Result of FASTA (ccds) for
pFN21AB5459
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5459, 391 aa
1>>>pF1KB5459 391 - 391 aa - 391 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5865+/-0.000812; mu= 9.8949+/- 0.049
mean_var=75.9360+/-15.064, 0's: 0 Z-trim(107.6): 19 B-trim: 0 in 0/51
Lambda= 0.147181
statistics sampled from 9692 (9703) to 9692 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.298), width: 16
Scan time: 2.910
The best scores are: opt bits E(32554)
CCDS72876.1 TXNIP gene_id:10628|Hs108|chr1 ( 391) 2628 567.4 8e-162
CCDS81368.1 TXNIP gene_id:10628|Hs108|chr1 ( 336) 2097 454.6 6e-128
CCDS10377.1 ARRDC4 gene_id:91947|Hs108|chr15 ( 418) 1143 252.1 7.1e-67
CCDS34202.1 ARRDC3 gene_id:57561|Hs108|chr5 ( 414) 946 210.2 2.7e-54
CCDS12370.1 ARRDC2 gene_id:27106|Hs108|chr19 ( 407) 891 198.5 8.8e-51
CCDS32956.1 ARRDC2 gene_id:27106|Hs108|chr19 ( 402) 868 193.7 2.6e-49
>>CCDS72876.1 TXNIP gene_id:10628|Hs108|chr1 (391 aa)
initn: 2628 init1: 2628 opt: 2628 Z-score: 3018.8 bits: 567.4 E(32554): 8e-162
Smith-Waterman score: 2628; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391)
10 20 30 40 50 60
pF1KB5 MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
310 320 330 340 350 360
370 380 390
pF1KB5 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
:::::::::::::::::::::::::::::::
CCDS72 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
370 380 390
>>CCDS81368.1 TXNIP gene_id:10628|Hs108|chr1 (336 aa)
initn: 2097 init1: 2097 opt: 2097 Z-score: 2410.6 bits: 454.6 E(32554): 6e-128
Smith-Waterman score: 2097; 99.7% identity (100.0% similar) in 310 aa overlap (82-391:27-336)
60 70 80 90 100 110
pF1KB5 AKVLWMQGSQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLG
:.::::::::::::::::::::::::::::
CCDS81 MPPKHSLSHRCILSVTASLMATRFSFPSGENEMVIMRPGNKYEYKFGFELPQGPLG
10 20 30 40 50
120 130 140 150 160 170
pF1KB5 TSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCM
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB5 FIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLT
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB5 QKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILD
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB5 LPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPL
240 250 260 270 280 290
360 370 380 390
pF1KB5 LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
::::::::::::::::::::::::::::::::::::::::
CCDS81 LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
300 310 320 330
>>CCDS10377.1 ARRDC4 gene_id:91947|Hs108|chr15 (418 aa)
initn: 986 init1: 717 opt: 1143 Z-score: 1314.1 bits: 252.1 E(32554): 7.1e-67
Smith-Waterman score: 1143; 45.4% identity (72.8% similar) in 394 aa overlap (6-383:16-403)
10 20 30 40
pF1KB5 MVMFKKIKSFEVVFNDPEK-VYGSGEKVAGRVIVEVCEVTRVKAVRILAC
..::. .::.: .: :.::: :::.:..:. : . ..:.:. :
CCDS10 MGGEAGCAAAVGAEGRVKSLGLVFEDERKGCYSSGETVAGHVLLEASEPVALRALRLEAQ
10 20 30 40 50 60
50 60 70 80 90
pF1KB5 GVAKVLWMQGSQQCKQTS------------EYLRYEDTLLLEDQPTGENEMVIMRPGNKY
: : . : : . : ..: ::: . : :.. :.::. .....:: :.
CCDS10 GRATAAW--GPSTCPRASASTAALAVFSEVEYLNVR--LSLREPPAGEG-IILLQPG-KH
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 EYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLM
:. : :.::. :: ::: :::: ..: :.: :.::. : : .:....::. :::::: :.
CCDS10 EFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERPKVPDQSVKRELQVVSHVDVNTPALL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 APVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVA
.:: .:: :.: :. .: ::.::.:.:::.:.:. : :.:..:: ::..::::::
CCDS10 TPVLKTQEKMVGCWFFTSGPVSLSAKIERKGYCNGEAIPIYAEIENCSSRLIVPKAAIFQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 RHTYLANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLL
.::::.:.::.. . ...:::::: ::. .: ::.:.. . :::: : :.::.:::
CCDS10 TQTYLASGKTKTIRHMVANVRGNHIASGSTDTWNGKTLKIPPVTPSILDCCIIRVDYSLA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 IYVSVPGSKKVILDLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYM
.:. .::.::..:.::::::. .:..::.::.::. : .:::. :..:. ::::: :
CCDS10 VYIHIPGAKKLMLELPLVIGTIPYNGFGSRNSSIASQFSMDMSWLTLTLPEQPEAPPNYA
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 DVIPEDHRLES-PTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
::. :.. . : : . .: :.: ::.:.::: :.::::
CCDS10 DVVSEEEFSRHIPPYPQPPNCEGEVCCPVFACIQEFRFQPPPLYSEVDPHPSDVEESQPV
360 370 380 390 400 410
CCDS10 SFIL
>>CCDS34202.1 ARRDC3 gene_id:57561|Hs108|chr5 (414 aa)
initn: 1038 init1: 672 opt: 946 Z-score: 1088.1 bits: 210.2 E(32554): 2.7e-54
Smith-Waterman score: 1049; 42.1% identity (70.8% similar) in 401 aa overlap (2-383:1-399)
10 20 30 40 50
pF1KB5 MVMFKKIKSFEVVF---NDPE-KVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLW
... :.::. . : :: . ::.::. :.::: .:: :::...: : : ::: :
CCDS34 MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRW
10 20 30 40 50
60 70 80 90 100
pF1KB5 MQ----GS-----QQCKQTSEYLRYEDTLL--LEDQPTGENEMVIMRPGNKYEYKFGFEL
. :: :. . ::. ..: :. .:. ..:. . .. : ..:: :.:::
CCDS34 TESRNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNSEEGFHTIHSG-RHEYAFSFEL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 PQGPLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKE
:: ::.:::.:..: : ::::: : :: . ::.: : . .:.:::.:..: .. ::
CCDS34 PQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 KKVSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANG
: . : : .: .:.::.:.:::. :. :.: :..:: ::.::::::: ... :.:
CCDS34 KTLCCWFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 QTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGS
. : . : ....::. . :: .: :: :.. . :::: :.:.::::::..::..::.
CCDS34 KMKEVKQLVANLRGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 KKVILDLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHR
..:.::::::. ..:::::..:. : .:.:..:..:. ::::: : .:. :..:
CCDS34 MDLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQR
300 310 320 330 340 350
350 360 370 380 390
pF1KB5 LESPTTPL--LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
.. .:. ::.. . ..:.: : ::.:.::: :.:.::
CCDS34 -RNNLAPVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSCPSR
360 370 380 390 400 410
>>CCDS12370.1 ARRDC2 gene_id:27106|Hs108|chr19 (407 aa)
initn: 808 init1: 529 opt: 891 Z-score: 1025.1 bits: 198.5 E(32554): 8.8e-51
Smith-Waterman score: 891; 38.8% identity (66.4% similar) in 399 aa overlap (2-383:1-393)
10 20 30 40 50
pF1KB5 MVMFKKIKSFEVVFNDP----EKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLW
..: :.:.: : .. : :...:. :::::..:. ..:: :.:. : : :.: :
CCDS12 MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHW
10 20 30 40 50
60 70 80 90 100
pF1KB5 MQ----GS-----QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQ
. :: :. .. : . .. ::: : :::. . . :: ..:. :.:.::
CCDS12 TESRSAGSSTAYTQSYSERVEVVSHRATLLAPD--TGET--TTLPPG-RHEFLFSFQLPP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 GPLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKK
: :::.::.: : : .:: : :: :.....: : :.. ::.::: :.:: .. .::
CCDS12 -TLVTSFEGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 VSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQT
. . : ::.::.:::::. :. : . :...: .: :.:.::.: .:..: :
CCDS12 ARSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGAR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 KVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKK
: ..:. :. . : : :.:..::. . :::: : .:.:.:.: . :..::..:
CCDS12 KQKRAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 VILDLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIP--EDHR
..:.::::::. ..::.::..:..: ..: .:. ::::: : .:. :.
CCDS12 LLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAA
300 310 320 330 340 350
350 360 370 380 390
pF1KB5 LESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
: . :: .: : : ..:.: : ::.. ::: :.: ::
CCDS12 LGQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC
360 370 380 390 400
>>CCDS32956.1 ARRDC2 gene_id:27106|Hs108|chr19 (402 aa)
initn: 815 init1: 529 opt: 868 Z-score: 998.8 bits: 193.7 E(32554): 2.6e-49
Smith-Waterman score: 868; 38.5% identity (66.4% similar) in 390 aa overlap (7-383:6-388)
10 20 30 40 50
pF1KB5 MVMFKKIKSFEVVFN-DPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG
..:: . . : .: .::.. :::..:. ::.:... : : : . :..:
CCDS32 MRSGGVRSFALELARGPGGAYRGGERLCGRVLLEAAAPLRVRALEVKARGGAATHWLEG
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 --------SQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLG
:.. . ::: .. :::.: :::. . . :: ..:. :.:.:: :
CCDS32 RSVGVNAVSSDYAAAETYLRRRQ-LLLRD--TGET--TTLPPG-RHEFLFSFQLPP-TLV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCM
:::.::.: : : .:: : :: :.....: : :.. ::.::: :.:: .. .:: .
CCDS32 TSFEGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSW
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 FIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLT
. : ::.::.:::::. :. : . :...: .: :.:.::.: .:..: : :
CCDS32 YCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 QKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILD
..:. :. . : : :.:..::. . :::: : .:.:.:.: . :..::..:..:.
CCDS32 AVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLE
240 250 260 270 280 290
300 310 320 330 340
pF1KB5 LPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIP--EDHRLESP
::::::. ..::.::..:..: ..: .:. ::::: : .:. :. : .
CCDS32 LPLVIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQS
300 310 320 330 340 350
350 360 370 380 390
pF1KB5 TTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
:: .: : : ..:.: : ::.. ::: :.: ::
CCDS32 PFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC
360 370 380 390 400
391 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:40:11 2016 done: Fri Nov 4 21:40:12 2016
Total Scan time: 2.910 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]