Result of FASTA (omim) for
pFN21AB7314
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7314, 1079 aa
1>>>pF1KB7314 1079 - 1079 aa - 1079 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6150+/-0.000449; mu= 2.3276+/- 0.028
mean_var=248.7737+/-53.125, 0's: 0 Z-trim(119.0): 159 B-trim: 1076 in 1/54
Lambda= 0.081315
statistics sampled from 32286 (32497) to 32286 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.381), width: 16
Scan time: 14.320
The best scores are: opt bits E(85289)
NP_872601 (OMIM: 400009) histone demethylase UTY i (1079) 7275 867.7 0
NP_872600 (OMIM: 400009) histone demethylase UTY i (1240) 6668 796.5 0
NP_001245192 (OMIM: 400009) histone demethylase UT (1290) 6668 796.5 0
NP_001245196 (OMIM: 400009) histone demethylase UT (1342) 6668 796.5 0
XP_016885558 (OMIM: 400009) PREDICTED: histone dem (1342) 6668 796.5 0
NP_009056 (OMIM: 400009) histone demethylase UTY i (1347) 6668 796.5 0
XP_016885557 (OMIM: 400009) PREDICTED: histone dem (1347) 6668 796.5 0
XP_011529754 (OMIM: 400009) PREDICTED: histone dem (1485) 6668 796.6 0
NP_001278346 (OMIM: 147920,300128,300867) lysine-s (1356) 5577 668.6 6.9e-191
XP_011542274 (OMIM: 147920,300128,300867) PREDICTE (1392) 5577 668.6 7.1e-191
NP_001245194 (OMIM: 400009) histone demethylase UT (1264) 5277 633.3 2.6e-180
XP_011542275 (OMIM: 147920,300128,300867) PREDICTE (1375) 4890 588.0 1.3e-166
XP_011542270 (OMIM: 147920,300128,300867) PREDICTE (1411) 4890 588.0 1.3e-166
XP_011529764 (OMIM: 400009) PREDICTED: histone dem (1154) 4712 567.0 2.2e-160
XP_011529766 (OMIM: 400009) PREDICTED: histone dem (1124) 4687 564.1 1.6e-159
NP_001245188 (OMIM: 400009) histone demethylase UT (1331) 4655 560.4 2.5e-158
XP_011529763 (OMIM: 400009) PREDICTED: histone dem (1176) 4639 558.5 8.3e-158
NP_001245189 (OMIM: 400009) histone demethylase UT (1377) 4189 505.7 7.3e-142
XP_011529752 (OMIM: 400009) PREDICTED: histone dem (1515) 4189 505.8 7.9e-142
NP_001245190 (OMIM: 400009) histone demethylase UT (1389) 4139 499.9 4.3e-140
XP_011529760 (OMIM: 400009) PREDICTED: histone dem (1422) 4105 495.9 6.9e-139
XP_016885555 (OMIM: 400009) PREDICTED: histone dem (1422) 4105 495.9 6.9e-139
XP_005262575 (OMIM: 400009) PREDICTED: histone dem (1182) 4080 492.9 4.6e-138
NP_001278350 (OMIM: 147920,300128,300867) lysine-s (1105) 4079 492.8 4.7e-138
NP_001245185 (OMIM: 400009) histone demethylase UT (1335) 4080 492.9 5e-138
NP_001245195 (OMIM: 400009) histone demethylase UT (1367) 4080 492.9 5.1e-138
XP_016885556 (OMIM: 400009) PREDICTED: histone dem (1387) 4080 492.9 5.2e-138
NP_001245181 (OMIM: 400009) histone demethylase UT (1392) 4080 492.9 5.2e-138
XP_011529751 (OMIM: 400009) PREDICTED: histone dem (1530) 4080 493.0 5.6e-138
NP_001245193 (OMIM: 400009) histone demethylase UT (1376) 4038 488.0 1.6e-136
XP_006724938 (OMIM: 400009) PREDICTED: histone dem (1234) 4032 487.3 2.4e-136
NP_001245187 (OMIM: 400009) histone demethylase UT (1399) 4032 487.3 2.6e-136
NP_001245178 (OMIM: 400009) histone demethylase UT (1444) 4032 487.3 2.7e-136
XP_011529749 (OMIM: 400009) PREDICTED: histone dem (1537) 4032 487.3 2.8e-136
XP_011529744 (OMIM: 400009) PREDICTED: histone dem (1582) 4032 487.4 2.9e-136
XP_016885562 (OMIM: 400009) PREDICTED: histone dem (1063) 3991 482.4 5.9e-135
XP_011529767 (OMIM: 400009) PREDICTED: histone dem (1095) 3991 482.4 6e-135
NP_001245182 (OMIM: 400009) histone demethylase UT (1306) 3991 482.5 6.9e-135
NP_001245180 (OMIM: 400009) histone demethylase UT (1363) 3991 482.5 7.1e-135
XP_011529753 (OMIM: 400009) PREDICTED: histone dem (1501) 3991 482.5 7.7e-135
XP_011529765 (OMIM: 400009) PREDICTED: histone dem (1140) 3364 408.9 8.6e-113
XP_016885561 (OMIM: 400009) PREDICTED: histone dem (1125) 3346 406.8 3.7e-112
XP_011529762 (OMIM: 400009) PREDICTED: histone dem (1192) 3346 406.8 3.8e-112
NP_001245199 (OMIM: 400009) histone demethylase UT (1218) 3149 383.7 3.5e-105
