Result of FASTA (ccds) for
pFN21AB6862
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6862, 195 aa
1>>>pF1KB6862 195 - 195 aa - 195 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4733+/-0.000703; mu= 13.3187+/- 0.043
mean_var=71.2795+/-14.451, 0's: 0 Z-trim(110.8): 30 B-trim: 378 in 2/51
Lambda= 0.151912
statistics sampled from 11851 (11877) to 11851 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.365), width: 16
Scan time: 2.290
The best scores are: opt bits E(32554)
CCDS10708.1 PYCARD gene_id:29108|Hs108|chr16 ( 195) 1264 285.3 1.6e-77
CCDS10709.1 PYCARD gene_id:29108|Hs108|chr16 ( 176) 580 135.3 2e-32
CCDS10710.1 PYDC1 gene_id:260434|Hs108|chr16 ( 89) 344 83.5 4.2e-17
CCDS58508.1 NLRP1 gene_id:22861|Hs108|chr17 (1399) 332 81.5 2.6e-15
CCDS42245.1 NLRP1 gene_id:22861|Hs108|chr17 (1429) 332 81.5 2.6e-15
CCDS42244.1 NLRP1 gene_id:22861|Hs108|chr17 (1443) 332 81.5 2.7e-15
CCDS42246.1 NLRP1 gene_id:22861|Hs108|chr17 (1473) 332 81.5 2.7e-15
>>CCDS10708.1 PYCARD gene_id:29108|Hs108|chr16 (195 aa)
initn: 1264 init1: 1264 opt: 1264 Z-score: 1505.1 bits: 285.3 E(32554): 1.6e-77
Smith-Waterman score: 1264; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KB6 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA
130 140 150 160 170 180
190
pF1KB6 LRESQSYLVEDLERS
:::::::::::::::
CCDS10 LRESQSYLVEDLERS
190
>>CCDS10709.1 PYCARD gene_id:29108|Hs108|chr16 (176 aa)
initn: 579 init1: 579 opt: 580 Z-score: 695.5 bits: 135.3 E(32554): 2e-32
Smith-Waterman score: 1087; 90.3% identity (90.3% similar) in 195 aa overlap (1-195:1-176)
10 20 30 40 50 60
pF1KB6 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA
:::::::::::::::::::::::::::::::: :::::::::
CCDS10 LETYGAELTANVLRDMGLQEMAGQLQAATHQG-------------------LHFIDQHRA
70 80 90 100
130 140 150 160 170 180
pF1KB6 ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA
110 120 130 140 150 160
190
pF1KB6 LRESQSYLVEDLERS
:::::::::::::::
CCDS10 LRESQSYLVEDLERS
170
>>CCDS10710.1 PYDC1 gene_id:260434|Hs108|chr16 (89 aa)
initn: 344 init1: 344 opt: 344 Z-score: 420.4 bits: 83.5 E(32554): 4.2e-17
Smith-Waterman score: 344; 64.8% identity (81.8% similar) in 88 aa overlap (1-88:1-88)
10 20 30 40 50 60
pF1KB6 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
:: :.::: .::::: :::::::.:: .::::::. ::::::: ..: .:::::::. :
CCDS10 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA
: :.:::.. ::::: . : :..:: :
CCDS10 YEDYAAELVVAVLRDMRMLEEAARLQRAA
70 80
>>CCDS58508.1 NLRP1 gene_id:22861|Hs108|chr17 (1399 aa)
initn: 412 init1: 328 opt: 332 Z-score: 388.4 bits: 81.5 E(32554): 2.6e-15
Smith-Waterman score: 332; 44.5% identity (65.1% similar) in 146 aa overlap (54-192:1243-1385)
30 40 50 60 70 80
pF1KB6 KLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVS-FYLETYGAELTANVL--RDMGLQE
:.: : ::. :. . .: .: :
CCDS58 PEEVTFHLYLIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVW
1220 1230 1240 1250 1260 1270
90 100 110 120 130
pF1KB6 MA----GQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDAL
: :.:. :: . :: : .: : :::.::.: ::::::.:: .:: :
CCDS58 EALVKPGDLMPAT---TLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKL
1280 1290 1300 1310 1320
140 150 160 170 180 190
pF1KB6 YGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS
