Result of FASTA (omim) for
pFN21AB7214
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7214, 293 aa
1>>>pF1KB7214 293 - 293 aa - 293 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0190+/-0.000294; mu= 8.4634+/- 0.018
mean_var=115.3393+/-22.637, 0's: 0 Z-trim(120.9): 311 B-trim: 0 in 0/54
Lambda= 0.119422
statistics sampled from 36515 (36835) to 36515 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.432), width: 16
Scan time: 7.700
The best scores are: opt bits E(85289)
NP_659205 (OMIM: 608159) testisin isoform 2 prepro ( 312) 628 118.3 1.9e-26
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343) 607 114.7 2.5e-25
NP_114154 (OMIM: 608018) serine protease 27 isofor ( 290) 600 113.5 5e-25
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 596 112.9 1.1e-24
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 596 112.9 1.1e-24
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 596 113.0 1.6e-24
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 596 113.0 1.6e-24
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 596 113.0 1.6e-24
NP_690851 (OMIM: 613797) serine protease 33 precur ( 280) 577 109.5 7.6e-24
XP_011520754 (OMIM: 613797) PREDICTED: serine prot ( 280) 577 109.5 7.6e-24
XP_011520753 (OMIM: 613797) PREDICTED: serine prot ( 280) 577 109.5 7.6e-24
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 566 107.9 6.8e-23
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 566 107.9 6.9e-23
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 558 106.3 8.2e-23
XP_016878364 (OMIM: 608159) PREDICTED: testisin is ( 298) 555 105.7 1.1e-22
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 549 104.7 2.1e-22
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536) 553 105.5 2.3e-22
XP_006714200 (OMIM: 264900,612416) PREDICTED: coag ( 610) 553 105.6 2.6e-22
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 549 104.7 2.6e-22
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 549 104.7 2.6e-22
NP_000119 (OMIM: 264900,612416) coagulation factor ( 625) 553 105.6 2.6e-22
XP_005262878 (OMIM: 264900,612416) PREDICTED: coag ( 626) 553 105.6 2.6e-22
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 546 104.2 3e-22
NP_940866 (OMIM: 615144) serine protease 55 isofor ( 352) 543 103.7 5.3e-22
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 543 103.7 6.1e-22
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 543 103.8 6.5e-22
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 543 103.8 6.6e-22
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 536 102.5 1.3e-21
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 536 102.6 1.5e-21
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 536 102.6 1.6e-21
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 536 102.6 1.6e-21
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 536 102.6 1.7e-21
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 525 100.6 4.2e-21
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 525 100.6 4.2e-21
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 522 100.0 5.1e-21
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 518 99.4 9e-21
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 521 100.0 1e-20
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 521 100.0 1.1e-20
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 521 100.0 1.1e-20
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 518 99.4 1.2e-20
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 518 99.4 1.2e-20
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 518 99.4 1.3e-20
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 518 99.4 1.3e-20
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 518 99.4 1.3e-20
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 509 97.8 2.9e-20
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 507 97.4 3.1e-20
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 509 97.9 3.8e-20
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 506 97.4 5.5e-20
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456) 506 97.4 5.5e-20
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489) 506 97.4 5.8e-20
>>NP_659205 (OMIM: 608159) testisin isoform 2 preproprot (312 aa)
initn: 576 init1: 387 opt: 628 Z-score: 595.9 bits: 118.3 E(85289): 1.9e-26
Smith-Waterman score: 643; 41.4% identity (62.3% similar) in 268 aa overlap (37-293:12-262)
10 20 30 40 50 60
pF1KB7 SRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSF
::.. : ..::.. : .: .::
NP_659 MGARGALLLALLLARAGLRKPESQEA-APLSGP--------
10 20 30
70 80 90 100 110 120
pF1KB7 PGDSLLCGRTPL--RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISS
::: . ::::: ::: :::::: :.: :.:: .:.. :.:::.::. .
