Result of FASTA (omim) for
pFN21AB6709
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6709, 79 aa
1>>>pF1KB6709 79 - 79 aa - 79 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9337+/-0.000283; mu= 9.1421+/- 0.018
mean_var=55.0524+/-11.089, 0's: 0 Z-trim(118.4): 90 B-trim: 267 in 2/48
Lambda= 0.172857
statistics sampled from 31155 (31253) to 31155 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.366), width: 16
Scan time: 3.960
The best scores are: opt bits E(85289)
NP_003113 (OMIM: 167790,167800,608189) serine prot ( 79) 539 141.6 1.2e-34
NP_066937 (OMIM: 605753) serine protease inhibitor ( 84) 180 52.1 1.1e-07
NP_001258649 (OMIM: 605753) serine protease inhibi ( 119) 174 50.7 4.3e-07
NP_001258647 (OMIM: 605753) serine protease inhibi ( 134) 174 50.7 4.8e-07
NP_995313 (OMIM: 615868) serine protease inhibitor ( 80) 170 49.6 6.2e-07
NP_001182219 (OMIM: 615868) serine protease inhibi ( 80) 170 49.6 6.2e-07
NP_001035523 (OMIM: 613511) serine protease inhibi ( 86) 167 48.9 1.1e-06
XP_011532707 (OMIM: 605753) PREDICTED: serine prot ( 186) 169 49.6 1.5e-06
NP_006837 (OMIM: 147050,256500,605010) serine prot (1064) 162 48.2 2.2e-05
XP_011535853 (OMIM: 147050,256500,605010) PREDICTE (1066) 162 48.2 2.2e-05
NP_001121170 (OMIM: 147050,256500,605010) serine p (1094) 162 48.2 2.3e-05
NP_055286 (OMIM: 613929) serine protease inhibitor ( 86) 147 43.9 3.5e-05
XP_016865198 (OMIM: 613511) PREDICTED: serine prot ( 107) 145 43.5 6e-05
NP_001121171 (OMIM: 147050,256500,605010) serine p ( 916) 155 46.4 6.6e-05
XP_011539731 (OMIM: 103320,615120) PREDICTED: agri (2004) 153 46.1 0.00018
NP_940978 (OMIM: 103320,615120) agrin isoform 2 pr (2045) 153 46.1 0.00019
XP_005244806 (OMIM: 103320,615120) PREDICTED: agri (2049) 153 46.1 0.00019
NP_001292204 (OMIM: 103320,615120) agrin isoform 1 (2068) 153 46.1 0.00019
NP_001035218 (OMIM: 615205) serine protease inhibi ( 94) 136 41.2 0.00025
NP_003683 (OMIM: 603421) tomoregulin-1 precursor [ ( 380) 142 43.0 0.0003
NP_001292074 (OMIM: 605734) tomoregulin-2 isoform ( 175) 138 41.8 0.0003
XP_016859229 (OMIM: 605734) PREDICTED: tomoregulin ( 266) 138 41.9 0.00044
XP_016859228 (OMIM: 605734) PREDICTED: tomoregulin ( 337) 138 42.0 0.00053
NP_001292063 (OMIM: 605734) tomoregulin-2 isoform ( 346) 138 42.0 0.00054
XP_011509192 (OMIM: 605734) PREDICTED: tomoregulin ( 365) 138 42.0 0.00057
NP_057276 (OMIM: 605734) tomoregulin-2 isoform 1 p ( 374) 138 42.0 0.00058
>>NP_003113 (OMIM: 167790,167800,608189) serine protease (79 aa)
initn: 539 init1: 539 opt: 539 Z-score: 742.9 bits: 141.6 E(85289): 1.2e-34
Smith-Waterman score: 539; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79)
10 20 30 40 50 60
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVL
10 20 30 40 50 60
70
pF1KB6 CFENRKRQTSILIQKSGPC
:::::::::::::::::::
NP_003 CFENRKRQTSILIQKSGPC
70
>>NP_066937 (OMIM: 605753) serine protease inhibitor Kaz (84 aa)
initn: 184 init1: 167 opt: 180 Z-score: 258.6 bits: 52.1 E(85289): 1.1e-07
Smith-Waterman score: 180; 38.7% identity (65.3% similar) in 75 aa overlap (6-79:10-84)
10 20 30 40 50
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYDPVCGTDGNTYP
..::.. :: . : : : .: . .: :: . ..::::.: .::
NP_066 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYA
10 20 30 40 50 60
60 70
pF1KB6 NECVLCFENRKRQTSILIQKSGPC
:::.::.. :. .: : ..:::
NP_066 NECTLCMKIREGGHNIKIIRNGPC
70 80
>>NP_001258649 (OMIM: 605753) serine protease inhibitor (119 aa)
initn: 184 init1: 167 opt: 174 Z-score: 248.2 bits: 50.7 E(85289): 4.3e-07
Smith-Waterman score: 174; 41.5% identity (66.2% similar) in 65 aa overlap (16-79:55-119)
10 20 30 40
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYD
:: . : : : .: . .: :: . ..
