Result of FASTA (ccds) for
pFN21AB8903
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8903, 235 aa
1>>>pF1KB8903 235 - 235 aa - 235 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4777+/-0.000707; mu= 14.2573+/- 0.043
mean_var=86.3327+/-17.726, 0's: 0 Z-trim(110.3): 173 B-trim: 603 in 1/53
Lambda= 0.138034
statistics sampled from 11321 (11524) to 11321 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.354), width: 16
Scan time: 1.650
The best scores are: opt bits E(32554)
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 1580 323.9 5.5e-89
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 1023 212.9 9.8e-56
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 632 135.1 3.6e-32
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 513 111.4 5e-25
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 467 102.3 3.2e-22
CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 ( 230) 443 97.5 7.8e-21
CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 ( 217) 433 95.5 3e-20
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 431 95.2 4.6e-20
CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 ( 242) 417 92.3 3e-19
CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 ( 222) 413 91.5 4.8e-19
CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 ( 264) 407 90.4 1.3e-18
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 398 88.6 4.2e-18
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 394 87.8 7.3e-18
CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 ( 243) 392 87.4 9.3e-18
CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 ( 320) 388 86.7 2e-17
CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 ( 290) 369 82.8 2.6e-16
CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 ( 106) 361 80.9 3.6e-16
CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 ( 289) 363 81.7 5.8e-16
CCDS82153.1 HOXB3 gene_id:3213|Hs108|chr17 ( 299) 300 69.1 3.6e-12
CCDS5404.1 HOXA3 gene_id:3200|Hs108|chr7 ( 443) 302 69.7 3.7e-12
CCDS82154.1 HOXB3 gene_id:3213|Hs108|chr17 ( 358) 300 69.2 4.1e-12
CCDS9327.1 PDX1 gene_id:3651|Hs108|chr13 ( 283) 298 68.7 4.5e-12
CCDS11528.1 HOXB3 gene_id:3213|Hs108|chr17 ( 431) 300 69.2 4.7e-12
CCDS5403.1 HOXA2 gene_id:3199|Hs108|chr7 ( 376) 297 68.6 6.4e-12
CCDS4304.1 CDX1 gene_id:1044|Hs108|chr5 ( 265) 282 65.5 3.9e-11
CCDS2270.1 HOXD3 gene_id:3232|Hs108|chr2 ( 432) 284 66.1 4.3e-11
CCDS34788.1 MNX1 gene_id:3110|Hs108|chr7 ( 401) 281 65.4 6.1e-11
CCDS5401.1 HOXA1 gene_id:3198|Hs108|chr7 ( 335) 280 65.2 6.2e-11
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 ( 352) 279 65.0 7.3e-11
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 1580 init1: 1580 opt: 1580 Z-score: 1711.0 bits: 323.9 E(32554): 5.5e-89
Smith-Waterman score: 1580; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KB8 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 VVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKASI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 QIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 QIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCL
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 TERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 TERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
190 200 210 220 230
>>CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 (153 aa)
initn: 1023 init1: 1023 opt: 1023 Z-score: 1114.1 bits: 212.9 E(32554): 9.8e-56
Smith-Waterman score: 1023; 100.0% identity (100.0% similar) in 153 aa overlap (83-235:1-153)
60 70 80 90 100 110
pF1KB8 PFYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTA
::::::::::::::::::::::::::::::
CCDS41 MLSNCRQNTLGHNTQTSIAQDFSSEQGRTA
10 20 30
120 130 140 150 160 170
pF1KB8 PQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 PQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 EIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEK
100 110 120 130 140 150
pF1KB8 QKE
:::
CCDS41 QKE
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 596 init1: 486 opt: 632 Z-score: 691.0 bits: 135.1 E(32554): 3.6e-32
Smith-Waterman score: 635; 48.3% identity (72.7% similar) in 238 aa overlap (1-229:1-224)
