Result of FASTA (omim) for
pFN21AE0450
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0450, 448 aa
1>>>pF1KE0450 448 - 448 aa - 448 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2058+/-0.000368; mu= 19.2406+/- 0.023
mean_var=85.5188+/-18.204, 0's: 0 Z-trim(114.4): 22 B-trim: 1175 in 1/50
Lambda= 0.138689
statistics sampled from 24285 (24303) to 24285 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.285), width: 16
Scan time: 9.470
The best scores are: opt bits E(85289)
NP_001135863 (OMIM: 312090) P3 protein isoform 2 p ( 448) 2871 584.5 1.9e-166
XP_006724911 (OMIM: 312090) PREDICTED: P3 protein ( 541) 2871 584.6 2.2e-166
XP_011529503 (OMIM: 312090) PREDICTED: P3 protein ( 477) 2083 426.9 5.8e-119
NP_001135864 (OMIM: 312090) P3 protein isoform 1 p ( 477) 2083 426.9 5.8e-119
NP_062822 (OMIM: 312090) P3 protein isoform 1 prec ( 477) 2083 426.9 5.8e-119
XP_005277970 (OMIM: 312090) PREDICTED: P3 protein ( 532) 2083 426.9 6.3e-119
XP_011529502 (OMIM: 312090) PREDICTED: P3 protein ( 532) 2083 426.9 6.3e-119
XP_006724910 (OMIM: 312090) PREDICTED: P3 protein ( 570) 2083 426.9 6.6e-119
NP_932069 (OMIM: 613366) solute carrier family 10 ( 377) 452 100.4 8.5e-21
NP_003040 (OMIM: 182396) sodium/bile acid cotransp ( 349) 438 97.6 5.6e-20
NP_000443 (OMIM: 601295,613291) ileal sodium/bile ( 348) 434 96.8 9.7e-20
>>NP_001135863 (OMIM: 312090) P3 protein isoform 2 precu (448 aa)
initn: 2871 init1: 2871 opt: 2871 Z-score: 3109.2 bits: 584.5 E(85289): 1.9e-166
Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)
10 20 30 40 50 60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 IAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAP
370 380 390 400 410 420
430 440
pF1KE0 FIVALSGTSEMLALVIGHFIYSSLFPVP
::::::::::::::::::::::::::::
NP_001 FIVALSGTSEMLALVIGHFIYSSLFPVP
430 440
>>XP_006724911 (OMIM: 312090) PREDICTED: P3 protein isof (541 aa)
initn: 2871 init1: 2871 opt: 2871 Z-score: 3108.1 bits: 584.6 E(85289): 2.2e-166
Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:94-541)
10 20 30
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
::::::::::::::::::::::::::::::
XP_006 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QYPGQANRTAPGPMLRVTSLDTEVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPAT
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE0 LSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPL
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE0 YAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFL
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE0 PLSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFS
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE0 FVLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FVLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSI
430 440 450 460 470 480
400 410 420 430 440
pF1KE0 EVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
490 500 510 520 530 540
>>XP_011529503 (OMIM: 312090) PREDICTED: P3 protein isof (477 aa)
initn: 2083 init1: 2083 opt: 2083 Z-score: 2256.7 bits: 426.9 E(85289): 5.8e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:1-477)
10 20 30 40 50 60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKN-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
70 80 90 100 110 120
120 130 140 150
pF1KE0 ----------------------------LVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
::::::::::::::::::::::::::::::::
XP_011 SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
370 380 390 400 410 420
400 410 420 430 440
pF1KE0 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
430 440 450 460 470
>>NP_001135864 (OMIM: 312090) P3 protein isoform 1 precu (477 aa)
initn: 2083 init1: 2083 opt: 2083 Z-score: 2256.7 bits: 426.9 E(85289): 5.8e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:1-477)
10 20 30 40 50 60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKN-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
70 80 90 100 110 120
120 130 140 150
pF1KE0 ----------------------------LVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
::::::::::::::::::::::::::::::::
NP_001 SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
370 380 390 400 410 420
400 410 420 430 440
pF1KE0 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
430 440 450 460 470
>>NP_062822 (OMIM: 312090) P3 protein isoform 1 precurso (477 aa)
initn: 2083 init1: 2083 opt: 2083 Z-score: 2256.7 bits: 426.9 E(85289): 5.8e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:1-477)
10 20 30 40 50 60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKN-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
70 80 90 100 110 120
120 130 140 150
pF1KE0 ----------------------------LVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
::::::::::::::::::::::::::::::::
NP_062 SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
370 380 390 400 410 420
400 410 420 430 440
pF1KE0 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
430 440 450 460 470
>>XP_005277970 (OMIM: 312090) PREDICTED: P3 protein isof (532 aa)
initn: 2083 init1: 2083 opt: 2083 Z-score: 2256.1 bits: 426.9 E(85289): 6.3e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:56-532)
10 20 30
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
::::::::::::::::::::::::::::::
XP_005 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
90 100 110 120 130 140
100 110 120
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKN-----------------------------LV
::::::::::::::::::::::::::::: ::
XP_005 QYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSIHSGLAGLAPLHIQLV
150 160 170 180 190 200
130 140 150 160 170 180
pF1KE0 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
210 220 230 240 250 260
190 200 210 220 230 240
pF1KE0 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE0 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