NP_659 ------CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFET
40 50 60 70 80
130 140 150 160 170
pF1KB7 RFH----YSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRN---DLALLQLQHPVN
. . :..:. . . :. . : :: . . . : :.::..:. ::.
NP_659 DLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVT
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB7 FTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLAS-EILQDVDQYIMCYEECNKII
.:..:::::. .:. :.:: ::::::: : : : : . ::.:. :. ::...
NP_659 YTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLF
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB7 QKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
: : :: :. ::: : . :::.: ::::: :::. : : :.:.::::.::::
NP_659 LK-YSFRKD-IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPN
210 220 230 240 250 260
NP_659 RPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPLLGPV
270 280 290 300 310
>>NP_002764 (OMIM: 600823) prostasin preproprotein [Homo (343 aa)
initn: 545 init1: 223 opt: 607 Z-score: 575.7 bits: 114.7 E(85289): 2.5e-25
Smith-Waterman score: 607; 40.8% identity (66.7% similar) in 228 aa overlap (73-292:37-263)
50 60 70 80 90 100
pF1KB7 GENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPL-RIVGGVDAEEGRWPWQVSVRTKG
:: .: ::.:: .: :.::::::. .:
NP_002 LGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG
10 20 30 40 50 60
110 120 130 140 150
pF1KB7 RHICGGTLVTATWVLTAGHCISSRFH---YSVKMGDRSVYNENTSVVVSVQRAFV-HPKF
:.:::.::. :::.:.::. :. : : ::.: ... . . .. ::. . .. ::..
NP_002 VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSY
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB7 STVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKT-PEREKLAS
. ..:.:::::..:..:. :.:::.: : . . .: :::::.. : :.
NP_002 LQEGS-QGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTP
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB7 EILQDVDQYIMCYEECNKIIQ-KALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACE
. ::... .. : :: . . : . . ::: :: : :::.::::::: :.:
NP_002 KPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCP
190 200 210 220 230 240
280 290
pF1KB7 YNDTWVQVGIVSWGIGCGR
. : .:::::: .::
NP_002 VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNL
250 260 270 280 290 300
>>NP_114154 (OMIM: 608018) serine protease 27 isoform 1 (290 aa)
initn: 544 init1: 225 opt: 600 Z-score: 570.3 bits: 113.5 E(85289): 5e-25
Smith-Waterman score: 600; 37.9% identity (66.0% similar) in 253 aa overlap (56-293:5-255)
30 40 50 60 70
pF1KB7 AGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFPGD----SLLCGRTPL--R
:. :: :. : .. . ::: . :
NP_114 MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNR
10 20 30
80 90 100 110 120 130
pF1KB7 IVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCI---SSRFHYSVKMGDRS
.::: :..::.::::::.. .: :.:::.:.. :::::.::. : :.: .: :.
NP_114 MVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 VYNENTSVVVS-VQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVE
. . . .. . :... .: .. ... :.::..:. :: ::. : :.:.:. . :
NP_114 LVQPGPHAMYARVRQVESNPLYQGTAS-SADVALVELEAPVPFTNYILPVCLPDPSVIFE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 GRTRCWVTGWGKTPEREKLASE--ILQDVDQYIMCYEECNKIIQK--ALSSTKDVIIKGM
::::::: .: .: : : ::: . :. .:: . .: .. .: . :
NP_114 TGMNCWVTGWG-SPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDM
160 170 180 190 200 210
260 270 280 290
pF1KB7 VC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
.: :..: ::.:.::::: :.: ...:.:.:..::: ::.:
NP_114 LCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI
220 230 240 250 260 270
NP_114 HRIIPKLQFQPARLGGQK
280 290
>>NP_001305325 (OMIM: 229000,612423) plasma kallikrein i (436 aa)
initn: 497 init1: 204 opt: 596 Z-score: 563.9 bits: 112.9 E(85289): 1.1e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:149-402)
10 20 30 40 50 60
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
:: .:. . : . : .: : : ..