10 20 30 40 50
pF1KB8 MNSYFTNPSLSCHLAGGQD-VLPNVALNSTAY-DPVRHF-STYGAAVAQNRIYSTPFYSP
:.:::.: .. ::.::. : .. : :..: ::.::. . :: . .:.. ..: : :
CCDS11 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QENVVFSSSRGPYDYG-SNSFYQEKD---MLSNCRQNTLGHNT--QTSIAQDFSSEQGRT
. .. . .: ::: . .::.::. ::. .. : ... ::: .: :.:
CCDS11 PAGGGYGRA-APCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQD-KSVFGET
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 APQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRR
..:: : .::::::::: .. ..: . ::::: :.::::::::::::.:::::::::
CCDS11 --EEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 IEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEE
::::.::::::::::::::::::::::::.: : :..:...::.....:
CCDS11 IEIAHALCLTERQIKIWFQNRRMKWKKESKLLS----------ASQLSAEEEEEKQAE
180 190 200 210 220
pF1KB8 KQKE
>>CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 (233 aa)
initn: 714 init1: 488 opt: 513 Z-score: 562.7 bits: 111.4 E(32554): 5e-25
Smith-Waterman score: 696; 49.8% identity (71.2% similar) in 229 aa overlap (1-215:1-229)
10 20 30 40 50
pF1KB8 MNSYFTNPSLSCHLAGGQD-VLPNVALNSTAYDPVRHF-STYGAAVAQNRIYSTPFYSPQ
:.:::.::.. : .::: : .. : ...:: .: : ..:::. .. :..: . :
CCDS54 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ
10 20 30 40 50 60
60 70 80 90 100
pF1KB8 ENVVFSSSRGPYDYGSNSFYQEKDMLSNC-----RQNTLGHNTQTSIAQ----DFSSEQG
: :.. .:. :.::.. ::..::. . .: : . : : : :: ::
CCDS54 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 RTAPQ---DQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYL
.. . :.: . .::::::::: .:. ::. ::::: :.:::::::::::::::::
CCDS54 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKRE
:::::::::::::::::::::::::::::::::..: .. . .: . :
CCDS54 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
190 200 210 220 230
230
pF1KB8 ETEEEKQKE
>>CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 (270 aa)
initn: 455 init1: 430 opt: 467 Z-score: 512.4 bits: 102.3 E(32554): 3.2e-22
Smith-Waterman score: 486; 47.4% identity (68.9% similar) in 196 aa overlap (38-213:75-267)
10 20 30 40 50 60
pF1KB8 PSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTP---FYSPQENVVFS
.. .:: :. : :: : .::: . .
CCDS54 YGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPR-YSQPATSTHSPQPDPLPC
50 60 70 80 90 100
70 80 90 100
pF1KB8 SSRGPYDYGSNSFYQEKDMLSNCRQNTL-----------GHNTQTSIAQDF--SSEQG--
:. .: . ::.: . :. ::: . : .: .. .: ::::.
CCDS54 SAVAP-SPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASA
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB8 RTAPQDQK-ASIQIYPWMQRMN-SHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLT
.. :. :. ::::::.... ::...: : . .:.: :.::::::::::::::::::
CCDS54 QSEPSPAPPAQPQIYPWMRKLHISHDNIG-GPEGKRARTAYTRYQTLELEKEFHFNRYLT
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB8 RRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREE
::::::::.::::.:::::::::::::::::...: : ...:::
CCDS54 RRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
230 240 250 260 270
230
pF1KB8 TEEEKQKE
>>CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 (230 aa)
initn: 480 init1: 398 opt: 443 Z-score: 487.5 bits: 97.5 E(32554): 7.8e-21
Smith-Waterman score: 478; 39.2% identity (65.4% similar) in 240 aa overlap (2-235:3-229)
10 20 30 40 50
pF1KB8 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTP-FYSPQ
.::..: .: . ::.. .. :. .: .. : . : :::. : ..: .:. .
CCDS54 MSSSYYVNALFSKYTAGAS-LFQNAEPTSCSFAPNSQRSGYGAG-AGAFASTVPGLYNVN
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 ENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKA
. : . : :.... . .. :: : .. . . ....: . .:
CCDS54 SPLYQSPFASGYGLGADAYGNLP--CASYDQNIPGLCSDLAKGACDKTDEG-ALHGAAEA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 SIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANAL
...:::::. . : ::.:::: :.::::::::::::::::::::::::::.::
CCDS54 NFRIYPWMR--------SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHAL
120 130 140 150 160
180 190 200 210 220 230
pF1KB8 CLTERQIKIWFQNRRMKWKKESNLTSTLS-----GGGGGATADSLGGKEEKREETEEEKQ
::::::::::::::::::::: . . . :. .:.: . . : ..... :::..