390 400 410 420 430 440
370 380 390 400 410 420
pF1KE0 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
450 460 470 480 490 500
430 440
pF1KE0 IVALSGTSEMLALVIGHFIYSSLFPVP
:::::::::::::::::::::::::::
XP_005 IVALSGTSEMLALVIGHFIYSSLFPVP
510 520 530
>>XP_011529502 (OMIM: 312090) PREDICTED: P3 protein isof (532 aa)
initn: 2083 init1: 2083 opt: 2083 Z-score: 2256.1 bits: 426.9 E(85289): 6.3e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:56-532)
10 20 30
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
::::::::::::::::::::::::::::::
XP_011 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
90 100 110 120 130 140
100 110 120
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKN-----------------------------LV
::::::::::::::::::::::::::::: ::
XP_011 QYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSIHSGLAGLAPLHIQLV
150 160 170 180 190 200
130 140 150 160 170 180
pF1KE0 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
210 220 230 240 250 260
190 200 210 220 230 240
pF1KE0 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE0 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
390 400 410 420 430 440
370 380 390 400 410 420
pF1KE0 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
450 460 470 480 490 500
430 440
pF1KE0 IVALSGTSEMLALVIGHFIYSSLFPVP
:::::::::::::::::::::::::::
XP_011 IVALSGTSEMLALVIGHFIYSSLFPVP
510 520 530
>>XP_006724910 (OMIM: 312090) PREDICTED: P3 protein isof (570 aa)
initn: 2083 init1: 2083 opt: 2083 Z-score: 2255.7 bits: 426.9 E(85289): 6.6e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:94-570)
10 20 30
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
::::::::::::::::::::::::::::::
XP_006 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
130 140 150 160 170 180
100 110 120
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKN-----------------------------LV
::::::::::::::::::::::::::::: ::
XP_006 QYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSIHSGLAGLAPLHIQLV
190 200 210 220 230 240
130 140 150 160 170 180
pF1KE0 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
250 260 270 280 290 300
190 200 210 220 230 240
pF1KE0 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
310 320 330 340 350 360
250 260 270 280 290 300
pF1KE0 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
370 380 390 400 410 420
310 320 330 340 350 360
pF1KE0 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
430 440 450 460 470 480
370 380 390 400 410 420
pF1KE0 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
490 500 510 520 530 540
430 440
pF1KE0 IVALSGTSEMLALVIGHFIYSSLFPVP
:::::::::::::::::::::::::::
XP_006 IVALSGTSEMLALVIGHFIYSSLFPVP
550 560 570
>>NP_932069 (OMIM: 613366) solute carrier family 10 memb (377 aa)
initn: 454 init1: 357 opt: 452 Z-score: 494.4 bits: 100.4 E(85289): 8.5e-21
Smith-Waterman score: 452; 31.7% identity (63.5% similar) in 271 aa overlap (143-408:12-278)
120 130 140 150 160 170
pF1KE0 EVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIF
::... : . : .. ... .. ..
NP_932 MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVM
10 20 30 40
180 190 200 210 220 230
pF1KE0 VN--KCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLI
.. :.::.::.. : . .. : . .::: :: .::. :.:.: : : . :....
NP_932 MGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVL
50 60 70 80 90 100
240 250 260 270 280 290
pF1KE0 ITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVP
: ::: : .:.. . ::. :.:::: ::::: :..:: .:. :....: .:
NP_932 IMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIP
110 120 130 140 150 160
300 310 320 330 340 350
pF1KE0 ISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILA
..: ::. ..::.: :: .. . :: :...:.. . :::: .. :: .
NP_932 YQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLL----VVAVAGVVLAK
170 180 190 200 210
360 370 380 390 400
pF1KE0 GI---RLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLS
: . .. ... ::.: ..:. :: . . ::.:.:.:.:: . ..:::::
NP_932 GSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLS
220 230 240 250 260 270
410 420 430 440
pF1KE0 LRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
.
NP_932 FTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTS
280 290 300 310 320 330
>>NP_003040 (OMIM: 182396) sodium/bile acid cotransporte (349 aa)
initn: 409 init1: 271 opt: 438 Z-score: 479.7 bits: 97.6 E(85289): 5.6e-20
Smith-Waterman score: 438; 33.1% identity (65.7% similar) in 248 aa overlap (166-408:30-274)
140 150 160 170 180 190
pF1KE0 DFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQ
.:. ..: :.:: .:. .:. . .:.
NP_003 MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPK
10 20 30 40 50
200 210 220 230 240 250
pF1KE0 PMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLA
. ..:..:. .::: ::...::: : . ::.... ::::. : .::: . ::..:.
NP_003 GLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLS
60 70 80 90 100 110
260 270 280 290 300 310
pF1KE0 ISMTFLSTVAATGFLPLSSAIYSRLLSIHETL-HVPISKILGTLLFIAIPIAVGVLIKSK
: :: :: : :..:: :::: . . .:: . :. .:... :: ..:...:::
NP_003 IVMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSK
120 130 140 150 160 170
320 330 340 350 360 370
pF1KE0 LPKFSQLLLQVVKPFSFVLLLGGLFL----AYRMGVFILAGIRLPIVLVGITVPLVGLLV
: : . :.: ...:: .. . : .: :. .. .. .. .:..:.:.
NP_003 RP---QYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLL
180 190 200 210 220 230
380 390 400 410 420 430
pF1KE0 GYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSE
:: :.. . : :::::.:.: :: : ..:....
NP_003 GYVLSALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGE
240 250 260 270 280 290
440
pF1KE0 MLALVIGHFIYSSLFPVP
NP_003 GLLLIAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA
300 310 320 330 340
448 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:11:15 2016 done: Thu Nov 3 08:11:17 2016
Total Scan time: 9.470 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]