.:.::..:::. : :: : ::.::::::.. .:. ::: : :::.:.. .:. .:
CCDS58 HGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKG
1330 1340 1350 1360 1370 1380
CCDS58 SKKGLLPLSS
1390
>>CCDS42245.1 NLRP1 gene_id:22861|Hs108|chr17 (1429 aa)
initn: 412 init1: 328 opt: 332 Z-score: 388.2 bits: 81.5 E(32554): 2.6e-15
Smith-Waterman score: 332; 44.5% identity (65.1% similar) in 146 aa overlap (54-192:1273-1415)
30 40 50 60 70 80
pF1KB6 KLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVS-FYLETYGAELTANVL--RDMGLQE
:.: : ::. :. . .: .: :
CCDS42 PEEVTFHLYLIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVW
1250 1260 1270 1280 1290 1300
90 100 110 120 130
pF1KB6 MA----GQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDAL
: :.:. :: . :: : .: : :::.::.: ::::::.:: .:: :
CCDS42 EALVKPGDLMPAT---TLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKL
1310 1320 1330 1340 1350
140 150 160 170 180 190
pF1KB6 YGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS
.:.::..:::. : :: : ::.::::::.. .:. ::: : :::.:.. .:. .:
CCDS42 HGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKG
1360 1370 1380 1390 1400 1410
CCDS42 SKKGLLPLSS
1420
>>CCDS42244.1 NLRP1 gene_id:22861|Hs108|chr17 (1443 aa)
initn: 412 init1: 328 opt: 332 Z-score: 388.2 bits: 81.5 E(32554): 2.7e-15
Smith-Waterman score: 332; 44.5% identity (65.1% similar) in 146 aa overlap (54-192:1287-1429)
30 40 50 60 70 80
pF1KB6 KLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVS-FYLETYGAELTANVL--RDMGLQE
:.: : ::. :. . .: .: :
CCDS42 GCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVW
1260 1270 1280 1290 1300 1310
90 100 110 120 130
pF1KB6 MA----GQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDAL
: :.:. :: . :: : .: : :::.::.: ::::::.:: .:: :
CCDS42 EALVKPGDLMPAT---TLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKL
1320 1330 1340 1350 1360 1370
140 150 160 170 180 190
pF1KB6 YGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS
.:.::..:::. : :: : ::.::::::.. .:. ::: : :::.:.. .:. .:
CCDS42 HGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKG
1380 1390 1400 1410 1420 1430
CCDS42 SKKGLLPLSS
1440
>>CCDS42246.1 NLRP1 gene_id:22861|Hs108|chr17 (1473 aa)
initn: 412 init1: 328 opt: 332 Z-score: 388.0 bits: 81.5 E(32554): 2.7e-15
Smith-Waterman score: 332; 44.5% identity (65.1% similar) in 146 aa overlap (54-192:1317-1459)
30 40 50 60 70 80
pF1KB6 KLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVS-FYLETYGAELTANVL--RDMGLQE
:.: : ::. :. . .: .: :
CCDS42 GCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVW
1290 1300 1310 1320 1330 1340
90 100 110 120 130
pF1KB6 MA----GQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDAL
: :.:. :: . :: : .: : :::.::.: ::::::.:: .:: :
CCDS42 EALVKPGDLMPAT---TLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKL
1350 1360 1370 1380 1390 1400
140 150 160 170 180 190
pF1KB6 YGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS
.:.::..:::. : :: : ::.::::::.. .:. ::: : :::.:.. .:. .:
CCDS42 HGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKG
1410 1420 1430 1440 1450 1460
CCDS42 SKKGLLPLSS
1470
195 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:06:26 2016 done: Sat Nov 5 00:06:27 2016
Total Scan time: 2.290 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]