CCDS54 CLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEED
170 180 190 200 210 220
pF1KB8 KE
.:
CCDS54 EEE
230
>>CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 (217 aa)
initn: 415 init1: 383 opt: 433 Z-score: 477.1 bits: 95.5 E(32554): 3e-20
Smith-Waterman score: 450; 42.0% identity (63.2% similar) in 231 aa overlap (2-227:8-217)
10 20 30 40 50
pF1KB8 MNSYFTN-PSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTP
:. :.. :. : .: : ..:. . . : .: : :::. . . :
CCDS11 MSSLYYANTLFSKYPASSSVFATG--AFPEQTSCAFASNPQR--PGYGAGSGASFAASMQ
10 20 30 40 50
60 70 80 90 100
pF1KB8 -FYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNC---RQNTLGHNTQTSIAQDFSSEQG
.: ... .:. : : : . . .: .: .:: : : ..::
CCDS11 GLYPGGGGMAGQSAAGVYAAGYGLEPSSFNM--HCAPFEQNLSGVCPGDSAKAAGAKEQ-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 RTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRR
: . .....:::::. . :.::.:::: :.::::::::::::.:::::::
CCDS11 RDSDLAAESNFRIYPWMR--------SSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRR
120 130 140 150 160
170 180 190 200 210 220
pF1KB8 RRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETE
::::::..:::::::::::::::::::::: : :. : :.:... . ::..::
CCDS11 RRIEIAHTLCLTERQIKIWFQNRRMKWKKE-NKTA-----GPGTTGQDRAEAEEEEEE
170 180 190 200 210
230
pF1KB8 EEKQKE
>>CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 (269 aa)
initn: 399 init1: 338 opt: 431 Z-score: 473.6 bits: 95.2 E(32554): 4.6e-20
Smith-Waterman score: 431; 59.6% identity (78.9% similar) in 114 aa overlap (101-213:157-266)
80 90 100 110 120 130
pF1KB8 DYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKASIQIYPWMQRMN
:: . .::. : . ::.:::....
CCDS11 SANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQ--TPQIFPWMRKLH
130 140 150 160 170 180
140 150 160 170 180
pF1KB8 -SHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF
::. .: : .:.: :.::::::::::::::::::::::::::.::::.::::::::
CCDS11 ISHDMTG--PDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWF
190 200 210 220 230 240
190 200 210 220 230
pF1KB8 QNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
:::::::::...: : . .:.:
CCDS11 QNRRMKWKKDNKLKSMSLATAGSAFQP
250 260
>>CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 (242 aa)
initn: 487 init1: 359 opt: 417 Z-score: 459.2 bits: 92.3 E(32554): 3e-19
Smith-Waterman score: 431; 37.2% identity (57.9% similar) in 261 aa overlap (1-235:1-242)
10 20 30 40 50 60
pF1KB8 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQEN
:.:::.:: .: . :: ... : :: : .. : . : .:. .: .
CCDS88 MSSYFVNPLFSKYKAG-ESLEP-------AYYDCRFPQSVGRSHAL--VYGPGGSAPGFQ
10 20 30 40 50
70 80 90 100
pF1KB8 VVFSSSRGPYDYG----SNSFYQEKDMLSNC--------------RQNTLGHNTQTSIAQ
. . . .: ::: ::.. .: ::. : . ..:..:
CCDS88 HASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQ
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 --DFSSEQGRTAPQDQKASIQ------IYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTL
: .: . .. . : : ..:::. :. :: ::: :::::::
CCDS88 YPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMR---PHA-----PGRRSGRQTYSRYQTL
120 130 140 150 160
160 170 180 190 200 210
pF1KB8 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGAT
:::::: :: ::::.::::...:: :::::.::::::::::::::.: . : :.
CCDS88 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENN-KDKLPGARDEEK
170 180 190 200 210 220
220 230
pF1KB8 ADSLGGKEEKREETEEEKQKE
.. :..::..:: :.:..:.
CCDS88 VEEEGNEEEEKEEEEKEENKD
230 240
>>CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 (222 aa)
initn: 424 init1: 338 opt: 413 Z-score: 455.4 bits: 91.5 E(32554): 4.8e-19
Smith-Waterman score: 413; 61.9% identity (79.0% similar) in 105 aa overlap (102-204:119-218)
80 90 100 110 120 130
pF1KB8 YGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQK-ASIQIYPWMQRMN
.. ... :. : .: : :::::: ...
CCDS88 DEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLH
90 100 110 120 130 140
140 150 160 170 180
pF1KB8 -SHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF
:: .: .:.: :.::::::::::::::::::::::::::: :::.::::::::
CCDS88 MSHE-----TDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWF
150 160 170 180 190 200
190 200 210 220 230
pF1KB8 QNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
:::::::::.:.. :
CCDS88 QNRRMKWKKDSKMKSKEAL
210 220
235 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:04:27 2016 done: Sat Nov 5 20:04:27 2016
Total Scan time: 1.650 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]