NP_001245186 (OMIM: 400009) histone demethylase UT (1223) 3149 383.7 3.6e-105
XP_016885273 (OMIM: 147920,300128,300867) PREDICTE (1193) 3122 380.5 3.1e-104
XP_011542277 (OMIM: 147920,300128,300867) PREDICTE (1238) 3117 379.9 4.8e-104
XP_016885274 (OMIM: 147920,300128,300867) PREDICTE (1071) 2892 353.5 3.8e-96
NP_001245191 (OMIM: 400009) histone demethylase UT (1320) 2798 342.5 9.4e-93
XP_011529747 (OMIM: 400009) PREDICTED: histone dem (1553) 2765 338.7 1.6e-91
>>NP_872601 (OMIM: 400009) histone demethylase UTY isofo (1079 aa)
initn: 7275 init1: 7275 opt: 7275 Z-score: 4625.9 bits: 867.7 E(85289): 0
Smith-Waterman score: 7275; 100.0% identity (100.0% similar) in 1079 aa overlap (1-1079:1-1079)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
1030 1040 1050 1060 1070
>>NP_872600 (OMIM: 400009) histone demethylase UTY isofo (1240 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4240.2 bits: 796.5 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
NP_872 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
NP_872 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>NP_001245192 (OMIM: 400009) histone demethylase UTY is (1290 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4240.0 bits: 796.5 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
NP_001 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
NP_001 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>NP_001245196 (OMIM: 400009) histone demethylase UTY is (1342 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4239.7 bits: 796.5 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
NP_001 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
NP_001 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>XP_016885558 (OMIM: 400009) PREDICTED: histone demethy (1342 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4239.7 bits: 796.5 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
XP_016 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
XP_016 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>NP_009056 (OMIM: 400009) histone demethylase UTY isofo (1347 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4239.7 bits: 796.5 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
NP_009 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
NP_009 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>XP_016885557 (OMIM: 400009) PREDICTED: histone demethy (1347 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4239.7 bits: 796.5 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
XP_016 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
XP_016 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>XP_011529754 (OMIM: 400009) PREDICTED: histone demethy (1485 aa)
initn: 6668 init1: 6668 opt: 6668 Z-score: 4239.1 bits: 796.6 E(85289): 0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)
10 20 30 40 50 60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
:::::::::::::::::::::::::::::::::::
XP_011 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
XP_011 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
1030 1040 1050 1060 1070 1080
>>NP_001278346 (OMIM: 147920,300128,300867) lysine-speci (1356 aa)
initn: 4193 init1: 2531 opt: 5577 Z-score: 3548.0 bits: 668.6 E(85289): 6.9e-191
Smith-Waterman score: 5577; 84.1% identity (92.8% similar) in 1003 aa overlap (1-995:1-1003)
10 20 30 40 50
pF1KB7 MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
::::.:::.:::.: :::: :::: :::: :::: : :::.::::::::.::::::::
NP_001 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
:.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
:::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
NP_001 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
:::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
NP_001 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
NP_001 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQ-VY
::::::::::::::::::.::: :::::.::::::.::: ::::.::...:: :::: ..
