Result of FASTA (omim) for
pFN21AB8296
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8296, 422 aa
1>>>pF1KB8296 422 - 422 aa - 422 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2888+/-0.000354; mu= 3.5538+/- 0.022
mean_var=162.3232+/-32.239, 0's: 0 Z-trim(119.5): 37 B-trim: 241 in 2/54
Lambda= 0.100666
statistics sampled from 33533 (33571) to 33533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.394), width: 16
Scan time: 10.080
The best scores are: opt bits E(85289)
NP_065118 (OMIM: 602930) RNA exonuclease 4 isoform ( 422) 2796 417.9 2.4e-116
NP_001266280 (OMIM: 602930) RNA exonuclease 4 isof ( 329) 2170 326.9 4.6e-89
NP_001266279 (OMIM: 602930) RNA exonuclease 4 isof ( 285) 1883 285.2 1.4e-76
NP_001266278 (OMIM: 602930) RNA exonuclease 4 isof ( 250) 782 125.3 1.8e-28
NP_073604 (OMIM: 610177) apoptosis-enhancing nucle ( 325) 515 86.6 1e-16
XP_005255023 (OMIM: 610177) PREDICTED: apoptosis-e ( 325) 515 86.6 1e-16
XP_005255024 (OMIM: 610177) PREDICTED: apoptosis-e ( 325) 515 86.6 1e-16
XP_011520207 (OMIM: 610177) PREDICTED: apoptosis-e ( 325) 515 86.6 1e-16
XP_016877978 (OMIM: 610177) PREDICTED: apoptosis-e ( 325) 515 86.6 1e-16
NP_001290024 (OMIM: 611930) interferon-stimulated ( 353) 458 78.3 3.4e-14
XP_005245573 (OMIM: 611930) PREDICTED: interferon- ( 353) 458 78.3 3.4e-14
XP_006711624 (OMIM: 611930) PREDICTED: interferon- ( 353) 458 78.3 3.4e-14
XP_006711623 (OMIM: 611930) PREDICTED: interferon- ( 353) 458 78.3 3.4e-14
XP_016877979 (OMIM: 610177) PREDICTED: apoptosis-e ( 247) 428 73.9 5.2e-13
XP_006720708 (OMIM: 610177) PREDICTED: apoptosis-e ( 247) 428 73.9 5.2e-13
NP_001290162 (OMIM: 604533) interferon-stimulated ( 181) 389 68.1 2e-11
NP_001290163 (OMIM: 604533) interferon-stimulated ( 181) 389 68.1 2e-11
XP_005254956 (OMIM: 604533) PREDICTED: interferon- ( 181) 389 68.1 2e-11
NP_002192 (OMIM: 604533) interferon-stimulated gen ( 181) 389 68.1 2e-11
XP_006720551 (OMIM: 604533) PREDICTED: interferon- ( 181) 389 68.1 2e-11
XP_005245575 (OMIM: 611930) PREDICTED: interferon- ( 138) 251 48.0 1.7e-05
XP_016877637 (OMIM: 604533) PREDICTED: interferon- ( 161) 224 44.1 0.0003
NP_001290166 (OMIM: 604533) interferon-stimulated ( 161) 224 44.1 0.0003
NP_065746 (OMIM: 609614) RNA exonuclease 1 homolog (1221) 217 43.6 0.0033
XP_016882518 (OMIM: 609614) PREDICTED: RNA exonucl (1230) 217 43.6 0.0033
>>NP_065118 (OMIM: 602930) RNA exonuclease 4 isoform 1 [ (422 aa)
initn: 2796 init1: 2796 opt: 2796 Z-score: 2209.7 bits: 417.9 E(85289): 2.4e-116
Smith-Waterman score: 2796; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB8 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KAPEDFSQNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGEEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KAPEDFSQNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGEEMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 AKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 RPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSD
370 380 390 400 410 420
pF1KB8 DA
::
NP_065 DA
>>NP_001266280 (OMIM: 602930) RNA exonuclease 4 isoform (329 aa)
initn: 2170 init1: 2170 opt: 2170 Z-score: 1720.0 bits: 326.9 E(85289): 4.6e-89
Smith-Waterman score: 2170; 100.0% identity (100.0% similar) in 329 aa overlap (94-422:1-329)
70 80 90 100 110 120
pF1KB8 EDFSQNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGEEMPAGK
::::::::::::::::::::::::::::::
NP_001 MGSKKKPKIIQQNKKETSPQVKGEEMPAGK
10 20 30
130 140 150 160 170 180
pF1KB8 DQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRKAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRKAKE
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 AAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 LALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQ
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB8 GEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSGRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSGRPS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 LRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSDDA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSDDA
280 290 300 310 320
>>NP_001266279 (OMIM: 602930) RNA exonuclease 4 isoform (285 aa)
initn: 1883 init1: 1883 opt: 1883 Z-score: 1495.7 bits: 285.2 E(85289): 1.4e-76
Smith-Waterman score: 1883; 100.0% identity (100.0% similar) in 285 aa overlap (138-422:1-285)
110 120 130 140 150 160
pF1KB8 KETSPQVKGEEMPAGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDI
::::::::::::::::::::::::::::::
NP_001 MDRRAPVPRTKASGTEHNKKGTKERTNGDI
10 20 30
170 180 190 200 210 220
pF1KB8 VPERGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPERGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB8 SLSLVKEQAFGGLTRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSLVKEQAFGGLTRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQVKSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKYKPFKSQVKSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARD
220 230 240 250 260 270
410 420
pF1KB8 RRPLLTAPDHCSDDA
:::::::::::::::
NP_001 RRPLLTAPDHCSDDA
280
>>NP_001266278 (OMIM: 602930) RNA exonuclease 4 isoform (250 aa)
initn: 1277 init1: 778 opt: 782 Z-score: 632.3 bits: 125.3 E(85289): 1.8e-28
Smith-Waterman score: 990; 50.1% identity (53.9% similar) in 425 aa overlap (1-422:1-250)
10 20 30 40 50 60
pF1KB8 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 KAPEDFSQNWKALQE---WLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGE
::::::::::::::: : .. :: .: . : .:.:. ::.