NP_001 PGERGPPEKSGFGSQTGGGPCPAPGGLGDASLIPQFGLFSKYRTPNCSQYRLPGCPRHFN
30 40 50 60 70 80
50 60 70
pF1KB6 PVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC
::::.: .:: :::.::.. :. .: : ..:::
NP_001 PVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
90 100 110
>>NP_001258647 (OMIM: 605753) serine protease inhibitor (134 aa)
initn: 184 init1: 167 opt: 174 Z-score: 247.4 bits: 50.7 E(85289): 4.8e-07
Smith-Waterman score: 174; 41.5% identity (66.2% similar) in 65 aa overlap (16-79:70-134)
10 20 30 40
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYD
:: . : : : .: . .: :: . ..
NP_001 TGGGPCPAPGGLGDGTRAPVTGGSPEDLPASLIPQFGLFSKYRTPNCSQYRLPGCPRHFN
40 50 60 70 80 90
50 60 70
pF1KB6 PVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC
::::.: .:: :::.::.. :. .: : ..:::
NP_001 PVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
100 110 120 130
>>NP_995313 (OMIM: 615868) serine protease inhibitor Kaz (80 aa)
initn: 166 init1: 108 opt: 170 Z-score: 245.5 bits: 49.6 E(85289): 6.2e-07
Smith-Waterman score: 170; 37.3% identity (65.1% similar) in 83 aa overlap (1-79:1-80)
10 20 30 40 50
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNG----CTKIYDPVCGTDGNTYPN
::..:.::: .:::. . ::. : : .. : .:.. ::. .: ::.::.:: :
NP_995 MKLSGMFLLLSLALFCFL--TGVFSQGGQVDC-GEFQDPKVYCTRESNPHCGSDGQTYGN
10 20 30 40 50
60 70
pF1KB6 ECVLCFENRKRQTSILIQKSGPC
.:..: : .: ... : :
NP_995 KCAFCKAIVKSGGKISLKHPGKC
60 70 80
>>NP_001182219 (OMIM: 615868) serine protease inhibitor (80 aa)
initn: 166 init1: 108 opt: 170 Z-score: 245.5 bits: 49.6 E(85289): 6.2e-07
Smith-Waterman score: 170; 37.3% identity (65.1% similar) in 83 aa overlap (1-79:1-80)
10 20 30 40 50
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNG----CTKIYDPVCGTDGNTYPN
::..:.::: .:::. . ::. : : .. : .:.. ::. .: ::.::.:: :
NP_001 MKLSGMFLLLSLALFCFL--TGVFSQGGQVDC-GEFQDPKVYCTRESNPHCGSDGQTYGN
10 20 30 40 50
60 70
pF1KB6 ECVLCFENRKRQTSILIQKSGPC
.:..: : .: ... : :
NP_001 KCAFCKAIVKSGGKISLKHPGKC
60 70 80
>>NP_001035523 (OMIM: 613511) serine protease inhibitor (86 aa)
initn: 127 init1: 116 opt: 167 Z-score: 241.0 bits: 48.9 E(85289): 1.1e-06
Smith-Waterman score: 167; 32.6% identity (62.8% similar) in 86 aa overlap (1-79:1-86)
10 20 30 40 50
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKC--YNELNG-----CTKIYDPVCGTDGNT
:..:.: :: ::.: .. . : . . . : :..: : ..:::.::.::.:
NP_001 MRATAIVLLLALTLATMFSIECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKT
10 20 30 40 50 60
60 70
pF1KB6 YPNECVLCFENRKRQTSILIQKSGPC
: :.: .: . .: . .. . . : :
NP_001 YKNDCFFCSKVKKTDGTLKFVHFGKC
70 80
>>XP_011532707 (OMIM: 605753) PREDICTED: serine protease (186 aa)