NP_001 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
120 130 140 150 160 170
70 80 90 100 110 120
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
::. .: .: :::::... :.::::::...: ::.:::.:. :::::.::..
NP_001 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
180 190 200 210 220 230
130 140 150 160 170
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
. .: .. : . . .... ..: ... :. .:.::..:: :.:.:
NP_001 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
240 250 260 270 280 290
180 190 200 210 220 230
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
.:::.:... : ::::::: . :. .. ..::: :. .. ::: ::
NP_001 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
300 310 320 330 340
240 250 260 270 280 290
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
.. : : . ::: :::: :::.:.::::: :.:..: : :::.::: ::.:
NP_001 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
350 360 370 380 390 400
NP_001 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
410 420 430
>>XP_016863673 (OMIM: 229000,612423) PREDICTED: plasma k (436 aa)
initn: 497 init1: 204 opt: 596 Z-score: 563.9 bits: 112.9 E(85289): 1.1e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:149-402)
10 20 30 40 50 60
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
:: .:. . : . : .: : : ..
XP_016 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
120 130 140 150 160 170
70 80 90 100 110 120
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
::. .: .: :::::... :.::::::...: ::.:::.:. :::::.::..
XP_016 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
180 190 200 210 220 230
130 140 150 160 170
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
. .: .. : . . .... ..: ... :. .:.::..:: :.:.:
XP_016 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
240 250 260 270 280 290
180 190 200 210 220 230
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
.:::.:... : ::::::: . :. .. ..::: :. .. ::: ::
XP_016 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
300 310 320 330 340
240 250 260 270 280 290
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
.. : : . ::: :::: :::.:.::::: :.:..: : :::.::: ::.:
XP_016 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
350 360 370 380 390 400
XP_016 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
410 420 430
>>NP_000883 (OMIM: 229000,612423) plasma kallikrein isof (638 aa)
initn: 477 init1: 204 opt: 596 Z-score: 561.4 bits: 113.0 E(85289): 1.6e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:351-604)
10 20 30 40 50 60
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
:: .:. . : . : .: : : ..
NP_000 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
330 340 350 360 370
70 80 90 100 110 120
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
::. .: .: :::::... :.::::::...: ::.:::.:. :::::.::..
NP_000 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
380 390 400 410 420 430
130 140 150 160 170
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
. .: .. : . . .... ..: ... :. .:.::..:: :.:.:
NP_000 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
440 450 460 470 480 490
180 190 200 210 220 230
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
.:::.:... : ::::::: . :. .. ..::: :. .. ::: ::
NP_000 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
500 510 520 530 540 550
240 250 260 270 280 290
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
.. : : . ::: :::: :::.:.::::: :.:..: : :::.::: ::.:
NP_000 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
560 570 580 590 600
NP_000 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
610 620 630
>>XP_016863670 (OMIM: 229000,612423) PREDICTED: plasma k (649 aa)
initn: 477 init1: 204 opt: 596 Z-score: 561.3 bits: 113.0 E(85289): 1.6e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:362-615)
10 20 30 40 50 60
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
:: .:. . : . : .: : : ..
XP_016 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
340 350 360 370 380
70 80 90 100 110 120
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
::. .: .: :::::... :.::::::...: ::.:::.:. :::::.::..
XP_016 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
390 400 410 420 430 440
130 140 150 160 170
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
. .: .. : . . .... ..: ... :. .:.::..:: :.:.:
XP_016 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
450 460 470 480 490 500
180 190 200 210 220 230
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
.:::.:... : ::::::: . :. .. ..::: :. .. ::: ::
XP_016 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
510 520 530 540 550 560
240 250 260 270 280 290
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
.. : : . ::: :::: :::.:.::::: :.:..: : :::.::: ::.:
XP_016 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
570 580 590 600 610 620
XP_016 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
630 640
>>XP_011530232 (OMIM: 229000,612423) PREDICTED: plasma k (649 aa)
initn: 477 init1: 204 opt: 596 Z-score: 561.3 bits: 113.0 E(85289): 1.6e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:362-615)
10 20 30 40 50 60
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
:: .:. . : . : .: : : ..