NP_001 KAPEDFSQNWKALQEVPRWTGGRQYLAP-RP--VEQSTIRKEPR-------------KGQ
70 80 90 100
120 130 140 150 160 170
pF1KB8 EMPAGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHK
. ... .: :. :: :. :: : :.
NP_001 MVILFQNEGTS--SIRSG-KL-RRQPQPH-------------------------------
110 120
180 190 200 210 220 230
pF1KB8 KRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAF
:: ::
NP_001 ----------PPREE---------------------------------------------
130
240 250 260 270 280 290
pF1KB8 GGLTRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIR
NP_001 ------------------------------------------------------------
300 310 320 330 340 350
pF1KB8 PENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------LEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQV
140 150 160 170 180
360 370 380 390 400 410
pF1KB8 KSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDH
190 200 210 220 230 240
420
pF1KB8 CSDDA
:::::
NP_001 CSDDA
250
>>NP_073604 (OMIM: 610177) apoptosis-enhancing nuclease (325 aa)
initn: 498 init1: 385 opt: 515 Z-score: 421.1 bits: 86.6 E(85289): 1e-16
Smith-Waterman score: 515; 39.1% identity (67.8% similar) in 230 aa overlap (201-422:65-292)
180 190 200 210 220 230
pF1KB8 RGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLS
:. . :: . :::. ... : . ::. :
NP_073 RQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCS
40 50 60 70 80 90
240 250 260 270 280
pF1KB8 L--VKEQAFGGL-TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
. .: : : .. .:.::::::.::.:. : :: :::. .:. .::::..: :..
NP_073 RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
:::: ::: ...... ..:.:::. ..:::...::::::::...: ::... :::
NP_073 DYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQV---KSGRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWE
: :. .: ::. :. ..: .:: : : :..:: .::.:: .:. .::
NP_073 TYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWE
220 230 240 250 260 270
410 420
pF1KB8 SMARDRRPLLTAPDHCSDDA
. .. : : : :. :.
NP_073 Q--QEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
280 290 300 310 320
>>XP_005255023 (OMIM: 610177) PREDICTED: apoptosis-enhan (325 aa)
initn: 498 init1: 385 opt: 515 Z-score: 421.1 bits: 86.6 E(85289): 1e-16
Smith-Waterman score: 515; 39.1% identity (67.8% similar) in 230 aa overlap (201-422:65-292)
180 190 200 210 220 230
pF1KB8 RGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLS
:. . :: . :::. ... : . ::. :
XP_005 RQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCS
40 50 60 70 80 90
240 250 260 270 280
pF1KB8 L--VKEQAFGGL-TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
. .: : : .. .:.::::::.::.:. : :: :::. .:. .::::..: :..
XP_005 RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
:::: ::: ...... ..:.:::. ..:::...::::::::...: ::... :::
XP_005 DYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQV---KSGRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWE
: :. .: ::. :. ..: .:: : : :..:: .::.:: .:. .::
XP_005 TYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWE
220 230 240 250 260 270
410 420
pF1KB8 SMARDRRPLLTAPDHCSDDA
. .. : : : :. :.
XP_005 Q--QEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
280 290 300 310 320
>>XP_005255024 (OMIM: 610177) PREDICTED: apoptosis-enhan (325 aa)
initn: 498 init1: 385 opt: 515 Z-score: 421.1 bits: 86.6 E(85289): 1e-16
Smith-Waterman score: 515; 39.1% identity (67.8% similar) in 230 aa overlap (201-422:65-292)
180 190 200 210 220 230
pF1KB8 RGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLS
:. . :: . :::. ... : . ::. :
XP_005 RQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCS
40 50 60 70 80 90
240 250 260 270 280
pF1KB8 L--VKEQAFGGL-TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
. .: : : .. .:.::::::.::.:. : :: :::. .:. .::::..: :..
