Result of FASTA (omim) for
pFN21AB7253
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7253, 419 aa
1>>>pF1KB7253 419 - 419 aa - 419 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4370+/-0.000354; mu= -5.8250+/- 0.022
mean_var=314.6254+/-63.726, 0's: 0 Z-trim(123.3): 14 B-trim: 14 in 1/54
Lambda= 0.072307
statistics sampled from 44674 (44689) to 44674 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.484), width: 16
Scan time: 4.750
The best scores are: opt bits E(92320)
NP_056432 (OMIM: 606902) pygopus homolog 1 isoform ( 419) 2981 324.3 3.8e-88
NP_001354735 (OMIM: 606902) pygopus homolog 1 isof ( 419) 2883 314.1 4.6e-85
NP_001317255 (OMIM: 606902) pygopus homolog 1 isof ( 419) 2883 314.1 4.6e-85
NP_612157 (OMIM: 606903) pygopus homolog 2 [Homo s ( 406) 556 71.3 5.3e-12
>>NP_056432 (OMIM: 606902) pygopus homolog 1 isoform 1 [ (419 aa)
initn: 2981 init1: 2981 opt: 2981 Z-score: 1704.0 bits: 324.3 E(92320): 3.8e-88
Smith-Waterman score: 2981; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KB7 MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
370 380 390 400 410
>>NP_001354735 (OMIM: 606902) pygopus homolog 1 isoform (419 aa)
initn: 2883 init1: 2883 opt: 2883 Z-score: 1648.8 bits: 314.1 E(92320): 4.6e-85
Smith-Waterman score: 2883; 97.1% identity (97.6% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KB7 MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
: ::. : .::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
370 380 390 400 410
>>NP_001317255 (OMIM: 606902) pygopus homolog 1 isoform (419 aa)
initn: 2883 init1: 2883 opt: 2883 Z-score: 1648.8 bits: 314.1 E(92320): 4.6e-85
Smith-Waterman score: 2883; 97.1% identity (97.6% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KB7 MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
: ::. : .::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
370 380 390 400 410
>>NP_612157 (OMIM: 606903) pygopus homolog 2 [Homo sapie (406 aa)
initn: 634 init1: 407 opt: 556 Z-score: 337.1 bits: 71.3 E(92320): 5.3e-12
Smith-Waterman score: 874; 37.6% identity (59.2% similar) in 431 aa overlap (3-418:2-405)
10 20 30 40 50
pF1KB7 MPAENSPAPAYKVSSHGGD-------SGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLS
: ..: : :. . :: : : :.:. ::.::.::.:::::.. :.
NP_612 MAASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLT
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 EYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFR-MPPHVPP
:.::::.: :::::.:::.:... . : .. :.:: : :::. . : .:::
NP_612 EFAPPPTPMVDHLVASNPFEDDFG--APKVGVAAPPFLGSPVP-FGGFRVQGGMAGQVPP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 RMSSPYCG-PYSLRNQPHPFPQNPLGMGFNRP-HAFNFGPHDNSSFGNPSYNNALSQNVN
.:. : : :: :: ::: ::.: .:: : .. .. : : .: . .:. :.:: .
NP_612 GYSTGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 MPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFG
:. .. .:. .:. :. . ...: : .: .. : : ::
NP_612 PPSGQMMPGPVGGFG---PMISPTMGQPPRAE----------LGPPSLSQRFAQPGAPFG
180 190 200 210 220
240 250 260 270 280
pF1KB7 QAKAPPPKQDFTQGATKNTNQNSSAHP-PHLNMDDTVNQSNIELKNVNRNNAVNQENSRS
: : : :: . :.: : : .. .... . : ..: :: .
NP_612 ----PSPLQRPGQG-LPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQEPHSG
230 240 250 260 270
290 300 310 320 330 340
pF1KB7 SSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDP----VYPCGI
: . :.:.: . :. . :. :: . .:.. : :. .: :::::
NP_612 SPAAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAG------GGSGPQPPPGLVYPCGA
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB7 CTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMR
: .::::::::::::::::::::: ::::::.::::::.::::::.:: :. :..: .
NP_612 CRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVY
340 350 360 370 380 390
410
pF1KB7 TRETFGPSAVGSDA
:: .: ....:
NP_612 IREGMGQLVAANDG
400
419 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:57:08 2019 done: Thu Oct 24 21:57:09 2019
Total Scan time: 4.750 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]