XP_011 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
340 350 360 370 380
70 80 90 100 110 120
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
::. .: .: :::::... :.::::::...: ::.:::.:. :::::.::..
XP_011 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
390 400 410 420 430 440
130 140 150 160 170
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
. .: .. : . . .... ..: ... :. .:.::..:: :.:.:
XP_011 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
450 460 470 480 490 500
180 190 200 210 220 230
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
.:::.:... : ::::::: . :. .. ..::: :. .. ::: ::
XP_011 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
510 520 530 540 550 560
240 250 260 270 280 290
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
.. : : . ::: :::: :::.:.::::: :.:..: : :::.::: ::.:
XP_011 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
570 580 590 600 610 620
XP_011 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
630 640
>>NP_690851 (OMIM: 613797) serine protease 33 precursor (280 aa)
initn: 536 init1: 227 opt: 577 Z-score: 549.1 bits: 109.5 E(85289): 7.6e-24
Smith-Waterman score: 577; 38.4% identity (64.2% similar) in 232 aa overlap (70-291:25-255)
40 50 60 70 80 90
pF1KB7 EEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCG--RTPLRIVGGVDAEEGRWPWQVSV
: :: : ::::: :...:.::::.:.
NP_690 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASI
10 20 30 40 50
100 110 120 130 140 150
pF1KB7 RTKGRHICGGTLVTATWVLTAGHCISSRF---HYSVKMGDRSVYNENT-SVVVSVQRAFV
. .: :.:::.:.. :::::.::. : .: :..: . . . .. : :.:...
NP_690 QHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLL
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB7 HPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREK
: .: :.:::::::..:: ... .::.:.: . . : : :::::.
NP_690 PPDYSE-DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVP
120 130 140 150 160 170
220 230 240 250 260
pF1KB7 LAS-EILQDVDQYIMCYEECNKI--IQKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGG
: . :: : .. . :. . . . ... ... : .: :: . ::.:::::::
NP_690 LPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGG
180 190 200 210 220 230
270 280 290
pF1KB7 RLACEYNDTWVQVGIVSWGIGCGR
:.: . .:: ::.:::: ::
NP_690 PLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
240 250 260 270 280
>>XP_011520754 (OMIM: 613797) PREDICTED: serine protease (280 aa)
initn: 536 init1: 227 opt: 577 Z-score: 549.1 bits: 109.5 E(85289): 7.6e-24
Smith-Waterman score: 577; 38.4% identity (64.2% similar) in 232 aa overlap (70-291:25-255)
40 50 60 70 80 90
pF1KB7 EEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCG--RTPLRIVGGVDAEEGRWPWQVSV
: :: : ::::: :...:.::::.:.
XP_011 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASI
10 20 30 40 50
100 110 120 130 140 150
pF1KB7 RTKGRHICGGTLVTATWVLTAGHCISSRF---HYSVKMGDRSVYNENT-SVVVSVQRAFV
. .: :.:::.:.. :::::.::. : .: :..: . . . .. : :.:...
XP_011 QHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLL
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB7 HPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREK
: .: :.:::::::..:: ... .::.:.: . . : : :::::.
XP_011 PPDYSE-DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVP
120 130 140 150 160 170
220 230 240 250 260
pF1KB7 LAS-EILQDVDQYIMCYEECNKI--IQKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGG
: . :: : .. . :. . . . ... ... : .: :: . ::.:::::::
XP_011 LPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGG
180 190 200 210 220 230
270 280 290
pF1KB7 RLACEYNDTWVQVGIVSWGIGCGR
:.: . .:: ::.:::: ::
XP_011 PLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
240 250 260 270 280
293 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:00:07 2016 done: Sat Nov 5 21:00:08 2016
Total Scan time: 7.700 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]