initn: 167 init1: 167 opt: 169 Z-score: 238.5 bits: 49.6 E(85289): 1.5e-06
Smith-Waterman score: 169; 41.8% identity (70.9% similar) in 55 aa overlap (26-79:132-186)
10 20 30 40 50
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYDPVCGTDGNTY
: . .: . .: :: . ..::::.: .::
XP_011 AQVTDRRGKTAGAGGGWRCRCCAWRCCSWQLPSQPNCSQYRLPGCPRHFNPVCGSDMSTY
110 120 130 140 150 160
60 70
pF1KB6 PNECVLCFENRKRQTSILIQKSGPC
:::.::.. :. .: : ..:::
XP_011 ANECTLCMKIREGGHNIKIIRNGPC
170 180
>>NP_006837 (OMIM: 147050,256500,605010) serine protease (1064 aa)
initn: 367 init1: 150 opt: 162 Z-score: 217.5 bits: 48.2 E(85289): 2.2e-05
Smith-Waterman score: 162; 53.7% identity (68.3% similar) in 41 aa overlap (39-79:1006-1046)
10 20 30 40 50 60
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
: : :::: ::.:: : :.:: :: ::
NP_006 SQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQ
980 990 1000 1010 1020 1030
70
pF1KB6 TSILIQKSGPC
:. :...: :
NP_006 TNTHIRSTGKCEESSTPGTTAASMPPSDE
1040 1050 1060
>--
initn: 231 init1: 136 opt: 155 Z-score: 208.1 bits: 46.4 E(85289): 7.5e-05
Smith-Waterman score: 155; 48.8% identity (70.7% similar) in 41 aa overlap (39-79:111-151)
10 20 30 40 50 60
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
: :. ::::::.:: :.:.:: :: :
NP_006 RHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTG
90 100 110 120 130 140
70
pF1KB6 TSILIQKSGPC
..: ... : :
NP_006 SQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAEL
150 160 170 180 190 200
>>XP_011535853 (OMIM: 147050,256500,605010) PREDICTED: s (1066 aa)
initn: 367 init1: 150 opt: 162 Z-score: 217.5 bits: 48.2 E(85289): 2.2e-05
Smith-Waterman score: 162; 53.7% identity (68.3% similar) in 41 aa overlap (39-79:1008-1048)
10 20 30 40 50 60
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
: : :::: ::.:: : :.:: :: ::
XP_011 SQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQ
980 990 1000 1010 1020 1030
70
pF1KB6 TSILIQKSGPC
:. :...: :
XP_011 TNTHIRSTGKCEESSTPGTTAASMPPSDE
1040 1050 1060
>--
initn: 231 init1: 136 opt: 155 Z-score: 208.1 bits: 46.4 E(85289): 7.5e-05
Smith-Waterman score: 155; 48.8% identity (70.7% similar) in 41 aa overlap (39-79:83-123)
10 20 30 40 50 60
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
: :. ::::::.:: :.:.:: :: :
XP_011 RHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTG
60 70 80 90 100 110
70
pF1KB6 TSILIQKSGPC
..: ... : :
XP_011 SQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAEL
120 130 140 150 160 170
79 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:30:03 2016 done: Fri Nov 4 23:30:04 2016
Total Scan time: 3.960 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]