (845 aa)
initn: 271 init1: 137 opt: 278 Z-score: 337.3 bits: 72.1 E(32554): 1.8e-12
Smith-Waterman score: 278; 31.2% identity (60.7% similar) in 234 aa overlap (113-333:399-619)
90 100 110 120 130 140
pF1KE3 PNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAP
:.: .:.:.:::.:: .. :..::.: ::
CCDS58 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP
370 380 390 400 410 420
150 160 170 180 190 200
pF1KE3 GGKSIALLQCA-CPGYLHCNEYDSLRLRWLRQTLESFIPQPLINVIKVSELDGRKMGDAQ
:::. . : : . :. .. ::. . .:. . . :.: .:. :::..
CCDS58 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRL---GVTNTI-ISHYDGRQF----
430 440 450 460 470 480
210 220 230 240 250
pF1KE3 PEM---FDKVLVDAPCSNDRSWLFSSDSQKASCRISQRRNL--PLLQIELLRSAIKAL--
:.. ::.::.:::::. . ..:.: . . ... : :: ::: ::: ..
CCDS58 PKVVGGFDRVLLDAPCSG--TGVISKDPAVKTNK-DEKDILRCAHLQKELLLSAIDSVNA
490 500 510 520 530
260 270 280 290 300
pF1KE3 --RPGGILVYSTCTLSKAENQDVISEILNSHG-NIMP--MDIKGIARTCSHDFTFAPTGQ
. :: ::: ::... ::. :.. :.... ..: .:. . : .. : :. .
CCDS58 TSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSLR
540 550 560 570 580 590
310 320 330 340
pF1KE3 ECGLLVIPDKGKAWGPMYVAKLKKSWSTGKW
. : . : ...::.::
CCDS58 STRRFY-PHTHNMDG-FFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQP
600 610 620 630 640 650
340 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:21:52 2016 done: Mon Nov 7 03:21:53 2016
Total Scan time: 2.560 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]