Result of FASTA (omim) for
pFN21AE0172
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0172, 317 aa
1>>>pF1KE0172 317 - 317 aa - 317 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7094+/-0.000338; mu= 19.4602+/- 0.021
mean_var=69.9581+/-14.038, 0's: 0 Z-trim(113.9): 21 B-trim: 44 in 1/55
Lambda= 0.153340
statistics sampled from 23434 (23441) to 23434 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.275), width: 16
Scan time: 7.040
The best scores are: opt bits E(85289)
NP_005389 (OMIM: 602999) protein phosphatase 1 reg ( 317) 2202 496.1 3.8e-140
NP_078883 (OMIM: 610541) protein phosphatase 1 reg ( 285) 773 180.0 5.1e-45
XP_006716316 (OMIM: 610541) PREDICTED: protein pho ( 285) 773 180.0 5.1e-45
NP_001188258 (OMIM: 610541) protein phosphatase 1 ( 285) 773 180.0 5.1e-45
XP_016869324 (OMIM: 610541) PREDICTED: protein pho ( 285) 773 180.0 5.1e-45
NP_006233 (OMIM: 603326) protein phosphatase 1 reg ( 299) 340 84.2 3.6e-16
NP_002702 (OMIM: 125853,600917,604367) protein pho (1122) 337 84.1 1.5e-15
>>NP_005389 (OMIM: 602999) protein phosphatase 1 regulat (317 aa)
initn: 2202 init1: 2202 opt: 2202 Z-score: 2637.1 bits: 496.1 E(85289): 3.8e-140
Smith-Waterman score: 2202; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL
250 260 270 280 290 300
310
pF1KE0 FPEWQSWGRMENLASYR
:::::::::::::::::
NP_005 FPEWQSWGRMENLASYR
310
>>NP_078883 (OMIM: 610541) protein phosphatase 1 regulat (285 aa)
initn: 689 init1: 529 opt: 773 Z-score: 929.2 bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)
10 20 30 40 50
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
.: ::. .: :.: : ... ..: . . :::.
NP_078 MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
10 20 30
60 70 80 90 100 110
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
:... :..:... .....:::: :::..::.:: ..:::.. ..: :. :..
NP_078 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
.: : .: : ....::: :::.:::.::...: . :::::: :......:::::.:
NP_078 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
..::: :.::.:::.::.::: : :.:..:.:.: ::::: :.:: : . ...:: .
NP_078 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
:. :::..::.: :.::::.... : ..: . : ...: . ::::: .
NP_078 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
220 230 240 250 260
300 310
pF1KE0 SGLFPEWQSWGRMENLASYR
:::::: :. .:.:. :
NP_078 YGLFPEWPSYLGYEKLGPYY
270 280
>>XP_006716316 (OMIM: 610541) PREDICTED: protein phospha (285 aa)
initn: 689 init1: 529 opt: 773 Z-score: 929.2 bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)
10 20 30 40 50
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
.: ::. .: :.: : ... ..: . . :::.
XP_006 MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
10 20 30
60 70 80 90 100 110
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
:... :..:... .....:::: :::..::.:: ..:::.. ..: :. :..
XP_006 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
.: : .: : ....::: :::.:::.::...: . :::::: :......:::::.:
XP_006 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
..::: :.::.:::.::.::: : :.:..:.:.: ::::: :.:: : . ...:: .
XP_006 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
:. :::..::.: :.::::.... : ..: . : ...: . ::::: .
XP_006 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
220 230 240 250 260
300 310
pF1KE0 SGLFPEWQSWGRMENLASYR
:::::: :. .:.:. :
XP_006 YGLFPEWPSYLGYEKLGPYY
270 280
>>NP_001188258 (OMIM: 610541) protein phosphatase 1 regu (285 aa)
initn: 689 init1: 529 opt: 773 Z-score: 929.2 bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)
10 20 30 40 50
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
.: ::. .: :.: : ... ..: . . :::.
NP_001 MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
10 20 30
60 70 80 90 100 110
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
:... :..:... .....:::: :::..::.:: ..:::.. ..: :. :..
NP_001 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
.: : .: : ....::: :::.:::.::...: . :::::: :......:::::.:
NP_001 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
..::: :.::.:::.::.::: : :.:..:.:.: ::::: :.:: : . ...:: .
NP_001 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
:. :::..::.: :.::::.... : ..: . : ...: . ::::: .