NP_001 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAH
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 SLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHN
: :::::::::::::::::.::::::: .::::::::::::: :: :::::.::: :
NP_001 SWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 GAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKIL
: .::::::::::..::. ::::: ::::::::::: . :..: :::: .::.::. :
NP_001 GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHK
:::::::.:.: :.:: :::::::::.:. :::::.:.:.::.::::..:::::.:::::
NP_001 GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 SQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTAT
.::: .::: :.:: ::: .:. ::...::.. : : ::::::: :: : .::: ::::
NP_001 GQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 SGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHG
::::::: .::::::: : :::::::::.: :. :.:.:: :::::. :::: ::.::
NP_001 SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB7 DS--PNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIST
:: :.:: .:::::::::.::::.::::::::::::::::::::::.::::::::::::
NP_001 DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAIST
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB7 ATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSM
:::::::::: . :::::::::::::::.::::. .::: :.:: :..:. . ::.:::
NP_001 ATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSM
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB7 SVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYL
:::: :::.:::::::: :::::::: ::::::::::::.::::::::::::::::::::
NP_001 SVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB7 ENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 ENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB7 QPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPG
::::::::::::::::.::::::::::::::::::::::::::
NP_001 QPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSES
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB7 FKRFSHLSLPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGIT
NP_001 TSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHT
1030 1040 1050 1060 1070 1080
>>XP_011542274 (OMIM: 147920,300128,300867) PREDICTED: l (1392 aa)
initn: 4193 init1: 2531 opt: 5577 Z-score: 3547.8 bits: 668.6 E(85289): 7.1e-191
Smith-Waterman score: 5577; 84.1% identity (92.8% similar) in 1003 aa overlap (1-995:1-1003)
10 20 30 40 50
pF1KB7 MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
::::.:::.:::.: :::: :::: :::: :::: : :::.::::::::.::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
:.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
:::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
:::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQ-VY
::::::::::::::::::.::: :::::.::::::.::: ::::.::...:: :::: ..
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAH
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 SLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHN
: :::::::::::::::::.::::::: .::::::::::::: :: :::::.::: :
XP_011 SWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 GAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKIL
: .::::::::::..::. ::::: ::::::::::: . :..: :::: .::.::. :
XP_011 GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHK
:::::::.:.: :.:: :::::::::.:. :::::.:.:.::.::::..:::::.:::::
XP_011 GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 SQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTAT
.::: .::: :.:: ::: .:. ::...::.. : : ::::::: :: : .::: ::::
XP_011 GQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 SGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHG
::::::: .::::::: : :::::::::.: :. :.:.:: :::::. :::: ::.::
XP_011 SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB7 DS--PNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIST
:: :.:: .:::::::::.::::.::::::::::::::::::::::.::::::::::::
XP_011 DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAIST
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB7 ATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSM
:::::::::: . :::::::::::::::.::::. .::: :.:: :..:. . ::.:::
XP_011 ATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSM
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB7 SVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYL
:::: :::.:::::::: :::::::: ::::::::::::.::::::::::::::::::::
XP_011 SVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB7 ENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_011 ENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB7 QPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPG
::::::::::::::::.::::::::::::::::::::::::::
XP_011 QPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSES
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB7 FKRFSHLSLPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGIT
XP_011 TSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHT
1030 1040 1050 1060 1070 1080
1079 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:34:38 2016 done: Sat Nov 5 08:34:41 2016
Total Scan time: 14.320 Total Display time: 0.540
Function used was FASTA [36.3.4 Apr, 2011]