XP_005 RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
:::: ::: ...... ..:.:::. ..:::...::::::::...: ::... :::
XP_005 DYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQV---KSGRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWE
: :. .: ::. :. ..: .:: : : :..:: .::.:: .:. .::
XP_005 TYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWE
220 230 240 250 260 270
410 420
pF1KB8 SMARDRRPLLTAPDHCSDDA
. .. : : : :. :.
XP_005 Q--QEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
280 290 300 310 320
>>XP_011520207 (OMIM: 610177) PREDICTED: apoptosis-enhan (325 aa)
initn: 498 init1: 385 opt: 515 Z-score: 421.1 bits: 86.6 E(85289): 1e-16
Smith-Waterman score: 515; 39.1% identity (67.8% similar) in 230 aa overlap (201-422:65-292)
180 190 200 210 220 230
pF1KB8 RGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLS
:. . :: . :::. ... : . ::. :
XP_011 RQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCS
40 50 60 70 80 90
240 250 260 270 280
pF1KB8 L--VKEQAFGGL-TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
. .: : : .. .:.::::::.::.:. : :: :::. .:. .::::..: :..
XP_011 RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
:::: ::: ...... ..:.:::. ..:::...::::::::...: ::... :::
XP_011 DYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQV---KSGRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWE
: :. .: ::. :. ..: .:: : : :..:: .::.:: .:. .::
XP_011 TYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWE
220 230 240 250 260 270
410 420
pF1KB8 SMARDRRPLLTAPDHCSDDA
. .. : : : :. :.
XP_011 Q--QEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
280 290 300 310 320
>>XP_016877978 (OMIM: 610177) PREDICTED: apoptosis-enhan (325 aa)
initn: 498 init1: 385 opt: 515 Z-score: 421.1 bits: 86.6 E(85289): 1e-16
Smith-Waterman score: 515; 39.1% identity (67.8% similar) in 230 aa overlap (201-422:65-292)
180 190 200 210 220 230
pF1KB8 RGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLS
:. . :: . :::. ... : . ::. :
XP_016 RQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCS
40 50 60 70 80 90
240 250 260 270 280
pF1KB8 L--VKEQAFGGL-TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
. .: : : .. .:.::::::.::.:. : :: :::. .:. .::::..: :..
XP_016 RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
:::: ::: ...... ..:.:::. ..:::...::::::::...: ::... :::
XP_016 DYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQV---KSGRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWE
: :. .: ::. :. ..: .:: : : :..:: .::.:: .:. .::
XP_016 TYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWE
220 230 240 250 260 270
410 420
pF1KB8 SMARDRRPLLTAPDHCSDDA
. .. : : : :. :.
XP_016 Q--QEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
280 290 300 310 320
>>NP_001290024 (OMIM: 611930) interferon-stimulated 20 k (353 aa)
initn: 478 init1: 338 opt: 458 Z-score: 375.8 bits: 78.3 E(85289): 3.4e-14
Smith-Waterman score: 481; 31.8% identity (61.1% similar) in 321 aa overlap (98-407:50-349)
70 80 90 100 110 120
pF1KB8 QNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQ-NKKETSPQVKGE-EMPAGKDQ
: ::. .. .:: .: : : . :. .
NP_001 EGNAKHRNFVKKRRLLERRGFLSKKNQPPSKAPKLHSEPSKKGETPTVDGTWKTPSFPKK
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB8 EASRGSVPSGSKMDRRAPVPR-TKASGTEHNKKGTKERTNGDIVPERGDIE-HKKRKAKE
... .: ::. .:..: : : : . . .. ..: :.. :. : :. :.
NP_001 KTAASSNGSGQPLDKKAAVSWLTPAPSKKADSVAAKVDLLGEFQSALPKINSHPTRSQKK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB8 AAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRA
.. .... :. . ..::.. : . : : :
NP_001 SSQKKSSKKN---------------HPQKNAPQNSTQAHSENKCSGASQK------LPRK
140 150 160 170
250 260 270 280 290 300
pF1KB8 L-ALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLK
. :.::::::.::::. : :: :::: : .::.:. : ..:::: :::: ...
NP_001 MVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMV
180 190 200 210 220 230
310 320 330 340 350
pF1KB8 QGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQV---KS
.. ..... .. ..: :.:.::::.:::.:.: :::. :::.. :.. .. ..
NP_001 NATPFKIARGQILKILTGKIVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRKADCPEN
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB8 GRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWES-MARDRRPLLTAPD
. ::. :..:.:. .:: .. : :..::::.:.:: .:. ::: .::.
NP_001 ATMSLKHLTKKLLNRDIQVGKSGHSSVEDAQATMELYKLVEVEWEEHLARNPPTD
300 310 320 330 340 350
420
pF1KB8 HCSDDA
422 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:27:35 2016 done: Mon Nov 7 03:27:37 2016
Total Scan time: 10.080 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]