NP_001 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
220 230 240 250 260
300 310
pF1KE0 SGLFPEWQSWGRMENLASYR
:::::: :. .:.:. :
NP_001 YGLFPEWPSYLGYEKLGPYY
270 280
>>XP_016869324 (OMIM: 610541) PREDICTED: protein phospha (285 aa)
initn: 689 init1: 529 opt: 773 Z-score: 929.2 bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)
10 20 30 40 50
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
.: ::. .: :.: : ... ..: . . :::.
XP_016 MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
10 20 30
60 70 80 90 100 110
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
:... :..:... .....:::: :::..::.:: ..:::.. ..: :. :..
XP_016 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
.: : .: : ....::: :::.:::.::...: . :::::: :......:::::.:
XP_016 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
..::: :.::.:::.::.::: : :.:..:.:.: ::::: :.:: : . ...:: .
XP_016 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
:. :::..::.: :.::::.... : ..: . : ...: . ::::: .
XP_016 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
220 230 240 250 260
300 310
pF1KE0 SGLFPEWQSWGRMENLASYR
:::::: :. .:.:. :
XP_016 YGLFPEWPSYLGYEKLGPYY
270 280
>>NP_006233 (OMIM: 603326) protein phosphatase 1 regulat (299 aa)
initn: 270 init1: 155 opt: 340 Z-score: 411.2 bits: 84.2 E(85289): 3.6e-16
Smith-Waterman score: 344; 29.5% identity (58.5% similar) in 275 aa overlap (10-265:19-289)
10 20 30 40
pF1KE0 MSCTRMIQVLDPRPLTS-SVMPVDVAM--RLCL-----AHSPPVKSFLGPY
: :: :. : . ::. : : ...:: .
NP_006 MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 DEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKK-RVVFADSKGLSLTAIHVFS
: : .. . . : : . ..:: . : . ..: :: :::. :: :. ..::
NP_006 DPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVF-
70 80 90 100 110
110 120 130 140 150
pF1KE0 DLPEEPAWDLQ-FDLLDLN-DISSALKHHEE--KNLILDFPQPSTDYLSFRSHFQKNFVC
. ..:. :. .. : .: :. . . : . :. ::: : .. .: ..:...::
NP_006 NAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPP-VEAADFGERLQRQLVC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 LENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYG--GTDSDTF
:: . .. ..:::.: ::.:::.: .: ::..:.. : . .. : ::. :.:
NP_006 LERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRS-THEAVARWRGPAGPEGTE-DVF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 SFAIDLPP-VIPTEQKIEFCISYHANGQVFWDNNDGQNYRIV---HVQWKPDGVQTQMAP
.:.. .:: .. ....: . :.. : .::::: ..: .. :. : :
NP_006 TFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWI
240 250 260 270 280 290
280 290 300 310
pF1KE0 QDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR
NP_006 HFI
>>NP_002702 (OMIM: 125853,600917,604367) protein phospha (1122 aa)
initn: 272 init1: 229 opt: 337 Z-score: 400.2 bits: 84.1 E(85289): 1.5e-15
Smith-Waterman score: 337; 33.7% identity (63.2% similar) in 190 aa overlap (83-267:62-242)
60 70 80 90 100 110
pF1KE0 NKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDL
.:: :::: :..:.... : : : :. .
NP_002 TFQPGFSPQPSRRGSDSSEDIYLDTPSSGTRRVSFADSFGFNLVSVKEF-DCWELPSAST
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 QFDLLDLNDISSALKHHEEKNL--ILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVT
::: .. . : :: : ..:.:. . : .. . ..:: .. . : ..
NP_002 TFDL------GTDIFHTEEYVLAPLFDLPSSKEDLMQ-QLQIQKAILESTESLLGSTSIK
100 110 120 130 140
180 190 200 210 220
pF1KE0 GTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDL-PPVIPTE
: ..: :::::: : .:...:.:... :. :. : : ..: ::: : : ::
NP_002 GIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNSCDG-ETDQFSFKIVLVPPYQKDG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE0 QKIEFCISYHANGQVFWDNNDGQNYRIV--HVQWKPDGVQTQMAPQDCAFHQTSPKTELE
.:.:::: :... .::.::.: :: .. . . .:. :.
NP_002 SKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEPVKPWKEVPNRQIKGCLKVKSSK
210 220 230 240 250 260
290 300 310
pF1KE0 STIFGSPRLASGLFPEWQSWGRMENLASYR
NP_002 EESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELM
270 280 290 300 310 320
317 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:55:06 2016 done: Thu Nov 3 22:55:07 2016
Total Scan time: 7.040 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]