Result of FASTA (ccds) for
pFN21AB6470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6470, 354 aa
1>>>pF1KB6470 354 - 354 aa - 354 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0469+/-0.000869; mu= 12.2956+/- 0.052
mean_var=74.1299+/-14.772, 0's: 0 Z-trim(106.5): 35 B-trim: 54 in 1/50
Lambda= 0.148963
statistics sampled from 9017 (9045) to 9017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.278), width: 16
Scan time: 2.670
The best scores are: opt bits E(32554)
CCDS5568.1 RFC2 gene_id:5982|Hs108|chr7 ( 354) 2320 507.9 5.1e-144
CCDS75618.1 RFC2 gene_id:5982|Hs108|chr7 ( 251) 1594 351.9 3.5e-97
CCDS5567.1 RFC2 gene_id:5982|Hs108|chr7 ( 320) 1383 306.5 1.9e-83
CCDS9185.1 RFC5 gene_id:5985|Hs108|chr12 ( 340) 740 168.4 8.1e-42
CCDS41843.2 RFC5 gene_id:5985|Hs108|chr12 ( 319) 706 161.1 1.2e-39
CCDS3283.1 RFC4 gene_id:5984|Hs108|chr3 ( 363) 673 154.0 1.9e-37
>>CCDS5568.1 RFC2 gene_id:5982|Hs108|chr7 (354 aa)
initn: 2320 init1: 2320 opt: 2320 Z-score: 2699.1 bits: 507.9 E(32554): 5.1e-144
Smith-Waterman score: 2320; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB6 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
310 320 330 340 350
>>CCDS75618.1 RFC2 gene_id:5982|Hs108|chr7 (251 aa)
initn: 1594 init1: 1594 opt: 1594 Z-score: 1858.3 bits: 351.9 E(32554): 3.5e-97
Smith-Waterman score: 1594; 99.2% identity (99.6% similar) in 247 aa overlap (108-354:5-251)
80 90 100 110 120 130
pF1KB6 PGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKI
:. :::::::::::::::::::::::::::
CCDS75 MCPTSSLRGIDVVRNKIKMFAQQKVTLPKGRHKI
10 20 30
140 150 160 170 180 190
pF1KB6 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 PHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFI
160 170 180 190 200 210
320 330 340 350
pF1KB6 KEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
:::::::::::::::::::::::::::::::::::::
CCDS75 KEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
220 230 240 250
>>CCDS5567.1 RFC2 gene_id:5982|Hs108|chr7 (320 aa)
initn: 1382 init1: 1382 opt: 1383 Z-score: 1611.5 bits: 306.5 E(32554): 1.9e-83
Smith-Waterman score: 2024; 90.4% identity (90.4% similar) in 354 aa overlap (1-354:1-320)
10 20 30 40 50 60
pF1KB6 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND----------
70 80 90 100 110
130 140 150 160 170 180
pF1KB6 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
::::::::::::::::::::::::::::::::::::
CCDS55 ------------------------SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
120 130 140
190 200 210 220 230 240
pF1KB6 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB6 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
210 220 230 240 250 260
310 320 330 340 350
pF1KB6 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
270 280 290 300 310 320
>>CCDS9185.1 RFC5 gene_id:5985|Hs108|chr12 (340 aa)
initn: 678 init1: 573 opt: 740 Z-score: 864.2 bits: 168.4 E(32554): 8.1e-42
Smith-Waterman score: 740; 37.2% identity (70.7% similar) in 317 aa overlap (28-342:12-327)
10 20 30 40 50 60
pF1KB6 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
:... .::::::::: ::......: .: .
CCDS91 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTI
10 20 30 40
70 80 90 100 110
pF1KB6 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAM-LELNASNDRGIDVVRNK
. : : .:.... ::::::::..:: :. : .: ::::::.:::::..:.
CCDS91 QKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 IKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE
: ::. .. . :: :..::::::.::. ::.::::..: ....::: : :: .:::
CCDS91 ILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQST
.::::. .:. :: .. :: .:.:.:.: ..::..:.. ..::::.::: ::::
CCDS91 ALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQST
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 FSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHL-GYSPEDIIGN
.:: .. :.:. .: . .... .: .. ::. ...: : : . .::. .
CCDS91 NMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 IFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
: . .. ...... ... ..... :.: .:...:.:
CCDS91 IHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA
290 300 310 320 330 340
>>CCDS41843.2 RFC5 gene_id:5985|Hs108|chr12 (319 aa)
initn: 648 init1: 543 opt: 706 Z-score: 825.2 bits: 161.1 E(32554): 1.2e-39
Smith-Waterman score: 706; 37.3% identity (70.6% similar) in 306 aa overlap (39-342:2-306)
10 20 30 40 50 60
pF1KB6 GAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGN
:::::: ::......: .: .. : :
CCDS41 MVEKYRPQTLNDLISHQDILSTIQKFINEDR
10 20 30
70 80 90 100 110 120
pF1KB6 VPNIIIAGPPGTGKTTSILCLARALLGPALKDAM-LELNASNDRGIDVVRNKIKMFAQQK
.:.... ::::::::..:: :. : .: ::::::.:::::..:. : ::. .
CCDS41 LPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 VTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAV
. . :: :..::::::.::. ::.::::..: ....::: : :: .::: .::::.
CCDS41 TIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 LRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFIN
.:. :: .. :: .:.:.:.: ..::..:.. ..::::.::: :::: .:: ..
CCDS41 FRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 SENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTF
:.:. .: . .... .: .. ::. ...: : : . .::. .: .
CCDS41 EETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRV
220 230 240 250 260 270
310 320 330 340 350
pF1KB6 QMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
.. ...... ... ..... :.: .:...:.:
CCDS41 DFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA
280 290 300 310
>>CCDS3283.1 RFC4 gene_id:5984|Hs108|chr3 (363 aa)
initn: 639 init1: 347 opt: 673 Z-score: 786.0 bits: 154.0 E(32554): 1.9e-37
Smith-Waterman score: 676; 37.1% identity (67.1% similar) in 334 aa overlap (29-347:27-358)
10 20 30 40 50
pF1KB6 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYE----LPWVEKYRPVKLNEIVGNEDT
::.:. . .:::::::: ..:.. .:..
CCDS32 MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEV
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL-KDAMLELNASNDRGIDV
:. :. . ...::... ::::::::..:: :: :.:: : . .::::::..:::.:
CCDS32 VAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQV
60 70 80 90 100 110
120 130 140 150 160
pF1KB6 VRNKIKMFAQQKVTLPK--GR----HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFAL
::.:.: ::: :. . :. ::.:::::::::..:: ::::::: :::::: :
CCDS32 VREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 ACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDM
:: ..::::. :::. .:. :.: ::... .:: : .:.:. .. ...::.
CCDS32 ICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 RQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQH----CVNANIDEAYKILAHL
:.:.. :::. : ..: . :: . .. : :. : ....:. .. :
CCDS32 RKAITFLQSATRLTG--GKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 WHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLC
:.. ...... : .... : . .... . .:.:.. ::. .: : .
CCDS32 IDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVM
300 310 320 330 340 350
350
pF1KB6 QKTMAPVAS
:.
CCDS32 QQLSQNC
360
354 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:57:13 2016 done: Fri Nov 4 20:57:13 2016
Total Scan time: 2.670 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]